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    Substituted phenylalkanoic acids and derivatives
    1.
    发明授权
    Substituted phenylalkanoic acids and derivatives 失效
    取代的苯基链烷酸及其衍生物

    公开(公告)号：US3978071A

    公开(公告)日：1976-08-31

    申请号：US486728

    申请日：1974-07-08

    申请人： Michio Nakanishi ,  Tomio Muro ,  Tohru Nakao ,  Kiyoshi Ogawa

    发明人： Michio Nakanishi ,  Tomio Muro ,  Tohru Nakao ,  Kiyoshi Ogawa

    IPC分类号： C07D471/04 ,  C07D487/04 ,  C07D513/04

    CPC分类号： C07D513/04 ,  C07D471/04 ,  C07D487/04

    摘要： Substituted phenylalkanoic acids and derivatives thereof of the formula: ##SPC1##Wherein each of R.sup.1 and R.sup.2 is a hydrogen atom or an alkyl group having 1 to 4 carbon atoms; each of X.sup.1 and X.sup.2 is a hydrogen atom, a halogen atom, an alkyl group having 1 to 4 carbon atoms or an alkoxy group having 1 to 4 carbon atoms; Y is COOH, COOR (wherein R is an alkyl group having 1 to 4 carbon atoms), CONH.sub.2, CSNH.sub.2, CN or COZ--A--N(R.sup.3)(R.sup.4) (wherein Z is an oxygen atom or an imino group, A is an alkylene group having 2 to 4 carbon atoms and each of R.sup.3 and R.sup.4 is a hydrogen atom or an alkyl group having 1 to 4 carbon atoms, or R.sup.3 and R.sup.4 together with the adjacent nitrogen atom form a saturated heterocycle selected from pyrrolidine, piperidine, morpholine, piperazine and piperazine substituted by an alkyl group having 1 to 4 carbon atoms at the 4-position; and ring P represents a pyridine ring, a pyrimidine ring or a thiazole ring; and pharmaceutically acceptable salts thereof are useful as analgesics, anti-pyrestics and anti-inflammatory agents.

    摘要翻译： 取代的苯基链烷酸及其下式的衍生物：

    1-[Methylated piperidino(and pyrrolidin-1-yl)]-3-(substituted phenoxy)-2propanols
    2.
    发明授权
    1-[Methylated piperidino(and pyrrolidin-1-yl)]-3-(substituted phenoxy)-2propanols 失效
    1- {8-甲基哌啶子基（和吡咯烷-1-基）{9-3（取代的苯氧基）-2-丙醇

    公开(公告)号：US3954776A

    公开(公告)日：1976-05-04

    申请号：US499948

    申请日：1974-08-23

    申请人： Tomio Muro ,  Sogo Fukuzawa ,  Yasuaki Chihara ,  Tohru Nakao ,  Kiyoshi Ogawa

    发明人： Tomio Muro ,  Sogo Fukuzawa ,  Yasuaki Chihara ,  Tohru Nakao ,  Kiyoshi Ogawa

    IPC分类号： C07D295/092 ,  C07D211/14

    CPC分类号： C07D295/088 ,  Y10S514/818 ,  Y10S514/821

    摘要： 1-[Methylated piperidino (and pyrrolidin-1-yl)]-3-(substituted phenoxy)-2-propanols of the formula: ##SPC1##Wherein R is a 2-thienylmethyl group, a 2-pyridylmethyl group, a 2-pyridyl group, a tetrahydrofurfuryloxy group, a furfuryloxy group, a 2-thienylmethoxy group, a 2-pyridyloxy group or a group of the formula R.sup.5 --X--A--O-- wherein R.sup.5 is a lower alkyl group, X is --O--, --S-- or --SO.sub.2 --, and A is a lower alkylene group or a --CH.sub.2 --C.ident.C--CH.sub.2 -- group, R.sup.1 is a hydrogen atom, a lower alkyl group or a halogen atom, R.sup.2, R.sup.3 and R.sup.4 are each a hydrogen atom or a methyl group, and n is zero or 1, and pharmaceutically acceptable acid addition and quarternary ammonium salts thereof are disclosed. They exhibit antiarrhythmic action, local anaesthetic action, analgesic action and gastric juice secretion inhibiting action.

    摘要翻译： 1- [甲基化哌啶子基（和吡咯烷-1-基）] - 3-（取代的苯氧基）-2-丙醇，其具有下式：

    Seat belt retractor
    6.
    发明授权
    Seat belt retractor 有权
    安全带卷收器

    公开(公告)号：US08286903B2

    公开(公告)日：2012-10-16

    申请号：US12945478

    申请日：2010-11-12

    申请人： Kiyoshi Ogawa ,  Masuo Matsuki

    发明人： Kiyoshi Ogawa ,  Masuo Matsuki

    IPC分类号： B65H75/48

    CPC分类号： B60R22/4676 ,  B60R2022/287 ,  B60R2022/289

    摘要： A retractor includes a slide nut that is caused to slide toward a tread head while rotating by a mesh between a first male screw groove and a female screw groove when the tread head is locked and a spindle rotates in a direction for unreeling a webbing, and a slider that is caused to slide toward the slide nut by a mesh between the female screw groove and a second male screw groove. A torsional rigidity of a second shaft part of a torsion bar is larger than that of a first shaft part, and a play is eliminated before a gap such that the slide nut and the slider are integrated.

    摘要翻译： 牵开器包括滑动螺母，当滑动螺母被锁定并且主轴沿用于松开织带的方向旋转时，滑动螺母在通过第一外螺纹槽和内螺纹槽之间的网转动的同时朝向胎面头滑动，以及 滑动件通过内螺纹槽和第二外螺纹槽之间的网状物向滑动螺母滑动。 扭杆的第二轴部的扭转刚性大于第一轴部的扭转刚性，并且在滑动螺母和滑块一体化的间隙之前消除了间隙。

    Mass Spectrometer
    7.
    发明申请
    Mass Spectrometer 审中-公开
    质谱仪

    公开(公告)号：US20120132799A1

    公开(公告)日：2012-05-31

    申请号：US13260061

    申请日：2009-03-31

    申请人： Kazuteru Takahashi ,  Kiyoshi Ogawa ,  Mitsutoshi Setou

    发明人： Kazuteru Takahashi ,  Kiyoshi Ogawa ,  Mitsutoshi Setou

    IPC分类号： H01J49/26

    CPC分类号： H01J49/0004 ,  G01N2001/045

    摘要： A samples stage (2) on which a sample (4) is placed can reciprocally move along a guide (5) by a driving mechanism. An image taken by an imaging unit (7) when the sample stage (2) is at an observation position (A) is processed by an image processor (34) and is displayed on a window of a display unit (38). When an analysis operator specifies a measurement area by an operation unit (37), a controller (3) moves, through a stage driver (33), the stage (2) to a sample operation position (B) and a matrix is applied to the specified measurement area by an ejector (9). After that, the stage (2) is moved to an analysis position (C) and a laser light is delivered onto the measurement area on the sample (4) to which the matrix was applied, and the ionization by the MALDI method is performed. This eliminates the need to take out the sample from the apparatus to apply the matrix after the measurement point or measurement area is determined based on a microscopic observation of the sample. Accordingly, the efficiency of the measurement can be increased, and since no positional error of the sample occurs, it is possible to perform an imaging mass analysis for a measurement area of interest with high positional accuracy.

    摘要翻译： 其上放置有样品（4）的样品台（2）可以通过驱动机构沿引导件（5）往复运动。 当样本台（2）处于观察位置（A）时由成像单元（7）拍摄的图像由图像处理器（34）处理并显示在显示单元（38）的窗口上。 当分析操作者通过操作单元（37）指定测量区域时，控制器（3）通过平台驱动器（33）将平台（2）移动到采样操作位置（B），并将矩阵应用于 由喷射器（9）指定的测量区域。 之后，将阶段（2）移动到分析位置（C），并将激光输送到施加了矩阵的样品（4）的测量区域上，并通过MALDI方法进行电离。 这消除了在基于样品的显微镜观察确定测量点或测量区域之后，从设备中取出样品以施加基质的需要。 因此，可以提高测量效率，并且由于不发生样本的位置误差，因此可以以高位置精度对感兴趣的测量区域进行成像质量分析。

    SEATBELT RETRACTOR
    8.
    发明申请
    SEATBELT RETRACTOR 有权
    座椅延伸器

    公开(公告)号：US20120043407A1

    公开(公告)日：2012-02-23

    申请号：US13264870

    申请日：2010-03-31

    申请人： Kiyoshi Ogawa ,  Katsuyasu Ono ,  Yuichi Hamano

    发明人： Kiyoshi Ogawa ,  Katsuyasu Ono ,  Yuichi Hamano

    IPC分类号： B60R22/36

    CPC分类号： B60R22/4628 ,  B60R2022/287 ,  B60R2022/4642

    摘要： A seatbelt retractor having a switching device with a gas generator and a switch housing having a gas generator housing portion for accommodating the gas generator and a gas flow path that communicates with the gas generator housing portion so that gas generated by the gas generator passes through the gas flow path. Further, the gas generator housing portion and the gas flow path are formed in the switch housing in a curved shape, and a die-cut hole extending in a direction of the gas flow path on an opposite side of the gas flow path to the gas generator housing portion is blocked from the gas flow path by the gas generator.

    摘要翻译： 一种安全带卷收器，具有具有气体发生器的开关装置和具有用于容纳气体发生器的气体发生器容纳部分和与气体发生器壳体部分连通的气体流路的开关壳体，使得由气体发生器产生的气体通过 气体流路。 此外，气体发生器壳体部分和气体流动通道在开关壳体中形成为弯曲形状，并且在气体流动路径的与气体的气体流动路径相对的一侧上延伸的冲切孔 发电机壳体部分被气体发生器从气体流动路径阻挡。

    Mass spectrometer
    9.
    发明授权
    Mass spectrometer 有权
    质谱仪

    公开(公告)号：US08058610B2

    公开(公告)日：2011-11-15

    申请号：US12515674

    申请日：2006-12-05

    申请人： Takahiro Harada ,  Sadao Takeuchi ,  Kiyoshi Ogawa ,  Mitsutoshi Setou

    发明人： Takahiro Harada ,  Sadao Takeuchi ,  Kiyoshi Ogawa ,  Mitsutoshi Setou

    IPC分类号： H01J49/04 ,  H01J49/00

    CPC分类号： H01J49/164

    摘要： A sample plate 3 with a sample 4 placed thereon is initially set on a stage 2, and a visual image of the sample is taken with a CCD camera 14. This image is stored in an image data memory 23. Then, an operator removes the sample plate 3, sprays a matrix for a MALDI process onto the sample 4 and replaces the plate onto the stage 2. After that, when a predetermined operation is made, a clear image of the sample taken before the application of the matrix is shown on a display unit 24. On this image, the operator specifies a point or area for the analysis. The sample 4 may have been displaced due to the removal and replacement of the plate 3. Accordingly, an image analyzer 44 calculates the direction and magnitude of the displacement, for example, by recognizing the position of the markings provided on the sample plate 3. A displacement corrector 42 computes coordinate values in which the displacement is corrected. Thus, even if a displacement occurs, the mass analysis can be accurately performed on the point or area of the actual sample as specified on the clear visual image taken before the application of the matrix.

    摘要翻译： 将样品4放置在其上的样品板3初始设置在载物台2上，用CCD照相机14拍摄样品的视觉图像。该图像存储在图像数据存储器23中。然后，操作者将 样品板3将MALDI工艺的矩阵喷射到样品4上，并将该板替换到载物台2上。之后，当进行预定的操作时，在施加矩阵之前拍摄的样品的清晰图像显示在 在该图像上，操作者指定用于分析的点或区域。 样品4可能由于板3的移除和更换而被移动。因此，图像分析器44例如通过识别设置在样品板3上的标记的位置来计算位移的方向和大小。 位移校正器42计算校正位移的坐标值。 因此，即使发生位移，也可以在施加矩阵之前在清晰的视觉图像上指定的实际样品的点或面积上精确地进行质量分析。

    SEAT BELT RETRACTOR
    10.
    发明申请
    SEAT BELT RETRACTOR 有权
    座椅皮带扣

    公开(公告)号：US20110011969A1

    公开(公告)日：2011-01-20

    申请号：US12922839

    申请日：2009-04-03

    申请人： Kiyoshi Ogawa

    发明人： Kiyoshi Ogawa

    IPC分类号： B60R22/46

    CPC分类号： B60R22/4676 ,  B60R22/4633 ,  B60R2022/4642

    摘要： A seat belt retractor (10) is provided with: a spindle (12) around which a seat belt (B) is wound; a torsion bar (17) disposed in a cavity (27) of the spindle (12), an axial end portion of the torsion bar (17) being attached to an axial end portion of the spindle (12); a first pretensioner (16) that is attached to the spindle (12) at least during a collision so as to cause the spindle (12) to rotate in a retraction direction using a gas pressure; and a second pretensioner (18) that is attached to another axial end portion of the torsion bar (17) at least during a collision so as to cause the spindle (12) to rotate in the retraction direction via the torsion bar (17) using the gas pressure.

    摘要翻译： 安全带卷收器（10）设有：一个主轴（12），一个安全带（B）绕在该主轴上; 设置在所述心轴（12）的空腔（27）中的扭杆（17），所述扭杆（17）的轴向端部附接到所述心轴（12）的轴向端部; 至少在碰撞期间附接到所述主轴（12）的第一预张紧器（16），以便使所述主轴（12）使用气压在回缩方向上旋转; 以及至少在碰撞期间附接到所述扭杆（17）的另一轴向端部的第二预张紧器（18），以便使所述主轴（12）经由所述扭杆（17）沿所述缩回方向旋转，所述第二预紧器（18）使用 气压。