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公开(公告)号：US6074381A
公开(公告)日：2000-06-13
申请号：US177668
申请日：1998-10-22
CPC分类号： A61F2/958 , A61F2002/9522 , Y10T29/53657
摘要： A stent loading apparatus for loading a deformable stent onto a deployment device. The stent loading apparatus includes an elastic member defining a passage therein formed for longitudinal receipt of the deformable stent in an uncrimped condition. A first member includes a first compression region; and a second member includes a second compression region positioned substantially adjacent the first compression region at a first position. At this first position, the elastic member and the deformable stent in the uncrimped condition may be received between the opposed first and second compression regions. The first compression region and the second compression region are further configured to provide rolling support and compression of the elastic member during relative movement between the first position and a second position for rolling radial compression of the deformable stent onto the deployment device.
摘要翻译： 一种用于将可变形支架装载到展开装置上的支架装载装置。 支架装载装置包括限定其中形成的通道的弹性构件，用于在未卷曲状态下纵向容纳可变形支架。 第一构件包括第一压缩区域; 并且第二构件包括在第一位置处基本上邻近所述第一压缩区域定位的第二压缩区域。 在该第一位置，可以在相对的第一和第二压缩区域之间容纳弹性构件和未松脱状态的可变形支架。 第一压缩区域和第二压缩区域进一步构造成在第一位置和第二位置之间的相对移动期间提供弹性构件的滚动支撑和压缩，用于将可变形支架的径向压缩滚动到展开装置上。
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公开(公告)号：US06309383B1
公开(公告)日：2001-10-30
申请号：US09488187
申请日：2000-01-20
IPC分类号： A61B1700
CPC分类号： B25B7/00 , A61F2/958 , A61F2002/9522 , A61F2210/0095 , B25B27/146
摘要： A stent crimping apparatus for crimping a deformable radioactive stent onto a deployment device which includes a first jaw member defining a shielded first compression surface, and an opposed, second jaw member defining a shielded second compression surface oriented opposite the first compression surface. The first and second compression surfaces are adapted to collectively form an elongated guide bore formed for axial receipt of the deformable stent and the deployment device therein. To protect against exposure to the radioactive stent, a shield assembly is provided defining an opening into a bore therein which is formed and dimensioned for longitudinal receipt of the deformable stent in an uncrimped condition. A shield assembly defines an opening into the bore, and cooperates with the first and second jaw members to substantially prevent radioactive particles emitted by the radioactive stent from passing out of the crimping apparatus. An operating mechanism is operatively coupled to the first and second jaw members for selective movement between a loading condition and a crimping condition. In the loading condition, the uncrimped stent and the deployment device may be inserted through the opening and into the bore. In the crimping condition, the deformable stent is radially compressed onto the deployment device between the first and second compression surfaces.
摘要翻译： 一种用于将可变形放射性支架卷曲到展开装置上的支架压接装置，所述展开装置包括限定屏蔽的第一压缩表面的第一钳口构件和限定与第一压缩表面相对定向的屏蔽的第二压缩表面的相对的第二钳口构件。 第一和第二压缩表面适于共同地形成用于轴向容纳可变形支架和其中的展开装置的细长导向孔。 为了防止暴露于放射性支架，设置屏蔽组件，其限定到其中的孔中的开口，其中形成并确定尺寸以使未变形状态的可变形支架的纵向接收。 屏蔽组件限定了孔内的开口，并且与第一和第二钳口构件配合，以基本上防止由放射性支架发射的放射性颗粒从压接装置传出。 操作机构可操作地联接到第一和第二钳口构件，用于在负载状态和压接状态之间的选择性运动。 在装载状态下，未卷曲的支架和展开装置可以通过开口插入孔中。 在卷曲状态下，可变形支架在第一和第二压缩表面之间径向压缩到展开装置上。
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3.发明授权公开(公告)号：US06190303B1
公开(公告)日：2001-02-20
申请号：US09301442
申请日：1999-04-28
IPC分类号： A61N500
CPC分类号： G21F5/018 , A61N5/1002
摘要： A radiation shield assembly (30) for a radioactive stent (11) mounted onto a deployment portion (20) of a delivery apparatus (12) including a relatively thin, elongated tube member (69) having a wall (70) defining a receiving passage (72) formed and dimensioned for axial receipt of the stent mounted onto the deployment portion therein to substantially prevent direct contact with the stent (11). A removal structure (71) cooperating with the wall (70) of the tube member (69) for longitudinal severing thereof to enable selective removal of the tube member from the delivery apparatus (12) for deployment use thereof.
摘要翻译： 一种用于放射性支架（11）的辐射屏蔽组件（30），其安装在输送设备（12）的展开部分（20）上，该输送设备（12）包括相对薄的细长管构件（69），所述管构件具有限定接收通道 （72）的形状和尺寸用于轴支承安装在其上的展开部分上的支架，以基本上防止与支架（11）的直接接触。 与所述管构件（69）的壁（70）配合以用于其纵向切断的移除结构（71），以便能够从所述输送装置（12）中选择性地移除所述管构件以用于其部署。
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公开(公告)号：US06648900B2
公开(公告)日：2003-11-18
申请号：US09997619
申请日：2001-11-28
申请人： Sidney D. Fleischman , Russell A. Houser , James G. Whayne , Thomas H. Campbell , Patrick M. Owens
发明人： Sidney D. Fleischman , Russell A. Houser , James G. Whayne , Thomas H. Campbell , Patrick M. Owens
IPC分类号： A61B1708
CPC分类号： A61F2/064 , A61B17/11 , A61B17/32053 , A61B2017/00867 , A61B2017/1107 , A61B2017/1135 , A61B2017/306 , A61F2/91
摘要： An end-side anastomosis system including a fitting including a base for attachment to a graft, the base be configured to form a seal with an opening in a host vessel wall a leading petal having a cross-section with a radius of curvature approximating a radius of curvature of the host vessel, the leading petal being configured to dilate the host vessel wall opening while advancing the fitting through the opening and a rear petal, the rear petal being deflectable to be advanced through the host vessel opening.
摘要翻译： 一种端侧吻合系统，包括包括用于附接到移植物的基部的配件，所述基座被构造成与主容器壁中的开口形成具有近似半径的曲率半径的横截面的前导花瓣的密封件 所述前花瓣被构造成在通过所述开口推进所述配件和后花瓣时扩张所述主容器壁开口，所述后花瓣可偏转以前进通过所述主容器开口。
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公开(公告)号：US06648901B2
公开(公告)日：2003-11-18
申请号：US09730366
申请日：2000-12-05
申请人： Sidney D. Fleischman , Russell A. Houser , James G. Whayne , Thomas H. Campbell , Patrick M. Owens
发明人： Sidney D. Fleischman , Russell A. Houser , James G. Whayne , Thomas H. Campbell , Patrick M. Owens
IPC分类号： A61F206
CPC分类号： A61F2/064 , A61B17/11 , A61B17/32053 , A61B2017/00867 , A61B2017/1107 , A61B2017/1135 , A61B2017/306 , A61F2/91
摘要： An end-side anastomosis system including a fitting comprising: a base for attachment to a graft, said base be configured to form a seal with an opening in a host vessel wall; a leading petal having a cross-section with a radius of curvature approximating a radius of curvature of the host vessel, said leading petal being configured to dilate the host vessel wall opening while advancing said fitting through the opening; and a rear petal, said rear petal being deflectable to be advanced through the host vessel opening.
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公开(公告)号：US5788692A
公开(公告)日：1998-08-04
申请号：US497941
申请日：1995-06-30
CPC分类号： A61B18/1815 , A61B18/18 , A61B18/1492 , A61B2018/00946 , A61B2018/1861
摘要： A variety of improved ablation catheters and methods for using such catheters are described. In one embodiment, the catheter includes a plurality of longitudinally spaced split electrode bands that are provided near the distal end of the catheter to monitor electrophysiological signals in the patient. The electrode bands each include a plurality of electrically isolated electrode segments. The number of electrode segments in each band may be widely varied, as may the number of electrode bands. In another embodiment, the catheter has a transducer that is movable longitudinally relative to the flexible tubular member. In one embodiment, the transducer is carried at the distal end of the transmission line and the transmission line is slideably received within the flexible tubular member such that the transducer can be positioned longitudinally relative to the electrode bands. In still another embodiment, the electrodes are ion implanted on the flexible tubular member. The described catheter is introduced into a patient's body such that a distal portion of the catheter is positioned in a vessel or chamber of an organ such as the heart. The electrodes are used to monitor electrophysiological signals and an appropriate ablation position is identified based at least in part on the monitored electrophysiological signals. The transducer is then positioned at the identified ablation position and electromagnetic energy is applied to a transducer through a transmission line to cause ablation of tissue in a region adjacent the identified ablation position.
摘要翻译： 描述了各种改进的消融导管和使用这种导管的方法。 在一个实施例中，导管包括多个纵向隔开的分开的电极带，其设置在导管的远端附近以监测患者的电生理信号。 电极带各自包括多个电隔离的电极段。 每个带中的电极段的数量可以是广泛变化的，如电极带的数量。 在另一个实施例中，导管具有可相对于柔性管状构件纵向移动的换能器。 在一个实施例中，传感器被承载在传输线的远端，并且传输线可滑动地容纳在柔性管状构件内，使得换能器可相对于电极带纵向定位。 在另一个实施例中，电极被离子注入到柔性管状构件上。 将所描述的导管引入患者体内，使得导管的远端部分位于诸如心脏的器官的血管或腔室中。 电极用于监测电生理信号，并且至少部分地基于监测的电生理信号来识别适当的消融位置。 然后将换能器定位在所识别的消融位置，并且通过传输线将电磁能量施加到换能器，以在与所识别的消融位置相邻的区域中的组织消融。
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公开(公告)号：US6090035A
公开(公告)日：2000-07-18
申请号：US273072
申请日：1999-03-19
CPC分类号： A61N5/1002 , A61F2/95 , A61F2002/9522
摘要： A stent loading apparatus for loading a self-expanding radioactive stent into a bore of a deployment device in a compressed condition including a storage device defining an elongated first passage formed and dimensioned for sliding receipt of the stent therein. The first passage extends through the storage device and terminates at a stent transfer opening of a proximal coupling end thereof. A radiation shield defines an elongated second passage which terminates at a distal opening of a distal coupling end thereof. The distal coupling end of the radiation shield and the proximal coupling end of the storage device cooperate to align the distal opening of the shield in receiving communication with the stent transfer opening of the storage device. The second passage of the shield is formed and dimensioned for receipt of the deployment device therein in a manner positioning a mouth of the deployment device bore substantially adjacent the stent transfer opening of the storage device. Upon urging of the stent in a direction toward the shield, the radioactive stent may be slideably transferred from the first passage and into the mouth of the bore for retainment therein in the compressed condition.
摘要翻译： 一种用于将自扩张放射性支架装载到压缩状态的展开装置的孔中的支架装载装置，所述支架装置包括限定长形第一通道的存储装置，所述第一通道形成并确定尺寸用于在其中滑动支架。 第一通道延伸穿过存储装置并且终止于其近端联接端的支架传送开口。 辐射屏蔽限定细长的第二通道，其终止于其远端联接端的远端开口处。 辐射屏蔽的远端联接端和存储装置的近端联接端配合以使屏蔽件的远端开口与存储装置的支架传送开口接通。 屏蔽件的第二通道被形成并且被设计成用于以这样的方式接收其中的展开装置，即定位装置孔的口基本上邻近存储装置的支架传送开口。 当沿着屏蔽方向推动支架时，放射性支架可以从第一通道可滑动地转移到孔的口中以在压缩状态下保持在其中。
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公开(公告)号：US06245026B1
公开(公告)日：2001-06-12
申请号：US09346072
申请日：1999-07-01
IPC分类号： A61B1000
CPC分类号： A61B5/01 , A61B5/015 , A61B5/6853 , A61B8/12 , A61B8/4461 , A61N5/1002
摘要： A variety of improved thermal mapping catheters are disclosed which are capable of sensing and mapping thermal variations within body vessels. In embodiments directed at vascular applications, the catheters are capable of detecting temperature variations in atherosclerotic plaque, on the atherosclerotic plaque surface, and on the arterial wall of aneurysms and other vascular lesions of the human vasculature. In one aspect of the invention, a combined thermal mapping and drug delivery catheter is provided. In this embodiment a plurality of thermal sensors are combined with at least one infusion port suitable for delivering therapeutic agents into a vessel. In some embodiments, at least some of the infusion ports are located between adjacent thermal sensors. The described catheters may be used in a variety of new applications and medical diagnostic and treatment techniques.
摘要翻译： 公开了能够感测和映射体内血管中的热变化的各种改进的热导图。 在针对血管应用的实施例中，导管能够检测动脉粥样硬化斑块，动脉粥样硬化斑块表面以及动脉瘤的动脉壁和人脉管系统的其它血管损伤的温度变化。 在本发明的一个方面，提供组合的热图和药物输送导管。 在该实施例中，多个热传感器与适合于将治疗剂递送到血管中的至少一个输注端口组合。 在一些实施例中，至少一些输注端口位于相邻的热传感器之间。 所描述的导管可以用于各种新的应用和医疗诊断和治疗技术。
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公开(公告)号：US6132358A
公开(公告)日：2000-10-17
申请号：US236770
申请日：1999-01-25
CPC分类号： G21F5/018 , A61N5/1002
摘要： A radiation shield assembly (30) for a radioactive stent (11) which includes a first shield member (31) having a first mating surface (32) and a second shield member (33) having an opposed second mating surface (35). When the two shield members are removably coupled to one another, the first mating surface (32) cooperates with the opposing second mating surface (35) to substantially radially enclose the stent (11) therebetween, and substantially prevent the direct passage of radioisotopes emitted from the stent radially out of the shield assembly (30).
摘要翻译： 一种用于放射性支架（11）的辐射屏蔽组件（30），其包括具有第一配合表面（32）的第一屏蔽构件（31）和具有相对的第二配合表面（35）的第二屏蔽构件。 当两个屏蔽构件可拆卸地彼此联接时，第一配合表面（32）与相对的第二配合表面（35）配合，以在其间基本上径向地包围支架（11），并且基本上防止了放射性同位素的直接通过 所述支架从所述屏蔽组件（30）中径向伸出。
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10.发明授权
公开(公告)号：US5800494A
公开(公告)日：1998-09-01
申请号：US700291
申请日：1996-08-20
申请人： Thomas H. Campbell , Peter Sturzu
发明人： Thomas H. Campbell , Peter Sturzu
CPC分类号： A61B18/18 , A61B18/1815 , A61N1/403 , A61B2018/1861
摘要： A variety of improved antenna arrangements for ablation catheters and methods for constructing catheter with these antenna arrangements are described. In various apparatus aspects of the invention, the catheter includes an elongated flexible tubular member adapted to be inserted into a vessel in the body of a patient. A transmission line suitable for transmitting electromagnetic energy is received within the tubular member. An antenna is coupled to the transmission line for generating an electric field sufficiently strong to cause tissue ablation. In one embodiment, the antenna takes the form of an antenna coil that is oriented such that its longitudinal axis extends substantially perpendicular to the longitudinal axis of the flexible tubular member. In another embodiment, a plurality of such laterally oriented antenna coils are provided at longitudinally spaced locations relative to the catheter axis. In other embodiments, the antenna coil is spirally wound. A variety of spiral antenna arrangements are contemplated. In some embodiments, the coil is wound in a substantially conical or frusto-conical manner expanding either distally or proximately. In still another embodiment, the antenna coil is wound in a substantially flat coil.
摘要翻译： 描述了用于消融导管的各种改进的天线布置以及用这些天线装置构造导管的方法。 在本发明的各种装置方面，导管包括适于插入患者体内的容器中的细长柔性管状构件。 适于传输电磁能的传输线被接收在管状构件内。 天线耦合到传输线，用于产生足够强的电场以引起组织消融。 在一个实施例中，天线采用天线线圈的形式，其被定向成使得其纵向轴线基本上垂直于柔性管状构件的纵向轴线延伸。 在另一个实施例中，多个这样的横向定向的天线线圈相对于导管轴线在纵向间隔开的位置处设置。 在其它实施例中，天线线圈螺旋缠绕。 预期各种螺旋天线布置。 在一些实施例中，线圈以基本上圆锥形或截头圆锥形的方式缠绕，其向远侧或近端扩展。 在另一个实施例中，天线线圈缠绕在基本平坦的线圈中。
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