摘要:
The present invention provides a method for the measurement of an analyte in biological samples whereby an uncompetitive inhibitor is coupled to a ligand and utilized in a homogeneous assay. The analyte can be a drug or drug derivative, hormone, polypeptide, or oligonucleotide.The present invention also provides novel compounds, assay reagents and packaged kits useful for performing such measurements.
摘要:
The present invention provides a method for the measurement of an analyte in biological samples whereby an uncompetitive inhibitor is coupled to a ligand and utilized in a homogeneous assay. The analyte can be a drug or drug derivative, hormone, polypeptide, or oligonucleotide.The present invention also provides novel compounds, assay reagents and packaged kits useful for performing such measurements.
摘要:
The present invention provides a method for the measurement of an analyte in biological samples whereby an uncompetitive inhibitor is coupled to a ligand and utilized in a homogeneous assay. The analyte can be a drug or drug derivative, hormone, polypeptide, or oligonucleotide. The present invention also provides novel compounds, assay reagents and packaged kits useful for performing such measurements.
摘要:
The present invention provides a method for the measurement of an analyte in biological samples whereby an uncompetitive inhibitor is coupled to a ligand and utilized in a homogeneous assay. The analyte can be a drug or drug derivative, hormone, polypeptide, or oligonucleotide. The present invention also provides novel compounds, assay reagents and packaged kits useful for performing such measurements.
摘要:
The present invention provides a method for the measurement of an analyte in biological samples whereby an uncompetitive inhibitor is coupled to a ligand and utilized in a homogeneous assay. The analyte can be a drug or drug derivative, hormone, polypeptide, or oligonucleotide. The present invention also provides novel compounds, assay reagents and packaged kits useful for performing such measurements.
摘要:
The present invention extends the truck bed, thus increasing cargo space by the length of the truck tailgate. One embodiment of the invention comprises rotatably attaching an end panel to the tailgate, with rotatable and storable support members. Another embodiment comprises right and left side panels rotatably attached to the end panel. When the assembly is stored, either the support members or the side panels are rotated inward to rest against the inner surface of the end panel and the end panel is rotated downwardly and secured against the upper surface of the tailgate. When the assembly is deployed, the end panel is unsecured from the tailgate and is rotated upwardly until approximately perpendicular with the tailgate and the cargo space bed. The support members or side panels are rotated outwardly and secured to complete deployment. In certain embodiments, the end panel may be removed easily and quickly, or lowered down and out of the way, to allow and facilitate loading of longer items in the cargo space, and then reattached and deployed. The mounting bracket and/or end panel may comprise molded reinforced plastic composite material.
摘要:
The present invention discloses compounds corresponding to formula I: wherein A, Z, Z1, Y, R1 and R2 are as defined in the specification, as well as pharmaceutical formulations, methods of making and uses thereof.
摘要:
Compounds, compositions and methods that are useful in the treatment of inflammatory, immunoregulatory, metabolic and cell proliferative conditions or diseases are provided herein. In particular, the invention provides compounds which modulate the expression and/or function of proteins involved in inflammation, metabolism and cell proliferation. The subject compounds contain fused carbocyclic or heterocyclic rings.
摘要:
The present invention comprises various embodiments of a rack that is adapted for the bed of a pickup truck for securing ramps, ladders and the like. The rack comprises two spaced apart vertical support members. Each vertical support member comprises two spaced apart U-support assemblies. Each of the resulting four U-support assemblies are independently and slidably adjustable relative to the other U-support assemblies. In the preferred embodiment, the slidable adjustment capabilities of the U-support assemblies comprises infinite adjustability. Thus, the present invention allows for securing ramps, ladders and the like having varying widths.
摘要:
Compounds, compositions and methods that are useful in the treatment of inflammatory, immunoregulatory, metabolic and cell proliferative conditions or diseases are provided herein. In particular, the invention provides compounds which modulate the expression and/or function of proteins involved in inflammation, metabolism and cell proliferation. The subject compounds contain fused carbocyclic or heterocyclic rings.