公开(公告)号：US06773997B2

公开(公告)日：2004-08-10

申请号：US09917731

申请日：2001-07-31

申请人： Mohamed Imam ,  Joe Fulton ,  Zia Hossain ,  Masami Tanaka ,  Taku Yamamoto ,  Yoshio Enosawa ,  Katsuya Yamazaki ,  Evgueniy Stefanov

发明人： Mohamed Imam ,  Joe Fulton ,  Zia Hossain ,  Masami Tanaka ,  Taku Yamamoto ,  Yoshio Enosawa ,  Katsuya Yamazaki ,  Evgueniy Stefanov

IPC分类号： H01L21336

CPC分类号： H01L29/0847 ,  H01L29/0634 ,  H01L29/0878 ,  H01L29/402 ,  H01L29/42368 ,  H01L29/7835

摘要： A high voltage MOSFET device (100) has an nwell region (113) with a p-top layer (108) of opposite conductivity formed to enhance device characteristics. The p-top layer is implanted through a thin gate oxide, and is being diffused into the silicon later in the process using the source/drain anneal process. There is no field oxide grown on the top of the extended drain region, except two islands of field oxide close to the source and drain diffusion regions. This eliminates any possibility of p-top to be consumed by the field oxide, and allows to have a shallow p-top with very controlled and predictable p-top for achieving low on-resistance with maintaining desired breakdown voltage.

摘要翻译： 高电压MOSFET器件（100）具有形成有相反导电性的p顶层（108）的n阱区域（113），以增强器件特性。 p顶层通过薄栅极氧化物注入，并且在使用源极/漏极退火工艺的工艺中稍后扩散到硅中。 在扩展漏极区域的顶部没有生长场氧化物，除了靠近源极和漏极扩散区域的场氧化物的两个岛外。 这消除了由场氧化物消耗p-top的任何可能性，并且允许具有非常受控和可预测的p-top的浅p顶，用于实现低导通电阻，同时保持所需的击穿电压。

公开(公告)号：US06492679B1

公开(公告)日：2002-12-10

申请号：US09920655

申请日：2001-08-03

申请人： Mohamed Imam ,  Joe Fulton ,  Zia Hossain ,  Masami Tanaka ,  Taku Yamamoto ,  Yoshio Enosawa ,  Katsuya Yamazaki ,  Evgueniy N. Stefanov

发明人： Mohamed Imam ,  Joe Fulton ,  Zia Hossain ,  Masami Tanaka ,  Taku Yamamoto ,  Yoshio Enosawa ,  Katsuya Yamazaki ,  Evgueniy N. Stefanov

IPC分类号： H01L2976

CPC分类号： H01L29/0847 ,  H01L29/0634 ,  H01L29/402 ,  H01L29/41725 ,  H01L29/42368 ,  H01L29/7835

摘要： A high voltage MOSFET device (100) has a well region (113) with two areas. The first area (110) has a high dopant concentration and the second area (112) has a low dopant concentration. Inside the well region a region of a secondary conductivity type (108) is formed. The second area (110) is typically underlying a gate region (105). The lower doping concentration in that area helps to increase the breakdown voltage when the semiconductor device is blocking voltage and helps to decrease the on-resistance when the semiconductor device is in the “on” state. The MOSFET device further has a p-top layer (108) which is disposed on the top surface of the well region and then driven into the well region by annealing the MOSFET device at a high temperature in an inert atmosphere.

摘要翻译： 高电压MOSFET器件（100）具有带有两个区域的阱区（113）。 第一区域（110）具有高掺杂剂浓度，第二区域（112）具有低掺杂剂浓度。 在阱区内形成二次导电型（108）的区域。 第二区域（110）通常位于栅极区域（105）下方。 当半导体器件处于“导通”状态时，该半导体器件阻挡电压并有助于降低导通电阻，该区域中较低的掺杂浓度有助于提高击穿电压。 MOSFET器件还具有p顶层（108），其设置在阱区的顶表面上，然后通过在惰性气氛中的高温退火MOSFET器件而被驱动进入阱区。

公开(公告)号：US09169520B2

公开(公告)日：2015-10-27

申请号：US14039835

申请日：2013-09-27

申请人： Masahiko Kuroda ,  Masami Tanaka ,  Kosuke Oikawa ,  Takayuki Mizutani ,  Masakatsu Takanashi ,  Seiko Iizuka ,  Yoshinori Kosugi ,  Kazuma Ohyashiki ,  Akihiko Tsuchida

发明人： Masahiko Kuroda ,  Masami Tanaka ,  Kosuke Oikawa ,  Takayuki Mizutani ,  Masakatsu Takanashi ,  Seiko Iizuka ,  Yoshinori Kosugi ,  Kazuma Ohyashiki ,  Akihiko Tsuchida

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6886 ,  C12Q2600/158 ,  C12Q2600/178

摘要： The present invention provides a novel cancer marker for evaluating the onset, the preclinical stage, the clinical stage, or the prognosis of a cancer in a subject, and an evaluation method using the same. A cancer marker containing at least one miRNA selected from hsa-miR-92 and hsa-miR-494 is used as a marker for cancers excluding breast cancer. A method for evaluating the possibility of cancers excluding breast cancer includes the step of detecting the expression level of a cancer marker in a biological sample collected from a subject. In this method, the cancer marker contains at least one miRNA selected from hsa-miR-92 and hsa-miR-494.

摘要翻译： 本发明提供了用于评估受试者的癌症的发病，临床前期，临床阶段或预后的新型癌症标志物及其评价方法。 使用含有至少一种选自hsa-miR-92和hsa-miR-494的miRNA的癌症标记物作为不包括乳腺癌的癌症的标志物。 用于评估除乳腺癌之外的癌症的可能性的方法包括检测从受试者收集的生物样品中癌症标志物的表达水平的步骤。 在该方法中，癌标记物含有至少一种选自hsa-miR-92和hsa-miR-494的miRNA。

公开(公告)号：US08800873B2

公开(公告)日：2014-08-12

申请号：US11812686

申请日：2007-06-21

申请人： Masami Tanaka ,  Kunihiko Ito ,  Manabu Miyazaki ,  Hiroshi Ota ,  Koji Konosu

发明人： Masami Tanaka ,  Kunihiko Ito ,  Manabu Miyazaki ,  Hiroshi Ota ,  Koji Konosu

IPC分类号： G06K7/10 ,  G06K9/36 ,  G06K9/80 ,  G06K5/04 ,  G06K9/00 ,  G06K9/22 ,  G06K19/06 ,  G06K19/08 ,  G06K21/00 ,  G06K7/14

CPC分类号： G06K7/10722 ,  G06K7/1417 ,  G06K7/1473

摘要： In an apparatus for optically reading a graphic symbol composed of a plurality of optically identifiable unit sections of information, a first image pickup unit has a first photodetector and picks up a first optical image of the graphic symbol based on light detected by the first photodetector. A second image pickup unit has a second photodetector and configured to pick up a second optical image of the graphic symbol based on light detected by the second photodetector. A correcting unit corrects a light intensity level of at least one section of one of the first and second optical images based on a light intensity level of at least one section of the other of the first and second optical images. The at least one section corresponds to at least one of the unit sections of information of the graphic symbol.

摘要翻译： 在用于光学读取由多个可光学识别的单元部分信息组成的图形符号的装置中，第一图像拾取单元具有第一光电检测器，并且基于由第一光电检测器检测到的光拾取图形符号的第一光学图像。 第二图像拾取单元具有第二光电检测器，并且被配置为基于由第二光电检测器检测到的光拾取图形符号的第二光学图像。 校正单元基于第一和第二光学图像中的另一个的至少一个部分的光强度级别校正第一和第二光学图像中的一个的至少一个部分的光强度水平。 至少一个部分对应于图形符号的信息的单元部分中的至少一个。

公开(公告)号：US08235303B2

公开(公告)日：2012-08-07

申请号：US12382872

申请日：2009-03-26

申请人： Hiroaki Mizukoshi ,  Masami Tanaka ,  Yuichi Ito ,  Hayato Kita ,  Takao Ushijima ,  Masahiro Hara

发明人： Hiroaki Mizukoshi ,  Masami Tanaka ,  Yuichi Ito ,  Hayato Kita ,  Takao Ushijima ,  Masahiro Hara

IPC分类号： G06K19/06

CPC分类号： G06K19/06037 ,  G06K19/06046 ,  G06K19/06075

摘要： A two-dimensional code having a rectangular region is provided. In the rectangular region, there are code blocks composed of a plurality of cells, a first specific pattern specifying the positions of the cells, and a second specific pattern separating the code blocks from a background of the code. The first specific pattern is located at a specified corner of the rectangular region. The second specific pattern is located along one or more of first borders along which the first specific pattern is located, the first borders being part of the borders of the rectangular region. The code blocks include error-correction code blocks, which are located along second borders which are different from a border of the borders along which the second specific pattern is located. The second borders are part of the borders. Compressed data code blocks are also arranged in the same way as the error-correction code blocks.

摘要翻译： 提供具有矩形区域的二维码。 在矩形区域中，存在由多个单元组成的代码块，指定单元的位置的第一特定模式以及将代码块与代码的背景区分开的第二特定模式。 第一个特定图案位于矩形区域的指定拐角处。 第二特定图案沿着第一特定图案所位于的第一边界沿着一个或多个第一边界定位，第一边界是矩形区域的边界的一部分。 代码块包括纠错码块，它们沿着与第二特定模式所位于的边界的边界不同的第二边界定位。 第二个边界是边界的一部分。 压缩数据代码块也以与纠错码块相同的方式排列。

公开(公告)号：US20110028332A1

公开(公告)日：2011-02-03

申请号：US12934948

申请日：2009-03-27

申请人： Masahiko Kuroda ,  Masami Tanaka ,  Kosuke Oikawa ,  Takayuki Mizutani ,  Masakatsu Takanashi

发明人： Masahiko Kuroda ,  Masami Tanaka ,  Kosuke Oikawa ,  Takayuki Mizutani ,  Masakatsu Takanashi

IPC分类号： C40B30/00 ,  C07H21/02 ,  C40B40/06

CPC分类号： C12Q1/6886 ,  C12Q2600/112 ,  C12Q2600/158 ,  C12Q2600/178

摘要： An embodiment of the present invention provides a marker, a test method, and a test kit which can detect the onset of breast cancer that cannot be detected by palpation or mammography examination or breast cancer in an early stage (clinical stage 0), which are simple, and which have high reliability.A marker associated with breast cancer of an embodiment of the present invention is characterized by being a micro-RNA that is found in serum or plasma. More specifically, the marker contains at least a micro-RNA that is present in the serum or the plasma at a significantly reduced level after the onset of breast cancer, or during or after an early stage (during or after clinical stage 0) of breast cancer compared with that before the onset of breast cancer or before the early stage (before clinical stage 0) of breast cancer.

摘要翻译： 本发明的一个实施方案提供了可以检测在早期阶段（临床阶段0）不能通过触诊或乳房X线照相检查或乳腺癌检测到的乳腺癌发作的标志物，测试方法和测试试剂盒，其为 简单，可靠性高。 与本发明实施方案的乳腺癌相关的标志物的特征在于是在血清或血浆中发现的微RNA。 更具体地，标记物在乳腺癌发作后或在乳腺早期（临床阶段0期间或之后）期间或之后存在于血清或血浆中存在的至少一种微RNA，其显着降低水平 与乳腺癌发病前或乳腺癌早期（临床阶段0之前）癌症相比较。

公开(公告)号：US20090289959A1

公开(公告)日：2009-11-26

申请号：US11887648

申请日：2006-03-16

申请人： Masami Tanaka ,  Kazuyoshi Nishi

发明人： Masami Tanaka ,  Kazuyoshi Nishi

IPC分类号： G09G5/10 ,  G09G3/36

CPC分类号： G09G3/3688 ,  G09G3/2011 ,  G09G3/3648 ,  G09G3/3696 ,  G09G2300/0417 ,  G09G2300/08 ,  G09G2310/0248 ,  G09G2310/027 ,  G09G2310/0297 ,  G09G2320/0209 ,  G09G2320/0214

摘要： A selector (103A) outputs a gray level voltage corresponding to pixel data (D-A) as drive voltage (Va). When the drive voltage (Va) is written in a source line (LineS-A), switches (105A-1, 105A-2) are ON while a switch (106A) is OFF. When the drive voltage (Va) written in the source line (LineS-A) is retained, the switches (105A-1,105A-2) are OFF while the switch (106A) is ON.

摘要翻译： 选择器（103A）输出与像素数据（D-A）相对应的灰度级电压作为驱动电压（Va）。 当驱动电压（Va）被写入源极线（LineS-A）时，开关（106A）为OFF时，开关（105A-1,10AA-2）为ON。 当保持写入源极线（LineS-A）的驱动电压（Va）时，开关（106A）接通时开关（105A-1,105A-2）为OFF。

公开(公告)号：US07268539B2

公开(公告)日：2007-09-11

申请号：US11541148

申请日：2006-09-28

申请人： Kensaku Sato ,  Masami Tanaka ,  Tadashi Kubota ,  Hideki Sakamoto ,  Makoto Kobayashi ,  Satoshi Yamaguchi ,  Mamoru Hasegawa ,  Yuichi Shimasaki

发明人： Kensaku Sato ,  Masami Tanaka ,  Tadashi Kubota ,  Hideki Sakamoto ,  Makoto Kobayashi ,  Satoshi Yamaguchi ,  Mamoru Hasegawa ,  Yuichi Shimasaki

IPC分类号： G01B7/30

CPC分类号： G01D5/147

摘要： A pulse signal generator using a magnetic device that can cause a large Barkhausen effect, comprises means having a number of pits and projections and generates pulses according to the behavior of these, the means being capable of moving the pits and projections in a first or second direction, the pits and projections being disposed in the moving direction with some of the projections missing or some of the pits filled. The value of the ratio between the time interval of pulses generated by portions other than a projection-missing portion and the time interval of pulses generated by the projection-missing portion or the value of the ratio between the time interval of pulses generated by portions other than a pit-filled portion and the time interval of pulses generated by the pit-filled portion differs between when the pits and projections move in the first or second direction.

摘要翻译： 使用可引起大的巴克豪森效应的磁性装置的脉冲信号发生器包括具有多个凹坑和突起的装置，并且根据这些的行为产生脉冲，该装置能够将凹坑和突起移动到第一或第二 方向，凹坑和突起沿着移动方向设置，其中一些突起丢失或一些凹坑被填充。 由投射缺失部分以外的部分产生的脉冲的时间间隔与由投影缺失部分产生的脉冲的时间间隔之间的比率的值或由其他部分产生的脉冲的时间间隔之间的比率的值之间的值 并且由凹坑填充部分产生的脉冲的时间间隔在凹坑和突起在第一或第二方向上移动时不同。

公开(公告)号：US20070004932A1

公开(公告)日：2007-01-04

申请号：US11517457

申请日：2006-09-08

申请人： Mikio Yamahiro ,  Hisao Oikawa ,  Kenya Ito ,  Masami Tanaka ,  Nobumasa Ootake ,  Kenichi Watanabe

发明人： Mikio Yamahiro ,  Hisao Oikawa ,  Kenya Ito ,  Masami Tanaka ,  Nobumasa Ootake ,  Kenichi Watanabe

IPC分类号： C07F7/04 ,  C07F7/08

CPC分类号： C07F7/21 ,  C07F7/0876

摘要： The object of the present invention is to provide a new kind of silicon compound having an ester-type organic functional group and a new method for providing a T8-silsesquioxane compound having a hydroxyl group by using said silicon compound as the starting material. A silicon compound represented by formula (1) is obtained through the production process characterized by using a silicon compound represented by formula (2). wherein: in formula (1), each of seven R1 group is independently selected from the group consisting of hydrogen, alkyl, substituted or unsubstituted aryl, and substituted or unsubstituted arylalkyl and A2 is a hydroxyl-terminal organic functional group, and in formula (2), each of R1 group is the same as R1 in formula (1), and A1 is an organic functional group containing an acyloxy group.

摘要翻译： 本发明的目的是提供一种具有酯型有机官能团的新型硅化合物和通过使用所述硅来提供具有羟基的T 8 -S-倍半硅氧烷化合物的新方法 化合物作为原料。 通过以式（2）表示的硅化合物为特征的制造方法得到式（1）所示的硅化合物。 其中：在式（1）中，七个R 1基团中的每一个独立地选自氢，烷基，取代或未取代的芳基和取代或未取代的芳基烷基和A 2， / SUP>是羟基末端有机官能团，并且在式（2）中，R 1和R 2各自与式（1）中的R 1相同， A 1是含有酰氧基的有机官能团。

公开(公告)号：US07129370B2

公开(公告)日：2006-10-31

申请号：US10664151

申请日：2003-09-17

申请人： Mikio Yamahiro ,  Hisao Oikawa ,  Kenya Ito ,  Masami Tanaka ,  Nobumasa Ootake ,  Kenichi Watanabe

发明人： Mikio Yamahiro ,  Hisao Oikawa ,  Kenya Ito ,  Masami Tanaka ,  Nobumasa Ootake ,  Kenichi Watanabe

IPC分类号： C07F7/04

CPC分类号： C07F7/21 ,  C07F7/0876

摘要： The object of the present invention is to provide a new kind of silicon compound having an ester-type organic functional group and a new method for providing a T8-silsesquioxane compound having a hydroxyl group by using said silicon compound as the starting material.A silicon compound represented by formula (1) is obtained through the production process characterized by using a silicon compound represented by formula (2). wherein: in formula (1), each of seven R1 group is independently selected from the group consisting of hydrogen, alkyl, substituted or unsubstituted aryl, and substituted or unsubstituted arylalkyl and A2 is a hydroxyl-terminal organic functional group, and in formula (2), each of R1 group is the same as R1 in formula (1), and A1 is an organic functional group containing an acyloxy group.

摘要翻译： 本发明的目的是提供一种具有酯型有机官能团的新型硅化合物和通过使用所述硅来提供具有羟基的T 8 -S-倍半硅氧烷化合物的新方法 化合物作为原料。 通过以式（2）表示的硅化合物为特征的制造方法得到式（1）所示的硅化合物。 其中：在式（1）中，七个R 1基团中的每一个独立地选自氢，烷基，取代或未取代的芳基和取代或未取代的芳基烷基和A 2， / SUP>是羟基末端有机官能团，并且在式（2）中，R 1和R 2各自与式（1）中的R 1相同， A 1是含有酰氧基的有机官能团。