公开(公告)号：US10035749B2

公开(公告)日：2018-07-31

申请号：US14915554

申请日：2014-09-03

Applicant: MYRIANT CORPORATION

Inventor： Vijay Gnanadesikan ,  Ramnik Singh ,  Rajesh Dasari ,  Montgomery Alger

IPC: C07C51/27 ,  C07C29/60 ,  C07C51/285 ,  C07C209/16 ,  C07C253/26 ,  C07C29/44 ,  C07C51/16

CPC classification number: C07C51/27 ,  C07C29/44 ,  C07C29/60 ,  C07C51/16 ,  C07C51/285 ,  C07C209/16 ,  C07C253/26 ,  C07C33/03 ,  C07C255/08 ,  C07C211/21 ,  C07C57/04

Abstract: The present invention is in the field of producing bio-based commodity organic chemicals such as bio-acrylic acid, bio-acrylonitrile, and bio-1,4-butanediol using renewable carbon sources as feedstock. In the first stage of the present invention, bio-1,3-propanediol is derived from renewable carbon sources through microbial fermentation. In the second stage of the present invention, bio-1,3-propanediol is converted into bio-acrylic acid or bio-acrylonitrile or bio-1,4-butanediol.

公开(公告)号：US20150038735A1

公开(公告)日：2015-02-05

申请号：US14383553

申请日：2013-09-06

Applicant: MYRIANT CORPORATION

Inventor： Cenan A. Ozmeral ,  Joseph P. Glas ,  Rajesh Dasari ,  Setrak Tanielyan ,  Ramesh Deoram Bhagat ,  Mohan Reddy Kasireddy ,  Ramnik Singh ,  Vijay Gnanadesikan ,  Robert L. Augustine ,  Santosh More

IPC: C07C67/327 ,  C07C51/377

CPC classification number: C07C67/327 ,  C07C51/09 ,  C07C51/377 ,  C07C57/04 ,  C07C69/54

Abstract: An L-type zeolite, a modified L-type zeolite, or any combination thereof may be useful in catalytically preparing α,β-unsaturated carboxylic acids and/or esters thereof through reaction pathways that include dehydroxylation reactions and optionally esterification reactions. In some reaction pathways, dehydroxylation reactions and esterification reactions may be performed sequentially or concurrently.

Abstract translation: L型沸石，改性L型沸石或其任何组合可用于通过包括脱羟基反应和任选的酯化反应的反应途径催化制备α，β-不饱和羧酸和/或其酯。 在一些反应途径中，可以顺序地或同时地进行脱羟基化反应和酯化反应。

公开(公告)号：US20180134647A1

公开(公告)日：2018-05-17

申请号：US15580041

申请日：2016-06-10

Applicant: Myriant Corporation

Inventor： Cenan Ozmeral ,  Rajesh Dasari ,  Ramnik Singh ,  Yu Noda ,  Robert M. Rioux ,  Yuriy Roman-Leshkov

IPC: C07C51/377 ,  B01J29/60 ,  B01J29/08 ,  B01J29/18 ,  B01J29/40 ,  B01J27/18 ,  B01J37/30 ,  B01J37/02

CPC classification number: C07C51/377 ,  B01J27/1806 ,  B01J29/082 ,  B01J29/084 ,  B01J29/18 ,  B01J29/40 ,  B01J29/60 ,  B01J29/7007 ,  B01J35/002 ,  B01J37/0201 ,  B01J37/30 ,  B01J2229/123 ,  B01J2229/183 ,  C07C45/54 ,  Y02P20/588 ,  C07C57/04 ,  C07C47/06

Abstract: Described herein are solid acid catalysts and the methods for catalytically preparing α,β-unsaturated carboxylic acids and/or esters thereof. In one aspect, a zeolite catalyst may be used. The catalyst may, in certain embodiments, be modified to improve the selectivity and/or conversion of a reaction. For instance, a catalyst may be modified by ion exchange to achieve a desirable acidity profile in order to achieve high level of conversion of reactants and selectivity for desirable products of the catalytic reaction. In another aspect, a variety of feed stocks (e.g., starting compositions) may be used including an α-hydroxycarboxylic acid, an α-hydroxycarboxylic acid ester, a β-hydroxycarboxylic acid, a β-hydroxycarboxylic acid ester, cyclic esters thereof (e.g., lactide), and combinations thereof.

公开(公告)号：US20160304912A1

公开(公告)日：2016-10-20

申请号：US15101015

申请日：2014-12-05

Applicant: MYRIANT CORPORATION

Inventor： Thidarat Tosukhowong ,  Bin Wang ,  Manav Mistry ,  Rajesh Dasari ,  Zachary Wilson

IPC: C12P7/62 ,  C07C67/58 ,  C12P7/46 ,  C07C51/02 ,  C07C51/09 ,  C07C67/08 ,  C07C51/43

CPC classification number: C12P7/62 ,  C07C51/02 ,  C07C51/09 ,  C07C51/43 ,  C07C67/08 ,  C07C67/58 ,  C12P7/46 ,  C07C69/40 ,  C07C55/10

Abstract: This invention relates to a process for preparing succinate ester from a succinic acid salt present in a fermentation broth. In the first stage of this invention, renewable carbon resources are utilized to produce succinic acid in the form of a succinic acid salt through biological fermentation. The succinic acid salt present in the fermentation broth is subjected to double displacement reaction with a strong acid leading to the release of succinic acid. Succinic acid is recovered by fractional crystallization integrated with an alcohol washing step and subjected to esterification reaction to produce succinate ester which is purified by fractional distillation. The succinate ester thus obtained is converted into 1,4-butanediol, gamma-butyrolactone and tetrahydrofuran through hydrogenation reactions. The succinate ester can also be hydrolyzed to yield highly pure succinic acid.

Abstract translation: 本发明涉及由存在于发酵液中的琥珀酸盐制备琥珀酸酯的方法。 在本发明的第一阶段，利用可再生碳资源通过生物发酵生产琥珀酸盐形式的琥珀酸。 存在于发酵液中的琥珀酸盐与强酸进行双位置反应，导致琥珀酸的释放。 通过与醇洗涤步骤一体化的分级结晶回收琥珀酸，并进行酯化反应以制备通过分馏纯化的琥珀酸酯。 由此获得的琥珀酸酯通过氢化反应转化成1,4-丁二醇，γ-丁内酯和四氢呋喃。 琥珀酸酯也可以水解，得到高纯度的琥珀酸。