-
公开(公告)号：US10750741B2
公开(公告)日：2020-08-25
申请号：US15792963
申请日：2017-10-25
发明人： Seizo Sato , Takuro Fukae , Naomi Ohtsuka , Hideaki Yamaguchi , Rie Ikeda
IPC分类号： A61K36/06 , A01N37/06 , A61K8/99 , A61K31/202 , C11B1/02 , C11B3/12 , C11C1/00 , A61K8/36 , A61Q19/00 , A23L33/115 , C12N1/28 , C12P7/64 , A23D9/013 , A23D9/02 , C11B3/10 , C11C3/10 , A23K20/158
摘要： A microbial oil comprising dihomo-γ-linolenic acid as a constituent fatty acid of an oil, the microbial oil has a content, in terms of a weight ratio of arachidonic acid relative to dihomo-γ-linolenic acid (arachidonic acid/dihomo-γ-linolenic acid) of less than 1/13. Preferably, the microbial oil has a triglyceride content of greater than or equal to 70% by weight, and a saturated fatty acid content of less than or equal to 40% by weight. Moreover, a lower alcohol ester of dihomo-γ-linolenic acid or a free fatty acid of dihomo-γ-linolenic acid obtained from the microbial oil is provided.
-
公开(公告)号：US10597606B2
公开(公告)日：2020-03-24
申请号：US15393576
申请日：2016-12-29
发明人： Seizo Sato , Takuro Fukae , Naomi Ohtsuka , Hideaki Yamaguchi
IPC分类号： C11C1/04 , C11C1/10 , C11C3/10 , A23L33/12 , A61K31/201 , A61K31/231 , C11C3/04
摘要： A method for producing monovalent unsaturated free fatty acids having 20 and/or 22 carbons or low-grade alcohol esters thereof, said method involving the following: obtaining free fatty acids or low-grade alcohol esters through the hydrolysis or alcoholysis of oils and fats derived from marine products; carrying out distillation on the free fatty acids or low-grade alcohol esters, and reducing the concentration of fatty acids with 18 or less carbons in the low-grade alcohol esters or free fatty acids; and collecting fractions of monovalent unsaturated free fatty acids having 20 and/or 22 carbons or low-grade alcohol esters thereof by column chromatography based on reversed-phase distribution.
-
3.发明申请公开(公告)号：US20190015375A1
公开(公告)日：2019-01-17
申请号：US16134140
申请日：2018-09-18
发明人： Nobushige Doisaki , Shingo Arato , Takuro Fukae
IPC分类号： A61K31/232 , C11C3/10 , C11B3/12 , C07C69/587 , C07C67/54 , C07C67/03 , C07C67/56
CPC分类号： A61K31/232 , C07C67/03 , C07C67/54 , C07C67/56 , C07C69/587 , C11B3/12 , C11C3/10
摘要： Provided are: a composition containing 96-99 area % of eicosapentaenoic acid alkyl ester, the composition having an arachidonic acid alkyl ester content of 0.7 area % or less, and an eicosapentaenoic-acid-alkyl-ester mono-trans isomer content of 2.5 area % or less; and a method for producing a composition containing a high concentration of eicosapentaenoic acid alkyl ester, the method including performing precision distillation on a composition containing eicosapentaenoic acid alkyl ester, obtained by alkyl esterification of a raw material oil containing eicosapentaenoic acid, under a vacuum of 0.2 Torr or lower and a temperature of 190° C. or lower in the entire column, and performing a concentration treatment on the precision-distilled composition using chromatography.
-
公开(公告)号：US20210030707A1
公开(公告)日：2021-02-04
申请号：US17076090
申请日：2020-10-21
发明人： Nobushige Doisaki , Shingo Arato , Takuro Fukae
IPC分类号： A61K31/232 , C07C67/03 , C07C67/54 , C07C67/56 , C07C69/587 , C11B3/12 , C11C3/10
摘要： Provided are: a composition containing 96-99 area % of eicosapentaenoic acid alkyl ester, the composition having an arachidonic acid alkyl ester content of 0.7 area % or less, and an eicosapentaenoic-acid-alkyl-ester mono-trans isomer content of 2.5 area % or less; and a method for producing a composition containing a high concentration of eicosapentaenoic acid alkyl ester, the method including performing precision distillation on a composition containing eicosapentaenoic acid alkyl ester, obtained by alkyl esterification of a raw material oil containing eicosapentaenoic acid, under a vacuum of 0.2 Torr or lower and a temperature of 190° C. or lower in the entire column, and performing a concentration treatment on the precision-distilled composition using chromatography.
-
公开(公告)号：US10576053B2
公开(公告)日：2020-03-03
申请号：US16134140
申请日：2018-09-18
发明人： Nobushige Doisaki , Shingo Arato , Takuro Fukae
IPC分类号： A61K31/20 , A61K31/232 , C07C67/03 , C07C67/54 , C07C67/56 , C07C69/587 , C11B3/12 , C11C3/10
摘要： Provided are: a composition containing 96-99 area % of eicosapentaenoic acid alkyl ester, the composition having an arachidonic acid alkyl ester content of 0.7 area % or less, and an eicosapentaenoic-acid-alkyl-ester mono-trans isomer content of 2.5 area % or less; and a method for producing a composition containing a high concentration of eicosapentaenoic acid alkyl ester, the method including performing precision distillation on a composition containing eicosapentaenoic acid alkyl ester, obtained by alkyl esterification of a raw material oil containing eicosapentaenoic acid, under a vacuum of 0.2 Torr or lower and a temperature of 190° C. or lower in the entire column, and performing a concentration treatment on the precision-distilled composition using chromatography.
-
公开(公告)号：US11648229B2
公开(公告)日：2023-05-16
申请号：US17076090
申请日：2020-10-21
发明人： Nobushige Doisaki , Shingo Arato , Takuro Fukae
IPC分类号： A61K31/20 , A61K31/232 , C07C67/03 , C07C67/54 , C07C67/56 , C07C69/587 , C11B3/12 , C11C3/10
CPC分类号： A61K31/232 , C07C67/03 , C07C67/54 , C07C67/56 , C07C69/587 , C11B3/12 , C11C3/10
摘要： Provided are: a composition containing 96-99 area % of eicosapentaenoic acid alkyl ester, the composition having an arachidonic acid alkyl ester content of 0.7 area % or less, and an eicosapentaenoic-acid-alkyl-ester mono-trans isomer content of 2.5 area % or less; and a method for producing a composition containing a high concentration of eicosapentaenoic acid alkyl ester, the method including performing precision distillation on a composition containing eicosapentaenoic acid alkyl ester, obtained by alkyl esterification of a raw material oil containing eicosapentaenoic acid, under a vacuum of 0.2 Torr or lower and a temperature of 190° C. or lower in the entire column, and performing a concentration treatment on the precision-distilled composition using chromatography.
-
公开(公告)号：US09918953B2
公开(公告)日：2018-03-20
申请号：US15511757
申请日：2015-09-17
发明人： Nobushige Doisaki , Shingo Arato , Takuro Fukae
IPC分类号： A61K31/22 , A61K31/20 , A61K31/232 , C07C67/03 , C07C67/54 , C07C67/56 , C07C69/587 , C11B3/12 , C11C3/10
CPC分类号： A61K31/232 , C07C67/03 , C07C67/54 , C07C67/56 , C07C69/587 , C11B3/12 , C11C3/10
摘要： Provided are: an eicosapentaenoic acid alkyl ester-ontaining composition which comprises 96-99 area % of an eicosapentaenoic acid alkyl ester, wherein the content of an arachidonic acid alkyl ester is 0.7 area % or less, and the content of mono-trans forms of the eicosapentaenoic acid alkyl ester is 2.5 area % or less; a method for producing a high-concentration eicosapentaenoic acid alkyl ester-containing composition, which comprises performing rectification on an eicosapentaenoic acid alkyl ester-containing composition with the degree of vacuum being 0.2 Torr or less and at a whole-column temperature 190° C. or less, and performing a concentration treatment on the rectified composition using chromatography, the eicosapentaenoic acid alkyl ester-containing composition being obtained by alkyl esterifying a feed oil containing eicosapentaenoic acid.
-
公开(公告)号：US10105340B2
公开(公告)日：2018-10-23
申请号：US15878827
申请日：2018-01-24
发明人： Nobushige Doisaki , Shingo Arato , Takuro Fukae
IPC分类号： A61K31/20 , A61K31/232 , C07C67/54 , C07C67/03 , C11B3/12 , C07C67/56 , C11C3/10 , C07C69/587
摘要： Provided are: a composition containing 96-99 area % of eicosapentaenoic acid alkyl ester, the composition having an arachidonic acid alkyl ester content of 0.7 area % or less, and an eicosapentaenoic-acid-alkyl-ester mono-trans isomer content of 2.5 area % or less; and a method for producing a composition containing a high concentration of eicosapentaenoic acid alkyl ester, the method including performing precision distillation on a composition containing eicosapentaenoic acid alkyl ester, obtained by alkyl esterification of a raw material oil containing eicosapentaenoic acid, under a vacuum of 0.2 Ton or lower and a temperature of 190° C. or lower in the entire column, and performing a concentration treatment on the precision-distilled composition using chromatography.
-
公开(公告)号：US09820484B2
公开(公告)日：2017-11-21
申请号：US15101581
申请日：2014-12-04
发明人： Seizo Sato , Takuro Fukae , Naomi Ohtsuka , Hideaki Yamaguchi , Rie Ikeda
IPC分类号： A01N37/06 , A61K8/99 , A61K31/202 , C11B1/02 , C11B3/12 , C11C1/00 , A61K8/36 , A61Q19/00 , C12N1/28 , C12P7/64 , A23D9/013 , A23D9/02 , C11B3/10 , C11C3/10 , A23K20/158 , A23L33/115 , A61K36/06
CPC分类号： A01N37/06 , A23D9/013 , A23D9/02 , A23K20/158 , A23L33/115 , A61K8/361 , A61K8/99 , A61K31/202 , A61K36/06 , A61Q19/00 , C11B1/025 , C11B3/10 , C11B3/12 , C11C1/005 , C11C3/10 , C12N1/28 , C12P7/6427 , C12P7/6436 , C12P7/6463
摘要： A microbial oil comprising dihomo-γ-linolenic acid as a constituent fatty acid of an oil, the microbial oil has a content, in terms of a weight ratio of arachidonic acid relative to dihomo-γ-linolenic acid (arachidonic acid/dihomo-γ-linolenic acid) of less than 1/13. Preferably, the microbial oil has a triglyceride content of greater than or equal to 70% by weight, and a saturated fatty acid content of less than or equal to 40% by weight. Moreover, a lower alcohol ester of dihomo-γ-linolenic acid or a free fatty acid of dihomo-γ-linolenic acid obtained from the microbial oil is provided.
-
-
-
-
-
-
-
-
搜索结果
9 条记录 (耗时 0.015 秒)
