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    Surface-Enhanced Spectroscopy with Implanted Biosensors
    3.
    发明申请
    Surface-Enhanced Spectroscopy with Implanted Biosensors 审中-公开
    表面增强光谱与植入生物传感器

    公开(公告)号：US20080214913A1

    公开(公告)日：2008-09-04

    申请号：US11816534

    申请日：2006-02-16

    申请人： Antonius Theodorus, Martinus Van Gogh ,  Gert 'T Hooft ,  Gerhardus Wilhelmus Lucassen

    发明人： Antonius Theodorus, Martinus Van Gogh ,  Gert 'T Hooft ,  Gerhardus Wilhelmus Lucassen

    IPC分类号： A61B5/1455 ,  A61B5/00

    CPC分类号： A61B5/14532 ,  A61B5/0059 ,  A61B5/061 ,  A61B5/064 ,  A61B5/1459 ,  G01N21/658

    摘要： The present invention provides a spectroscopic apparatus, a method and a computer program product for determining the concentration of an analyte of a fluid that flows through a capillary vessel of a biological sample. The spectroscopic apparatus makes use of an imaging system for determining the position of at least one biosensing substrate that has been implanted into the biological sample in the proximity of the capillary vessel but outside the capillary vessel. The biosensing substrate is capable of inducing surface-enhanced spectroscopic effects and is preferably adapted to reversibly and selectively bind a certain analyte or molecule of the fluid, to which the vessel wall of the capillary vessel is at least semi-permeable. By performing a spectroscopic analysis not directly inside the capillary vessel but in close proximity to the capillary vessel, the signal-to-noise ratio of the spectroscopic signals obtained can be appreciably enhanced while disadvantageous scattering and interference effects can be minimized.

    摘要翻译： 本发明提供一种用于确定流过生物样品的毛细血管的流体的分析物的浓度的光谱仪，方法和计算机程序产品。 分光装置利用成像系统来确定在毛细血管附近但在毛细血管附近植入生物样品中的至少一个生物传感基片的位置。 生物传感底物能够诱导表面增强的光谱效应，并且优选地适于可逆地和选择性地结合毛细血管的血管壁至少半透性的某些分析物或流体分子。 通过不是直接在毛细血管内部进行光谱分析，而是靠近毛细血管，所获得的光谱信号的信噪比可以明显增强，而不利的散射和干涉效应可以最小化。

    Optical Device, in Particular Holographic Device
    4.
    发明申请
    Optical Device, in Particular Holographic Device 审中-公开
    光学装置，特别是全息装置

    公开(公告)号：US20080130462A1

    公开(公告)日：2008-06-05

    申请号：US11814006

    申请日：2006-01-06

    申请人： Frank Jeroen Pieter Schuurmans ,  Gert 'T Hooft ,  Marcello Leonardo Mario Balistreri

    发明人： Frank Jeroen Pieter Schuurmans ,  Gert 'T Hooft ,  Marcello Leonardo Mario Balistreri

    IPC分类号： G11B7/0065

    CPC分类号： G11B7/1353 ,  G11B7/0065 ,  G11B7/128

    摘要： An optical device comprises a light source (301) for generating a radiation beam, a reflective diffractive structure (304) for reflecting and diffracting said radiation beam along an optical path (PP), imaging means (305) for imaging the radiation beam after it has been reflected and diffracted by said reflective diffractive structure, and a holographic beam splitter (303) between said reflective diffractive structure and said imaging means along said optical path. Such an optical device can be used for recording data into a holographic medium.

    摘要翻译： 光学装置包括用于产生辐射束的光源（301），用于沿着光路（PP）反射和衍射所述辐射束的反射衍射结构（304），用于对其辐射束进行成像的成像装置（305） 已经被所述反射衍射结构反射和衍射，以及沿着所述光路在所述反射衍射结构和所述成像装置之间的全息分束器（303）。 这种光学装置可用于将数据记录到全息介质中。

    Method and device for imaging an interior of a turbid medium using an amplification factor selected from an estimate of expected electrical signal strength
    7.
    发明授权
    Method and device for imaging an interior of a turbid medium using an amplification factor selected from an estimate of expected electrical signal strength 有权
    用于使用从预期电信号强度的估计中选择的放大因子对混浊介质的内部进行成像的方法和装置

    公开(公告)号：US07750331B2

    公开(公告)日：2010-07-06

    申请号：US12094634

    申请日：2006-11-21

    申请人： Levinus Pieter Bakker ,  Gert 'T Hooft ,  Martinus Bernardus Van Der Mark ,  Michael Cornelis Van Beek

    发明人： Levinus Pieter Bakker ,  Gert 'T Hooft ,  Martinus Bernardus Van Der Mark ,  Michael Cornelis Van Beek

    IPC分类号： G01N15/06 ,  G01N21/49 ,  G01N21/85

    CPC分类号： A61B5/4312 ,  A61B5/0091

    摘要： The invention relates to a method and device (1) for imaging an interior of a turbid medium (55). A turbid medium (55) inside a measurement volume (15) is irradiated from a plurality of source positions (25a) with light from a light source (5), and light emanating from the measurement volume (15) is detected from a plurality of detection positions (25b). An image of the interior of the turbid medium (55) is reconstructed from the detected light. In both the method and the device (1), detector signals can be amplified for each source position-detection position pair by a multi-gain amplification unit comprising an amplifier circuit (60). The amplification factor is selected from a number of possible amplification factors based on detected signal strength in the prior art. According to the invention, however, the method and device are adapted such that the amplification factor is selected for at least one source position-detection position pair on the basis of an estimate of expected electrical signal strength.

    摘要翻译： 本发明涉及一种用于对浑浊介质（55）的内部进行成像的方法和装置（1）。 从多个源位置（25a）利用来自光源（5）的光照射测量体积（15）内部的混浊介质（55），并且从测量体积（15）发出的光从多个 检测位置（25b）。 从检测到的光重建混浊介质（55）的内部的图像。 在方法和装置（1）中，通过包括放大器电路（60）的多增益放大单元，可以为每个源位置检测位置对放大检测器信号。 基于现有技术中检测到的信号强度，从多个可能的放大因子中选择放大因子。 然而，根据本发明，所述方法和装置被适配成使得根据预期的电信号强度的估计为至少一个源位置检测位置对选择放大系数。

    System comprising an electronic device and method of operating a system
    9.
    发明申请
    System comprising an electronic device and method of operating a system 审中-公开
    包括电子设备和操作系统的方法的系统

    公开(公告)号：US20070109837A1

    公开(公告)日：2007-05-17

    申请号：US10559056

    申请日：2004-06-02

    申请人： Ralph Kurt ,  Gert 'T Hooft ,  Robert Hendriks

    发明人： Ralph Kurt ,  Gert 'T Hooft ,  Robert Hendriks

    IPC分类号： G11C11/00

    CPC分类号： G02F1/00 ,  G09F9/372

    摘要： A display device is provided in which the electro-optical effect is created through bending of bendable elements, particularly nanowires or nanotubes. Arrays of bendable elements are provided in areas of the display with the light path. This is possible in that the bendable elements are transparent in the case where they are oriented substantially perpendicular to the substrate, but will absorb light if bent at an angle. Hereto, it is of importance that polarized light is used. The bendable elements are preferably separated from the electrodes through a layer of dielectric material, and are bent under the influence of an electric or magnetic field.

    摘要翻译： 提供了一种显示装置，其中通过弯曲可弯曲元件，特别是纳米线或纳米管产生电光效应。 在具有光路的显示器的区域中设置可弯曲元件的阵列。 这是可能的，因为可弯曲元件在它们基本上垂直于基板定向的情况下是透明的，但是如果以一定角度弯曲则吸收光。 至此，使用偏振光是很重要的。 可弯曲元件优选地通过电介质材料与电极分离，并且在电场或磁场的影响下弯曲。

    Optical diffraction element
    10.
    发明申请
    Optical diffraction element 失效
    光学衍射元件

    公开(公告)号：US20060279843A1

    公开(公告)日：2006-12-14

    申请号：US10561861

    申请日：2004-07-05

    申请人： Ralph Kurt ,  Gert 'T Hooft ,  Coen Theodorus Hubertus Liedenbaum ,  Robert Hendriks

    发明人： Ralph Kurt ,  Gert 'T Hooft ,  Coen Theodorus Hubertus Liedenbaum ,  Robert Hendriks

    IPC分类号： G02B27/42

    CPC分类号： B82Y20/00 ,  G02B5/18 ,  G02B5/1847 ,  G02B5/1866 ,  G02B5/3016 ,  G11B7/1353 ,  G11B7/24

    摘要： An optical diffraction element (1) comprises a diffraction layer (4) which is divided into diffraction strips (6) alternating with intermediate strips (8). The diffraction strips comprise nano-elements (10) which are aligned in one direction and absorb radiation (b) which is linearly polarized in this direction. The diffraction element may be a linear or two-dimensional grating (1) or a Fresnel lens (160). The polarization-sensitive grating can be used in optical systems in which only radiation with a specific polarization direction should be diffracted, or in an optical record carrier to allow reading of an information structure with high spatial frequencies.

    摘要翻译： 光学衍射元件（1）包括衍射层（4），其被分成与中间条带（8）交替的衍射条（6）。 衍射条包括在一个方向上排列并吸收沿该方向线性偏振的辐射（b）的纳米元件（10）。 衍射元件可以是线性或二维光栅（1）或菲涅尔透镜（160）。 偏振敏感光栅可以用于其中仅具有特定偏振方向的辐射应该被衍射的光学系统中，或者在光学记录载体中用于允许读取具有高空间频率的信息结构。