Polyvalent multimeric composition containing active polypeptides, pharmaceutical compositions and methods of using the same
    1.
    发明申请
    Polyvalent multimeric composition containing active polypeptides, pharmaceutical compositions and methods of using the same 审中-公开
    含有活性多肽的多价多聚体组合物,药物组合物及其使用方法

    公开(公告)号:US20070053934A1

    公开(公告)日:2007-03-08

    申请号:US11510493

    申请日:2006-08-25

    IPC分类号: A61K31/70 A61K39/12 A01N43/04

    摘要: The invention is directed to compositions comprising polyvalent complexes containing a biocompatible polymer backbone to which is attached a plurality of monomeric anti-microbial peptides and to methods for using such complexes to stabilize anti-microbial peptides for treating or preventing a disease or condition resulting from infection with a microbe. Multivalent derivatives of existing antimicrobial peptides in which several peptides are covalently linked have been investigated. The resulting construct may contain up to 30 or more units, and exhibits a significant enhancement of anti-microbial effect relative to the free peptides: on the order of a ten fold improvement in effectiveness, suggesting that higher multimerization can indeed lead to more effective agents. The invention is also directed to the use of such complexes for delivery of anti-viral peptides, in particular, peptides and peptide fragments obtained from salivary agglutinin protein (gp-340) for use in treating or preventing infection with HIV.

    摘要翻译: 本发明涉及包含含有多个单体抗微生物肽的生物相容性聚合物骨架的多价复合物的组合物,以及使用这些复合物来稳定抗微生物肽以治疗或预防感染引起的疾病或病症的方法 用微生物。 已经研究了几种肽共价连接的现有抗微生物肽的多价衍生物。 所得构建体可以含有多达30个或更多个单元,并且相对于游离肽显示出显着增强的抗微生物效应:有效性提高十倍,这表明更高的多聚化确实会导致更有效的试剂 。 本发明还涉及这种复合物用于递送抗病毒肽,特别是从用于治疗或预防HIV感染的唾液凝集素蛋白(gp-340)获得的肽和肽片段的用途。

    Determining points of interest of a mobile user
    2.
    发明授权
    Determining points of interest of a mobile user 有权
    确定移动用户的兴趣点

    公开(公告)号:US08958822B2

    公开(公告)日:2015-02-17

    申请号:US13269577

    申请日:2011-10-08

    摘要: Methods, systems and apparatus for tracking points of interest of a user of a mobile device are disclosed. One method includes determining points of interest of a user of a mobile device. The method includes obtaining user-related information, wherein the user-related information includes spatial information about the user, and determining at least one point of interest of the user based on the user-related information. Another embodiment includes an apparatus for determining points of interest of a user. For one embodiment, the apparatus is a mobile device. The mobile device is operative to obtain user-related information, wherein the user-related information comprising spatial information about the user, and the mobile device is operative to determine at least one point of interest of the user based on the user-related information.

    摘要翻译: 公开了用于跟踪移动设备的用户的兴趣点的方法,系统和装置。 一种方法包括确定移动设备的用户的兴趣点。 该方法包括获取用户相关信息,其中用户相关信息包括关于用户的空间信息,以及基于用户相关信息确定用户的至少一个兴趣点。 另一实施例包括用于确定用户兴趣点的装置。 对于一个实施例,该设备是移动设备。 移动设备可操作以获得用户相关信息,其中包括关于用户的空间信息的用户相关信息和移动设备可操作以基于用户相关信息来确定用户的至少一个兴趣点。

    FUNCTIONALIZED TISSUE MATRICES
    3.
    发明申请
    FUNCTIONALIZED TISSUE MATRICES 有权
    功能组织矩阵

    公开(公告)号:US20130280223A1

    公开(公告)日:2013-10-24

    申请号:US13865629

    申请日:2013-04-18

    摘要: Disclosed herein are tissue treatment products that have been bound to at least one chelating agent. Also disclosed are tissue treatment products that have been functionalized with at least one metal and/or at least one metal-binding protein. The tissue treatment products can have antimicrobial properties and/or factors that promote or enhance native cell migration, proliferation, and/or revascularization after implantation into a subject. Also disclosed are methods of making and using the tissue treatment products. The tissue treatment products can be implanted into a tissue in need of repair, regeneration, healing, treatment, and/or alteration and can promote or enhance native cell migration, proliferation, and/or revascularization.

    摘要翻译: 本文公开了已结合至少一种螯合剂的组织处理产品。 还公开了已经用至少一种金属和/或至少一种金属结合蛋白官能化的组织处理产品。 组织处理产品可具有在植入受试者之后促进或增强天然细胞迁移,增殖和/或血运重建的抗微生物特性和/或因素。 还公开了制备和使用组织处理产品的方法。 组织处理产品可以植入需要修复,再生,愈合,治疗和/或改变的组织中,并可以促进或增强天然细胞迁移,增殖和/或血运重建。

    IDENTIFY POINTS OF INTEREST USING WIRELESS ACCESS POINTS
    4.
    发明申请
    IDENTIFY POINTS OF INTEREST USING WIRELESS ACCESS POINTS 审中-公开
    使用无线接入点的识别点

    公开(公告)号:US20130267255A1

    公开(公告)日:2013-10-10

    申请号:US13907861

    申请日:2013-06-01

    IPC分类号: H04W4/02

    摘要: Methods, systems and apparatuses for using wireless access points to identify points of interest (POIs), are disclosed. One embodiment includes a method of using wireless access points to identify points of interest (POIs). The method includes collecting wireless access data points, wherein the wireless access data points comprise at least one wireless access point signature of at least one wireless access element of the wireless access points, analyzing the wireless access data points over a time window, comprising identifying segments within the time window, and matching a point of interest (POI) with each identified segment.

    摘要翻译: 公开了使用无线接入点识别兴趣点(POI)的方法,系统和装置。 一个实施例包括使用无线接入点来识别兴趣点(POI)的方法。 该方法包括收集无线接入数据点,其中无线接入数据点包括无线接入点的至少一个无线接入元件的至少一个无线接入点签名,在时间窗口上分析无线接入数据点,包括识别段 在时间窗口内,并将兴趣点(POI)与每个识别的段匹配。

    METHODS AND APPARATUSES FOR FACILITATING GESTURE RECOGNITION
    5.
    发明申请
    METHODS AND APPARATUSES FOR FACILITATING GESTURE RECOGNITION 有权
    用于促进姿势识别的方法和装置

    公开(公告)号:US20120272194A1

    公开(公告)日:2012-10-25

    申请号:US13091901

    申请日:2011-04-21

    IPC分类号: G06F3/033

    摘要: Methods and apparatuses are provided for facilitating gesture recognition. A method may include constructing a matrix based at least in part on an input gesture and a template gesture. The method may further include determining whether a relationship determined based at least in part on the constructed matrix satisfies a predefined threshold. In an instance in which the relationship does not satisfy the predefined threshold, the method may also include eliminating the template gesture from further consideration for recognition of the input gesture. In an instance in which the relationship satisfies the predefined threshold, the method may further include determining a rotation matrix based at least in part on the constructed matrix. Corresponding apparatuses are also provided.

    摘要翻译: 提供了用于促进手势识别的方法和装置。 方法可以包括至少部分地基于输入手势和模板手势构建矩阵。 该方法还可以包括确定至少部分地基于所构造的矩阵确定的关系是否满足预定阈值。 在关系不满足预定义阈值的情况下,该方法还可以包括消除模板手势以进一步考虑以识别输入手势。 在所述关系满足所述预定义阈值的情况下,所述方法还可以包括至少部分地基于所构建的矩阵来确定旋转矩阵。 还提供了相应的装置。

    Determining Points of Interest of a Mobile User
    6.
    发明申请
    Determining Points of Interest of a Mobile User 有权
    确定移动用户的兴趣点

    公开(公告)号:US20120100867A1

    公开(公告)日:2012-04-26

    申请号:US13269577

    申请日:2011-10-08

    IPC分类号: H04W24/00

    摘要: Methods, systems and apparatus for tracking points of interest of a user of a mobile device are disclosed. One method includes determining points of interest of a user of a mobile device. The method includes obtaining user-related information, wherein the user-related information includes spatial information about the user, and determining at least one point of interest of the user based on the user-related information. Another embodiment includes an apparatus for determining points of interest of a user. For one embodiment, the apparatus is a mobile device. The mobile device is operative to obtain user-related information, wherein the user-related information comprising spatial information about the user, and the mobile device is operative to determine at least one point of interest of the user based on the user-related information.

    摘要翻译: 公开了用于跟踪移动设备的用户的兴趣点的方法,系统和装置。 一种方法包括确定移动设备的用户的兴趣点。 该方法包括获取用户相关信息,其中用户相关信息包括关于用户的空间信息,以及基于用户相关信息确定用户的至少一个兴趣点。 另一实施例包括用于确定用户兴趣点的装置。 对于一个实施例,该设备是移动设备。 移动设备可操作以获得用户相关信息,其中包括关于用户的空间信息的用户相关信息和移动设备可操作以基于用户相关信息来确定用户的至少一个兴趣点。

    Apparatus and method for efficiently supporting VoIP in a wireless communication system
    7.
    发明授权
    Apparatus and method for efficiently supporting VoIP in a wireless communication system 有权
    在无线通信系统中有效支持VoIP的装置和方法

    公开(公告)号:US07911945B2

    公开(公告)日:2011-03-22

    申请号:US10918542

    申请日:2004-08-12

    IPC分类号: G08C15/00

    摘要: The present invention concerns methods for efficiently supporting Voice over Internet Protocol (VoIP) on the Forward Packet Data Channel (F-PDCH) in CDMA 2000 1xEV-DV systems. Active speech in VoIP is encoded using, for example enhanced variable rate codec (EVRC), which produces 171, 80 and 16 bits per 20 ms of speech for Rate 1, Rate ½ and Rate ⅛, respectively. However, about 60% of the time a user is inactive during a speech session, so an inordinate amount of system bandwidth is comprised of rate ⅛ VoIP packets. In one embodiment of the present invention the apparatus of the present invention identifies the Rate ⅛ voice frame packets and discards them. In another embodiment of the present invention, the apparatus of the present invention identifies the Rate ⅛ voice frame packets and selects some of them for further transmission. In both embodiments the efficiency of channel utilization is increased since the amount of channel band width used to communicate relatively little information, e.g., gaps of silence, is decreased.

    摘要翻译: 本发明涉及在CDMA 2000 1xEV-DV系统中有效支持前向分组数据信道(F-PDCH)上的因特网协议语音(VoIP)的方法。 VoIP中的活动语音使用例如增强型可变速率编解码器(EVRC)进行编码,其分别为速率1,速率½和速率per分别产生每20毫秒语音的171,80和16比特。 然而,在用户在语音会话期间不活动的时间的大约60%,因此系统带宽的过量由速率⅛VoIP分组组成。 在本发明的一个实施例中,本发明的装置识别速率⅛语音帧分组并丢弃它们。 在本发明的另一实施例中,本发明的装置识别速率⅛语音帧分组,并选择其中一些用于进一步传输。 在两个实施例中,信道利用的效率增加,因为用于传达相对较少的信息的信道带宽的量,例如,沉默的间隙被减少。

    METHOD AND APPARATUS FOR PROVIDING USER INTERACTION VIA TRANSPONDERS
    8.
    发明申请
    METHOD AND APPARATUS FOR PROVIDING USER INTERACTION VIA TRANSPONDERS 有权
    用于通过交付器提供用户交互的方法和装置

    公开(公告)号:US20100271177A1

    公开(公告)日:2010-10-28

    申请号:US12429918

    申请日:2009-04-24

    IPC分类号: H04B7/00

    摘要: An approach is provided for user interaction via transponders (e.g., near field communication (NFC) tag, radio frequency identification (RFID) tag, or contactless card) disposed on a dynamically reconfigurable display. Each transponder corresponds to an area of the display that is associated with one or more actions. The actions are dynamically updated based at least in part on the content presented on the respective area of the display. A user equipment containing a transponder reader detects a signal from one of the transponders to trigger the corresponding action.

    摘要翻译: 提供了一种用于通过设置在动态可重新配置的显示器上的应答器(例如,近场通信(NFC)标签,射频识别(RFID)标签或非接触式卡))进行用户交互的方法。 每个应答器对应于与一个或多个动作相关联的显示器的区域。 至少部分地基于呈现在显示器的相应区域上的内容来动态地更新动作。 包含应答器读取器的用户设备检测来自一个应答器的信号以触发相应的动作。

    Signaling compression/decompression with improved efficiency
    9.
    发明申请
    Signaling compression/decompression with improved efficiency 有权
    信号压缩/减压,提高效率

    公开(公告)号:US20060262812A1

    公开(公告)日:2006-11-23

    申请号:US11188768

    申请日:2005-07-26

    摘要: The present invention relates to a method of compressing or decompressing a signaling message in a packet data network, wherein a parameter information is provided in a header portion of a protocol message of the packet data network. The parameter information specifies at least one processing detail of a compression or decompression mechanism and is forwarded together with the protocol message through the packet data network to a compression or decompression function of the packet data network. The compression or decompression mechanism at the compression or decompression function is then set in accordance with the parameter information. Thereby, a better compression of the first or first few messages can be achieved, as the parameter information is directly available.

    摘要翻译: 本发明涉及在分组数据网络中压缩或解压缩信令消息的方法,其中在分组数据网络的协议消息的报头部分中提供参数信息。 参数信息指定压缩或解压缩机制的至少一个处理细节,并且通过分组数据网络与协议消息一起转发到分组数据网络的压缩或解压缩功能。 然后根据参数信息设置压缩或解压缩功能处的压缩或解压缩机制。 因此,随着参数信息直接可用,可以实现对第一或第几几个消息的更好的压缩。

    Obtaining and notifying middle box information
    10.
    发明申请
    Obtaining and notifying middle box information 审中-公开
    获取并通知中间盒信息

    公开(公告)号:US20060013192A1

    公开(公告)日:2006-01-19

    申请号:US10966096

    申请日:2004-10-18

    申请人: Franck Le Zhigang Liu

    发明人: Franck Le Zhigang Liu

    IPC分类号: H04L12/28

    摘要: Signaling between a terminal equipment and a session server is provided which carries information on an expected media stream to or from the terminal equipment via a middle box for optimizing the performance of data communications between the terminal equipment and a correspondent node. On the basis of this information the session server is enabled to create appropriate entries in a security entity provided for the terminal equipment so that the media stream can successfully traverse the middle box and the security entity.

    摘要翻译: 提供终端设备和会话服务器之间的信令,其经由用于优化终端设备和通信节点之间的数据通信的性能的中间框,携带关于来自终端设备的预期媒体流的信息。 基于该信息,会话服务器能够在为终端设备提供的安全实体中创建适当的条目,使得媒体流可以成功地遍历中间盒和安全实体。