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公开(公告)号:US06436637B1
公开(公告)日:2002-08-20
申请号:US09206646
申请日:1998-12-07
申请人: Olga Bandman , Surya K. Goli , Preeti Lal , Neil C. Corley , Hong Zhang
发明人: Olga Bandman , Surya K. Goli , Preeti Lal , Neil C. Corley , Hong Zhang
IPC分类号: C12N916
摘要: The invention provides a human protein phosphatase (PROPHO) and polynucleotides which identify and encode PROPHO. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of PROPHO.
摘要翻译: 本发明提供了人蛋白磷酸酶(PROPHO)和识别和编码PROPHO的多核苷酸。 本发明还提供表达载体,宿主细胞,激动剂,抗体和拮抗剂。 本发明还提供了治疗与PROPHO表达相关的疾病的方法。
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公开(公告)号:US5853997A
公开(公告)日:1998-12-29
申请号:US873093
申请日:1997-06-11
申请人: Olga Bandman , Surya K. Goli , Preeti Lal , Neil C. Corley , Hong Zhang
发明人: Olga Bandman , Surya K. Goli , Preeti Lal , Neil C. Corley , Hong Zhang
IPC分类号: C12N15/09 , A61K38/00 , A61K38/46 , A61K45/00 , A61P29/00 , A61P35/00 , A61P43/00 , C07K16/40 , C12N9/16 , C12N15/55 , C12Q1/68 , C07H21/04 , C12N1/20
摘要: The invention provides a human protein phosphatase (PROPHO) and polynucleotides which identify and encode PROPHO. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of PROPHO.
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公开(公告)号:US5885803A
公开(公告)日:1999-03-23
申请号:US878989
申请日:1997-06-19
申请人: Olga Bandman , Jennifer L. Hillman , Neil C. Corley , Karl J. Guegler , Preeti Lal , Surya K. Goli , Purvi Shah
发明人: Olga Bandman , Jennifer L. Hillman , Neil C. Corley , Karl J. Guegler , Preeti Lal , Surya K. Goli , Purvi Shah
CPC分类号: C12N9/1205 , A61K38/00
摘要: The invention provides human disease associated protein kinases and polynucleotides (collectively designated DAPK) which identify and encode them. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention further provides methods for diagnosing and treating disorders associated with expression of human disease associated protein kinases.
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公开(公告)号:US06207148B1
公开(公告)日:2001-03-27
申请号:US09272796
申请日:1999-03-19
申请人: Olga Bandman , Jennifer L. Hillman , Neil C. Corley , Karl J. Guegler , Preeti Lal , Surya K. Goli , Purvi Shah
发明人: Olga Bandman , Jennifer L. Hillman , Neil C. Corley , Karl J. Guegler , Preeti Lal , Surya K. Goli , Purvi Shah
IPC分类号: A61K3843
CPC分类号: C12N9/1205 , A61K38/00
摘要: The invention provides human disease associated protein kinases and polynucleotides (collectively designated DAPK) which identify and encode them. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention further provides methods for diagnosing and treating disorders associated with expression of human disease associated protein kinases.
摘要翻译: 本发明提供了识别和编码它们的人类疾病相关蛋白激酶和多核苷酸(统称为DAPK)。 本发明还提供表达载体,宿主细胞,激动剂,抗体和拮抗剂。 本发明还提供用于诊断和治疗与人类疾病相关蛋白激酶的表达相关的疾病的方法。
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公开(公告)号:US06379913B1
公开(公告)日:2002-04-30
申请号:US09299689
申请日:1999-04-26
IPC分类号: C12N948
摘要: The present invention provides a human serine carboxypeptidase (CPEPT) and polynucleotides which identify and encode CPEPT. The invention also provides expression vectors, host cells, agonists, antibodies, and antagonists. The invention also provides methods for treating disorders associated with expression of CPEPT.
摘要翻译: 本发明提供了人丝氨酸羧肽酶(CPEPT)和识别和编码CPEPT的多核苷酸。 本发明还提供表达载体,宿主细胞,激动剂,抗体和拮抗剂。 本发明还提供了治疗与CPEPT表达相关的疾病的方法。
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公开(公告)号:US5925521A
公开(公告)日:1999-07-20
申请号:US828488
申请日:1997-03-31
IPC分类号: C12N15/09 , A61K38/00 , A61K39/395 , A61K45/00 , A61P3/10 , A61P9/10 , A61P9/12 , A61P13/12 , A61P25/00 , A61P25/14 , A61P25/16 , A61P25/28 , A61P39/02 , A61P43/00 , C07K16/40 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/48 , C12N9/64 , C12N15/57 , C12Q1/68 , C12N15/63
摘要: The present invention provides a human serine carboxypeptidase (CPEPT) and polynucleotides which identify and encode CPEPT. The invention also provides expression vectors, host cells, agonists, antibodies, and antagonists. The invention also provides methods for treating disorders associated with expression of CPEPT.
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公开(公告)号:US20110053217A1
公开(公告)日:2011-03-03
申请号:US12457389
申请日:2009-06-09
申请人: Preeti Lal , Y. Tom Tang , Gina A. Gorgone , Neil C. Corley , Karl J. Guegler , Mariah R. Baughn , Ingrid E. Akerblom , Janice Au-Young , Henry Yue , Chandra Patterson , Roopa Reddy , Jennifer L. Hillman , Olga Bandman
发明人: Preeti Lal , Y. Tom Tang , Gina A. Gorgone , Neil C. Corley , Karl J. Guegler , Mariah R. Baughn , Ingrid E. Akerblom , Janice Au-Young , Henry Yue , Chandra Patterson , Roopa Reddy , Jennifer L. Hillman , Olga Bandman
IPC分类号: C12P21/00 , C07H21/04 , C12N1/21 , C07H21/02 , C07K14/435
CPC分类号: G01N33/57419 , A61K38/00 , A61K38/1709 , A61K39/3955 , A61K45/06 , C07K14/47 , C07K16/18 , C07K16/40 , C07K2317/76 , G01N2333/916
摘要: The invention provides human signal peptide-containing proteins (HSPP) and polynucleotides which identify and encode HSPP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of HSPP.
摘要翻译: 本发明提供了人信号肽肽蛋白(HSPP)和识别和编码HSPP的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与HSPP表达相关的障碍的方法。
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公开(公告)号:US06242214B1
公开(公告)日:2001-06-05
申请号:US09063743
申请日:1998-04-21
申请人: Olga Bandman , Preeti Lal , Karl J. Guegler , Neil C. Corley , Chandra Patterson
发明人: Olga Bandman , Preeti Lal , Karl J. Guegler , Neil C. Corley , Chandra Patterson
IPC分类号: C12P2106
CPC分类号: C07K14/4706 , A61K38/00
摘要: The invention provides human GTPase-associated proteins (GPAP) and polynucleotides which identify and encode GPAP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of GPAP.
摘要翻译: 本发明提供了鉴定和编码GPAP的人GTP酶相关蛋白(GPAP)和多核苷酸。 本发明还提供了表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与GPAP表达相关的疾病的方法。
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公开(公告)号:US06171843B2
公开(公告)日:2001-01-09
申请号:US09088425
申请日:1998-06-01
IPC分类号: C12N990
CPC分类号: C12N9/90
摘要: The invention provides human peptidyl-prolyl isomerases (HPPIP) and polynucleotides which identify and encode HPPIP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of HPPIP.
摘要翻译: 本发明提供了鉴定和编码HPPIP的人肽基 - 脯氨酰异构酶(HPPIP)和多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与HPPIP表达相关的病症的方法。
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公开(公告)号:US6096308A
公开(公告)日:2000-08-01
申请号:US231529
申请日:1999-01-14
申请人: Preeti Lal , Jennifer L. Hillman , Olga Bandman , Neil C. Corley , Purvi Shah
发明人: Preeti Lal , Jennifer L. Hillman , Olga Bandman , Neil C. Corley , Purvi Shah
IPC分类号: C12N15/09 , A61K38/00 , A61K38/45 , A61K39/395 , A61P35/00 , A61P37/02 , A61P43/00 , C07K14/47 , C07K16/40 , C12N1/21 , C12N5/10 , C12N9/12 , C12N15/54 , C12P21/02 , C12Q1/68 , A61K38/51
CPC分类号: C12N9/1205 , C07K14/4703 , C12Q1/6883 , A61K38/00
摘要: The invention provides a human protein kinase (PK) and kinase inhibitors (PKI) and polynucleotides which identify and encode PK and PKI. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of PK and PKI.
摘要翻译: 本发明提供了鉴定和编码PK和PKI的人蛋白激酶(PK)和激酶抑制剂(PKI)和多核苷酸。 本发明还提供表达载体,宿主细胞,激动剂,抗体和拮抗剂。 本发明还提供用于诊断,治疗或预防与PK和PKI的表达相关的障碍的方法。
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