METHODS OF DETECTION USING ACOUSTO-MECHANICAL DETECTION SYSTEMS
    5.
    发明申请
    METHODS OF DETECTION USING ACOUSTO-MECHANICAL DETECTION SYSTEMS 审中-公开
    使用机械检测系统进行检测的方法

    公开(公告)号:US20100075347A1

    公开(公告)日:2010-03-25

    申请号:US12375731

    申请日:2007-08-15

    摘要: Methods for detecting target biological analytes within sample material using acousto-mechanical energy generated by a sensor are disclosed. The acousto-mechanical energy may be provided using an acousto-mechanical sensor, e.g., a surface acoustic wave sensor such as, e.g., a shear horizontal surface acoustic wave sensor (e.g., a LSH-SAW sensor). The detection of the target biological analytes in sample material are enhanced by coupling of the target biological analyte (e.g., through the use of magnetic particles), application of a magnetic field to draw the target analyte to the sensor surface, and subsequent removal of the magnetic field before measuring detection.

    摘要翻译: 公开了使用由传感器产生的声 - 机械能来检测样品材料内的目标生物分析物的方法。 声机械能可以使用诸如例如剪切水平声表面波传感器(例如LSH-SAW传感器)的表面声波传感器的声 - 机械传感器来提供。 通过将目标生物分析物(例如,通过使用磁性颗粒)的耦合,施加磁场以将目标分析物吸引到传感器表面,并随后将样品材料中的目标生物分析物除去 磁场测量前检测。

    MICROORGANISM-CAPTURING COMPOSITIONS AND METHODS
    6.
    发明申请
    MICROORGANISM-CAPTURING COMPOSITIONS AND METHODS 审中-公开
    微生物捕获组合物和方法

    公开(公告)号:US20110183398A1

    公开(公告)日:2011-07-28

    申请号:US12811142

    申请日:2008-12-23

    IPC分类号: C12N11/10 C12N1/20 C12M1/00

    摘要: The invention relates to compositions, methods, devices, and kits for non-specifically isolating bacterial cells. The compositions comprise a solid support which has a surface comprising a combination of a carbohydrate and a biotin-binding protein, wherein the protein is covalently bonded to the carbohydrate, and wherein the protein is linked to the solid support via the carbohydrate; and at least one of 1) a plurality of bacterial cells non-specifically bound to the combination of the carbohydrate and the protein or 2) an amphiphilic glycoside of a steroid or triterpene. The methods, devices, and kits include at least one of these compositions.

    摘要翻译: 本发明涉及用于非特异性分离细菌细胞的组合物,方法,装置和试剂盒。 所述组合物包含固体支持物,其具有包含碳水化合物和生物素结合蛋白的组合的表面,其中所述蛋白质与碳水化合物共价键合,并且其中所述蛋白质通过所述碳水化合物与所述固体支持物连接; 和1)与碳水化合物和蛋白质的组合非特异性结合的多个细菌细胞中的至少一个或2)类固醇或三萜烯的两亲糖苷。 方法,装置和试剂盒包括这些组合物中的至少一种。