公开(公告)号：US20080009534A1

公开(公告)日：2008-01-10

申请号：US11773564

申请日：2007-07-05

申请人： Peter Cheng ,  Sean Chen ,  Xinhua Qian ,  Rajendra Deshpande ,  Erqing Tang

发明人： Peter Cheng ,  Sean Chen ,  Xinhua Qian ,  Rajendra Deshpande ,  Erqing Tang

IPC分类号： A61K31/42 ,  A61P43/00 ,  C07D263/30

CPC分类号： C07D263/32

摘要： Compounds are provided which have the structure of Formula (I): wherein R is hydrogen or C1-C4 alkyl; and each of R1 and R2 is independently hydrogen, C1-C4 alkyl, halo or C1-C4 alkoxy, and salts thereof, which compounds are useful as antidiabetic, hypolipidemic, and antiobesity agents.

摘要翻译： 提供了具有式（I）结构的化合物：其中R是氢或C 1 -C 4烷基; 并且R 1和R 2各自独立地为氢，C 1 -C 4烷基，卤素或C 该化合物可用作抗糖尿病，降血脂药和抗肥胖剂。

公开(公告)号：US20070287713A1

公开(公告)日：2007-12-13

申请号：US11779319

申请日：2007-07-18

申请人： Peter Cheng ,  Sean Chen ,  Pratik Devasthale ,  Charles Ding ,  Timothy Herpin ,  Shung Wu ,  Hao Zhang ,  Wei Wang ,  Xiang-Yang Ye

发明人： Peter Cheng ,  Sean Chen ,  Pratik Devasthale ,  Charles Ding ,  Timothy Herpin ,  Shung Wu ,  Hao Zhang ,  Wei Wang ,  Xiang-Yang Ye

IPC分类号： A61K31/41 ,  A61K31/42 ,  A61K31/44 ,  A61K31/445 ,  A61K31/4965 ,  A61K31/497 ,  A61K31/505 ,  A61P3/10 ,  C07D239/02 ,  C07D257/00 ,  C07D263/30 ,  C07D271/06 ,  C07D401/02 ,  C07D403/02 ,  C07D413/02

CPC分类号： C07D413/12 ,  C07D413/14

摘要： wherein Z1 is (CH2)q or C═O; Z2 is (CH2)p or C═O; D is —CH═ or C═O or (CH2)m where m is 0, 1, 2 or 3; n=0, 1 or 2; p=1 or 2; q=0, 1 or 2; Q is C or N; A is (CH2)x where x is 1 to 5, or A is (CH2)x1, where x1 is 1 to 5 with an alkenyl bond or an alkynyl bond embedded anywhere in the chain, or A is —(CH2)x2—O—(CH2)x3— where x2 is 0 to 5 and x3 is 0 to 5, provided that at least one of x2 and x3 is other than 0; B is a bond or is (CH2)x4 where x4 is 1 to 5; X is CH or N; X2 is C, N, O or S; X3 is C, N, O or S; X4 is C, N, O or S; X5 is C, N, O or S; X6 is C, N, O or S; provided that at least one of X2, X3, X4 X5 and X6 is N; and at least one of X2, X3, X4 X5 and X6 is C. R1 is H or alkyl; R2 is H, alkyl, alkoxy, halogen, amino, substituted amino or cyano; R2a, R2b and R2c may be the same or different and are selected from H, alkyl, alkoxy, halogen, amino, substituted amino or cyano; and R3, E, Z and Y are as defined herein.

公开(公告)号：US20050119311A1

公开(公告)日：2005-06-02

申请号：US10964395

申请日：2004-10-13

申请人： Peter Cheng ,  Pratik Devasthale ,  Yoon Jeon ,  Sean Chen ,  Hao Zhang

发明人： Peter Cheng ,  Pratik Devasthale ,  Yoon Jeon ,  Sean Chen ,  Hao Zhang

IPC分类号： C07D263/32 ,  C07D263/58 ,  C07D277/24 ,  C07D413/12 ,  C07D413/14 ,  C07D417/04 ,  C07D417/12 ,  C07D495/04 ,  C07D521/00 ,  C07D417/14 ,  A61K31/4439 ,  A61K31/444

CPC分类号： C07D263/58 ,  C07D231/12 ,  C07D233/56 ,  C07D249/08 ,  C07D263/32 ,  C07D277/24 ,  C07D413/12 ,  C07D413/14 ,  C07D417/04 ,  C07D417/12 ,  C07D495/04

摘要： Compounds are provided which have the structure wherein Q is C or N, A is O or S, Z is O or a bond, X is CH or N and R1, R2, R2a, R2b, R2c, R3, Y, x, m, and n are as defined herein, which compounds are useful as antidiabetic, hypolipidemic, and antiobesity agents.

摘要翻译： 提供具有其中Q为C或N，A为O或S，Z为O或键，X为CH或N，R 1，R 2， R 2，R 2b，R 2b，R 2c，R 3，Y，x，m和 n如本文所定义，这些化合物可用作抗糖尿病，降血脂症和抗肥胖剂。

公开(公告)号：US20080021052A1

公开(公告)日：2008-01-24

申请号：US11769799

申请日：2007-06-28

申请人： Sean Chen ,  Peter Cheng ,  Rebecca Smirk

发明人： Sean Chen ,  Peter Cheng ,  Rebecca Smirk

IPC分类号： A61K31/426 ,  A61K31/4436 ,  A61K31/506 ,  A61P19/00 ,  A61P25/28 ,  A61P3/00 ,  A61P3/04 ,  A61P3/10 ,  A61P9/00 ,  C07D239/545 ,  C07D277/34 ,  C07D417/12

CPC分类号： C07D417/14 ,  C07D277/46 ,  C07D417/12

摘要： Compounds are provided which are glucokinase activators and thus are useful in treating diabetes and related diseases and have the structure wherein in the ring represents one or two double bonds; R1 is aryl or heteroaryl; R2 is halogen, cycloalkyl, heterocyclyl, aryl, or heteroaryl; R5 is as defined herein; Z is O, S, S(O), S(O)2, or NR5a; X is S, O, N, NR3, or CR3; Y is NCR4 or N4; R3, R4, and R5 are as defined herein; R8 is aryl or heteroaryl; R6 and R7 are independently H, halogen, or alkyl; m is 0 or 1; and n is 0 to 3, or a pharmaceutically acceptable salt thereof. A method for treating diabetes and related diseases employing the above compounds is also provided.

摘要翻译： 提供了作为葡糖激酶活化剂的化合物，因此可用于治疗糖尿病和相关疾病，并具有以下结构：其中表示一个或两个双键; R 1是芳基或杂芳基; R 2是卤素，环烷基，杂环基，芳基或杂芳基; R 5如本文所定义; Z是O，S，S（O），S（O）2或NR 5a; X是S，O，N，NR 3或CR 3; Y是NCR 4或NR 4; R 3，R 4和R 5如本文所定义; R 8是芳基或杂芳基; R 6和R 7独立地是H，卤素或烷基; m为0或1; 和n为0至3，或其药学上可接受的盐。 还提供了使用上述化合物治疗糖尿病和相关疾病的方法。

公开(公告)号：US20070015797A1

公开(公告)日：2007-01-18

申请号：US11155965

申请日：2005-08-22

申请人： Peter Cheng ,  Pratik Devasthale ,  Yoon Jeon ,  Sean Chen ,  Hao Zhang

发明人： Peter Cheng ,  Pratik Devasthale ,  Yoon Jeon ,  Sean Chen ,  Hao Zhang

IPC分类号： A61K31/4439 ,  A61K31/421 ,  C07D413/02 ,  C07D263/34

CPC分类号： C07D263/32 ,  C07D277/24 ,  C07D413/12 ,  C07D413/14 ,  C07D417/04 ,  C07D417/12 ,  C07D495/04

摘要： Compounds are provided which have the structure wherein Q is C or N, A is O or S, Z is O or a bond, X is CH or N and R1, R2, R2a, R2b, R2c, R3, Y, x, m, and n are as defined herein, which compounds are useful as antidiabetic, hypolipidemic, and antiobesity agents.

公开(公告)号：US20050119312A1

公开(公告)日：2005-06-02

申请号：US11016183

申请日：2004-12-17

申请人： Peter Cheng ,  Sean Chen ,  Charles Ding ,  Timothy Herpin

发明人： Peter Cheng ,  Sean Chen ,  Charles Ding ,  Timothy Herpin

IPC分类号： A61K31/41 ,  A61K31/42 ,  A61K31/435 ,  A61K31/50 ,  A61K31/52 ,  C07D233/54 ,  C07D249/06 ,  C07D263/32 ,  C07D271/06 ,  C07D413/12 ,  C07D417/14 ,  A61K31/4439 ,  A61K31/444 ,  C07D413/14

CPC分类号： C07D233/64 ,  C07D249/06 ,  C07D263/32 ,  C07D271/06 ,  C07D413/12

摘要： Compounds are provided which are useful as antidiabetic agents and antiobesity agents and have the structure wherein m is 0, 1 or 2; n is 0, 1 or 2; Q is C or N; A is (CH2)x where x is 1 to 5, or A is (CH2)x1 where x1 is 1 to 5 with an alkenyl bond or an alkynyl bond embedded anywhere in the chain, or A is —(CH2)x2—O—(CH2)x3— where x2 is 0 to 5 and x3 is 0 to 5, provided that at least one of x2 and x3 is other than 0; B is a bond or is (CH2)x4 where x4 is 1 to 5; X is CH or N; X2 is C, N, O or S; X3 is C, N, O or S; X4 is C, N; O or S; X5 is C, N, O or S; X6 is C, N, O or S; provided that at least one of X2, X3, X4 X5 and X6 is N; and at least one of X2, X3, X4 X5 and X6 is C, and specifically excluding the structure(s) as shown below: where X2═N, X3═C, X4═O or S, Z=O or a bond R1 is H or alkyl; R2 is H, alkyl, alkoxy, halogen, amino or substituted amino or cyano; R2a, R2b and R2c may be the same or different and are selected from H, alkyl, alkoxy, halogen, amino or substituted amino or cyano; and R3 and Y are as defined herein, which compounds are useful in treating diabetes and obesity.

公开(公告)号：US08222910B2

公开(公告)日：2012-07-17

申请号：US12504308

申请日：2009-07-16

申请人： Dilip Sangam ,  Hendrik Santo ,  Sean Chen ,  Minjong Kim ,  Sivaprakash Kannan ,  Balaji Virajpet

发明人： Dilip Sangam ,  Hendrik Santo ,  Sean Chen ,  Minjong Kim ,  Sivaprakash Kannan ,  Balaji Virajpet

IPC分类号： G01R31/02

CPC分类号： G01R31/3163 ,  G01R31/3187

摘要： The innovation relates to systems and/or methodologies for error detection during sub-assembly in high voltage analog circuits. A signal driver communicates test signals to one or more high voltage analog circuits, and a state machine compares the electrical and/or thermal responses of the high voltage analog circuits to a set of predetermined expected results (e.g., signatures). The signal driver and state machine can be incorporated into the high voltage analog circuits. The expected results can be stored in the target circuits in the form of look-up tables, matrices, and so forth. Errors, such as, dry solders and bridge solders can be determined based on the comparison of the obtained responses to the expected signatures.

摘要翻译： 该创新涉及用于在高压模拟电路中的子组装期间的错误检测的系统和/或方法。 信号驱动器将测试信号传送到一个或多个高压模拟电路，并且状态机将高压模拟电路的电和/或热响应与一组预定的预期结果（例如，签名）进行比较。 信号驱动器和状态机可以并入高压模拟电路。 预期结果可以以查询表，矩阵等的形式存储在目标电路中。 可以根据获得的对预期签名的响应的比较来确定干焊料和桥焊机等错误。

公开(公告)号：US08217887B2

公开(公告)日：2012-07-10

申请号：US12018399

申请日：2008-01-23

申请人： Dilip Sangam ,  Hendrik Santo ,  Tushar Dhayagude ,  Klen Vi ,  Sean Chen

发明人： Dilip Sangam ,  Hendrik Santo ,  Tushar Dhayagude ,  Klen Vi ,  Sean Chen

IPC分类号： G09G3/36

CPC分类号： G09G3/3426 ,  G09G3/3413 ,  G09G2310/0237 ,  G09G2310/024 ,  G09G2320/0633 ,  G09G2320/0666 ,  G09G2360/144

摘要： The present invention discloses apparatus and techniques relating to the intelligent control of a display's backlight LED strings. The present invention provides for controlling the display intensity on a region-by-region basis and for adjusting the intensity multiple times within the duration of a frame. The present invention also provides backlight adjustment in a manner that emphasizes certain colors and deemphasizes certain colors. The present invention also provides for adjustment of the backlight based on the ambient temperature.

摘要翻译： 本发明公开了与显示器的背光LED串的智能控制相关的装置和技术。 本发明提供了在逐帧的基础上控制显示强度并且在帧的持续时间内多次调整强度。 本发明还以强调某些颜色并且强调某些颜色的方式提供背光调整。 本发明还提供了基于环境温度来调节背光。

公开(公告)号：US20120072966A1

公开(公告)日：2012-03-22

申请号：US13305270

申请日：2011-11-28

申请人： Zesen Chen ,  Peter Chou ,  Sean Chen ,  Brian Gonsalves

发明人： Zesen Chen ,  Peter Chou ,  Sean Chen ,  Brian Gonsalves

IPC分类号： H04N21/40

CPC分类号： H04N21/231 ,  G06F17/30067 ,  H04N7/17318 ,  H04N21/23106 ,  H04N21/23113 ,  H04N21/26275 ,  H04N21/2747 ,  H04N21/4333 ,  H04N21/4335 ,  H04N21/47214 ,  H04N21/4728

摘要： Various embodiments of the disclosed subject matter provide methods and systems to record broadcast programming for at least one television channel for a period of time, wherein the recording is performed upstream from subscribers in a television distribution system, and further including after the period of time, keeping recorded programming by request from at least one subscriber. And further wherein the request is for at least one television program contained in the recorded programming or for a time window for a particular channel. According to another embodiment a subscriber requests that broadcast programming be saved for the subscriber upstream from the subscriber in a television distribution system, and wherein the subscriber may request the programming be saved for later viewing by the subscriber between the time the programming was broadcast and a later point in time.

摘要翻译： 所公开的主题的各种实施例提供用于在一段时间内为至少一个电视频道记录广播节目的方法和系统，其中在电视分配系统中的用户进行记录，并且还包括在一段时间之后， 通过来自至少一个订户的请求来保存记录的节目。 此外，其中该请求是针对包含在所记录的节目中的至少一个电视节目或针对特定频道的时间窗口。 根据另一个实施例，用户请求在电视分配系统中为订户上游节约用户的广播节目，并且其中用户可以在播放节目播放时间和节目播放时间之间请求编程节目以供用户稍后观看 稍后的时间点。

公开(公告)号：US20110186437A1

公开(公告)日：2011-08-04

申请号：US12732571

申请日：2010-03-26

申请人： James Huang ,  Sean Chen ,  Radium Huang

发明人： James Huang ,  Sean Chen ,  Radium Huang

IPC分类号： C25D5/18

CPC分类号： C25D5/18

摘要： Disclosed is a polymeric electret film as well as the method of manufacturing the same. The polymeric electret film comprises a polytetrafluoroethylene film and an electrode layer. The polytetrafluoroethylene film includes a porous layer, which has a porous structure. The porous structure has a pore diameter ranging between 0.01 μm and 5.0 μm and has a porosity ranging between 20% and 95%. The polytetrafluoroethylene film has a thickness ranging between 1 μm and 50 μm, and is preferably made of expanded porous polytetrafluoroethylene. The polymeric electret film has a surface potential ranging between 0.1 V and 1000 V.

摘要翻译： 公开了一种聚合物驻极体膜及其制造方法。 聚合物驻极体膜包括聚四氟乙烯膜和电极层。 聚四氟乙烯膜包括具有多孔结构的多孔层。 多孔结构的孔径在0.01μm和5.0μm之间，孔隙率在20％和95％之间。 聚四氟乙烯膜的厚度为1μm以上且50μm以下，优选为膨胀多孔质聚四氟乙烯。 聚合物驻极体膜的表面电位范围为0.1V至1000V。