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88 条记录 (耗时 0.043 秒)

    Digital imaging system for assays in well plates, gels and blots
    1.
    发明授权
    Digital imaging system for assays in well plates, gels and blots 失效
    用于孔板，凝胶和印迹中的测定的数字成像系统

    公开(公告)号：US06441973B1

    公开(公告)日：2002-08-27

    申请号：US09240649

    申请日：1999-01-29

    申请人： Peter Ramm ,  Gang Sun ,  Rolf Mueller ,  Timothy Ormsby ,  Kenneth R. Castle

    发明人： Peter Ramm ,  Gang Sun ,  Rolf Mueller ,  Timothy Ormsby ,  Kenneth R. Castle

    IPC分类号： G02B934

    CPC分类号： G01N21/6452 ,  G01N21/6456 ,  G01N21/76 ,  G02B13/14 ,  G02B13/22 ,  G02B21/084 ,  G06T7/75 ,  G06T2207/10056 ,  G06T2207/30072

    摘要： An electronic imaging system is disclosed, for assessing the intensity of colorimetric, fluorescent or luminescent signal in a matrix consisting of wells, microwells, hybridization dot blots on membranes, gels, or other specimens. The system includes a very sensitive area CCD detector, a fast, telecentric lens with epi-illumination, a reflective/transmissive illumination system, an illumination wavelength selection device, and a light-tight chamber. A computer and image analysis software are used to control the hardware, correct and calibrate the images, and detect and quantify targets within the images.

    摘要翻译： 公开了一种电子成像系统，用于评估由孔，微孔，膜，凝胶或其它样品上的杂交点印迹组成的基质中的比色，荧光或发光信号的强度。 该系统包括非常敏感的区域CCD检测器，具有外部照明的快速远心透镜，反射/透射照明系统，照明波长选择装置和不透光室。 计算机和图像分析软件用于控制硬件，校正和校准图像，并检测和量化图像中的目标。

    Digital imaging system for assays in well plates, gels and blots
    2.
    发明授权
    Digital imaging system for assays in well plates, gels and blots 失效
    用于孔板，凝胶和印迹中的测定的数字成像系统

    公开(公告)号：US06381058B2

    公开(公告)日：2002-04-30

    申请号：US09854035

    申请日：2001-05-10

    申请人： Peter Ramm ,  Gang Sun ,  Rolf Mueller ,  Timothy Ormsby ,  Kenneth R. Castle

    发明人： Peter Ramm ,  Gang Sun ,  Rolf Mueller ,  Timothy Ormsby ,  Kenneth R. Castle

    IPC分类号： G02F103

    CPC分类号： G01N21/6452 ,  G01N21/6456 ,  G01N21/76 ,  G02B13/14 ,  G02B13/22 ,  G02B21/084 ,  G06T7/75 ,  G06T2207/10056 ,  G06T2207/30072

    摘要： An electronic imaging system is disclosed, for assessing the intensity of calorimetric, fluorescent or luminescent signal in a matrix consisting of wells, microwells, hybridization dot blots on membranes, gels, or other specimens. The system includes a very sensitive area CCD detector, a fast, telecentric lens with epi-illumination, a reflective/transmissive illumination system, an illumination wavelength selection device, and a light-tight chamber. A computer and image analysis software are used to control the hardware, correct and calibrate the images, and detect and quantify targets within the images.

    摘要翻译： 公开了一种电子成像系统，用于评估由孔，微孔，膜，凝胶或其它样品上的杂交点印迹组成的基质中的量热，荧光或发光信号的强度。 该系统包括非常敏感的区域CCD检测器，具有外部照明的快速远心透镜，反射/透射照明系统，照明波长选择装置和不透光室。 计算机和图像分析软件用于控制硬件，校正和校准图像，并检测和量化图像中的目标。

    Digital imaging system for assays in well plates, gels and blots
    5.
    发明授权
    Digital imaging system for assays in well plates, gels and blots 有权
    用于孔板，凝胶和印迹中的测定的数字成像系统

    公开(公告)号：US06345115B1

    公开(公告)日：2002-02-05

    申请号：US09477444

    申请日：2000-01-04

    申请人： Peter Ramm ,  Gang Sun

    发明人： Peter Ramm ,  Gang Sun

    IPC分类号： G06K900

    CPC分类号： G06T7/73 ,  G06T2207/30072

    摘要： A method and apparatus are disclosed for use in an area digital imaging system for assays to extract targets on a specimen containing an array of targets that may not be arranged in perfect regularity. A matrix is defined of nominal target locations including a probe template of predefined, two-dimensional size and shape at each of a plurality of fixed, predefined grid points on the specimen, and a determination is made of the most probable location of the probe template corresponding to a specific target by sensing both pixel intensity and the spatial distribution of pixel intensities in an image of the specimen at a plurality of locations in the vicinity of a nominal target location.

    摘要翻译： 公开了一种用于区域数字成像系统中的方法和装置，用于在包含可能未以完美规则排列的目标阵列的样本上提取目标的测定。 矩阵定义为标称目标位置，包括在样本上的多个固定的预定网格点中的每一个上的预定义的二维尺寸和形状的探针模板，并且确定探针模板的最可能的位置 通过在标称目标位置附近的多个位置处感测样本的图像中的像素强度和像素强度的空间分布来对应于特定目标。

    Method for thermal cycling of microfluidic samples
    7.
    发明授权
    Method for thermal cycling of microfluidic samples 有权
    微流体样品的热循环方法

    公开(公告)号：US09168531B2

    公开(公告)日：2015-10-27

    申请号：US13429861

    申请日：2012-03-26

    申请人： Jake Kimball ,  Brandon Ripley ,  Gang Sun ,  Dominique Toppani ,  Myo Thu Maung

    发明人： Jake Kimball ,  Brandon Ripley ,  Gang Sun ,  Dominique Toppani ,  Myo Thu Maung

    IPC分类号： C12P19/34 ,  B01L7/00 ,  C12Q3/00 ,  B01L3/00 ,  G01N21/64 ,  G01N21/76

    CPC分类号： B01L7/52 ,  B01L3/5027 ,  B01L2200/025 ,  B01L2200/147 ,  B01L2300/0819 ,  B01L2300/0893 ,  B01L2300/1805 ,  B01L2300/1822 ,  C12P19/34 ,  C12Q3/00 ,  G01N21/6408 ,  G01N21/6428 ,  G01N21/6456 ,  G01N21/76

    摘要： A thermal cycler for a microfluidic device includes a controller operable to provide a series of electrical signals, a heat sink, and a heating element in thermal communication with the heat sink and operable to receive the series of electrical signals from the controller. The thermal cycler also includes a thermal chuck in thermal communication with the heating element. The thermal chuck comprises a heating surface operable to make thermal contact with the microfluidic device. The heating surface is characterized by a temperature ramp rate between 2.5 degrees Celsius per second and 5.5 degrees Celsius per second and a temperature difference between a first portion of the heating surface supporting a first portion of the microfluidic device and a second portion of the heating surface supporting a second portion of the microfluidic device is less than 0.25° C.

    摘要翻译： 用于微流体装置的热循环仪包括控制器，其可操作以提供与散热器热连通的一系列电信号，散热器和加热元件，并可操作以从控制器接收一系列电信号。 热循环仪还包括与加热元件热连通的热卡盘。 热卡盘包括可操作以与微流体装置进行热接触的加热表面。 加热表面的特征在于每秒2.5摄氏度和5.5摄氏度/秒之间的温度升高速率，并且支撑微流体装置的第一部分的加热表面的第一部分与加热表面的第二部分之间的温度差 支撑微流体装置的第二部分小于0.25℃

    Electrically controlled medium for modulating light
    8.
    发明授权
    Electrically controlled medium for modulating light 有权
    用于调制光的电磁介质

    公开(公告)号：US08357312B2

    公开(公告)日：2013-01-22

    申请号：US12988620

    申请日：2008-05-16

    申请人： Gang Sun

    发明人： Gang Sun

    IPC分类号： C09K19/00 ,  C09K19/06 ,  C09K19/32 ,  C09K19/52 ,  G03C1/1333

    CPC分类号： C09K19/542 ,  C09K19/52 ,  C09K19/58 ,  G02F1/1334 ,  G02F1/134336 ,  G02F1/13781 ,  G02F2203/30 ,  Y10T428/10 ,  Y10T428/1036

    摘要： An electrically controlled medium for modulating light includes two plastic thin film layers (1) and (2), and a mixture layer (3) is arranged between the two plastic thin film layers (1) and (2). The mixture layer (3) is consisted of smectic liquid crystals (31), polymer materials (33) and dopants (32). Electrode layers (4) are coated on one side of each of the two plastic thin film layers (1) and (2) facing to the mixture layer (3), and the electrode layers (4) are connected to a device of electrical driving system (5). The liquid crystal molecules are allowed to exhibit different molecule alignments by controlling the amplitude, frequency and driving time of the electric power applied to the electrode layers (4), so that the electrically controlled medium for modulating light can be switched between a blurredly scattering state and a fully transparent state, even may be switched among a plurality of gradual translucent states of different gray levels. The medium is power saving, hard to be broken and eco friendly and it can maintain its state after power is off (memory effect). It has fast switching speed and can be broadly used for the fields of architectural decoration, privacy control areas, automotive electronics and glass, etc.

    摘要翻译： 用于调制光的电控介质包括两个塑料薄膜层（1）和（2），并且在两个塑料薄膜层（1）和（2）之间布置有混合层（3）。 混合层（3）由近晶液晶（31），聚合物材料（33）和掺杂剂（32）组成。 电极层（4）涂覆在两个塑料薄膜层（1）和（2）的面对混合层（3）的一侧上，并且电极层（4）连接到电驱动装置 系统（5）。 通过控制施加到电极层（4）的电力的振幅，频率和驱动时间，允许液晶分子显示不同的分子对准，使得用于调制光的电控介质可以在模糊散射状态 并且完全透明状态，甚至可以在不同灰度级的多个渐变半透明状态之间切换。 介质节电，难破，环保，电源关闭后可保持状态（记忆效应）。 开关速度快，可广泛应用于建筑装饰，隐私控制领域，汽车电子和玻璃等领域。

    POLARIZATION IMAGING
    9.
    发明申请
    POLARIZATION IMAGING 有权
    极化成像

    公开(公告)号：US20120070065A1

    公开(公告)日：2012-03-22

    申请号：US13202251

    申请日：2010-02-17

    申请人： Scott A. Balak ,  Gang Sun

    发明人： Scott A. Balak ,  Gang Sun

    IPC分类号： G06K9/00 ,  G01J4/00

    CPC分类号： G01N21/88 ,  G01N21/21

    摘要： Methods of monitoring critical dimensions in a semiconductor fabrication process include capturing at least one image of a first structure that has an effect on the polarization state of light reflected therefrom. For at least some of the first structure images, a value is calculated indicative of intensity of light reflected from the first structure. A critical dimension of the first structure is obtained and correlated with the calculated value. At least one image of a subsequent structure is captured. A determination is made, based at least in part on the calculated value, of a critical dimension of the subsequent structure.

    摘要翻译： 在半导体制造工艺中监测关键尺寸的方法包括捕获对从其反射的光的偏振状态具有影响的第一结构的至少一个图像。 对于至少一些第一结构图像，计算指示从第一结构反射的光的强度的值。 获得第一结构的临界尺寸并与计算值相关。 捕获后续结构的至少一个图像。 至少部分地基于计算值确定后续结构的关键维度。