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公开(公告)号：US09828597B2
公开(公告)日：2017-11-28
申请号：US11562503
申请日：2006-11-22
申请人： Ping Wang , Minjuan Zhang , Hongfei Jia , Archana H. Trivedi , Masahiko Ishii
发明人： Ping Wang , Minjuan Zhang , Hongfei Jia , Archana H. Trivedi , Masahiko Ishii
CPC分类号： C12N11/14 , C09D5/14 , C09D5/1637 , C09D5/1687 , C12N9/20 , C12N9/54 , C12N9/96 , C12N11/04 , C12N11/06 , C12Y304/21062
摘要： The present invention relates to compositions and a process in the field of self-cleaning system using digestive proteins. One composition includes a substrate, a digestive protein capable of decomposing a stain molecule, and a link moiety bound to both said digestive protein and said substrate. An alternative composition includes a digestive protein capable of decomposing a stain molecule and a coating substrate wherein said digestive protein may be dispersed in said coating substrate. The process claim includes binding a substrate to a surface and forming a linker moiety between a digestive protein and said substrate.
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公开(公告)号：US20080119381A1
公开(公告)日：2008-05-22
申请号：US11562503
申请日：2006-11-22
申请人： Ping Wang , Minjuan Zhang , Hongfei Jia , Archana H. Trivedi , Masahiko Ishii
发明人： Ping Wang , Minjuan Zhang , Hongfei Jia , Archana H. Trivedi , Masahiko Ishii
CPC分类号： C12N11/14 , C09D5/14 , C09D5/1637 , C09D5/1687 , C12N9/20 , C12N9/54 , C12N9/96 , C12N11/04 , C12N11/06 , C12Y304/21062
摘要： The present invention relates to compositions and a process in the field of self-cleaning system using digestive proteins. One composition includes a substrate, a digestive protein capable of decomposing a stain molecule, and a link moiety bound to both said digestive protein and said substrate. An alternative composition includes a digestive protein capable of decomposing a stain molecule and a coating substrate wherein said digestive protein may be dispersed in said coating substrate. The process claim includes binding a substrate to a surface and forming a linker moiety between a digestive protein and said substrate.
摘要翻译： 本发明涉及组合物和使用消化蛋白的自清洁系统领域的方法。 一种组合物包括底物，能够分解染色分子的消化蛋白，以及与所述消化蛋白和所述底物结合的连接部分。 替代组合物包括能够分解染色分子的消化蛋白和包衣基质，其中所述消化蛋白可以分散在所述包衣基质中。 方法权利要求包括将底物结合到表面并在消化蛋白和所述底物之间形成接头部分。
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3.发明申请Coatings Containing Polymer Modified Enzyme For Stable Self-Cleaning Of Organic Stains 有权含有聚合物改性酶的涂料用于有机污渍的稳定自清洁公开(公告)号：US20130065291A1
公开(公告)日：2013-03-14
申请号：US13229277
申请日：2011-09-09
申请人： Hongfei Jia , Ping Wang , Liting Zhang , Andreas Buthe , Xueyan Zhao , Songtao Wu , Masahiko Ishii , Minjuan Zhang
发明人： Hongfei Jia , Ping Wang , Liting Zhang , Andreas Buthe , Xueyan Zhao , Songtao Wu , Masahiko Ishii , Minjuan Zhang
IPC分类号： C09D189/00
CPC分类号： C09D189/00 , A61K47/60 , C08G65/33337 , C08L2203/02 , C08L2205/02 , C09D5/024 , C09D7/40 , C09D175/16 , C12N9/14 , C12N9/20 , C12N9/2408 , C12N9/2411 , C12N9/54 , C12N9/96 , C12N11/06 , C12N11/08
摘要： Bioactive coatings that are stabilized against inactivation by weathering are provided including a base associated with a chemically modified enzyme, and, optionally a first polyoxyethylene present in the base and independent of the enzyme. The coatings are optionally overlayered onto a substrate to form an active coating facilitating the removal of organic stains or organic material from food, insects, or the environment.
摘要翻译： 提供了通过耐风化来防止灭活的生物活性涂层，包括与化学修饰的酶相关的碱，以及任选地存在于碱中并独立于酶的第一聚氧乙烯。 涂层任选地覆盖在基底上以形成有助于从食品，昆虫或环境中去除有机污渍或有机材料的活性涂层。
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公开(公告)号：US08252571B2
公开(公告)日：2012-08-28
申请号：US12434320
申请日：2009-05-01
申请人： Ping Wang , Songtao Wu , Hongfei Jia , Masahiko Ishii , Xiaodong Tong , Minjuan Zhang
发明人： Ping Wang , Songtao Wu , Hongfei Jia , Masahiko Ishii , Xiaodong Tong , Minjuan Zhang
IPC分类号： C12N9/00 , C08F283/00
CPC分类号： C12N11/08 , C07K17/08 , C08L89/00 , C09D5/025 , C09D5/1637 , C08L2666/02
摘要： Processes for preparation of a protein-polymer composite material are provided according to embodiments of the present invention which include providing an admixture of a polymer resin, a surfactant and a non-aqueous organic solvent. An aqueous solution containing bioactive proteins and substantially free of surfactant is mixed with the admixture. The emulsion is mixed with a crosslinker to produce a curable composition. The curable composition is cured, thereby producing the protein-polymer composite material.
摘要翻译： 根据本发明的实施方案提供了制备蛋白质 - 聚合物复合材料的方法，其包括提供聚合物树脂，表面活性剂和非水有机溶剂的混合物。 含有生物活性蛋白质且基本上不含表面活性剂的水溶液与混合物混合。 将乳液与交联剂混合以制备可固化组合物。 固化组合物固化，由此制备蛋白质 - 聚合物复合材料。
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公开(公告)号：US20100279376A1
公开(公告)日：2010-11-04
申请号：US12434320
申请日：2009-05-01
申请人： Ping Wang , Songtao Wu , Hongfei Jia , Masahiko Ishii , Xiaodong Tong , Minjuan Zhang
发明人： Ping Wang , Songtao Wu , Hongfei Jia , Masahiko Ishii , Xiaodong Tong , Minjuan Zhang
CPC分类号： C12N11/08 , C07K17/08 , C08L89/00 , C09D5/025 , C09D5/1637 , C08L2666/02
摘要： Processes for preparation of a protein-polymer composite material are provided according to embodiments of the present invention which include providing an admixture of a polymer resin, a surfactant and a non-aqueous organic solvent. An aqueous solution containing bioactive proteins and substantially free of surfactant is mixed with the admixture. The emulsion is mixed with a crosslinker to produce a curable composition. The curable composition is cured, thereby producing the protein-polymer composite material.
摘要翻译： 根据本发明的实施方案提供了制备蛋白质 - 聚合物复合材料的方法，其包括提供聚合物树脂，表面活性剂和非水有机溶剂的混合物。 含有生物活性蛋白质且基本上不含表面活性剂的水溶液与混合物混合。 将乳液与交联剂混合以制备可固化组合物。 固化组合物固化，由此制备蛋白质 - 聚合物复合材料。
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公开(公告)号：US20080293117A1
公开(公告)日：2008-11-27
申请号：US12118171
申请日：2008-05-09
申请人： Ping Wang , Songtao Wu , Hongfei Jia , Masahiko Ishii , Xiaodong Tong , Minjuan Zhang
发明人： Ping Wang , Songtao Wu , Hongfei Jia , Masahiko Ishii , Xiaodong Tong , Minjuan Zhang
IPC分类号： C12N11/00
CPC分类号： A61K9/06 , A61K38/443 , A61K38/4826 , A61K45/06 , A61K47/32 , A61K2300/00
摘要： A bioactive composition includes a hydrogel matrix. At least one protein is immobilized in the hydrogel matrix. The digestive protein has a half-life at least 1000 times longer than the half-life of a free digestive protein counterpart.
摘要翻译： 生物活性组合物包括水凝胶基质。 至少一种蛋白质固定在水凝胶基质中。 消化蛋白的半衰期比游离消化蛋白对应物的半衰期长至少1000倍。
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公开(公告)号：US08222015B2
公开(公告)日：2012-07-17
申请号：US12118171
申请日：2008-05-09
申请人： Ping Wang , Songtao Wu , Hongfei Jia , Masahiko Ishii , Xiaodong Tong , Minjuan Zhang
发明人： Ping Wang , Songtao Wu , Hongfei Jia , Masahiko Ishii , Xiaodong Tong , Minjuan Zhang
CPC分类号： A61K9/06 , A61K38/443 , A61K38/4826 , A61K45/06 , A61K47/32 , A61K2300/00
摘要： A bioactive composition includes a hydrogel matrix. At least one protein is immobilized in the hydrogel matrix. The digestive protein has a half-life at least 1000 times longer than the half-life of a free digestive protein counterpart.
摘要翻译： 生物活性组合物包括水凝胶基质。 至少一种蛋白质固定在水凝胶基质中。 消化蛋白的半衰期比游离消化蛋白对应物的半衰期长至少1000倍。
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8.发明申请BIOACTIVE COMPOSITION INCLUDING STABILIZED PROTEIN AND PROCESS FOR PRODUCING THE SAME 审中-公开包括稳定蛋白质的生物组合物及其生产方法公开(公告)号：US20120093802A1
公开(公告)日：2012-04-19
申请号：US12903312
申请日：2010-10-13
申请人： Ping Wang , Songtao Wu , Hongfei Jia , Masahiko Ishii , Minjuan Zhang
发明人： Ping Wang , Songtao Wu , Hongfei Jia , Masahiko Ishii , Minjuan Zhang
IPC分类号： A61K38/48 , A61K38/47 , A61K38/46 , A61K38/44 , A61P37/08 , A61K39/395 , A61K31/7105 , A61K38/22 , A61K31/727 , A61K31/715 , A61K38/51
CPC分类号： C12N11/04 , A61K31/7105 , A61K31/715 , A61K31/727
摘要： A bioactive composition includes a porous hydrogel matrix. At least one protein is immobilized in the porous hydrogel matrix forming a hydrogel protein composite that is stable in an organic solvent. A process for stabilizing a bioactive composition includes the steps of: forming hydrogel matrix pores around protein molecules and reducing a water content within the hydrogel matrix pores forming a hydrogel protein composite that is stable in an organic solvent.
摘要翻译： 生物活性组合物包括多孔水凝胶基质。 将至少一种蛋白质固定在多孔水凝胶基质中，形成在有机溶剂中稳定的水凝胶蛋白复合物。 用于稳定生物活性组合物的方法包括以下步骤：在蛋白质分子周围形成水凝胶基质孔，并降低水凝胶基质孔内的含水量，形成在有机溶剂中稳定的水凝胶蛋白复合物。
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9.发明授权Coatings containing polymer modified enzyme for stable self-cleaning of organic stains 有权含有聚合物改性酶的涂料用于有机污渍的稳定自清洁公开(公告)号：US09121016B2
公开(公告)日：2015-09-01
申请号：US13229277
申请日：2011-09-09
申请人： Hongfei Jia , Ping Wang , Liting Zhang , Andreas Buthe , Xueyan Zhao , Songtao Wu , Masahiko Ishii , Minjuan Zhang
发明人： Hongfei Jia , Ping Wang , Liting Zhang , Andreas Buthe , Xueyan Zhao , Songtao Wu , Masahiko Ishii , Minjuan Zhang
IPC分类号： C12N11/08 , C09D5/16 , C12N11/06 , C09D5/02 , C09D7/12 , C12N9/14 , C12N9/20 , C12N9/26 , C12N9/54 , C12N9/96 , A61K47/48 , C08G65/333
CPC分类号： C09D189/00 , A61K47/60 , C08G65/33337 , C08L2203/02 , C08L2205/02 , C09D5/024 , C09D7/40 , C09D175/16 , C12N9/14 , C12N9/20 , C12N9/2408 , C12N9/2411 , C12N9/54 , C12N9/96 , C12N11/06 , C12N11/08
摘要： Bioactive coatings that are stabilized against inactivation by weathering are provided including a base associated with a chemically modified enzyme, and, optionally a first polyoxyethylene present in the base and independent of the enzyme. The coatings are optionally overlayered onto a substrate to form an active coating facilitating the removal of organic stains or organic material from food, insects, or the environment.
摘要翻译： 提供了通过耐风化来防止灭活的生物活性涂层，包括与化学修饰的酶相关的碱，以及任选地存在于碱中并独立于酶的第一聚氧乙烯。 涂层任选地覆盖在基底上以形成有助于从食品，昆虫或环境中去除有机污渍或有机材料的活性涂层。
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公开(公告)号：US20120252090A1
公开(公告)日：2012-10-04
申请号：US13525714
申请日：2012-06-18
申请人： Ping Wang , Songtao Wu , Hongfei Jia , Masahiko Ishii , Xiaodong Tong , Minjuan Zhang
发明人： Ping Wang , Songtao Wu , Hongfei Jia , Masahiko Ishii , Xiaodong Tong , Minjuan Zhang
IPC分类号： C12N11/08
CPC分类号： A61K9/06 , A61K38/443 , A61K38/4826 , A61K45/06 , A61K47/32 , A61K2300/00
摘要： A process for stabilizing a bioactive composition includes forming hydrogel matrix pores around protein molecules and reducing a water content within the hydrogel matrix pores while keeping the protein molecules biologically active.
摘要翻译： 用于稳定生物活性组合物的方法包括在蛋白质分子周围形成水凝胶基质孔，并且在保持蛋白质分子生物活性的同时降低水凝胶基质孔内的水含量。
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