摘要:
Biaryl substituted thiazole, oxazole and imidazole compounds are sodium channel blockers useful for the treatment of pain. Pharmaceutical compositions comprise an effective amount of the instant compounds, either alone, or in combination with one or more therapeutically active compounds, and a pharmaceutically acceptable carrier. Methods of treatment or prevention of conditions, including acute pain, chronic pain, visceral pain, inflammatory pain, and neuropathic pain comprise administering an effective amount of the present compounds, either alone, or in combination with one or more therapeutically active compounds.
摘要:
Biaryl substituted pyrazole compounds are sodium channel blockers useful for the treatment of pain and other conditions. Pharmaceutical compositions comprise an effective amount of the instant compounds, either alone, or in combination with one or more therapeutically active compounds, and a pharmaceutically acceptable carrier. Methods of treatment of conditions, including acute pain, chronic pain, visceral pain, inflammatory pain, and neuropathic pain, comprise administering an effective amount of the present compounds, either alone, or in combination with one or more therapeutically active compounds.
摘要:
Biaryl substituted triazole compounds represented by Formula I, II or III, or pharmaceutically acceptable salts thereof, and a process for making such compounds and salts thereof. Pharmaceutical compositions comprise an effective amount of the instant compounds, either alone, or in combination with one or more other therapeutically active compounds, and a pharmaceutically acceptable carrier. Methods of treating conditions associated with, or caused by, sodium channel activity, including, for example, acute pain, chronic pain, visceral pain, inflammatory pain, neuropathic pain, epilepsy, irritable bowel syndrome, depression, anxiety, multiple sclerosis, and bipolar disorder, comprise administering an effective amount of the present compounds, either alone, or in combination with one or more other therapeutically active compounds. A method of administering local anesthesia comprises administering an effective amount of a compound of the instant invention, either alone, or in combination with one or more other therapeutically active compounds, and a pharmaceutically acceptable carrier.
摘要:
An orally administered composition for relieving or eliminating snoring is described. The composition generally has four mechanisms of action for combating snoring. The composition includes a tissue-firming or astringent agent to firm up throat tissue. The composition also includes a soothing agent to soothe irritated or inflamed tissues. Also included in the composition is a lubricant to moisten dry or dehydrated tissues, and a mucous-thinning or expectorant agent to help remove any obstructive matter near the throat tissues.
摘要:
A remote monitoring and alerting system includes one or more remote terminal units and a central system, with both the central system and each remote terminal unit adapted to send and receive data across a communications network. Each remote terminal unit includes a processor and wireless transmitter in a compact arrangement that allows the unit to be placed conveniently in a housing associated with some remote device to be monitored. The central system includes a data collection and manipulation controller for receiving, processing, and storing data received from each remote terminal unit across the communications network. Both a user messaging controller and a user interface controller are also included in the central system. The user messaging controller transmits user messages through a suitable interface to one or more user designated devices in response to a remote terminal unit message received from the remote terminal unit. The user interface controller provides a user interface between a user of the remote monitoring and alerting system and the central system.
摘要:
An IP network includes a central entity and at least one customer premises equipment (CPE) device. The central entity generates a program clock reference (PCR) clock and provides audio-visual packets to a CPE based on the PCR clock. The CPE sets a first clock based on the PCR clock for decoding operations. The CPE sets a second clock that is independent from the first clock for audio and video output operations. For example, the CPE can process the audio-visual packets using the second clock.
摘要:
A mechanism for sharing files, and sets of related files, or packages of files, in a multi-host, multi-platform environment is provided. A public package client handles user requests to perform operations on a software package. Additionally, information about the package and the files contained therein may be obtained. A server, responsive to the client, performs the operations on the package. Data about the files is set in a data structure which may be stored in an archive along with the files themselves. In particular, this data may identify each file as either a text or binary file and as an executable file. A client may access the aforementioned data to determine if the file or files require further processing to adapt the file to the operating system on the client. Such processing may, for example, include linefeed/carriage return translation and codepage translation, or setting file attributes.
摘要:
An IP network includes a central entity and at least one customer premises equipment (CPE) device. The central entity generates a program clock reference (PCR) clock and provides audio-visual packets to a CPE based on the PCR clock. The CPE sets a first clock based on the PCR clock for decoding operations. The CPE sets a second clock that is independent from the first clock for audio and video output operations. For example, the CPE can process the audio-visual packets using the second clock.
摘要:
A video stream demultiplxer receives video streams comprising a selected current content channel and one or more adjacent content channels. Time stamp management is concurrently performed on the adjacent content channels while decoding the selected current content channel. Timing information such as Decoding Time Stamp (DTS) and Presentation Time Stamp (PTS) values, and/or random access points (RAPs) may be determined for pictures stored for the selected current content channel and the adjacent content channels. The determined timing information is utilized to determine a Program Clock Reference (PCR) value for each of the selected current channel and the adjacent channels for channel monitoring. A timebase, derived from a PCR rate that is determined based on the determined PCR value, is determined for decoding the selected current content channel. An adjacent content channel, which is primed during decoding of the selected current content channel, may be directly decoded for display if selected.
摘要:
Methods of optimizing a plurality of numerically controlled delay lines (NCDLS) in a DDR memory controller are presented herein. In one embodiment, a method may comprise, for example, one or more of the following: acquiring a plurality of statistics, the plurality of statistics defining an operating region for the DDR memory controller; and calculating optimal values for the plurality of NCDLs, the optimal values calculated using the plurality of statistics.