公开(公告)号：US20220257953A1

公开(公告)日：2022-08-18

申请号：US17728872

申请日：2022-04-25

申请人： Pulson, Inc.

发明人： Jeffery L. Bleich ,  Paul Mannheimer ,  Darin Howard Buxbaum

IPC分类号： A61N1/365

摘要： The present invention is generally directed to methods, systems, and computer program products for coordinating musculoskeletal and cardiovascular hemodynamics. In some embodiments, a heart pacing signal causes heart contractions to occur with an essentially constant time relationship with respect to rhythmic musculoskeletal activity. In other embodiments, prompts (e.g., audio, graphical, etc.) are provided to a user to assist them in timing of their rhythmic musculoskeletal activity relative to timing of their cardiovascular cycle. In further embodiments, accurately indicating a heart condition during a cardiac stress test is increased.

公开(公告)号：US09956470B2

公开(公告)日：2018-05-01

申请号：US15650130

申请日：2017-07-14

申请人： Pulson, Inc.

发明人： Jeffery L. Bleich ,  Paul Mannheimer

IPC分类号： A63B71/06 ,  A61B5/11 ,  A61B5/0205 ,  G06F19/00 ,  G09B19/00 ,  A63B22/02 ,  A63B15/00 ,  A63B69/00 ,  G09B23/28 ,  A61B5/0456 ,  A63B21/002 ,  A63B24/00 ,  A63B23/12 ,  A63B22/06 ,  A63B22/00 ,  A63B21/06 ,  A61H3/00 ,  A61H1/02

CPC分类号： A63B71/06 ,  A61B5/0205 ,  A61B5/0456 ,  A61B5/1118 ,  A61H1/0255 ,  A61H1/0274 ,  A61H3/00 ,  A61H2201/1633 ,  A61H2201/1642 ,  A61H2201/5015 ,  A61H2201/5064 ,  A61H2201/5071 ,  A61H2201/5084 ,  A61H2201/5092 ,  A61H2201/5097 ,  A61H2230/045 ,  A61H2230/065 ,  A61H2230/208 ,  A61H2230/305 ,  A61H2230/42 ,  A61H2230/50 ,  A61H2230/60 ,  A61H2230/805 ,  A63B15/00 ,  A63B21/002 ,  A63B21/0023 ,  A63B21/06 ,  A63B22/0023 ,  A63B22/0056 ,  A63B22/0076 ,  A63B22/0235 ,  A63B22/0605 ,  A63B22/0664 ,  A63B23/1218 ,  A63B23/1236 ,  A63B24/0062 ,  A63B24/0075 ,  A63B24/0087 ,  A63B69/0028 ,  A63B71/0686 ,  A63B2024/0093 ,  A63B2024/0096 ,  A63B2071/0625 ,  A63B2071/0655 ,  A63B2071/0663 ,  A63B2220/10 ,  A63B2220/17 ,  A63B2220/30 ,  A63B2220/40 ,  A63B2220/56 ,  A63B2220/805 ,  A63B2220/806 ,  A63B2220/833 ,  A63B2220/836 ,  A63B2220/89 ,  A63B2225/50 ,  A63B2225/54 ,  A63B2230/045 ,  A63B2230/062 ,  A63B2230/207 ,  A63B2230/425 ,  A63B2230/50 ,  A63B2230/60 ,  A63B2230/75 ,  A63B2244/20 ,  G06F19/00 ,  G06F19/3481 ,  G09B19/00 ,  G09B19/0038 ,  G09B23/288 ,  G16H20/30

摘要： Described herein are methods for determining a target musculoskeletal activity cycle (MSKC) to cardiac cycle (CC) timing relationship. The method may include detecting a first characteristic of a signal responsive to a CC timing of a user that repeats at a frequency that corresponds to a heart rate of the user; detecting a second characteristic of a signal responsive to a rhythmic musculoskeletal cycle activity (MSKC) timing of the user that repeats at a frequency that corresponds to the MSKC rate of the user; determining a value representative of an actual timing relationship between the first characteristic and the second characteristic; detecting a third characteristic of a signal corresponding to a physiological metric that varies with the actual timing relationship between the first and second characteristics; and determining a target value representative of a preferred timing relationship between the first and second characteristics.

公开(公告)号：US09707466B2

公开(公告)日：2017-07-18

申请号：US15384268

申请日：2016-12-19

申请人： Pulson, Inc.

发明人： Jeffery L. Bleich ,  Paul Mannheimer

IPC分类号： A63B71/06 ,  G09B19/00 ,  A63B22/00 ,  A63B22/02 ,  A63B22/06 ,  A63B24/00 ,  A63B69/00 ,  A61B5/0205 ,  A61B5/0456 ,  A61B5/11 ,  G06F19/00

CPC分类号： A63B71/06 ,  A61B5/0205 ,  A61B5/0456 ,  A61B5/1118 ,  A61H1/0255 ,  A61H1/0274 ,  A61H3/00 ,  A61H2201/1633 ,  A61H2201/1642 ,  A61H2201/5015 ,  A61H2201/5064 ,  A61H2201/5071 ,  A61H2201/5084 ,  A61H2201/5092 ,  A61H2201/5097 ,  A61H2230/045 ,  A61H2230/065 ,  A61H2230/208 ,  A61H2230/305 ,  A61H2230/42 ,  A61H2230/50 ,  A61H2230/60 ,  A61H2230/805 ,  A63B15/00 ,  A63B21/002 ,  A63B21/0023 ,  A63B21/06 ,  A63B22/0023 ,  A63B22/0056 ,  A63B22/0076 ,  A63B22/0235 ,  A63B22/0605 ,  A63B22/0664 ,  A63B23/1218 ,  A63B23/1236 ,  A63B24/0062 ,  A63B24/0075 ,  A63B24/0087 ,  A63B69/0028 ,  A63B71/0686 ,  A63B2024/0093 ,  A63B2024/0096 ,  A63B2071/0625 ,  A63B2071/0655 ,  A63B2071/0663 ,  A63B2220/10 ,  A63B2220/17 ,  A63B2220/30 ,  A63B2220/40 ,  A63B2220/56 ,  A63B2220/805 ,  A63B2220/806 ,  A63B2220/833 ,  A63B2220/836 ,  A63B2220/89 ,  A63B2225/50 ,  A63B2225/54 ,  A63B2230/045 ,  A63B2230/062 ,  A63B2230/207 ,  A63B2230/425 ,  A63B2230/50 ,  A63B2230/60 ,  A63B2230/75 ,  A63B2244/20 ,  G06F19/00 ,  G06F19/3481 ,  G09B19/00 ,  G09B19/0038 ,  G09B23/288 ,  G16H20/30

摘要： Described herein are methods for determining a target musculoskeletal activity cycle (MSKC) to cardiac cycle (CC) timing relationship. The method may include detecting a first characteristic of a signal responsive to a CC timing of a user that repeats at a frequency that corresponds to a heart rate of the user; detecting a second characteristic of a signal responsive to a rhythmic musculoskeletal cycle activity (MSKC) timing of the user that repeats at a frequency that corresponds to the MSKC rate of the user; determining a value representative of an actual timing relationship between the first characteristic and the second characteristic; detecting a third characteristic of a signal corresponding to a physiological metric that varies with the actual timing relationship between the first and second characteristics; and determining a target value representative of a preferred timing relationship between the first and second characteristics.

公开(公告)号：US11311732B2

公开(公告)日：2022-04-26

申请号：US16719605

申请日：2019-12-18

申请人： Pulson, Inc.

发明人： Jeffery L. Bleich ,  Paul Mannheimer ,  Darin Howard Buxbaum

IPC分类号： A61N1/365

摘要： The present invention is generally directed to methods, systems, and computer program products for coordinating musculoskeletal and cardiovascular hemodynamics. In some embodiments, a heart pacing signal causes heart contractions to occur with an essentially constant time relationship with respect to rhythmic musculoskeletal activity. In other embodiments, prompts (e.g., audio, graphical, etc.) are provided to a user to assist them in timing of their rhythmic musculoskeletal activity relative to timing of their cardiovascular cycle. In further embodiments, accurately indicating a heart condition during a cardiac stress test is increased.

公开(公告)号：US20170014633A1

公开(公告)日：2017-01-19

申请号：US15278617

申请日：2016-09-28

申请人： Pulson, Inc.

发明人： Jeffery L. Bleich ,  Paul Mannheimer ,  Darin Howard Buxbaum

IPC分类号： A61N1/365

CPC分类号： A61N1/36585 ,  A61N1/36507 ,  A61N1/36542

摘要： The present invention is generally directed to methods, systems, and computer program products for coordinating musculoskeletal and cardiovascular hemodynamics. In some embodiments, a heart pacing signal causes heart contractions to occur with an essentially constant time relationship with respect to rhythmic musculoskeletal activity. In other embodiments, prompts (e.g., audio, graphical, etc.) are provided to a user to assist them in timing of their rhythmic musculoskeletal activity relative to timing of their cardiovascular cycle. In further embodiments, accurately indicating a heart condition during a cardiac stress test is increased.

摘要翻译： 本发明一般涉及用于协调肌肉骨骼和心血管血液动力学的方法，系统和计算机程序产品。 在一些实施方案中，心脏起搏信号使心脏收缩以与节律性肌肉骨骼活性基本恒定的时间关系发生。 在其他实施例中，向用户提供提示（例如，音频，图形等）以帮助他们相对于其心血管周期的时间来定时调整其节奏的肌肉骨骼活动。 在另外的实施例中，精确指示心脏压力测试期间的心脏状况增加。

公开(公告)号：US09522317B2

公开(公告)日：2016-12-20

申请号：US14553732

申请日：2014-11-25

申请人： Pulson, Inc.

发明人： Jeffery L. Bleich ,  Paul D. Mannheimer

IPC分类号： A63B71/06 ,  A61B5/0205 ,  A61B5/11 ,  A61B5/0456 ,  A63B15/00 ,  A63B24/00 ,  G09B19/00 ,  G09B23/28 ,  A63B69/00 ,  A61H1/02 ,  A61H3/00 ,  A63B21/002 ,  A63B21/06 ,  A63B22/00 ,  A63B22/02 ,  A63B22/06 ,  A63B23/12

CPC分类号： A63B71/06 ,  A61B5/0205 ,  A61B5/0456 ,  A61B5/1118 ,  A61H1/0255 ,  A61H1/0274 ,  A61H3/00 ,  A61H2201/1633 ,  A61H2201/1642 ,  A61H2201/5015 ,  A61H2201/5064 ,  A61H2201/5071 ,  A61H2201/5084 ,  A61H2201/5092 ,  A61H2201/5097 ,  A61H2230/045 ,  A61H2230/065 ,  A61H2230/208 ,  A61H2230/305 ,  A61H2230/42 ,  A61H2230/50 ,  A61H2230/60 ,  A61H2230/805 ,  A63B15/00 ,  A63B21/002 ,  A63B21/0023 ,  A63B21/06 ,  A63B22/0023 ,  A63B22/0056 ,  A63B22/0076 ,  A63B22/0235 ,  A63B22/0605 ,  A63B22/0664 ,  A63B23/1218 ,  A63B23/1236 ,  A63B24/0062 ,  A63B24/0075 ,  A63B24/0087 ,  A63B69/0028 ,  A63B71/0686 ,  A63B2024/0093 ,  A63B2024/0096 ,  A63B2071/0625 ,  A63B2071/0655 ,  A63B2071/0663 ,  A63B2220/10 ,  A63B2220/17 ,  A63B2220/30 ,  A63B2220/40 ,  A63B2220/56 ,  A63B2220/805 ,  A63B2220/806 ,  A63B2220/833 ,  A63B2220/836 ,  A63B2220/89 ,  A63B2225/50 ,  A63B2225/54 ,  A63B2230/045 ,  A63B2230/062 ,  A63B2230/207 ,  A63B2230/425 ,  A63B2230/50 ,  A63B2230/60 ,  A63B2230/75 ,  A63B2244/20 ,  G06F19/00 ,  G06F19/3481 ,  G09B19/00 ,  G09B19/0038 ,  G09B23/288 ,  G16H20/30

摘要： Described herein are methods for determining a target musculoskeletal activity cycle (MSKC) to cardiac cycle (CC) timing relationship. The method may include detecting a first characteristic of a signal responsive to a CC timing of a user that repeats at a frequency that corresponds to a heart rate of the user; detecting a second characteristic of a signal responsive to a rhythmic musculoskeletal cycle activity (MSKC) timing of the user that repeats at a frequency that corresponds to the MSKC rate of the user; determining a value representative of an actual timing relationship between the first characteristic and the second characteristic; detecting a third characteristic of a signal corresponding to a physiological metric that varies with the actual timing relationship between the first and second characteristics; and determining a target value representative of a preferred timing relationship between the first and second characteristics.

摘要翻译： 本文描述了用于确定目标肌肉骨骼活动循环（MSKC）至心脏周期（CC）时间关系的方法。 该方法可以包括响应于以对应于用户的心率的频率重复的用户的CC定时来检测信号的第一特性; 检测响应于以对应于用户的MSKC速率的频率重复的用户的节奏肌肉骨骼周期活动（MSKC）定时的信号的第二特征; 确定表示所述第一特性和所述第二特性之间的实际定时关系的值; 检测对应于根据所述第一和第二特征之间的实际定时关系而变化的生理度量的信号的第三特性; 以及确定表示所述第一和第二特征之间的优选时间关系的目标值。

公开(公告)号：US10702759B2

公开(公告)日：2020-07-07

申请号：US16550587

申请日：2019-08-26

申请人： Pulson, Inc.

发明人： Jeffery L. Bleich ,  Paul Mannheimer

IPC分类号： A63B71/06 ,  A61B5/11 ,  A61B5/0205 ,  G09B19/00 ,  A63B24/00 ,  G09B23/28 ,  A61B5/0456 ,  G16H20/30 ,  A61B5/026 ,  A61B5/00 ,  G16H50/30 ,  A61B5/024 ,  A63B21/002 ,  A63B23/12 ,  A63B22/06 ,  A63B22/02 ,  A63B22/00 ,  A63B21/06 ,  A63B15/00 ,  A61H3/00 ,  A61H1/02 ,  A63B69/00

摘要： Described herein are methods for determining a target musculoskeletal activity cycle (MSKC) to cardiac cycle (CC) timing relationship. The method may include detecting a signal responsive to a cyclically-varying arterial blood flow at a location on a head of a user; providing a recurrent prompt at a frequency of the heart pump cycle using the signal, such that the signal correlates with a magnitude of blood flow adjacent to the location, and the recurrent prompt is provided to guide the user to time performance of a component of a rhythmic musculoskeletal activity with the recurrent prompt; and guiding the user to adjust a timing of the component of the rhythmic musculoskeletal activity to substantially maximize a magnitude of the signal. In some embodiments, the method further includes generating the recurrent prompt by amplifying the sound generated by the blood flow in or in proximity to an ear of the user.

公开(公告)号：US10512780B2

公开(公告)日：2019-12-24

申请号：US15877320

申请日：2018-01-22

申请人： Pulson, Inc.

发明人： Jeffery L. Bleich ,  Paul Mannheimer ,  Darin Howard Buxbaum

IPC分类号： A61N1/365

摘要： The present invention is generally directed to methods, systems, and computer program products for coordinating musculoskeletal and cardiovascular hemodynamics. In some embodiments, a heart pacing signal causes heart contractions to occur with an essentially constant time relationship with respect to rhythmic musculoskeletal activity. In other embodiments, prompts (e.g., audio, graphical, etc.) are provided to a user to assist them in timing of their rhythmic musculoskeletal activity relative to timing of their cardiovascular cycle. In further embodiments, accurately indicating a heart condition during a cardiac stress test is increased.

公开(公告)号：US20170095721A1

公开(公告)日：2017-04-06

申请号：US15384268

申请日：2016-12-19

申请人： Pulson, Inc.

发明人： Jeffery L. Bleich ,  Paul Mannheimer

IPC分类号： A63B71/06 ,  A63B22/00 ,  A63B22/02 ,  A63B22/06 ,  G06F19/00 ,  A63B69/00 ,  A61B5/0205 ,  A61B5/0456 ,  A61B5/11 ,  G09B19/00 ,  A63B24/00

CPC分类号： A63B71/06 ,  A61B5/0205 ,  A61B5/0456 ,  A61B5/1118 ,  A61H1/0255 ,  A61H1/0274 ,  A61H3/00 ,  A61H2201/1633 ,  A61H2201/1642 ,  A61H2201/5015 ,  A61H2201/5064 ,  A61H2201/5071 ,  A61H2201/5084 ,  A61H2201/5092 ,  A61H2201/5097 ,  A61H2230/045 ,  A61H2230/065 ,  A61H2230/208 ,  A61H2230/305 ,  A61H2230/42 ,  A61H2230/50 ,  A61H2230/60 ,  A61H2230/805 ,  A63B15/00 ,  A63B21/002 ,  A63B21/0023 ,  A63B21/06 ,  A63B22/0023 ,  A63B22/0056 ,  A63B22/0076 ,  A63B22/0235 ,  A63B22/0605 ,  A63B22/0664 ,  A63B23/1218 ,  A63B23/1236 ,  A63B24/0062 ,  A63B24/0075 ,  A63B24/0087 ,  A63B69/0028 ,  A63B71/0686 ,  A63B2024/0093 ,  A63B2024/0096 ,  A63B2071/0625 ,  A63B2071/0655 ,  A63B2071/0663 ,  A63B2220/10 ,  A63B2220/17 ,  A63B2220/30 ,  A63B2220/40 ,  A63B2220/56 ,  A63B2220/805 ,  A63B2220/806 ,  A63B2220/833 ,  A63B2220/836 ,  A63B2220/89 ,  A63B2225/50 ,  A63B2225/54 ,  A63B2230/045 ,  A63B2230/062 ,  A63B2230/207 ,  A63B2230/425 ,  A63B2230/50 ,  A63B2230/60 ,  A63B2230/75 ,  A63B2244/20 ,  G06F19/00 ,  G06F19/3481 ,  G09B19/00 ,  G09B19/0038 ,  G09B23/288 ,  G16H20/30

摘要： Described herein are methods for determining a target musculoskeletal activity cycle (MSKC) to cardiac cycle (CC) timing relationship. The method may include detecting a first characteristic of a signal responsive to a CC timing of a user that repeats at a frequency that corresponds to a heart rate of the user; detecting a second characteristic of a signal responsive to a rhythmic musculoskeletal cycle activity (MSKC) timing of the user that repeats at a frequency that corresponds to the MSKC rate of the user; determining a value representative of an actual timing relationship between the first characteristic and the second characteristic; detecting a third characteristic of a signal corresponding to a physiological metric that varies with the actual timing relationship between the first and second characteristics; and determining a target value representative of a preferred timing relationship between the first and second characteristics.

公开(公告)号：US11253766B2

公开(公告)日：2022-02-22

申请号：US16921405

申请日：2020-07-06

申请人： Pulson, Inc.

发明人： Jeffery L. Bleich ,  Paul Mannheimer

IPC分类号： A63B71/06 ,  A61B5/11 ,  A61B5/0205 ,  G09B19/00 ,  A63B24/00 ,  G09B23/28 ,  G16H20/30 ,  A61B5/026 ,  A61B5/00 ,  G16H50/30 ,  A61B5/024 ,  A61B5/352 ,  A63B21/002 ,  A63B23/12 ,  A63B22/06 ,  A63B22/02 ,  A63B22/00 ,  A63B21/06 ,  A63B15/00 ,  A61H3/00 ,  A61H1/02 ,  A63B69/00

摘要： Described herein are methods for determining a target musculoskeletal activity cycle (MSKC) to cardiac cycle (CC) timing relationship. The method may include detecting a signal responsive to a cyclically-varying arterial blood flow at a location on a head of a user; providing a recurrent prompt at a frequency of the heart pump cycle using the signal, such that the signal correlates with a magnitude of blood flow adjacent to the location, and the recurrent prompt is provided to guide the user to time performance of a component of a rhythmic musculoskeletal activity with the recurrent prompt; and guiding the user to adjust a timing of the component of the rhythmic musculoskeletal activity to substantially maximize a magnitude of the signal. In some embodiments, the method further includes generating the recurrent prompt by amplifying the sound generated by the blood flow in or in proximity to an ear of the user.