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1.发明申请公开(公告)号：US20110270238A1
公开(公告)日：2011-11-03
申请号：US12980952
申请日：2010-12-29
申请人： Raed Rizq , Dave Sogard , Roger Hastings
发明人： Raed Rizq , Dave Sogard , Roger Hastings
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B2018/0022 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61B2018/0212 , A61B2018/0262
摘要： A cryotherapy balloon catheter includes a compliant cryotherapy balloon comprising a distal balloon section dimensioned for placement within a renal artery and a proximal balloon section dimensioned to abut against an ostium of the renal artery and extend into at least a portion of the abdominal aorta. The compliant balloon has a diameter that varies non-uniformly along a length of the compliant balloon, such that a diameter at the proximal balloon section is larger than a diameter of the distal balloon section. The cryotherapy balloon catheter may be configured to deliver cryogenic therapy to at least the ostium of the renal artery sufficient to irreversibly terminate renal sympathetic nerve activity, such as by causing neurotmesis of renal nerve fibers and ganglia at the ostium of the renal artery.
摘要翻译： 冷冻治疗气囊导管包括顺应性冷冻治疗气囊，其包括尺寸适于放置在肾动脉内的远端球囊部分和近端球囊部分，其近似球囊部分的尺寸设置成抵靠肾动脉的口并且延伸到腹主动脉的至少一部分。 顺应性球囊具有沿着柔顺气囊的长度不均匀地变化的直径，使得近端球囊部分处的直径大于远端球囊部分的直径。 冷冻治疗气球导管可以被配置为将低温治疗递送至至少肾动脉的口，足以不可逆地终止肾交感神经活动，例如通过在肾动脉的口处引起肾神经纤维和神经节的神经痛。
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公开(公告)号：US20110263921A1
公开(公告)日：2011-10-27
申请号：US12980972
申请日：2010-12-29
申请人： Anthony Vrba , Dave Sogard , Raed Rizq , Dominic Allocco , Michael Gerdts , Gordon Kocur , Steve Kangas
发明人： Anthony Vrba , Dave Sogard , Raed Rizq , Dominic Allocco , Michael Gerdts , Gordon Kocur , Steve Kangas
CPC分类号： A61B18/18 , A61B18/02 , A61B18/04 , A61B18/20 , A61B18/24 , A61B2018/00023 , A61B2018/0022 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/0212 , A61B2018/0281 , A61B2018/046 , A61B2018/1861 , A61N5/1002 , A61N7/022 , A61N2007/003
摘要： A renal denervation apparatus includes a treatment element dimensioned for deployment on or within a renal artery of a patient. The treatment element comprises a predefined pattern arranged to complete at least one revolution of the treatment element. The apparatus includes a treatment source. The treatment source and treatment element are configured to cooperatively facilitate communication of an agent from the treatment source to the pattern arrangement of the treatment element. The treatment element is configured to deliver denervation therapy using the agent via the pattern arrangement to one or more regions of the renal artery adjacent the pattern arrangement, such that at least one complete revolution of the renal artery is subjected to the denervation therapy.
摘要翻译： 肾去神经支配装置包括用于部署在患者的肾动脉上或内部的治疗元件。 治疗元件包括布置成完成治疗元件的至少一圈的预定图案。 该装置包括处理源。 处理源和处理元件被配置为协同地促进试剂从处理源到处理元件的图案布置的连通。 治疗元件被配置为使用所述药剂经由图案布置将去神经治疗递送到与所述图案布置相邻的所述肾动脉的一个或多个区域，使得对所述肾动脉的至少一个完整的转动进行去神经支配治疗。
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公开(公告)号：US08562566B2
公开(公告)日：2013-10-22
申请号：US11068330
申请日：2005-02-28
IPC分类号： A61M5/178
CPC分类号： A61F2/95 , A61M2025/0188
摘要： A system for controlling multiple guidewires comprises a guiderail, which has a housing that defines a first guidewire lumen and a second guidewire lumen. The guidewire lumens extend through the entire length of the guiderail. The guiderail housing further defines a first longitudinal opening that extends from the first guidewire lumen to the exterior of the guiderail, and a second longitudinal opening that extends from the second guidewire lumen to the exterior of the guiderail.
摘要翻译： 一种用于控制多条导线的系统包括一个导轨，其具有限定第一导丝管腔和第二导丝管腔的外壳。 导丝流道延伸穿过导轨的整个长度。 导轨壳体进一步限定了从第一导丝内腔延伸到导轨外部的第一纵向开口，以及从第二导丝管腔延伸到导轨外部的第二纵向开口。
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公开(公告)号：US20090118818A1
公开(公告)日：2009-05-07
申请号：US11934296
申请日：2007-11-02
申请人： Aaron Foss , Raed Rizq , Daniel Vancamp
发明人： Aaron Foss , Raed Rizq , Daniel Vancamp
CPC分类号： A61L31/088 , A61L31/14
摘要： An endoprosthesis such as a coronary stent includes a surface region that defines a depression in the form of a channel, the depression having an interior surface, and an enhanced roughness on the interior surface.
摘要翻译： 诸如冠状动脉支架的内假体包括限定通道形式的凹陷的表面区域，凹陷具有内表面，并且在内表面上具有增强的粗糙度。
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公开(公告)号：US08795228B2
公开(公告)日：2014-08-05
申请号：US13462231
申请日：2012-05-02
CPC分类号： A61M25/1011 , A61M25/10 , A61M2025/1013 , A61M2025/105 , A61M2025/1081 , A61M2025/1086
摘要： A drug eluting balloon device is disclosed, comprising a balloon and a sheath disposed around the balloon, the sheath comprising a plurality of drug delivery areas. When the sheath is in a first position, the drug delivery areas are in the form of pockets adapted to contain a therapeutic agent. When the sheath is expanded, the pockets invert into protrusions in order to deliver the therapeutic agent. In an alternative embodiment, the pockets are adapted to be pushed outwardly upon inflation of the balloon. The device may further comprise a fluid or shape memory material to force the pockets outwardly.
摘要翻译： 公开了一种药物洗脱球囊装置，包括球囊和围绕球囊设置的护套，护套包括多个药物递送区域。 当护套处于第一位置时，药物输送区域为适于容纳治疗剂的口袋形式。 当护套膨胀时，口袋转入突起以递送治疗剂。 在替代实施例中，袋子适于在气囊膨胀时向外推动。 该装置可以进一步包括流体或形状记忆材料以将凹穴向外强制。
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6.发明申请公开(公告)号：US20060142834A1
公开(公告)日：2006-06-29
申请号：US11022585
申请日：2004-12-23
申请人： Raed Rizq , John Chen , Stanley Nordin
发明人： Raed Rizq , John Chen , Stanley Nordin
IPC分类号： A61F2/06
CPC分类号： A61M25/1027 , A61F2/958 , A61F2002/9583 , A61M2025/1088
摘要： In an assembly of a balloon mounted on a catheter and a stent mounted over the deflated balloon, the balloon is provided with a fugitive plasticizer before the stent is crimped over the balloon. The fugitive plasticizer can soften the balloon surface so that molding of the balloon surface to conform to the crimped stent occurs. The fugitive plasticizer is removed before the assembly is used.
摘要翻译： 在安装在导管和安装在放气气球上的支架上的气囊的组件中，气囊在支架被压接在气囊之前设置有缓冲增塑剂。 短促增塑剂可以软化球囊表面，从而发生球囊表面的模制以符合卷曲的支架。 在使用组装之前，除去挥发性增塑剂。
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7.发明授权公开(公告)号：US09586030B2
公开(公告)日：2017-03-07
申请号：US11022585
申请日：2004-12-23
申请人： Raed Rizq , John J. Chen , Stanley Nordin
发明人： Raed Rizq , John J. Chen , Stanley Nordin
CPC分类号： A61M25/1027 , A61F2/958 , A61F2002/9583 , A61M2025/1088
摘要： In an assembly of a balloon mounted on a catheter and a stent mounted over the deflated balloon, the balloon is provided with a fugitive plasticizer before the stent is crimped over the balloon. The fugitive plasticizer can soften the balloon surface so that molding of the balloon surface to conform to the crimped stent occurs. The fugitive plasticizer is removed before the assembly is used.
摘要翻译： 在安装在导管和安装在放气气球上的支架上的气囊的组件中，气囊在支架被压接在气囊之前设置有缓冲增塑剂。 短促增塑剂可以软化球囊表面，从而发生球囊表面的模制以符合卷曲的支架。 在使用组装之前，除去挥发性增塑剂。
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公开(公告)号：US20090227949A1
公开(公告)日：2009-09-10
申请号：US12399548
申请日：2009-03-06
申请人： David Knapp , Timothy J. Mickley , John Chen , Derek Sutermeister , Toby Freyman , Gordon Kocur , Daniel Horn , Jim Anderson , Ben Arcand , Jay Rassat , Raed Rizq , Irina Nazarova , Dan Quillin , Jan Weber , Torsten Scheuermann
发明人： David Knapp , Timothy J. Mickley , John Chen , Derek Sutermeister , Toby Freyman , Gordon Kocur , Daniel Horn , Jim Anderson , Ben Arcand , Jay Rassat , Raed Rizq , Irina Nazarova , Dan Quillin , Jan Weber , Torsten Scheuermann
IPC分类号： A61M25/10
CPC分类号： A61M25/1029 , A61L29/085 , A61L29/16 , A61L2300/416 , A61M25/0045 , A61M25/10 , A61M2025/0056 , A61M2025/1031 , A61M2025/105 , B29L2009/005 , C08L53/02
摘要： Catheter devices having an expandable balloon for delivering a therapeutic agent to a body site. The balloon has one or more folds which serve as a reservoir for containing the therapeutic agent. The fold may have any of various configurations to hold the therapeutic agent. In some cases, the balloon comprises one or more lobes that forms the fold(s). The therapeutic agent may be provided in various ways. For example, the therapeutic agent may be contained in packets that rupture upon expansion of the balloon, or as a plurality of discrete bulk masses, or sealed within compartments.
摘要翻译： 具有用于将治疗剂递送到身体部位的可膨胀气囊的导管装置。 气囊具有一个或多个折叠，其用作容纳治疗剂的储存器。 折叠可以具有保持治疗剂的各种构造中的任何一种。 在一些情况下，气囊包括形成褶皱的一个或多个凸起。 治疗剂可以以各种方式提供。 例如，治疗剂可以包含在囊膨胀时破裂的包装中，或者作为多个离散的体积块，或者密封在隔室内。
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公开(公告)号：US07343659B2
公开(公告)日：2008-03-18
申请号：US10192253
申请日：2002-07-10
申请人： Jan Weber , Raed Rizq , Fernando DiCaprio
发明人： Jan Weber , Raed Rizq , Fernando DiCaprio
CPC分类号： A61F2/95 , A61F2/958 , A61F2002/9522 , A61F2250/0067 , Y10T29/49803 , Y10T29/49927 , Y10T29/49929
摘要： A method of making a medical device includes compressing a prosthesis, e.g., a therapeutic agent-carrying stent or stent-graft, to a catheter without contacting an outer surface of the prosthesis, e.g., by electromagnetically compressing the prosthesis.
摘要翻译： 制造医疗装置的方法包括例如通过电磁地压缩假体将假体（例如带有治疗剂的支架或支架移植物）压缩到导管而不接触假体的外表面。
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10.发明授权Medical devices including a magnetically activatable body or portion for treatment 失效医疗装置包括可激活的身体或用于治疗的部分公开(公告)号：US07172622B2
公开(公告)日：2007-02-06
申请号：US10283815
申请日：2002-10-30
IPC分类号： A61F2/06
CPC分类号： A61M25/0127 , A61F2/95 , A61F2002/9505 , A61F2210/009 , H01F1/0308
摘要： A medical device including an insertable body which is insertable into a body lumen or cavity. The insertable body of the medical device includes a magnetically activatable body portion to magnetically induce a dimension change to effect treatment.
摘要翻译： 一种医疗装置，包括可插入体腔或腔内的可插入体。 医疗装置的可插入体包括磁性可激活的主体部分，以磁性地引起尺寸变化以实现治疗。
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