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公开(公告)号：US20090171590A1
公开(公告)日：2009-07-02
申请号：US12276277
申请日：2008-11-21
申请人： Robert PUSKAS , Richard A. Livingston , Douglas D. Held , Barbara Klein , Neolle Fukushima , Robert Freese , Philippe J. Goix , Peter R. David , Mickey Urdea
发明人： Robert PUSKAS , Richard A. Livingston , Douglas D. Held , Barbara Klein , Neolle Fukushima , Robert Freese , Philippe J. Goix , Peter R. David , Mickey Urdea
IPC分类号： G06F19/00
CPC分类号： G01N35/1095 , G01N1/28 , G01N15/1459 , G01N21/6428 , G01N27/447 , G01N33/68 , G01N33/6803 , G01N33/6845 , G01N2015/1438 , G01N2035/1034
摘要： The invention encompasses analyzers and analyzer systems that include a single particle analyzer, methods of using the analyzers and analyzers systems to analyze samples, either for single particles or for multiple particles (multiplexing), methods of doing business based on the use of the analyzers or analyzer systems of the system, and electronic media for storing parameters useful in the analyzers and analyzer systems of the invention.
摘要翻译： 本发明包括分析仪和分析仪系统，其包括单个粒子分析仪，使用分析仪和分析仪系统来分析样品的单颗粒或多颗粒（多路复用）的方法，基于使用分析仪进行生意的方法或 系统的分析器系统和用于存储在本发明的分析器和分析器系统中有用的参数的电子介质。
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公开(公告)号：US20080158543A1
公开(公告)日：2008-07-03
申请号：US11838114
申请日：2007-08-13
申请人： Robert Puskas , Richard A. Livingston , Douglas D. Held , Barbara Klein , Noelle Fukushima , Robert Freese , Philippe J. Goix , Peter R. David , Mickey Urdea
发明人： Robert Puskas , Richard A. Livingston , Douglas D. Held , Barbara Klein , Noelle Fukushima , Robert Freese , Philippe J. Goix , Peter R. David , Mickey Urdea
CPC分类号： G01N35/1095 , G01N1/28 , G01N15/1459 , G01N21/6428 , G01N27/447 , G01N33/68 , G01N33/6803 , G01N33/6845 , G01N2015/1438 , G01N2035/1034
摘要： The invention encompasses analyzers and analyzer systems that include a single particle analyzer, methods of using the analyzers and analyzers systems to analyze samples, either for single particles or for multiple particles (multiplexing), methods of doing business based on the use of the analyzers or analyzer systems of the system, and electronic media for storing parameters useful in the analyzers and analyzer systems of the invention.
摘要翻译： 本发明包括分析仪和分析仪系统，其包括单个粒子分析仪，使用分析仪和分析仪系统来分析样品的单颗粒或多颗粒（多路复用）的方法，基于使用分析仪进行生意的方法或 系统的分析器系统和用于存储在本发明的分析器和分析器系统中有用的参数的电子介质。
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公开(公告)号：US20060078998A1
公开(公告)日：2006-04-13
申请号：US11048660
申请日：2005-01-28
申请人： Robert Puskas , Richard Livingston , Douglas Held , Barbara Klein , Noelle Fukushima , Robert Freese , Philippe Goix , Peter David , Mickey Urdea
发明人： Robert Puskas , Richard Livingston , Douglas Held , Barbara Klein , Noelle Fukushima , Robert Freese , Philippe Goix , Peter David , Mickey Urdea
IPC分类号： G01N24/00
CPC分类号： G01N35/1095 , G01N1/28 , G01N15/1459 , G01N21/6428 , G01N27/447 , G01N33/68 , G01N33/6803 , G01N33/6845 , G01N2015/1438 , G01N2035/1034
摘要： The invention encompasses analyzers and analyzer systems that include a single particle analyzer, methods of using the analyzers and analyzers systems to analyze samples, either for single particles or for multiple particles (multiplexing), methods of doing business based on the use of the analyzers or analyzer systems of the system, and electronic media for storing parameters useful in the analyzers and analyzer systems of the invention.
摘要翻译： 本发明包括分析仪和分析仪系统，其包括单个粒子分析仪，使用分析仪和分析仪系统来分析样品的单颗粒或多颗粒（多路复用）的方法，基于使用分析仪进行生意的方法或 系统的分析器系统和用于存储在本发明的分析器和分析器系统中有用的参数的电子介质。
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公开(公告)号：US20130286398A1
公开(公告)日：2013-10-31
申请号：US13456493
申请日：2012-04-26
摘要： Optical computing devices are disclosed. One optical computing device includes an electromagnetic radiation source that emits electromagnetic radiation into an optical train to optically interact with a sample and at least one integrated computational element, the sample being configured to generate optically interacted radiation. A sampling window is arranged adjacent the sample and configured to allow transmission of the electromagnetic radiation therethrough and has one or more surfaces that generate one or more stray signals. A first focal lens is arranged to receive the optically interacted radiation and the one or more stray signals and generate a primary focal point from the optically interacted radiation. A structural element defines a spatial aperture aligned with the primary focal point such that the optically interacted radiation is able to pass therethrough while transmission of the one or more stray signals is substantially blocked by the structural element.
摘要翻译： 公开了光学计算设备。 一个光学计算设备包括电磁辐射源，其将电磁辐射发射到光学系列中以与样品和至少一个集成的计算元件光学相互作用，所述样品被配置为产生光学相互作用的辐射。 采样窗口布置在样本附近并且被配置为允许电磁辐射通过其中并且具有产生一个或多个杂散信号的一个或多个表面。 布置第一焦点透镜以接收光学相互作用的辐射和一个或多个杂散信号，并从光学相互作用的辐射产生主要焦点。 结构元件限定与主焦点对准的空间孔，使得光学相互作用的辐射能够通过，其中一个或多个杂散信号的传输被结构元件基本上阻挡。
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5.发明申请Systems and methods for mastering microstructures through a substrate using negative photoresist and microstructure masters so produced 有权通过使用负性光致抗蚀剂和如此生产的微结构主体的基板来掌握微结构的系统和方法公开(公告)号：US20050058948A1
公开(公告)日：2005-03-17
申请号：US10661917
申请日：2003-09-11
申请人： Robert Freese , Thomas Rinehart , Robert Wood
发明人： Robert Freese , Thomas Rinehart , Robert Wood
CPC分类号： G02B3/0025 , B82Y10/00 , B82Y40/00 , G02B5/1857 , G03F7/0002 , G03F7/0005 , G03F7/0007 , G03F7/0015 , G03F7/2053 , G03F7/24
摘要： Microstructures are fabricated by impinging a radiation beam, such as a laser beam, through a substrate that is transparent to the laser beam, into a negative photoresist layer on the substrate. The negative photoresist layer may be subsequently developed to provide a master for optical and/or mechanical microstructures. Related systems, microstructure products and microstructure masters also are disclosed.
摘要翻译： 通过将诸如激光束的辐射束通过对激光束透明的衬底照射到衬底上的负光致抗蚀剂层中来制造微结构。 可以随后显影负性光致抗蚀剂层以提供用于光学和/或机械微结构的母版。 还公开了相关系统，微结构产品和微结构主体。
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6.发明授权公开(公告)号：US08941046B2
公开(公告)日：2015-01-27
申请号：US13456350
申请日：2012-04-26
CPC分类号： G01N21/17 , G01J2003/1226 , G01N21/274 , G01N21/31 , G01N2021/3137 , G01N2021/3174 , G06E3/001
摘要： Optical computing devices are disclosed. One exemplary optical computing device includes an electromagnetic radiation source configured to optically interact with a sample and first and second integrated computational elements arranged in primary and reference channels, respectively. The first and second integrated computational elements produce first and second modified electromagnetic radiations, and a detector is arranged to receive the first and second modified electromagnetic radiations and generate an output signal corresponding to the characteristic of the sample.
摘要翻译： 公开了光学计算设备。 一个示例性的光学计算设备包括被配置为与样本光学相互作用的电磁辐射源以及分别布置在主信道和参考信道中的第一和第二集成计算元件。 第一和第二集成计算元件产生第一和第二修改的电磁辐射，并且检测器被布置成接收第一和第二修改的电磁辐射并产生对应于样本的特性的输出信号。
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7.发明授权公开(公告)号：US08780352B2
公开(公告)日：2014-07-15
申请号：US13456379
申请日：2012-04-26
IPC分类号： G01N21/00
CPC分类号： G01N21/17 , G01J3/0294 , G01J3/28 , G01J2003/1226 , G01N21/274 , G01N21/31 , G01N2021/3137 , G01N2021/3174 , G06E3/001
摘要： Optical computing devices are disclosed. One exemplary optical computing device includes an electromagnetic radiation source configured to optically interact with a sample and first and second integrated computational elements arranged in primary and reference channels, respectively. The first and second integrated computational elements produce first and second modified electromagnetic radiations, and a detector is arranged to receive the first and second modified electromagnetic radiations and generate an output signal corresponding to the characteristic of the sample.
摘要翻译： 公开了光学计算设备。 一个示例性的光学计算设备包括被配置为与样本光学相互作用的电磁辐射源以及分别布置在主信道和参考信道中的第一和第二集成计算元件。 第一和第二集成计算元件产生第一和第二修改的电磁辐射，并且检测器被布置成接收第一和第二修改的电磁辐射并产生对应于样本的特性的输出信号。
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8.发明申请公开(公告)号：US20130284899A1
公开(公告)日：2013-10-31
申请号：US13456350
申请日：2012-04-26
IPC分类号： G01N21/17
CPC分类号： G01N21/17 , G01J2003/1226 , G01N21/274 , G01N21/31 , G01N2021/3137 , G01N2021/3174 , G06E3/001
摘要： Optical computing devices are disclosed. One exemplary optical computing device includes an electromagnetic radiation source configured to optically interact with a sample and first and second integrated computational elements arranged in primary and reference channels, respectively. The first and second integrated computational elements produce first and second modified electromagnetic radiations, and a detector is arranged to receive the first and second modified electromagnetic radiations and generate an output signal corresponding to the characteristic of the sample.
摘要翻译： 公开了光学计算设备。 一个示例性的光学计算设备包括被配置为与样本光学相互作用的电磁辐射源以及分别布置在主信道和参考信道中的第一和第二集成计算元件。 第一和第二集成计算元件产生第一和第二修改的电磁辐射，并且检测器被布置成接收第一和第二修改的电磁辐射并产生对应于样本的特性的输出信号。
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9.发明申请公开(公告)号：US20060275714A1
公开(公告)日：2006-12-07
申请号：US11465377
申请日：2006-08-17
申请人： Thomas Rinehart , Robert Wood , Robert Freese
发明人： Thomas Rinehart , Robert Wood , Robert Freese
IPC分类号： G02B3/00
CPC分类号： G02B3/0031 , G02B3/0012 , G02B3/0043 , G02B5/1857
摘要： Optical microstructures, such as microlenses, are fabricated by rotating a cylindrical platform that includes a radiation sensitive layer thereon, about its axis, while simultaneously axially rastering a laser beam across at least a portion of the radiation sensitive layer. The cylindrical platform is also simultaneously translated axially while it is being rotated. The amplitude of the laser beam is continuously varied while rastering. The optical microstructures that are imaged in the radiation sensitive layer can be developed to provide a master for replicating a microlenses.
摘要翻译： 诸如微透镜的光学微结构通过围绕其轴线旋转包括辐射敏感层的圆柱形平台来制造，同时沿着辐射敏感层的至少一部分轴向地扫描激光束。 圆柱形平台在旋转的同时也被轴向同时平移。 激光束的幅度连续变化。 可以开发在辐射敏感层中成像的光学微结构以提供用于复制微透镜的母版。
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10.发明授权公开(公告)号：US09019501B2
公开(公告)日：2015-04-28
申请号：US13456405
申请日：2012-04-26
IPC分类号： G01N21/59 , G01N21/17 , G01J3/02 , G01N21/27 , G01N21/31 , G06E3/00 , G02B5/28 , G01J3/12 , E21B47/10
CPC分类号： G01N21/17 , E21B47/102 , G01J3/0229 , G01J3/0294 , G01J2003/1226 , G01N21/274 , G01N21/31 , G01N2021/3137 , G01N2021/3174 , G02B5/28 , G06E3/001
摘要： Optical computing devices are disclosed. One exemplary optical computing device includes an electromagnetic radiation source configured to optically interact with a sample and first and second integrated computational elements arranged in primary and reference channels, respectively, the first and second computational elements are configured to be either positively or negatively correlated to the characteristic of the sample. The first and second integrated computational elements produce first and second modified electromagnetic radiations, and a detector is arranged to receive the first and second modified electromagnetic radiations and generate an output signal corresponding to the characteristic of the sample.
摘要翻译： 公开了光学计算设备。 一个示例性光学计算设备包括被配置为与样本光学相互作用的电磁辐射源以及分别布置在主信道和参考信道中的第一和第二集成计算元件，第一和第二计算元件被配置为与 样品的特征。 第一和第二集成计算元件产生第一和第二修改的电磁辐射，并且检测器被布置成接收第一和第二修改的电磁辐射并产生对应于样本的特性的输出信号。
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