公开(公告)号：US20150224500A1

公开(公告)日：2015-08-13

申请号：US14530857

申请日：2014-11-03

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Thorsten Brueckner ,  Peter Koltay ,  Norbert Oranth ,  Juergen Spinke ,  Laurent Tanguy

IPC: B01L3/00 ,  B01L5/00 ,  G01N35/10 ,  B01L1/00

CPC classification number: B01L3/52 ,  B01L1/00 ,  B01L3/523 ,  B01L5/00 ,  B01L2200/0684 ,  B01L2200/141 ,  B01L2300/048 ,  B01L2300/0681 ,  B01L2400/086 ,  G01N35/1002 ,  Y10T436/11

Abstract: A cartridge for dispensing a fluid is presented. The cartridge comprises a reservoir chamber for receiving the fluid and for receiving a ventilation gas. The reservoir chamber comprises an inlet for receiving the ventilation gas and an outlet for dispensing the fluid. At least a portion of the reservoir chamber is filled with the ventilation gas when in an operating position. The inlet is located in the portion being filled with the ventilation gas. The fluid comprises a reagent. The cartridge further comprises a baffle for restricting gas diffusion through the inlet. The reservoir chamber receives the ventilation gas via the baffle. The inlet is maintains a constant gas pressure within the portion of the reservoir chamber that is being filled with the ventilation gas.

Abstract translation: 呈现用于分配流体的盒。 墨盒包括用于接收流体并用于接收通气气体的储存室。 储存室包括用于接收通气气体的入口和用于分配流体的出口。 当处于操作位置时，储存室的至少一部分填充有通气气体。 入口位于填充有通气气体的部分中。 流体包含试剂。 墨盒还包括用于限制通过入口的气体扩散的挡板。 储存室通过挡板接收通气气体。 入口在储存室的被填充有通风气体的部分内保持恒定的气体压力。

公开(公告)号：US10252273B2

公开(公告)日：2019-04-09

申请号：US14530858

申请日：2014-11-03

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Stefan Borja Bammesberger ,  Sabrina Kartmann ,  Peter Koltay ,  Klaus Mutschler ,  Juergen Spinke ,  Laurent Tanguy

IPC: B01L3/00 ,  F16K99/00 ,  G01N35/00 ,  G01N35/10 ,  B01L3/02

Abstract: A valve for dispensing a fluid comprising a dry portion and a wet portion is presented. Only the wet portion is contacted by the fluid. The wet portion comprises a fluid dispenser unit having a inlet opening, a capillary nozzle providing a fluid outlet, a cavity, the capillary nozzle having an end within the cavity, and a plunger. The plunger moves within the cavity into an opening position allowing an inflow of the fluid through the inlet opening through the cavity and an outflow of the fluid through the capillary nozzle. The plunger has a sealing surface directed towards the end of the capillary nozzle. The plunger moves into a closing position for sealing the end of the capillary nozzle with the sealing surface. The dry portion comprises a closing component for exercising a magnetic closing force onto the plunger for attracting the plunger into the closing position.

公开(公告)号：US10466264B2

公开(公告)日：2019-11-05

申请号：US14530863

申请日：2014-11-03

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Stefan Borja Bammesberger ,  Andreas Ernst ,  Peter Koltay ,  Nadine Losleben ,  Laurent Tanguy

IPC: B01L3/02 ,  G01N35/10 ,  B05B17/06 ,  B05C5/02 ,  B05B1/02

Abstract: A dispensing assembly comprising a cartridge holder is presented. The cartridge holder can receive a cartridge for dispensing a fluid. The cartridge can comprise a reservoir for receiving the fluid. The reservoir can comprise an outlet. The reservoir can have an adjustable volume for forcing the fluid through the outlet. The cartridge can further comprise a nozzle for dispensing the fluid. The nozzle can be connected to the outlet. The dispensing assembly can further comprise an actuator for actuating the adjustable volume. The dispensing assembly can further comprise an impulse generator for imparting an impulse to the nozzle. The impulse generator can comprise an actor for contacting the nozzle. The dispenser assembly can further comprise a controller for controlling the actor and the impulse generator.

公开(公告)号：US09573131B2

公开(公告)日：2017-02-21

申请号：US14530857

申请日：2014-11-03

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Thorsten Brueckner ,  Peter Koltay ,  Norbert Oranth ,  Juergen Spinke ,  Laurent Tanguy

IPC: A61J1/06 ,  B01L3/00 ,  G01N1/10 ,  G01N35/10 ,  B01L1/00 ,  B01L5/00

CPC classification number: B01L3/52 ,  B01L1/00 ,  B01L3/523 ,  B01L5/00 ,  B01L2200/0684 ,  B01L2200/141 ,  B01L2300/048 ,  B01L2300/0681 ,  B01L2400/086 ,  G01N35/1002 ,  Y10T436/11

Abstract: A cartridge for dispensing a fluid is presented. The cartridge comprises a reservoir chamber for receiving the fluid and for receiving a ventilation gas. The reservoir chamber comprises an inlet for receiving the ventilation gas and an outlet for dispensing the fluid. At least a portion of the reservoir chamber is filled with the ventilation gas when in an operating position. The inlet is located in the portion being filled with the ventilation gas. The fluid comprises a reagent. The cartridge further comprises a baffle for restricting gas diffusion through the inlet. The reservoir chamber receives the ventilation gas via the baffle. The inlet is maintains a constant gas pressure within the portion of the reservoir chamber that is being filled with the ventilation gas.

Abstract translation: 呈现用于分配流体的盒。 墨盒包括用于接收流体并用于接收通气气体的储存室。 储存室包括用于接收通气气体的入口和用于分配流体的出口。 当处于操作位置时，储存室的至少一部分填充有通气气体。 入口位于填充有通气气体的部分中。 流体包含试剂。 墨盒还包括用于限制通过入口的气体扩散的挡板。 储存室通过挡板接收通气气体。 入口在储存室的被填充有通风气体的部分内保持恒定的气体压力。

公开(公告)号：US20150050186A1

公开(公告)日：2015-02-19

申请号：US14530858

申请日：2014-11-03

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Stefan Borja Bammesberger ,  Sabrina Kartmann ,  Peter Koltay ,  Klaus Mutschler ,  Juergen Spinke ,  Laurent Tanguy

IPC: B01L3/00 ,  F16K99/00

CPC classification number: B01L3/567 ,  B01L3/0265 ,  B01L3/52 ,  B01L2300/0838 ,  B01L2400/0666 ,  F16K99/0005 ,  F16K99/0042 ,  F16K2099/0084 ,  G01N35/0099 ,  G01N35/1002 ,  G01N35/1016 ,  G01N2035/1034

Abstract: A valve for dispensing a fluid comprising a dry portion and a wet portion is presented. Only the wet portion is contacted by the fluid. The wet portion comprises a fluid dispenser unit having a inlet opening, a capillary nozzle providing a fluid outlet, a cavity, the capillary nozzle having an end within the cavity, and a plunger. The plunger moves within the cavity into an opening position allowing an inflow of the fluid through the inlet opening through the cavity and an outflow of the fluid through the capillary nozzle. The plunger has a sealing surface directed towards the end of the capillary nozzle. The plunger moves into a closing position for sealing the end of the capillary nozzle with the sealing surface. The dry portion comprises a closing component for exercising a magnetic closing force onto the plunger for attracting the plunger into the closing position.

Abstract translation: 提出了一种用于分配包括干燥部分和湿部分的流体的阀。 只有湿部分被流体接触。 湿部分包括具有入口开口的流体分配器单元，提供流体出口的毛细管嘴，空腔，毛细管喷嘴在腔内具有一端，以及柱塞。 柱塞在空腔内移动到打开位置，允许流体通过入口通过空腔流入，流体通过毛细管喷嘴流出。 柱塞具有指向毛细管喷嘴端部的密封表面。 柱塞移动到关闭位置，以用密封表面密封毛细管嘴的端部。 所述干燥部分包括关闭部件，用于对所述柱塞施加磁力关闭力，以将所述柱塞吸引到所述关闭位置。