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    CARTRIDGE FOR DISPENSING A FLUID COMPRISING A REAGENT
    4.
    发明申请
    CARTRIDGE FOR DISPENSING A FLUID COMPRISING A REAGENT 有权
    用于分配包含试剂的流体的盒

    公开(公告)号：US20150224500A1

    公开(公告)日：2015-08-13

    申请号：US14530857

    申请日：2014-11-03

    Applicant: Roche Diagnostics Operations, Inc.

    Inventor： Thorsten Brueckner ,  Peter Koltay ,  Norbert Oranth ,  Juergen Spinke ,  Laurent Tanguy

    IPC: B01L3/00 ,  B01L5/00 ,  G01N35/10 ,  B01L1/00

    CPC classification number: B01L3/52 ,  B01L1/00 ,  B01L3/523 ,  B01L5/00 ,  B01L2200/0684 ,  B01L2200/141 ,  B01L2300/048 ,  B01L2300/0681 ,  B01L2400/086 ,  G01N35/1002 ,  Y10T436/11

    Abstract: A cartridge for dispensing a fluid is presented. The cartridge comprises a reservoir chamber for receiving the fluid and for receiving a ventilation gas. The reservoir chamber comprises an inlet for receiving the ventilation gas and an outlet for dispensing the fluid. At least a portion of the reservoir chamber is filled with the ventilation gas when in an operating position. The inlet is located in the portion being filled with the ventilation gas. The fluid comprises a reagent. The cartridge further comprises a baffle for restricting gas diffusion through the inlet. The reservoir chamber receives the ventilation gas via the baffle. The inlet is maintains a constant gas pressure within the portion of the reservoir chamber that is being filled with the ventilation gas.

    Abstract translation: 呈现用于分配流体的盒。 墨盒包括用于接收流体并用于接收通气气体的储存室。 储存室包括用于接收通气气体的入口和用于分配流体的出口。 当处于操作位置时，储存室的至少一部分填充有通气气体。 入口位于填充有通气气体的部分中。 流体包含试剂。 墨盒还包括用于限制通过入口的气体扩散的挡板。 储存室通过挡板接收通气气体。 入口在储存室的被填充有通风气体的部分内保持恒定的气体压力。

    Rotatable cartridge for processing and analyzing a biological sample and dispensing method therewith
    5.
    发明授权
    Rotatable cartridge for processing and analyzing a biological sample and dispensing method therewith 有权

    公开(公告)号：US11406979B2

    公开(公告)日：2022-08-09

    申请号：US16599673

    申请日：2019-10-11

    Applicant: ROCHE DIAGNOSTICS OPERATIONS, INC.

    Inventor： Christoph Boehm ,  Sascha Lutz ,  Juergen Spinke

    IPC: B01L3/00 ,  G01N1/38 ,  G01N35/00 ,  G01N35/10

    Abstract: An automatic analyzer cartridge, spinnable about a rotational axis, has fluid and aliquoting chambers, a metering chamber connected to a vent that is nearer to the rotational axis than the metering chamber, first and second ducts connecting the fluid and aliquoting chambers, and the metering and aliquoting chambers, respectively. Metering chamber side walls taper away from a central region, wherein capillary action next to the walls is greater than in the central region. Fluid flows to the metering chamber using capillary action via the second duct that has an entrance and exit in the aliquoting and metering chambers, respectively; the exit being closer to the rotational axis than the entrance. A downstream fluidic element connects to the metering chamber via a valve. A fluidic structure receives and processes a biological sample into the processed biological sample and has a measurement structure that enables measurement of the processed biological sample.

    Rotatable cartridge for processing and analyzing a biological sample
    6.
    发明授权
    Rotatable cartridge for processing and analyzing a biological sample 有权

    公开(公告)号：US10478817B2

    公开(公告)日：2019-11-19

    申请号：US15943093

    申请日：2018-04-02

    Applicant: ROCHE DIAGNOSTICS OPERATIONS, INC.

    Inventor： Christoph Boehm ,  Sascha Lutz ,  Juergen Spinke

    IPC: B01L3/00 ,  G01N1/38 ,  G01N35/00 ,  G01N35/10

    Abstract: An automatic analyzer cartridge, spinnable about a rotational axis, has fluid and aliquoting chambers, a metering chamber connected to a vent that is nearer to the rotational axis than the metering chamber, first and second ducts connecting the fluid and aliquoting chambers, and the metering and aliquoting chambers, respectively. Metering chamber side walls taper away from a central region, wherein capillary action next to the walls is greater than in the central region. Fluid flows to the metering chamber using capillary action via the second duct that has an entrance and exit in the aliquoting and metering chambers, respectively; the exit being closer to the rotational axis than the entrance. A downstream fluidic element connects to the metering chamber via a valve. A fluidic structure receives and processes a biological sample into the processed biological sample and has a measurement structure that enables measurement of the processed biological sample.

    Cartridge with a rotatable lid
    7.
    发明授权
    Cartridge with a rotatable lid 有权

    公开(公告)号：US10086373B2

    公开(公告)日：2018-10-02

    申请号：US15352698

    申请日：2016-11-16

    Applicant: Roche Diagnostics Operations, Inc.

    Inventor： Christoph Boehm ,  Sascha Lutz ,  Juergen Spinke ,  Thorsten Brueckner

    IPC: B01L3/00 ,  G01N35/00 ,  G01N21/07 ,  G01N21/64 ,  G01N21/03

    Abstract: An automatic analyzer cartridge, spinnable around a rotational axis, has a support structure with a front face perpendicular to the rotational axis, a fluidic structure for processing a biological sample into the processed biological sample, a measurement structure with at least one detection zone on the front face, and a rotatable lid covering the front face. The rotatable lid is rotatable about the rotational axis relative to the support structure from a first position relative to the support structure to a second position relative to the support structure. The rotatable lid has a sample inlet opening and a detection zone opening. In the first position, a sample inlet is aligned with the sample inlet opening and the measurement structure is covered by the rotatable lid. In the second position, the sample inlet is covered by the rotatable lid and the measurement structure is aligned with the detection zone opening.

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