摘要:
Devices, systems, and methods provide for intravascular or extravascular delivery of renal denervation therapy and/or renal control stimulation therapy. Wireless vascular thermal transfer apparatuses and methods provide for one or both of production of current densities sufficient to ablate renal nerves and terminate renal sympathetic nerve activity, and production of current densities sufficient to induce endothelium dependent vasodilation of the renal artery bed. A common apparatus may be used for both renal ablation and control of renal function locally after renal denervation.
摘要:
Devices, systems, and methods provide for intravascular or extravascular delivery of renal denervation therapy and/or renal control stimulation therapy. Wireless vascular thermal transfer apparatuses and methods provide for one or both of production of current densities sufficient to ablate renal nerves and terminate renal sympathetic nerve activity, and production of current densities sufficient to induce endothelium dependent vasodilation of the renal artery bed. A common apparatus may be used for both renal ablation and control of renal function locally after renal denervation.
摘要:
Devices, systems, and methods facilitate modification of renal sympathetic nerve activity using a force generating arrangement. A device for mechanically modifying renal sympathetic nerve activity includes a contact arrangement having a shape that generally conforms to a portion of a renal artery wall and is configured for placement at the renal artery wall portion. A compression arrangement is configured to cooperate with the contact arrangement to place the wall portion of the renal artery in compression sufficient to achieve a desired reduction in renal sympathetic nerve activity. The compression arrangement and the contact arrangement are preferably configured to cooperatively place the wall portion of the renal artery in compression sufficient to irreversibly terminate renal sympathetic nerve activity.
摘要:
A renal denervation apparatus includes a treatment element dimensioned for deployment on or within a renal artery of a patient. The treatment element comprises a predefined pattern arranged to complete at least one revolution of the treatment element. The apparatus includes a treatment source. The treatment source and treatment element are configured to cooperatively facilitate communication of an agent from the treatment source to the pattern arrangement of the treatment element. The treatment element is configured to deliver denervation therapy using the agent via the pattern arrangement to one or more regions of the renal artery adjacent the pattern arrangement, such that at least one complete revolution of the renal artery is subjected to the denervation therapy.
摘要:
A medical device delivery system, having a rolling retractable sheath covering a medical device mounting region on the system is disclosed. The rolling retractable sheath comprises an inner wall and an outer wall and may be formed of one or more materials, optionally porous. Optionally, a lubricant may be applied selectively to the interior and exterior walls of the stent.
摘要:
A guidewire having a proximal section, a distal section, and a transition section is disclosed. In one exemplary embodiment of the present invention, the proximal section may be formed of a relatively stiff, inelastic material, whereas the distal section may be formed of a relatively flexible, elastic material having super-elastic properties. A coupling member may be placed adjacent to the transition section to secure the proximal and distal sections together.
摘要:
A sheath for delivering and/or retrieving an embolic protection filtering devices. The sheath may include a proximal portion and a distal portion. The distal portion may be expandable and may include a bulbous member or region. Additionally, the sheath may include structural support in a number of different forms.
摘要:
A percutaneous medical device that may include a stopper having a first end, a second end and a lumen therebetween, the stopper having first state where the lumen has a first cross-sectional area and a second state where the lumen has a second cross-sectional area less than the first cross-sectional area, the stopper having a slit between the first end and the second end when in the first state, the slit defining a gap, the stopper when in the second state having no bias to move to the first state at body temperature, the stopper having a distance of less than 3 cm between the first end and the second end and apparatus and methods of use pertaining thereto.
摘要:
Guidewire with an improved distal end. A guidewire with an improved distal end may include a core wire, a solder tip disposed at a distal end of the core wire, a radiopaque inner coil coupled to the distal end of the core wire, an outer coil disposed along the length of the core wire, and a distal hub coupled to the core wire and disposed proximate a distal end of the inner coil.