公开(公告)号：US5074881A

公开(公告)日：1991-12-24

申请号：US494453

申请日：1990-03-16

申请人： Roger Thull ,  Guenther Zeiler

发明人： Roger Thull ,  Guenther Zeiler

IPC分类号： A61F2/00 ,  A61F2/30 ,  A61F2/32 ,  A61F2/34

CPC分类号： A61F2/34 ,  A61F2/30767 ,  A61F2/3094 ,  A61F2002/30324 ,  A61F2002/30579 ,  A61F2002/30616 ,  A61F2002/30787 ,  A61F2002/30822 ,  A61F2002/30906 ,  A61F2002/3098 ,  A61F2002/3266 ,  A61F2002/3291 ,  A61F2002/3401 ,  A61F2002/3403 ,  A61F2002/3409 ,  A61F2002/3411 ,  A61F2002/343 ,  A61F2002/344 ,  A61F2002/347 ,  A61F2002/3475 ,  A61F2002/3482 ,  A61F2250/0036 ,  A61F2310/00023 ,  A61F2310/00407 ,  A61F2310/00598 ,  A61F2310/00616 ,  A61F2310/00634 ,  A61F2310/0064 ,  A61F2310/00658 ,  A61F2310/00856

摘要： A hip joint socket for implantation without cement into the acetabulum of the hip bone, consisting of an elastic socket support, which has the shape of an essentiallly hemispherical shell and can be inserted in an interlocking manner into the correspondingly prepared acetabulum bed. The socket support is formed so that after its implantation it quicklly grows together with the hip bone, and, even with considerable stress, relative movement between the socket support and the acetabulum is prevented. This is attained by constructing the socket support so that it exhibits its greatest stiffness in cranial portion in the implanted state, while in the downward (caudal) direction the elasticity of socket support increases. The wall thickness of socket support is greatest in cranial portion and decreases in the direction toward caudal portion. In the elastic caudal portion of the socket support, two or more notches are provided that run parallel or substantially parallel to the equatorial plane with increased elasticity at different distances from the equatorial plane.

摘要翻译： 一种用于将无水泥植入髋骨的髋臼的髋关节插座，其由弹性插座支撑件组成，其具有基本上半球形外壳的形状，并且可以互锁方式插入到相应制备的髋臼床中。 插座支撑件形成为使得其在植入之后与髋骨一起快速生长，并且即使在相当大的应力下，也可以防止插座支撑件和髋臼之间的相对移动。 这通过构造插座支撑件来实现，使得其在植入状态下在颅部显示出最大的刚度，而在向下（尾端）方向上插座支撑件的弹性增加。 插座支架的壁厚在头部最大，并且朝向尾部方向减小。 在插座支撑件的弹性尾部，提供两个或更多个凹槽，其平行或基本上平行于赤道平面，在与赤道平面不同的距离处具有增加的弹性。

公开(公告)号：US20120083898A1

公开(公告)日：2012-04-05

申请号：US13253597

申请日：2011-10-05

申请人： Roger Thull ,  Ulrike Thull

发明人： Roger Thull ,  Ulrike Thull

IPC分类号： A61F2/28

摘要： In a prosthesis component of a joint endoprosthesis, the prosthesis component comprises a sliding surface that is designed to form a sliding joint with a counter sliding surface of another prosthesis component. The sliding surface may be formed by a sliding surface coating deposited on the body of the prosthesis component, wherein the sliding surface coating has an antimicrobial effect. The sliding surface coating is active against microorganisms in the area of the sliding joint.

摘要翻译： 在关节内假体的假体部件中，假体部件包括被设计成与另一个假体部件的反向滑动表面形成滑动关节的滑动表面。 滑动表面可以通过沉积在假体部件的主体上的滑动表面涂层形成，其中滑动表面涂层具有抗微生物效果。 滑动表面涂层在滑动关节区域对微生物有活性。

公开(公告)号：US20110272276A1

公开(公告)日：2011-11-10

申请号：US13088844

申请日：2011-04-18

申请人： Roger Thull ,  Ulrike Thull

发明人： Roger Thull ,  Ulrike Thull

IPC分类号： A61L27/54 ,  A61K9/00 ,  A61F2/02 ,  C25B9/06

CPC分类号： A61L27/54 ,  A61L31/16 ,  A61L2300/104 ,  A61L2300/404

摘要： In a coated implant that releases silver ions in the human body and thereby has an antimicrobial effect, a first surface component of the coating is formed by an anode material. A second surface component of the coating is formed by a cathode material. The cathode material is higher in the electrochemical voltage sequence than the anode material. The cathode and the anode are connected with one another in an electrically conducting manner. Together with the body electrolyte in the vicinity of the implant the anode and the cathode material form a plurality of local galvanic elements.

摘要翻译： 在人体中释放银离子并由此具有抗菌作用的涂覆植入物中，涂层的第一表面组分由阳极材料形成。 涂层的第二表面组分由阴极材料形成。 阴极材料的电化学电压序列高于阳极材料。 阴极和阳极以导电方式彼此连接。 与植入物附近的身体电解质一起，阳极和阴极材料形成多个局部电流元件。

公开(公告)号：US08845751B2

公开(公告)日：2014-09-30

申请号：US12235356

申请日：2008-09-22

申请人： Helmut D. Link ,  Roger Thull

发明人： Helmut D. Link ,  Roger Thull

IPC分类号： A61F2/28 ,  A61L33/00 ,  B05D3/00 ,  A61F2/36 ,  A61F2/30 ,  A61F2/38

CPC分类号： A61F2/30767 ,  A61F2/28 ,  A61F2/3094 ,  A61F2/3607 ,  A61F2/38 ,  A61F2002/2825 ,  A61F2002/30405 ,  A61F2002/30677 ,  A61F2002/3092 ,  A61F2002/30929 ,  A61F2220/0025 ,  A61F2310/00407 ,  A61F2310/00443 ,  A61F2310/00449 ,  A61F2310/00467 ,  A61F2310/00485 ,  A61F2310/00491 ,  A61F2310/0052 ,  A61F2310/00538 ,  A61F2310/00544 ,  A61F2310/0055 ,  A61F2310/00568 ,  A61F2310/00856

摘要： An endoprosthesis component and a method for producing an endoprosthesis component is disclosed. The endoprosthesis component comprises a body predefining the shape of the endoprosthesis component. On surface portions with which the endoprosthesis component in the implanted state is in contact with human tissue, the body is covered with an outer layer which comprises a nitride, an oxynitride or an oxide based on a refractory metal and which contains silver and/or copper. An intermediate layer is arranged between the outer layer and the body in such a way that parts of the intermediate layer are accessible from the outside. The endoprosthesis component enables generation of a long-term antimicrobial action with the outer layer and, in addition, action on the surrounding tissue from the intermediate layer.

摘要翻译： 公开了内用假体成分和内用假体成分的制造方法。 内假体部件包括预先定义内假体部件的形状的主体。 在植入状态的内用假体成分与人体组织接触的表面部分上，主体被包含氮化物，氮氧化物或基于难熔金属的氧化物并且含有银和/或铜的外层覆盖 。 中间层被布置在外层和主体之间，使得中间层的一部分可从外部接近。 内用假体组分能够产生与外层的长期抗微生物作用，并且还可以对来自中间层的周围组织起作用。

公开(公告)号：US07473312B2

公开(公告)日：2009-01-06

申请号：US10557833

申请日：2004-05-19

申请人： Jake Barralet ,  Uwe Gbureck ,  Roger Thull

发明人： Jake Barralet ,  Uwe Gbureck ,  Roger Thull

IPC分类号： C04B12/02

CPC分类号： A61L24/0063 ,  A61L27/425 ,  A61L2430/02

摘要： In a first aspect, the present invention discloses a self setting calcium phosphate cement comprising:—(i) a powdered component, said powdered component having an average particle size d50 of less than 15 μm, and (ii) a calcium phosphate based powder, said powder having an average particle size d50 greater than that of the powdered component, said powdered component and said calcium phosphate based powder being suspended in water containing a dissolved zeta potential increasing additive in sufficient quantity to increase the zeta potential of the suspended particles to at least 30 mV, and wherein the zeta potential increasing additive is chosen to be compatible with the setting pH of the same calcium phosphate cement without the zeta potential increasing additive. In a second aspect, the invention discloses a shelf-stable acidic setting cement powder comprising:—(i) a calcium phosphate based powder, and (ii) a powdered compound which, upon addition of water to form a cement paste, retards the cement setting reaction or increases the zeta potential of the resultant suspended particles to at least −30 mV.

摘要翻译： 在第一方面，本发明公开了一种自定型磷酸钙水泥，其包括：（i）粉末状成分，所述粉末成分的平均粒径d50小于15μm，和（ii）磷酸钙基粉末， 所述粉末的平均粒度d50大于粉末成分的平均粒径，所述粉末成分和所述磷酸钙粉末以足够的量悬浮在含有溶解的ζ电位增加添加剂的水中，以将悬浮颗粒的ζ电位增加到 至少30mV，并且其中选择ζ电位增加添加剂与不含ζ电位增加添加剂的相同磷酸钙水泥的凝固pH相容。 在第二方面，本发明公开了一种搁置稳定的酸性凝固水泥粉末，其包括：（i）磷酸钙基粉末，和（ii）粉末状化合物，其在添加水以形成水泥浆料时延迟所述水泥 凝固反应或将所得悬浮颗粒的ζ电位提高至至少-30mV。

公开(公告)号：US20060213398A1

公开(公告)日：2006-09-28

申请号：US10557833

申请日：2004-05-19

申请人： Jake Barralet ,  Uwe Gbureck ,  Roger Thull

发明人： Jake Barralet ,  Uwe Gbureck ,  Roger Thull

IPC分类号： C04B28/34

CPC分类号： A61L24/0063 ,  A61L27/425 ,  A61L2430/02

摘要： In a first aspect, the present invention discloses a self setting calcium phosphate cement comprising:—(i) a powdered component, said powdered component having an average particle size d50 of less than 15 μm, and (ii) a calcium phosphate based powder, said powder having an average particle size d50 greater than that of the powdered component, said powdered component and said calcium phosphate based powder being suspended in water containing a dissolved zeta potential increasing additive in sufficient quantity to increase the zeta potential of the suspended particles to at least 30 mV, and wherein the zeta potential increasing additive is chosen to be compatible with the setting pH of the same calcium phosphate cement without the zeta potential increasing additive. In a second aspect, the invention discloses a shelf-stable acidic setting cement powder comprising:—(i) a calcium phosphate based powder, and (ii) a powdered compound which, upon addition of water to form a cement paste, retards the cement setting reaction or increases the zeta potential of the resultant suspended particles to at least −30 mV.

摘要翻译： 在第一方面，本发明公开了一种自设磷酸钙水泥，其包括：（i）粉末状成分，所述粉末成分的平均粒径d <50μm小于15μm，和（ ii）磷酸钙基粉末，所述粉末具有比粉末组分大的平均粒度d 50以下，所述粉末成分和所述磷酸钙基粉末悬浮在含有溶解的ζ电位的水中 增加足够量的添加剂以将悬浮颗粒的ζ电位增加至至少30mV，并且其中选择ζ电位增加添加剂与不具有ζ电位增加添加剂的相同磷酸钙水泥的凝固pH相容。 在第二方面，本发明公开了一种搁置稳定的酸性凝固水泥粉末，其包括：（i）磷酸钙基粉末，和（ii）粉末状化合物，其在添加水以形成水泥浆料时延迟所述水泥 凝固反应或将所得悬浮颗粒的ζ电位提高至至少-30mV。