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公开(公告)号：US20100198357A1
公开(公告)日：2010-08-05
申请号：US12759455
申请日：2010-04-13
Applicant: Thomas A. Fuller , Richard A. Wysk , Wayne J. Sebastianelli
Inventor： Thomas A. Fuller , Richard A. Wysk , Wayne J. Sebastianelli
CPC classification number: A61N1/30 , A61B17/60 , A61B17/86 , A61B17/864 , A61B17/866 , A61B17/8685 , A61B2017/00734 , A61F2/0077 , A61F2/0095 , A61F2/28 , A61F2/30 , A61F2/30724 , A61F2/30744 , A61F2/30767 , A61F2/32 , A61F2/34 , A61F2/36 , A61F2/3609 , A61F2/3662 , A61F2/367 , A61F2/3676 , A61F2002/009 , A61F2002/2821 , A61F2002/30235 , A61F2002/30322 , A61F2002/30329 , A61F2002/30354 , A61F2002/30405 , A61F2002/30438 , A61F2002/305 , A61F2002/30535 , A61F2002/30589 , A61F2002/30604 , A61F2002/30668 , A61F2002/30677 , A61F2002/30718 , A61F2002/30795 , A61F2002/30932 , A61F2002/3611 , A61F2002/3625 , A61F2002/3631 , A61F2002/368 , A61F2002/3692 , A61F2002/482 , A61F2220/0025 , A61F2220/0033 , A61F2220/0041 , A61F2230/0069 , A61F2250/0001 , A61F2250/0026 , A61F2250/0043 , A61F2250/0058 , A61F2310/00029 , A61F2310/00059 , A61F2310/00065 , A61F2310/00071 , A61F2310/00077 , A61F2310/00083 , A61F2310/00107 , A61F2310/00113 , A61F2310/00149 , A61F2310/00155 , A61F2310/00395 , A61F2310/00413 , A61F2310/00449 , A61F2310/00455 , A61F2310/00461 , A61F2310/00467 , A61F2310/00473 , A61F2310/00514 , A61F2310/0052 , A61F2310/00562 , A61F2310/00568 , A61L2/0082 , A61L27/30 , A61L27/306 , A61L27/54 , A61L2300/102 , A61L2300/104 , A61L2300/404 , A61L2300/602 , A61L2300/606 , A61L2430/02 , A61N1/00 , A61N1/18 , A61N1/20 , A61N1/205
Abstract: A medical implant system is described for inhibiting infection associated with a joint prosthesis implant. An inventive system includes an implant body made of a biocompatible material which has a metal component disposed on an external surface of the implant body. A current is allowed to flow to the metal component, stimulating release of metal ions toxic to microbes, such as bacteria, protozoa, fungi, and viruses. One detailed system is completely surgically implantable in the patient such that no part of the system is external to the patient while the system is in use. In addition, externally controlled devices are provided which allow for modulation of implanted components.
Abstract translation: 描述了用于抑制与关节假体植入物相关联的感染的医疗植入系统。 本发明的系统包括由生物相容性材料制成的植入体，其具有设置在植入物本体的外表面上的金属部件。 允许电流流向金属部件，刺激金属离子释放对细菌，原生动物，真菌和病毒等微生物有毒。 一个详细的系统完全可手术植入患者体内，使得在系统使用时，系统的任何部分都不在病人的外部。 此外，提供允许植入部件的调制的外部控制装置。
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公开(公告)号：US20080133026A1
公开(公告)日：2008-06-05
申请号：US11551298
申请日：2006-10-20
Applicant: Sio-Hou LEI , Kai-Lu WANG , Barry CHEN , Wenny KAO
Inventor： Sio-Hou LEI , Kai-Lu WANG , Barry CHEN , Wenny KAO
CPC classification number: A61F2/30965 , A61F2/30767 , A61F2/3094 , A61F2/32 , A61F2/34 , A61F2/36 , A61F2/3662 , A61F2002/30011 , A61F2002/30957 , A61F2002/3625 , A61F2002/3692 , A61F2250/0023 , A61F2310/00023 , A61F2310/00071 , A61F2310/00077 , A61F2310/00113 , A61F2310/00155 , A61F2310/00407 , A61F2310/00461 , A61F2310/00467 , A61F2310/0052 , A61F2310/00568 , B21D26/033 , C23C30/00 , C25D7/04
Abstract: An artificial bone includes a bone-shaped hollow metal body confining a sealed space and having two opposite closed ends, and a porous structure disposed in the sealed space. A method for making the artificial bone includes the steps of: positioning a metal tube in a bone-shaped mold cavity of a mold, hydro-forming the metal tube into a bone-shaped hollow tube in the bone-shaped mold cavity by injecting a high pressure fluid into the metal tube, disposing a crumple of metal wire into the bone-shaped hollow tube, depositing a metal coating on the metal wire and an inner surface of the bone-shaped hollow tube to form a porous structure in the bone-shaped hollow tube, and sealing the bone-shaped hollow tube.
Abstract translation: 人造骨包括限定密封空间并具有两个相对封闭端的骨形中空金属体，以及设置在密封空间中的多孔结构。 制造人造骨的方法包括以下步骤：将金属管定位在模具的骨形模腔中，通过注射成形金属管将其成型为骨形模腔中的骨形中空管 将高压流体插入金属管中，将金属丝的褶皱布置在骨形中空管中，在金属线上沉积金属涂层和骨形中空管的内表面，以在骨头中形成多孔结构， 形状的中空管，并密封骨形中空管。
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3.发明申请LASER BASED METAL DEPOSITION (LBMD) OF ANTIMICROBIALS TO IMPLANT SURFACES 失效基于激光的金属沉积（LBMD）抗微生物植入表面公开(公告)号：US20070287027A1
公开(公告)日：2007-12-13
申请号：US11624041
申请日：2007-01-17
Applicant: Daniel F. Justin , Brent E. Stucker , Durga Janaki Ram Gabbita , David William Britt
Inventor： Daniel F. Justin , Brent E. Stucker , Durga Janaki Ram Gabbita , David William Britt
CPC classification number: A61F2/30767 , A61C8/0012 , A61F2/3099 , A61F2/36 , A61F2/3662 , A61F2/38 , A61F2/3804 , A61F2/3859 , A61F2/40 , A61F2/4225 , A61F2/4241 , A61F2/4261 , A61F2002/30451 , A61F2002/30604 , A61F2002/30733 , A61F2002/30805 , A61F2002/30878 , A61F2002/30922 , A61F2002/30925 , A61F2002/30929 , A61F2002/30934 , A61F2002/30967 , A61F2002/3097 , A61F2002/30971 , A61F2002/3611 , A61F2002/3625 , A61F2002/3652 , A61F2002/4253 , A61F2220/0058 , A61F2310/00017 , A61F2310/00023 , A61F2310/00029 , A61F2310/00089 , A61F2310/00095 , A61F2310/00131 , A61F2310/00149 , A61F2310/00293 , A61F2310/00395 , A61F2310/00401 , A61F2310/00407 , A61F2310/00413 , A61F2310/00467 , A61F2310/00473 , A61F2310/00485 , A61F2310/00491 , A61F2310/00514 , A61F2310/0052 , A61F2310/00532 , A61F2310/00544 , A61F2310/00556 , A61F2310/00562 , A61F2310/00568 , A61L27/04 , A61L27/30 , A61L27/54 , A61L2300/102 , A61L2300/104 , A61L2300/404 , B23K26/144 , B23K26/147 , B23K26/32 , B23K26/34 , B23K2103/50 , C23C4/12 , C23C24/10 , C23C26/00 , C23C26/02 , Y10T428/12458 , Y10T428/12479 , Y10T428/12493 , Y10T428/12771 , Y10T428/12847
Abstract: A method is provided for depositing a hard wear resistant surface onto a porous or non-porous base material of a medical implant. The wear resistant surface of the medical implant device may be formed by a Laser Based Metal Deposition (LBMD) method such as Laser Engineered Net Shaping (LENS). The wear resistant surface may include a blend of multiple different biocompatible materials. Further, functionally graded layers of biocompatible materials may be used to form the wear resistant surface. Usage of a porous material for the base may promote bone ingrowth to allow the implant to fuse strongly with the bone of a host patient. The hard wear resistant surface provides device longevity, particularly when applied to bearing surfaces such as artificial joint bearing surfaces or a dental implant bearing surfaces. An antimicrobial material such as silver may be deposited in combination with a metal to form an antimicrobial surface deposit.
Abstract translation: 提供了一种将硬耐磨表面沉积到医用植入物的多孔或非多孔基材上的方法。 医疗植入装置的耐磨表面可以通过激光基金属沉积（LBMD）方法形成，例如激光工程网整形（LENS）。 耐磨表面可以包括多种不同生物相容性材料的混合物。 此外，生物相容性材料的功能梯度层可用于形成耐磨表面。 用于基底的多孔材料的使用可以促进骨向内生长以允许植入物与宿主患者的骨骼牢固地融合。 耐磨损的表面提供了设备寿命，特别是当应用于诸如人造关节轴承表面或牙科植入物轴承表面的支承表面时。 抗微生物材料如银可以与金属组合沉积以形成抗微生物表面沉积物。
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公开(公告)号：US08135466B2
公开(公告)日：2012-03-13
申请号：US11922979
申请日：2006-06-30
Applicant: Thomas A. Fuller , Richard A. Wysk , Wayne J. Sebastianelli
Inventor： Thomas A. Fuller , Richard A. Wysk , Wayne J. Sebastianelli
IPC: A61N1/00
CPC classification number: A61N1/30 , A61B17/60 , A61B17/86 , A61B17/864 , A61B17/866 , A61B17/8685 , A61B2017/00734 , A61F2/0077 , A61F2/0095 , A61F2/28 , A61F2/30 , A61F2/30724 , A61F2/30744 , A61F2/30767 , A61F2/32 , A61F2/34 , A61F2/36 , A61F2/3609 , A61F2/3662 , A61F2/367 , A61F2/3676 , A61F2002/009 , A61F2002/2821 , A61F2002/30235 , A61F2002/30322 , A61F2002/30329 , A61F2002/30354 , A61F2002/30405 , A61F2002/30438 , A61F2002/305 , A61F2002/30535 , A61F2002/30589 , A61F2002/30604 , A61F2002/30668 , A61F2002/30677 , A61F2002/30718 , A61F2002/30795 , A61F2002/30932 , A61F2002/3611 , A61F2002/3625 , A61F2002/3631 , A61F2002/368 , A61F2002/3692 , A61F2002/482 , A61F2220/0025 , A61F2220/0033 , A61F2220/0041 , A61F2230/0069 , A61F2250/0001 , A61F2250/0026 , A61F2250/0043 , A61F2250/0058 , A61F2310/00029 , A61F2310/00059 , A61F2310/00065 , A61F2310/00071 , A61F2310/00077 , A61F2310/00083 , A61F2310/00107 , A61F2310/00113 , A61F2310/00149 , A61F2310/00155 , A61F2310/00395 , A61F2310/00413 , A61F2310/00449 , A61F2310/00455 , A61F2310/00461 , A61F2310/00467 , A61F2310/00473 , A61F2310/00514 , A61F2310/0052 , A61F2310/00562 , A61F2310/00568 , A61L2/0082 , A61L27/30 , A61L27/306 , A61L27/54 , A61L2300/102 , A61L2300/104 , A61L2300/404 , A61L2300/602 , A61L2300/606 , A61L2430/02 , A61N1/00 , A61N1/18 , A61N1/20 , A61N1/205
Abstract: A medical implant system is described for inhibiting infection associated with a joint prosthesis implant. An inventive system includes an implant body made of a biocompatible material which has a metal component disposed on an external surface of the implant body. A current is allowed to flow to the metal component, stimulating release of metal ions toxic to microbes, such as bacteria, protozoa, fungi, and viruses. One detailed system is completely surgically implantable in the patient such that no part of the system is external to the patient while the system is in use. In addition, externally controlled devices are provided which allow for modulation of implanted components.
Abstract translation: 描述了用于抑制与关节假体植入物相关联的感染的医疗植入系统。 本发明的系统包括由生物相容性材料制成的植入体，其具有设置在植入物本体的外表面上的金属部件。 允许电流流向金属部件，刺激金属离子释放对细菌，原生动物，真菌和病毒等微生物有毒。 一个详细的系统完全可手术植入患者体内，使得在系统使用时，系统的任何部分都不在病人的外部。 此外，提供允许植入部件的调制的外部控制装置。
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公开(公告)号：US08118028B2
公开(公告)日：2012-02-21
申请号：US12311152
申请日：2007-09-20
Applicant: Melinda-Kinga Karpati
Inventor： Melinda-Kinga Karpati
CPC classification number: A61F6/14 , A61F2310/00065 , A61F2310/00077 , A61F2310/00083 , A61F2310/00113 , A61F2310/00155 , A61F2310/00455 , A61F2310/00467 , A61F2310/00473 , A61F2310/0052 , A61F2310/00568
Abstract: An intrauterine contraceptive device comprising a carrier body (1) and an active metallic alloy (4), characterized in that the active metallic alloy is of the formula ZnxCuyMnzAuk (I) or ZnxCuyMnzAgk (II), wherein x+y+z+k=100 weight %, x is in the range from approximately 18 to 30 weight %, z is in the range from approximately 0.5 to 3 weight %, and k is in the range from approximately 3 to 12 weight %, y being the balance.
Abstract translation: 1.一种子宫内避孕装置，其特征在于，所述活性金属合金具有式Zn x Cu y Mn z A k（I）或Zn x Cu y Mn z A g k（II），其中x + y + z + k = 100重量％，x在约18至30重量％的范围内，z在约0.5至3重量％的范围内，k在约3至12重量％的范围内，y为余量。
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Patent Agency Ranking
6.发明申请Laser Based Metal Deposition LBMD of Antimicrobials to Implant Surfaces 审中-公开基于激光的金属沉积LBMD对植入物表面的抗菌素公开(公告)号：US20110208304A1
公开(公告)日：2011-08-25
申请号：US13091810
申请日：2011-04-21
Applicant: Daniel F. Justin , Brent E. Stucker , Durga Janaki Ram Gabbita , David William Britt
Inventor： Daniel F. Justin , Brent E. Stucker , Durga Janaki Ram Gabbita , David William Britt
CPC classification number: A61F2/30767 , A61C8/0012 , A61F2/3099 , A61F2/36 , A61F2/3662 , A61F2/38 , A61F2/3804 , A61F2/3859 , A61F2/40 , A61F2/4225 , A61F2/4241 , A61F2/4261 , A61F2002/30451 , A61F2002/30604 , A61F2002/30733 , A61F2002/30805 , A61F2002/30878 , A61F2002/30922 , A61F2002/30925 , A61F2002/30929 , A61F2002/30934 , A61F2002/30967 , A61F2002/3097 , A61F2002/30971 , A61F2002/3611 , A61F2002/3625 , A61F2002/3652 , A61F2002/4253 , A61F2220/0058 , A61F2310/00017 , A61F2310/00023 , A61F2310/00029 , A61F2310/00089 , A61F2310/00095 , A61F2310/00131 , A61F2310/00149 , A61F2310/00293 , A61F2310/00395 , A61F2310/00401 , A61F2310/00407 , A61F2310/00413 , A61F2310/00467 , A61F2310/00473 , A61F2310/00485 , A61F2310/00491 , A61F2310/00514 , A61F2310/0052 , A61F2310/00532 , A61F2310/00544 , A61F2310/00556 , A61F2310/00562 , A61F2310/00568 , A61L27/04 , A61L27/30 , A61L27/54 , A61L2300/102 , A61L2300/104 , A61L2300/404 , B23K26/144 , B23K26/147 , B23K26/32 , B23K26/34 , B23K2103/50 , C23C4/12 , C23C24/10 , C23C26/00 , C23C26/02 , Y10T428/12458 , Y10T428/12479 , Y10T428/12493 , Y10T428/12771 , Y10T428/12847
Abstract: A method is provided for depositing a hard wear resistant surface onto a porous or non-porous base material of a medical implant. The wear resistant surface of the medical implant device may be formed by a Laser Based Metal Deposition (LBMD) method such as Laser Engineered Net Shaping (LENS). The wear resistant surface may include a blend of multiple different biocompatible materials. Further, functionally graded layers of biocompatible materials may be used to form the wear resistant surface. Usage of a porous material for the base may promote bone ingrowth to allow the implant to fuse strongly with the bone of a host patient. The hard wear resistant surface provides device longevity, particularly when applied to bearing surfaces such as artificial joint bearing surfaces or a dental implant bearing surfaces. An antimicrobial material such as silver may be deposited in combination with a metal to form an antimicrobial surface deposit.
Abstract translation: 提供了一种将硬耐磨表面沉积到医用植入物的多孔或非多孔基材上的方法。 医疗植入装置的耐磨表面可以通过激光基金属沉积（LBMD）方法形成，例如激光工程网整形（LENS）。 耐磨表面可以包括多种不同生物相容性材料的混合物。 此外，生物相容性材料的功能梯度层可用于形成耐磨表面。 用于基底的多孔材料的使用可以促进骨向内生长以允许植入物与宿主患者的骨骼牢固地融合。 耐磨损的表面提供了设备寿命，特别是当应用于诸如人造关节轴承表面或牙科植入物轴承表面的支承表面时。 抗微生物材料如银可以与金属组合沉积以形成抗微生物表面沉积物。
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公开(公告)号：US20100100188A1
公开(公告)日：2010-04-22
申请号：US11922979
申请日：2006-06-30
Applicant: Thomas A. Fuller , Richard A. Wysk , Wayne J. Sebastianelli
Inventor： Thomas A. Fuller , Richard A. Wysk , Wayne J. Sebastianelli
CPC classification number: A61N1/30 , A61B17/60 , A61B17/86 , A61B17/864 , A61B17/866 , A61B17/8685 , A61B2017/00734 , A61F2/0077 , A61F2/0095 , A61F2/28 , A61F2/30 , A61F2/30724 , A61F2/30744 , A61F2/30767 , A61F2/32 , A61F2/34 , A61F2/36 , A61F2/3609 , A61F2/3662 , A61F2/367 , A61F2/3676 , A61F2002/009 , A61F2002/2821 , A61F2002/30235 , A61F2002/30322 , A61F2002/30329 , A61F2002/30354 , A61F2002/30405 , A61F2002/30438 , A61F2002/305 , A61F2002/30535 , A61F2002/30589 , A61F2002/30604 , A61F2002/30668 , A61F2002/30677 , A61F2002/30718 , A61F2002/30795 , A61F2002/30932 , A61F2002/3611 , A61F2002/3625 , A61F2002/3631 , A61F2002/368 , A61F2002/3692 , A61F2002/482 , A61F2220/0025 , A61F2220/0033 , A61F2220/0041 , A61F2230/0069 , A61F2250/0001 , A61F2250/0026 , A61F2250/0043 , A61F2250/0058 , A61F2310/00029 , A61F2310/00059 , A61F2310/00065 , A61F2310/00071 , A61F2310/00077 , A61F2310/00083 , A61F2310/00107 , A61F2310/00113 , A61F2310/00149 , A61F2310/00155 , A61F2310/00395 , A61F2310/00413 , A61F2310/00449 , A61F2310/00455 , A61F2310/00461 , A61F2310/00467 , A61F2310/00473 , A61F2310/00514 , A61F2310/0052 , A61F2310/00562 , A61F2310/00568 , A61L2/0082 , A61L27/30 , A61L27/306 , A61L27/54 , A61L2300/102 , A61L2300/104 , A61L2300/404 , A61L2300/602 , A61L2300/606 , A61L2430/02 , A61N1/00 , A61N1/18 , A61N1/20 , A61N1/205
Abstract: A medical implant system is described for inhibiting infection associated with a joint prosthesis implant. An inventive system includes an implant body made of a biocompatible material which has a metal component disposed on an external surface of the implant body. A current is allowed to flow to the metal component, stimulating release of metal ions toxic to microbes, such as bacteria, protozoa, fungi, and viruses. One detailed system is completely surgically implantable in the patient such that no part of the system is external to the patient while the system is in use. In addition, externally controlled devices are provided which allow for modulation of implanted components.
Abstract translation: 描述了用于抑制与关节假体植入物相关联的感染的医疗植入系统。 本发明的系统包括由生物相容性材料制成的植入体，其具有设置在植入物本体的外表面上的金属部件。 允许电流流向金属部件，刺激金属离子释放对细菌，原生动物，真菌和病毒等微生物有毒。 一个详细的系统完全可手术植入患者体内，使得在系统使用时，系统的任何部分都不在病人的外部。 此外，提供允许植入部件的调制的外部控制装置。
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公开(公告)号：US20150182645A1
公开(公告)日：2015-07-02
申请号：US14644497
申请日：2015-03-11
Applicant: ArgentumCidalElectrics, Inc.
Inventor： Thomas A. FULLER , Richard A. WYSK , Wayne J. SEBASTIANELLI
CPC classification number: A61N1/30 , A61B17/60 , A61B17/86 , A61B17/864 , A61B17/866 , A61B17/8685 , A61B2017/00734 , A61F2/0077 , A61F2/0095 , A61F2/28 , A61F2/30 , A61F2/30724 , A61F2/30744 , A61F2/30767 , A61F2/32 , A61F2/34 , A61F2/36 , A61F2/3609 , A61F2/3662 , A61F2/367 , A61F2/3676 , A61F2002/009 , A61F2002/2821 , A61F2002/30235 , A61F2002/30322 , A61F2002/30329 , A61F2002/30354 , A61F2002/30405 , A61F2002/30438 , A61F2002/305 , A61F2002/30535 , A61F2002/30589 , A61F2002/30604 , A61F2002/30668 , A61F2002/30677 , A61F2002/30718 , A61F2002/30795 , A61F2002/30932 , A61F2002/3611 , A61F2002/3625 , A61F2002/3631 , A61F2002/368 , A61F2002/3692 , A61F2002/482 , A61F2220/0025 , A61F2220/0033 , A61F2220/0041 , A61F2230/0069 , A61F2250/0001 , A61F2250/0026 , A61F2250/0043 , A61F2250/0058 , A61F2310/00029 , A61F2310/00059 , A61F2310/00065 , A61F2310/00071 , A61F2310/00077 , A61F2310/00083 , A61F2310/00107 , A61F2310/00113 , A61F2310/00149 , A61F2310/00155 , A61F2310/00395 , A61F2310/00413 , A61F2310/00449 , A61F2310/00455 , A61F2310/00461 , A61F2310/00467 , A61F2310/00473 , A61F2310/00514 , A61F2310/0052 , A61F2310/00562 , A61F2310/00568 , A61L2/0082 , A61L27/30 , A61L27/306 , A61L27/54 , A61L2300/102 , A61L2300/104 , A61L2300/404 , A61L2300/602 , A61L2300/606 , A61L2430/02 , A61N1/00 , A61N1/18 , A61N1/20 , A61N1/205
Abstract: A medical implant system is described for inhibiting infection associated with a joint prosthesis implant. An inventive system includes an implant body made of a biocompatible material which has a metal component disposed on an external surface of the implant body. A current is allowed to flow to the metal component, stimulating release of metal ions toxic to microbes, such as bacteria, protozoa, fungi, and viruses. One detailed system is completely surgically implantable in the patient such that no part of the system is external to the patient while the system is in use. In addition, externally controlled devices are provided which allow for modulation of implanted components.
Abstract translation: 描述了用于抑制与关节假体植入物相关联的感染的医疗植入系统。 本发明的系统包括由生物相容性材料制成的植入体，其具有设置在植入物本体的外表面上的金属部件。 允许电流流向金属部件，刺激金属离子释放对细菌，原生动物，真菌和病毒等微生物有毒。 一个详细的系统完全可手术植入患者体内，使得在系统使用时，系统的任何部分都不在病人的外部。 此外，提供允许植入部件的调制的外部控制装置。
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公开(公告)号：US08845751B2
公开(公告)日：2014-09-30
申请号：US12235356
申请日：2008-09-22
Applicant: Helmut D. Link , Roger Thull
Inventor： Helmut D. Link , Roger Thull
CPC classification number: A61F2/30767 , A61F2/28 , A61F2/3094 , A61F2/3607 , A61F2/38 , A61F2002/2825 , A61F2002/30405 , A61F2002/30677 , A61F2002/3092 , A61F2002/30929 , A61F2220/0025 , A61F2310/00407 , A61F2310/00443 , A61F2310/00449 , A61F2310/00467 , A61F2310/00485 , A61F2310/00491 , A61F2310/0052 , A61F2310/00538 , A61F2310/00544 , A61F2310/0055 , A61F2310/00568 , A61F2310/00856
Abstract: An endoprosthesis component and a method for producing an endoprosthesis component is disclosed. The endoprosthesis component comprises a body predefining the shape of the endoprosthesis component. On surface portions with which the endoprosthesis component in the implanted state is in contact with human tissue, the body is covered with an outer layer which comprises a nitride, an oxynitride or an oxide based on a refractory metal and which contains silver and/or copper. An intermediate layer is arranged between the outer layer and the body in such a way that parts of the intermediate layer are accessible from the outside. The endoprosthesis component enables generation of a long-term antimicrobial action with the outer layer and, in addition, action on the surrounding tissue from the intermediate layer.
Abstract translation: 公开了内用假体成分和内用假体成分的制造方法。 内假体部件包括预先定义内假体部件的形状的主体。 在植入状态的内用假体成分与人体组织接触的表面部分上，主体被包含氮化物，氮氧化物或基于难熔金属的氧化物并且含有银和/或铜的外层覆盖 。 中间层被布置在外层和主体之间，使得中间层的一部分可从外部接近。 内用假体组分能够产生与外层的长期抗微生物作用，并且还可以对来自中间层的周围组织起作用。
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公开(公告)号：US08620431B2
公开(公告)日：2013-12-31
申请号：US13417269
申请日：2012-03-11
Applicant: Thomas A. Fuller , Richard A. Wysk , Wayne J. Sebastianelli
Inventor： Thomas A. Fuller , Richard A. Wysk , Wayne J. Sebastianelli
IPC: A61N1/00
CPC classification number: A61N1/30 , A61B17/60 , A61B17/86 , A61B17/864 , A61B17/866 , A61B17/8685 , A61B2017/00734 , A61F2/0077 , A61F2/0095 , A61F2/28 , A61F2/30 , A61F2/30724 , A61F2/30744 , A61F2/30767 , A61F2/32 , A61F2/34 , A61F2/36 , A61F2/3609 , A61F2/3662 , A61F2/367 , A61F2/3676 , A61F2002/009 , A61F2002/2821 , A61F2002/30235 , A61F2002/30322 , A61F2002/30329 , A61F2002/30354 , A61F2002/30405 , A61F2002/30438 , A61F2002/305 , A61F2002/30535 , A61F2002/30589 , A61F2002/30604 , A61F2002/30668 , A61F2002/30677 , A61F2002/30718 , A61F2002/30795 , A61F2002/30932 , A61F2002/3611 , A61F2002/3625 , A61F2002/3631 , A61F2002/368 , A61F2002/3692 , A61F2002/482 , A61F2220/0025 , A61F2220/0033 , A61F2220/0041 , A61F2230/0069 , A61F2250/0001 , A61F2250/0026 , A61F2250/0043 , A61F2250/0058 , A61F2310/00029 , A61F2310/00059 , A61F2310/00065 , A61F2310/00071 , A61F2310/00077 , A61F2310/00083 , A61F2310/00107 , A61F2310/00113 , A61F2310/00149 , A61F2310/00155 , A61F2310/00395 , A61F2310/00413 , A61F2310/00449 , A61F2310/00455 , A61F2310/00461 , A61F2310/00467 , A61F2310/00473 , A61F2310/00514 , A61F2310/0052 , A61F2310/00562 , A61F2310/00568 , A61L2/0082 , A61L27/30 , A61L27/306 , A61L27/54 , A61L2300/102 , A61L2300/104 , A61L2300/404 , A61L2300/602 , A61L2300/606 , A61L2430/02 , A61N1/00 , A61N1/18 , A61N1/20 , A61N1/205
Abstract: A medical implant system is described for inhibiting infection associated with a joint prosthesis implant. An inventive system includes an implant body made of a biocompatible material which has a metal component disposed on an external surface of the implant body. A current is allowed to flow to the metal component, stimulating release of metal ions toxic to microbes, such as bacteria, protozoa, fungi, and viruses. One detailed system is completely surgically implantable in the patient such that no part of the system is external to the patient while the system is in use. In addition, externally controlled devices are provided which allow for modulation of implanted components.
Abstract translation: 描述了用于抑制与关节假体植入物相关联的感染的医疗植入系统。 本发明的系统包括由生物相容性材料制成的植入体，其具有设置在植入物本体的外表面上的金属部件。 允许电流流向金属部件，刺激金属离子释放对细菌，原生动物，真菌和病毒等微生物有毒。 一个详细的系统完全可手术植入患者体内，使得在系统使用时，系统的任何部分都不在病人的外部。 此外，提供允许植入部件的调制的外部控制装置。
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