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公开(公告)号：US08845751B2
公开(公告)日：2014-09-30
申请号：US12235356
申请日：2008-09-22
Applicant: Helmut D. Link , Roger Thull
Inventor： Helmut D. Link , Roger Thull
CPC classification number: A61F2/30767 , A61F2/28 , A61F2/3094 , A61F2/3607 , A61F2/38 , A61F2002/2825 , A61F2002/30405 , A61F2002/30677 , A61F2002/3092 , A61F2002/30929 , A61F2220/0025 , A61F2310/00407 , A61F2310/00443 , A61F2310/00449 , A61F2310/00467 , A61F2310/00485 , A61F2310/00491 , A61F2310/0052 , A61F2310/00538 , A61F2310/00544 , A61F2310/0055 , A61F2310/00568 , A61F2310/00856
Abstract: An endoprosthesis component and a method for producing an endoprosthesis component is disclosed. The endoprosthesis component comprises a body predefining the shape of the endoprosthesis component. On surface portions with which the endoprosthesis component in the implanted state is in contact with human tissue, the body is covered with an outer layer which comprises a nitride, an oxynitride or an oxide based on a refractory metal and which contains silver and/or copper. An intermediate layer is arranged between the outer layer and the body in such a way that parts of the intermediate layer are accessible from the outside. The endoprosthesis component enables generation of a long-term antimicrobial action with the outer layer and, in addition, action on the surrounding tissue from the intermediate layer.
Abstract translation: 公开了内用假体成分和内用假体成分的制造方法。 内假体部件包括预先定义内假体部件的形状的主体。 在植入状态的内用假体成分与人体组织接触的表面部分上，主体被包含氮化物，氮氧化物或基于难熔金属的氧化物并且含有银和/或铜的外层覆盖 。 中间层被布置在外层和主体之间，使得中间层的一部分可从外部接近。 内用假体组分能够产生与外层的长期抗微生物作用，并且还可以对来自中间层的周围组织起作用。
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公开(公告)号：US07090496B2
公开(公告)日：2006-08-15
申请号：US10432025
申请日：2001-11-19
Applicant: Pierre Descouts , Björn-Owe Aronsson , Michael Grätzel , Carine Viornery , Peter Péchy
Inventor： Pierre Descouts , Björn-Owe Aronsson , Michael Grätzel , Carine Viornery , Peter Péchy
IPC: A61C8/00
CPC classification number: A61F2/28 , A61C8/0012 , A61C2008/0046 , A61F2/0095 , A61F2/30767 , A61F2310/00017 , A61F2310/00023 , A61F2310/00029 , A61F2310/00047 , A61F2310/00053 , A61F2310/00059 , A61F2310/00089 , A61F2310/00095 , A61F2310/00131 , A61F2310/00401 , A61F2310/00407 , A61F2310/00413 , A61F2310/00431 , A61F2310/00443 , A61F2310/00449 , A61F2310/00485 , A61F2310/00491 , A61F2310/00544 , A61F2310/00598 , A61F2310/00616 , A61F2310/0073 , A61F2310/00748 , A61F2310/00796 , A61F2310/00856 , A61F2310/0088 , A61F2310/00928 , A61F2310/00976 , A61L27/06 , A61L27/10 , A61L27/32 , A61L2430/02 , C07F9/3808 , C07F9/3843 , C07F9/3865 , C07F9/3873 , C07F9/4046 , C07F9/572 , C07F9/58 , C07F9/6506 , C07F9/6561
Abstract: Endosseous implant to be applied to human or animal bone, said implant having a surface made from a selected metal or a selected metal alloy or a ceramic, whereby said metal resp. metal alloy is selected from chromium, niobium, tantalum, vanadium, zirconium, aluminium, cobalt, nickel, stainless steels or an alloy thereof, said surface having a smooth or rough texture, characterized in that said surface has been treated with at least one pharmaceutically acceptable organic compound carrying at least one phosphonic acid group or a derivative thereof preferably a pharmaceutically acceptable salt or ester or amid thereof and method for producing said implant.
Abstract translation: 所述植入物具有由选定的金属或选定的金属合金或陶瓷制成的表面，其中所述金属， 金属合金选自铬，铌，钽，钒，锆，铝，钴，镍，不锈钢或其合金，所述表面具有光滑或粗糙的结构，其特征在于所述表面已经用至少一种药学上 携带至少一种膦酸基团的可接受的有机化合物或其衍生物优选其药学上可接受的盐或酯或其盐或其制备方法。
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公开(公告)号：US20040054422A1
公开(公告)日：2004-03-18
申请号：US10432026
申请日：2003-08-28
Inventor： Pierre Descouts , Bjorn-Owe Aronsson , Michael Gratzel , Carine Viornery , Peter Pechy
IPC: A61C008/00 , A61F002/28
CPC classification number: A61F2/28 , A61C8/0012 , A61C2008/0046 , A61F2/0095 , A61F2/30767 , A61F2310/00017 , A61F2310/00023 , A61F2310/00029 , A61F2310/00047 , A61F2310/00053 , A61F2310/00059 , A61F2310/00089 , A61F2310/00095 , A61F2310/00131 , A61F2310/00401 , A61F2310/00407 , A61F2310/00413 , A61F2310/00431 , A61F2310/00443 , A61F2310/00449 , A61F2310/00485 , A61F2310/00491 , A61F2310/00544 , A61F2310/00598 , A61F2310/00616 , A61F2310/0073 , A61F2310/00748 , A61F2310/00796 , A61F2310/00856 , A61F2310/0088 , A61F2310/00928 , A61F2310/00976 , A61L27/06 , A61L27/10 , A61L27/32 , A61L2430/02 , C07F9/3808 , C07F9/3843 , C07F9/3865 , C07F9/3873 , C07F9/4046 , C07F9/572 , C07F9/58 , C07F9/6506 , C07F9/6561
Abstract: Endosseous implant to be applied to a human or animal bone, wherein the surface of the implant is made from titanium or a titanium alloy, said implant having a smooth or rough surface texture, which is characterized in that said surface has been treated with at least one selected organic phosphonate compound or a pharmaceutically acceptable salt or ester or an amide thereof; process for producing said implants.
Abstract translation: 骨质植入物应用于人或动物骨，其中所述植入物的表面由钛或钛合金制成，所述植入物具有光滑或粗糙的表面纹理，其特征在于，所述表面至少已被处理 一种选择的有机膦酸酯化合物或其药学上可接受的盐或酯或其酰胺; 用于生产所述植入物的方法。
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公开(公告)号：US09549821B2
公开(公告)日：2017-01-24
申请号：US13884357
申请日：2011-11-09
Applicant: Toshio Matsumoto , Yuzo Daigo , Shinichi Ohmori , Komei Kato
Inventor： Toshio Matsumoto , Yuzo Daigo , Shinichi Ohmori , Komei Kato
CPC classification number: A61F2/4455 , A61F2/30771 , A61F2/44 , A61F2/442 , A61F2/4465 , A61F2002/30011 , A61F2002/30224 , A61F2002/30454 , A61F2002/30471 , A61F2002/30472 , A61F2002/30492 , A61F2002/30616 , A61F2002/30841 , A61F2002/30892 , A61F2002/3092 , A61F2002/30967 , A61F2002/3097 , A61F2002/30971 , A61F2002/4475 , A61F2002/448 , A61F2310/00023 , A61F2310/00431 , A61F2310/00443 , A61F2310/00485 , A61F2310/00491 , A61F2310/00497 , A61F2310/00514 , A61F2310/00532 , A61F2310/00544 , A61F2310/00562 , A61F2310/00976
Abstract: A vertebral body spacer of the present invention is used by being inserted between a vertebral body and a vertebral body (intervertebral space). The vertebral body spacer has a block body constituted of titanium or a titanium alloy as a main component thereof, and provided with a pair of contact surfaces to be made contact with the vertebral body and the vertebral body. The block body includes needle parts formed into a needle shape having both end portions and a porous part having through holes passing through the porous part in a thickness direction thereof, and a porosity of at least a surface of the porous part is larger than a porosity of each of the needle parts. The needle parts are inserted into the through holes so that the both end portions are projected from the contact surfaces.
Abstract translation: 通过插入椎体和椎体（椎间空间）来使用本发明的椎体间隔件。 椎体间隔物具有由钛或钛合金作为其主要成分构成的块体，并且具有与椎体和椎体接触的一对接触面。 块体包括形成为具有两端部的针状的针部和具有贯穿多孔部的厚度方向的贯通孔的多孔部，多孔部的至少表面的孔隙率大于孔隙率 的每个针部分。 针部分插入到通孔中，使得两个端部从接触表面突出。
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公开(公告)号：US20160206441A1
公开(公告)日：2016-07-21
申请号：US14982467
申请日：2015-12-29
Applicant: MITSUBISHI MATERIALS CORPORATION
Inventor： Toshio Matsumoto , Yuzo Daigo , Shinichi Ohmori , Komei Kato
CPC classification number: A61F2/4455 , A61F2/30771 , A61F2/44 , A61F2/442 , A61F2/4465 , A61F2002/30011 , A61F2002/30224 , A61F2002/30454 , A61F2002/30471 , A61F2002/30472 , A61F2002/30492 , A61F2002/30616 , A61F2002/30841 , A61F2002/30892 , A61F2002/3092 , A61F2002/30967 , A61F2002/3097 , A61F2002/30971 , A61F2002/4475 , A61F2002/448 , A61F2310/00023 , A61F2310/00431 , A61F2310/00443 , A61F2310/00485 , A61F2310/00491 , A61F2310/00497 , A61F2310/00514 , A61F2310/00532 , A61F2310/00544 , A61F2310/00562 , A61F2310/00976
Abstract: A vertebral body spacer of the present invention is used by being inserted between a vertebral body and a vertebral body (intervertebral space). The vertebral body spacer has a block body constituted of titanium or a titanium alloy as a main component thereof, and provided with a pair of contact surfaces to be made contact with the vertebral body and the vertebral body. The block body includes needle parts formed into a needle shape having both end portions and a porous part having through holes passing through the porous part in a thickness direction thereof, and a porosity of at least a surface of the porous part is larger than a porosity of each of the needle parts. The needle parts are inserted into the through holes so that the both end portions are projected from the contact surfaces.
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Patent Agency Ranking
公开(公告)号：US20130274886A1
公开(公告)日：2013-10-17
申请号：US13884439
申请日：2011-11-09
Applicant: Toshio Matsumoto , Yuzo Daigo , Shinichi Ohmori , Komei Kato
Inventor： Toshio Matsumoto , Yuzo Daigo , Shinichi Ohmori , Komei Kato
IPC: A61F2/44
CPC classification number: A61F2/442 , A61F2/4465 , A61F2002/30011 , A61F2002/30013 , A61F2002/30471 , A61F2002/30472 , A61F2002/30492 , A61F2002/30616 , A61F2002/30841 , A61F2002/30892 , A61F2002/30967 , A61F2002/30968 , A61F2002/3097 , A61F2002/30971 , A61F2002/448 , A61F2310/00023 , A61F2310/00431 , A61F2310/00443 , A61F2310/00485 , A61F2310/00491 , A61F2310/00497 , A61F2310/00514 , A61F2310/00532 , A61F2310/00544 , A61F2310/00562 , A61F2310/00976
Abstract: A vertebral body spacer of the present invention is used by being inserted between a vertebral body and a vertebral body (intervertebral space). The vertebral body spacer has a block body constituted of titanium or a titanium alloy as a main component thereof, and provided with a pair of contact surfaces to be made contact with the vertebral body and the vertebral body. The block body includes dense sheets having a dense part on at least a surface thereof and porous sheets having a porous part on at least a surface thereof. The porous part has a larger porosity than a porosity of the dense part. Each of the porous sheets is sandwiched between the pair of dense sheets. According to the present invention, it is possible to maintain an appropriate size between the vertebral bodies (intervertebral space).
Abstract translation: 通过插入椎体和椎体（椎间空间）来使用本发明的椎体间隔件。 椎体间隔物具有由钛或钛合金作为其主要成分构成的块体，并且具有与脊椎体和椎体接触的一对接触面。 块体包括在至少其表面上具有致密部分的致密片材，以及在至少其表面上具有多孔部分的多孔片材。 多孔部分具有比致密部分的孔隙率更大的孔隙率。 每个多孔片夹在一对致密片之间。 根据本发明，可以在椎体之间保持适当的尺寸（椎间空间）。
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公开(公告)号：US09730795B2
公开(公告)日：2017-08-15
申请号：US14319223
申请日：2014-06-30
Inventor： Pierre Descouts , Björn-Owe Aronsson , Michael Grätzel , Carine Viornery , Peter Péchy
IPC: A61F2/28 , A61C8/00 , A61F2/30 , A61L27/06 , A61L27/10 , A61L27/32 , C07F9/38 , C07F9/40 , C07F9/572 , C07F9/58 , C07F9/6506 , C07F9/6561 , A61F2/00
CPC classification number: A61F2/28 , A61C8/0012 , A61C2008/0046 , A61F2/0095 , A61F2/30767 , A61F2310/00017 , A61F2310/00023 , A61F2310/00029 , A61F2310/00047 , A61F2310/00053 , A61F2310/00059 , A61F2310/00089 , A61F2310/00095 , A61F2310/00131 , A61F2310/00401 , A61F2310/00407 , A61F2310/00413 , A61F2310/00431 , A61F2310/00443 , A61F2310/00449 , A61F2310/00485 , A61F2310/00491 , A61F2310/00544 , A61F2310/00598 , A61F2310/00616 , A61F2310/0073 , A61F2310/00748 , A61F2310/00796 , A61F2310/00856 , A61F2310/0088 , A61F2310/00928 , A61F2310/00976 , A61L27/06 , A61L27/10 , A61L27/32 , A61L2430/02 , C07F9/3808 , C07F9/3843 , C07F9/3865 , C07F9/3873 , C07F9/4046 , C07F9/572 , C07F9/58 , C07F9/6506 , C07F9/6561
Abstract: Endosseous implant to be applied to a human or animal bone, wherein the surface of the implant is made from titanium or a titanium alloy, said implant having a smooth or rough surface texture, which is characterized in that said surface has been treated with at least one selected organic phosphonate compound or a pharmaceutically acceptable salt or ester or an amide thereof; process for producing said implants.
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公开(公告)号：USRE43793E1
公开(公告)日：2012-11-06
申请号：US13213472
申请日：2001-11-19
Applicant: Pierre Descouts , Bjorn-Owe Aronsson , Michael Gratzel , Carine Viorney , Peter Pechy
Inventor： Pierre Descouts , Bjorn-Owe Aronsson , Michael Gratzel , Carine Viorney , Peter Pechy
CPC classification number: A61F2/28 , A61C8/0012 , A61C2008/0046 , A61F2/0095 , A61F2/30767 , A61F2310/00017 , A61F2310/00023 , A61F2310/00029 , A61F2310/00047 , A61F2310/00053 , A61F2310/00059 , A61F2310/00089 , A61F2310/00095 , A61F2310/00131 , A61F2310/00401 , A61F2310/00407 , A61F2310/00413 , A61F2310/00431 , A61F2310/00443 , A61F2310/00449 , A61F2310/00485 , A61F2310/00491 , A61F2310/00544 , A61F2310/00598 , A61F2310/00616 , A61F2310/0073 , A61F2310/00748 , A61F2310/00796 , A61F2310/00856 , A61F2310/0088 , A61F2310/00928 , A61F2310/00976 , A61L27/06 , A61L27/10 , A61L27/32 , A61L2430/02 , C07F9/3808 , C07F9/3843 , C07F9/3865 , C07F9/3873 , C07F9/4046 , C07F9/572 , C07F9/58 , C07F9/6506 , C07F9/6561
Abstract: Endosseous implant to be applied to a human or animal bone, wherein the surface of the implant is made from titanium or a titanium alloy, said implant having a smooth or rough surface texture, which is characterized in that said surface has been treated with at least one selected organic phosphonate compound or a pharmaceutically acceptable salt or ester or an amide thereof; process for producing said implants.
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公开(公告)号：US20100234900A1
公开(公告)日：2010-09-16
申请号：US12788815
申请日：2010-05-27
Applicant: Pierre Descouts , Björn-Owe Aronsson , Michael Grätzel , Carine Viornery , Peter Péchy
Inventor： Pierre Descouts , Björn-Owe Aronsson , Michael Grätzel , Carine Viornery , Peter Péchy
CPC classification number: A61F2/28 , A61C8/0012 , A61C2008/0046 , A61F2/0095 , A61F2/30767 , A61F2310/00017 , A61F2310/00023 , A61F2310/00029 , A61F2310/00047 , A61F2310/00053 , A61F2310/00059 , A61F2310/00089 , A61F2310/00095 , A61F2310/00131 , A61F2310/00401 , A61F2310/00407 , A61F2310/00413 , A61F2310/00431 , A61F2310/00443 , A61F2310/00449 , A61F2310/00485 , A61F2310/00491 , A61F2310/00544 , A61F2310/00598 , A61F2310/00616 , A61F2310/0073 , A61F2310/00748 , A61F2310/00796 , A61F2310/00856 , A61F2310/0088 , A61F2310/00928 , A61F2310/00976 , A61L27/06 , A61L27/10 , A61L27/32 , A61L2430/02 , C07F9/3808 , C07F9/3843 , C07F9/3865 , C07F9/3873 , C07F9/4046 , C07F9/572 , C07F9/58 , C07F9/6506 , C07F9/6561
Abstract: Endosseous implant to be applied to a human or animal bone, wherein the surface of the implant is made from titanium or a titanium alloy, said implant having a smooth or rough surface texture, which is characterized in that said surface has been treated with at least one selected organic phosphonate compound or a pharmaceutically acceptable salt or ester or an amide thereof; process for producing said implants.
Abstract translation: 骨质植入物应用于人或动物骨，其中所述植入物的表面由钛或钛合金制成，所述植入物具有光滑或粗糙的表面纹理，其特征在于，所述表面至少已被处理 一种选择的有机膦酸酯化合物或其药学上可接受的盐或酯或其酰胺; 用于生产所述植入物的方法。
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公开(公告)号：US07727540B2
公开(公告)日：2010-06-01
申请号：US10432026
申请日：2001-11-19
Applicant: Pierre Descouts , Björn-Owe Aronsson , Michael Grätzel , Carine Viornery , Peter Péchy
Inventor： Pierre Descouts , Björn-Owe Aronsson , Michael Grätzel , Carine Viornery , Peter Péchy
CPC classification number: A61F2/28 , A61C8/0012 , A61C2008/0046 , A61F2/0095 , A61F2/30767 , A61F2310/00017 , A61F2310/00023 , A61F2310/00029 , A61F2310/00047 , A61F2310/00053 , A61F2310/00059 , A61F2310/00089 , A61F2310/00095 , A61F2310/00131 , A61F2310/00401 , A61F2310/00407 , A61F2310/00413 , A61F2310/00431 , A61F2310/00443 , A61F2310/00449 , A61F2310/00485 , A61F2310/00491 , A61F2310/00544 , A61F2310/00598 , A61F2310/00616 , A61F2310/0073 , A61F2310/00748 , A61F2310/00796 , A61F2310/00856 , A61F2310/0088 , A61F2310/00928 , A61F2310/00976 , A61L27/06 , A61L27/10 , A61L27/32 , A61L2430/02 , C07F9/3808 , C07F9/3843 , C07F9/3865 , C07F9/3873 , C07F9/4046 , C07F9/572 , C07F9/58 , C07F9/6506 , C07F9/6561
Abstract: Endosseous implant to be applied to a human or animal bone, wherein the surface of the implant is made from titanium or a titanium alloy, said implant having a smooth or rough surface texture, which is characterized in that said surface has been treated with at least one selected organic phosphonate compound or a pharmaceutically acceptable salt or ester or an amide thereof; process for producing said implants.
Abstract translation: 骨质植入物应用于人或动物骨，其中所述植入物的表面由钛或钛合金制成，所述植入物具有光滑或粗糙的表面纹理，其特征在于，所述表面至少已被处理 一种选择的有机膦酸酯化合物或其药学上可接受的盐或酯或其酰胺; 用于生产所述植入物的方法。
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