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    EDIBLE PRODUCT CONTAINING BENEFICIAL BACTERIA
    1.
    发明申请
    EDIBLE PRODUCT CONTAINING BENEFICIAL BACTERIA 审中-公开
    食用含有益菌的产品

    公开(公告)号：US20090035288A1

    公开(公告)日：2009-02-05

    申请号：US11989059

    申请日：2006-06-29

    申请人： Ruud Albers ,  Stanley Brul ,  Adrianus Marinus Ledeboer ,  Willem Maarten Meijer

    发明人： Ruud Albers ,  Stanley Brul ,  Adrianus Marinus Ledeboer ,  Willem Maarten Meijer

    IPC分类号： A61K35/74

    CPC分类号： A23C9/12 ,  A23G9/00 ,  A23G2200/02

    摘要： The present invention provides a method of preparing an edible product comprising non-viable bacteria providing a health benefit, the method comprising subjecting viable bacteria to at least two sub-lethal treatments to obtain the non-viable bacteria providing a health benefit, each sub-lethal treatment on its own not being sufficient to render the bacteria non-viable. The method porvides non-viable bacteria providing health benefits but which can conveniently be incorporated into a range of edible products.

    摘要翻译： 本发明提供一种制备包含提供健康益处的非活细菌的食用产品的方法，所述方法包括将活细菌经受至少两次次致死处理以获得提供健康益处的非存活细菌， 致命的治疗本身不足以使细菌不可行。 该方法培养提供健康益处的非活细菌，但可方便地并入一系列可食用产品中。

    Edible product containing beneficial moulds and/or yeasts
    2.
    发明申请
    Edible product containing beneficial moulds and/or yeasts 审中-公开
    含有有益霉菌和/或酵母的食用产品

    公开(公告)号：US20090123608A1

    公开(公告)日：2009-05-14

    申请号：US11989062

    申请日：2006-06-27

    申请人： Ruud Albers ,  Adrianus Marinus Ledeboer ,  Stanley Brul

    发明人： Ruud Albers ,  Adrianus Marinus Ledeboer ,  Stanley Brul

    IPC分类号： A23L1/30 ,  A23L1/28

    CPC分类号： A23G9/00 ,  A23C9/12 ,  A23G2200/02

    摘要： The present invention provides a method of preparing an edible product comprising non-viable moulds and/or yeasts that are substantially structurally intact and which provide a health benefit, the method comprising subjecting viable moulds and/or yeasts to at least two sub-lethal treatments to obtain the non-viable moulds and/or yeasts providing a health benefit, each sub-lethal treatment on its own not being sufficient to render the moulds and/or yeasts non-viable.

    摘要翻译： 本发明提供了一种制备可食用产品的方法，所述食用产品包含基本上在结构上完整无损并且提供健康益处的非存活霉菌和/或酵母，所述方法包括将存活霉菌和/或酵母经受至少两种次致死处理 为了获得提供健康益处的不可行的霉菌和/或酵母，其本身的每种亚致死治疗不足以使霉菌和/或酵母不能存活。

    Heavy chain and single domain antibodies
    7.
    发明授权
    Heavy chain and single domain antibodies 失效
    重链和单结构域抗体

    公开(公告)号：US08105592B2

    公开(公告)日：2012-01-31

    申请号：US11791456

    申请日：2005-11-03

    申请人： Leo Gerardus Joseph Frenken ,  Lars-Gõran Lennart Hammarström ,  Adrianus Marinus Ledeboer

    发明人： Leo Gerardus Joseph Frenken ,  Lars-Gõran Lennart Hammarström ,  Adrianus Marinus Ledeboer

    IPC分类号： A61K35/66 ,  A61K39/395

    CPC分类号： A23L2/39 ,  A23F3/14 ,  A23F3/34 ,  A23G9/363 ,  A23L2/52 ,  A23L7/126 ,  A23L27/60 ,  A23L33/135 ,  A23L33/18 ,  A23L33/195 ,  A23V2002/00 ,  A23Y2220/17 ,  A61K9/0056 ,  A61K9/1652 ,  A61K2039/505 ,  C07K16/10 ,  C07K2317/22 ,  C07K2317/569 ,  C07K2317/622 ,  A23V2250/5434

    摘要： The present invention relates to heavy chain immunoglobulins or fragments thereof of the VHH or VNAR type, or domain antibodies (dAbs) of the heavy or light chains of immunoglobulins or fragments thereof, suitable for use in the management of infections, in particular of the gastrointestinal tract. The present invention also relates to a delivery system comprising these heavy chain immunoglobulins or functional fragments thereof of the VHH or VNAR type, or domain antibodies (dAbs) of the heavy or light chains of immunoglobulins or fragments thereof, and hosts comprising expression vectors encoding for these heavy chain immunoglobulins or functional fragments thereof of the VHH or VNAR type, or domain antibodies (dAbs) of the heavy or light chains of immunoglobulins or fragments thereof. The invention also relates to food products and pharmaceutical preparations comprising the delivery system, and methods for the preparation of food products according to the invention.

    摘要翻译： 本发明涉及VHH或VNAR型的重链免疫球蛋白或其片段或免疫球蛋白或其片段的重链或轻链的结构域抗体（dAb），其适用于治疗感染，特别是胃肠道 道。 本发明还涉及包含VHH或VNAR型的这些重链免疫球蛋白或其功能片段或免疫球蛋白或其片段的重链或轻链的结构域抗体（dAb）的递送系统，以及包含编码 VHH或VNAR型的这些重链免疫球蛋白或其功能片段，或免疫球蛋白或其片段的重链或轻链的结构域抗体（dAb）。 本发明还涉及包含递送系统的食品和药物制剂以及用于制备根据本发明的食品的方法。