摘要:
Thus, a primary aspect of the present invention relates to a method for the fractionation of a protein-containing mixture wherein the protein-containing mixture is selected from the group consisting of milk, milk derived products, milk derived raw materials, vegetable derived products, vegetable derived extracts, fruit derived products, fruit derived extracts, fish derived products, and fish derived extracts, said method comprising the steps of: a) optionally adjusting the pH of the mixture; b) applying said mixture to an adsorption column comprising an adsorbent, said adsorbent comprises a particle with at least one high density non-porous core, surrounded by a porous material, the adsorbent having a particle density of at least 1.5 g/ml and a mean particle size of at most 150 μm; c) optionally washing the column; d) eluting at least one protein from the adsorbent.
摘要:
The present invention relates to a food composition for stimulating growth, comprising a fraction isolated from whey derived from mammalian colostrum or milk. More particularly, the present invention relates to a food composition for stimulating growth, comprising a fraction isolated from mammalian whey, wherein the fraction was removed α-lactoalbumin and β-lactoglobulin from the whey and had a molecular weight of 1-30 kD, as well as a method for stimulating growth, which comprises administering the food composition to mammals in need thereof, and a use of the isolated fraction for preparing the growth-stimulating food composition.
摘要:
The present invention relates to complexes consisting of immunoglobulins and polysaccharides for oral and transmucosal use.The polysaccharides comprised in the complexes according to the invention form an envelope which protects and carries immunoglobulins allowing their systemic absorption through the gastric and mucosal district. Immunoglobulins have a different specificity depending on the required therapeutic effect. They are used in passive immunoprophylaxis for the prevention or therapy of infections caused by pathogenic agents such as virus, bacteria, parasites, or they are used in the modulation of endogenous bio-chemical balances, or in the detoxification from drugs of abuse, medicines, toxins.
摘要:
The present invention provides compositions and methods for making and using antibodies. A pharmaceutical composition of the invention comprises a selected antigen and a Candida spp. antigen. Selected antigens include, for example, antigens derived from bacteria, yeasts, rickettsias, protozoas, viruses, parasites, and components or fragments thereof. Preferred compositions disclosed include antigens selected from Cryptosporidium spp. and Clostridium spp. The invention further provides for immunizing an animal with a composition of the invention to prepare a composition of immunoglobulins reactive with the selected antigen. The composition of immunoglobulins can be included in nutraceuticals that are ingested or administered enterally.
摘要:
A composition for restoring and maintaining gastrointestinal health comprises 40-60% by weight of an immunoglobulin composition comprising concentrated immunologically active immunoglobulins and 40-60% by weight of soluble dietary fiber selected from inulin, fructo-oligosaccharides, pectin, guar gum, and mixtures thereof. The immunoglobulin and fiber-containing composition can optionally contain one or more of a beneficial human intestinal microorganism, components of a non-immune natural defense system, an iron-sequestering molecule, and gluconic acid. Preferred beneficial human intestinal microorganisms include lactobacilli and bifidobacteria. The immunologically active immunoglobulins are preferably purified from bovine milk, milk products, or whey. Methods of use are also described.
摘要:
A composition for restoring and maintaining gastrointestinal health comprises 40-60% by weight of an immunoglobulin composition comprising concentrated immunologically active immunoglobulins and 40-60% by weight of soluble dietary fiber selected from inulin, fructo-oligosaccharides, pectin, guar gum, and mixtures thereof. The immunoglobulin and fiber-containing composition can optionally contain one or more of a beneficial human intestinal microorganism, components of a non-immune natural defense system, an iron-sequestering molecule, and gluconic acid. Preferred beneficial human intestinal microorganisms include lactobacilli and bifidobacteria. The immunologically active immunoglobulins are preferably purified from bovine milk, milk products, or whey. Methods of use are also described.
摘要:
The present invention relates to a feed or food product composition which comprises a mixture of bovine colostrum, comprising bioactive components, and organic particulate matter having a size between 0.3 and 7 mm in diameter. The composition is especially adapted to deliver the mixture of bioactive bovine colostrum components to the digestive tract of a mammal.
摘要:
The present invention related to heavy chain immunoglobulins or fragments thereof of the VHH or VNAR type, or domain antibodies (dAbs) of the heavy or light chains of immunoglobulins or fragments thereof, suitable for use in the management of infections, in particular gastrointestinal tract. The present invention also relates to a delivery system comprising these heavy chain immunoglobulins or functional fragments thereof of the VHH or VNAR type, or domain antibodies (dAbs) of the heavy or light chains of immunoglobulins or fragments thereof, and hosts comprising expression vectors encoding for these heavy chain immunoglobulins or functional fragments thereof of the VHH or VNAR type, or domain antibodies (dAbs) of the heavy or light chains of immunoglobulins or fragments thereof. The invention also related to food products and pharmaceutical preparations comprising the delivery system, and method for the preparation of food products according to the invention.
摘要:
The invention relates to the treatment of intestinal barrier function disorders involving administration of a selected colostrum comprising more than 25 weight % undenatured immunoglobulin G(IgG) based on the weight of total protein content of said colostrum to a subject. The invention further relates to compositions comprising colostrum and indigestible dietary fibers wherein the colostrum comprises more than 25 weight % undenatured immunoglobulin G based on the weight of total protein content of said colostrum.
摘要:
The present invention relates to a feed or food product composition which comprises a mixture of bovine colostrum, comprising bioactive components, and organic particulate matter having a size between 0.3 and 7 mm in diameter. The composition is especially adapted to deliver the mixture of bioactive bovine colostrum components to the digestive tract of a mammal.