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公开(公告)号:US20200041780A1
公开(公告)日:2020-02-06
申请号:US16338674
申请日:2017-10-26
Applicant: SCOPIO LABS LTD.
Inventor: Erez NA'AMAN , Michael Shimon ILUZ , Itai HAYUT
IPC: G02B21/36 , G02B21/00 , G06T7/11 , G06F16/955
Abstract: Access to microscope images while a sample is scanned or images are generated or uploaded can decrease an amount of time that a user waits to view a region of interest of an image. A processor can be configured to allow a remote user to access a portion of an image at full or partial resolution while other portions of the sample are being scanned, or while one or more images are generated or uploaded at full or partial resolution. A processor stored locally with the microscope can be configured to allow a remote user to access a completed scan over the internet prior to the scan being fully uploaded over a network such as the internet to a remote server. In some embodiments, a processor may be coupled to a microscope, a user device, or a remote server.
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公开(公告)号:US20210392304A1
公开(公告)日:2021-12-16
申请号:US17304331
申请日:2021-06-18
Applicant: SCOPIO LABS LTD.
Inventor: Ben LESHEM , Eran SMALL , Itai HAYUT , Erez NA'AMAN , Eyal BEN-BASSAT
Abstract: A microscope for computational imaging may include an illumination source configured to illuminate a sample with a plurality of wavelengths, an image sensor, an objective lens to image the sample onto the image sensor, and a processor operatively coupled to the illumination assembly and the image sensor. The processor may be configured to acquire a first image dataset from the sample illuminated using a first set of illumination conditions at a first wavelength. The processor may also be configured to acquire a second image dataset from the sample illuminated using a second set of illumination conditions having a second number of illumination conditions at a second wavelength. The second set of illumination conditions comprises fewer illumination conditions than the first set in order to decrease acquisition time. The processor may be configured to combine the first and second image datasets into a computationally reconstructed image of the sample.
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公开(公告)号:US20200278530A1
公开(公告)日:2020-09-03
申请号:US16875721
申请日:2020-05-15
Applicant: SCOPIO LABS LTD.
Inventor: Ittai MADAR , Eran SMALL , Itai HAYUT , Erez NA'AMAN
Abstract: A microscope comprising an illumination assembly, an image capture device and a processor can be configured to selectively identify regions of a sample comprising artifacts or empty space. By selectively identifying regions of the sample that have artifacts or empty space, the amount of time to generate an image of the sample and resources used to generate the image can be decreased substantially while providing high resolution for appropriate regions of the computational image. The processor can be configured to change the imaging process in response to regions of the sample that comprises artifacts or empty space. The imaging process may comprise a higher resolution process to output higher resolution portions of the computational image for sample regions comprising valid sample material, and a lower resolution process to output lower resolution portions of the computational image for sample regions comprising valid sample material.
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公开(公告)号:US20230384205A1
公开(公告)日:2023-11-30
申请号:US18248566
申请日:2021-11-09
Applicant: SCOPIO LABS LTD.
Inventor: Shahar KARNY , Ben LESHEM , Erez NA'AMAN , Eran SMALL , Itai HAYUT
CPC classification number: G01N15/1434 , G06T7/0012 , G06T3/4053 , G06V20/698 , G06V20/693 , G02B21/008 , G01N2015/008
Abstract: A microscope system for full field morphology analysis may include an optical scanning apparatus to scan the sample with an effective numerical aperture of at least 0.8, and a processor coupled to the scanning apparatus. The processor may be configured to: scan the sample with the optical scanning apparatus to produce a plurality of images of the sample, the plurality of images comprising at least 500 blood cells, analyze the plurality of images to determine at least 10 morphology parameters for each of the at least 500 blood cells, and output the at least 10 morphology parameters. The microscope system may include a display for presenting data. Various other systems and methods are provided.
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公开(公告)号:US20200278362A1
公开(公告)日:2020-09-03
申请号:US16875665
申请日:2020-05-15
Applicant: SCOPIO LABS LTD.
Inventor: Itai HAYUT , Erez NA'AMAN , Eran SMALL
Abstract: A microscope system may comprise a plurality of microscope modules, a cassette for holding a plurality of slides, a slide loader configured to move the plurality of slides between the cassette and the plurality of microscope modules, and a processor coupled to the slide loader. The processor may be configured with instructions which, when executed, cause the slide loader to move a slide into or from a selected microscope module among the plurality of microscope modules. Various other methods, systems, and computer-readable media are also disclosed.
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公开(公告)号:US20180348500A1
公开(公告)日:2018-12-06
申请号:US15774881
申请日:2016-11-10
Applicant: SCOPIO LABS LTD.
Inventor: Erez NAAMAN, III , Michael Shimon ILUZ , Itai HAYUT
CPC classification number: G02B21/367 , G06F19/00 , G06K9/00134 , G06K9/2081 , G06T3/4053 , G16H10/40
Abstract: Microscopes and methods for processing images of a sample are disclosed. In one implementation, a microscope includes an illumination assembly configured to illuminate the sample under two or more different illumination conditions. The microscope further includes at least one image capture device configured to capture image information associated with the sample and at least one controller. The at least one controller is programmed to receive, from the at least one image capture device, a plurality of images associated with the sample. At least a first portion of the plurality of images is associated with a first region of the sample, and a second portion of the plurality of images is associated with a second region of the sample. The at least one controller is further programmed to initiate a first computation process to generate a high resolution image of the first region by combining image information selected from the first portion of the plurality of images; receive, after initiating the first computation process and before completing the first computation process, a request associated with prioritizing a second computation process for generating a high resolution image of the second region; and initiate, after receiving the request, the second computation process to generate the high resolution image of the second region by combining image information selected from the second portion of the plurality of images.
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公开(公告)号:US20180120553A1
公开(公告)日:2018-05-03
申请号:US15795150
申请日:2017-10-26
Applicant: Scopio Labs Ltd.
Inventor: Ben LESHEM , Itai HAYUT , Erez NA'AMAN , Eran SMALL
CPC classification number: G02B21/365 , G01N21/17 , G01N21/25 , G02B21/14 , G02B21/34 , G02B21/367 , G16H30/40
Abstract: Disclosed herein are systems and methods for constructing an image of a sample using a plurality of images acquired under multiple illumination conditions. In some cases, a microscope may include an image capture device, an illumination assembly, and a processor configured to acquire a plurality of images of a sample and a fiducial marker under a plurality of different illumination conditions and to reconstruct a high resolution image in response to the plurality of images. The disclosure also provides a method for generating a high resolution image of a sample comprising acquiring a plurality of images of a sample and a fiducial marker under a plurality of different illumination conditions and reconstructing the high resolution image in response to the plurality of images.
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公开(公告)号:US20240369584A1
公开(公告)日:2024-11-07
申请号:US18771065
申请日:2024-07-12
Applicant: SCOPIO LABS LTD.
Inventor: Itai HAYUT , Erez NA'AMAN , Eran SMALL
Abstract: A microscope system may comprise a plurality of microscope modules, a cassette for holding a plurality of slides, a slide loader configured to move the plurality of slides between the cassette and the plurality of microscope modules, and a processor coupled to the slide loader. The processor may be configured with instructions which, when executed, cause the slide loader to move a slide into or from a selected microscope module among the plurality of microscope modules. Various other methods, systems, and computer-readable media are also disclosed.
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公开(公告)号:US20240085688A1
公开(公告)日:2024-03-14
申请号:US18514050
申请日:2023-11-20
Applicant: SCOPIO LABS LTD.
Inventor: Ittai MADAR , Eran SMALL , Itai HAYUT , Erez NA'AMAN
CPC classification number: G02B21/367 , G02B21/0084 , G02B21/125
Abstract: A microscope comprising an illumination assembly, an image capture device and a processor can be configured to selectively identify regions of a sample comprising artifacts or empty space. By selectively identifying regions of the sample that have artifacts or empty space, the amount of time to generate an image of the sample and resources used to generate the image can be decreased substantially while providing high resolution for appropriate regions of the computational image. The processor can be configured to change the imaging process in response to regions of the sample that comprises artifacts or empty space. The imaging process may comprise a higher resolution process to output higher resolution portions of the computational image for sample regions comprising valid sample material, and a lower resolution process to output lower resolution portions of the computational image for sample regions comprising valid sample material.
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公开(公告)号:US20230005281A1
公开(公告)日:2023-01-05
申请号:US17931271
申请日:2022-09-12
Applicant: SCOPIO LABS LTD.
Inventor: Ben LESHEM , Eran SMALL , Itai HAYUT , Erez NA'AMAN , Eyal BEN-BASSAT
Abstract: A microscope for adaptive sensing may comprise an illumination assembly, an image capture device configured to collect light from a sample illuminated by the assembly, and a processor. The processor may be configured to execute instructions which cause the microscope to capture, using the image capture device, an initial image set of the sample, identify, in response to the initial image set, an attribute of the sample, determine, in response to identifying the attribute, a three-dimensional (3D) process for sensing the sample, and generate, using the determined 3D process, an output image set comprising more than one focal plane. Various other methods, systems, and computer-readable media are also disclosed.
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