公开(公告)号：US20170183618A1

公开(公告)日：2017-06-29

申请号：US15324408

申请日：2015-07-27

Applicant: SEKISUI CHEMICAL CO., LTD.

Inventor： Kanetomo SATOU ,  Norihide NISHIYAMA ,  Kokoro HAMACHI ,  Tetsuya ISHII

IPC: C12M1/00 ,  C12P7/08

Abstract: The present invention provides an apparatus and a method which can be used for producing an organic substance effectively from a synthesis gas obtained from a waste incinerator. The apparatus 1 for producing an organic substance from waste, comprises a synthesis gas generation furnace 11, a fermenter 13, and a nutrient feeder. The synthesis gas generation furnace 11 generates a synthesis gas by partial oxidation of waste. The fermenter 13 contains a microorganism which produces an organic substance from the synthesis gas. The nutrient feeder 12 feeds a solid or liquid nutrient to the fermenter 13 when an amount of the synthesis gas supplied to the fermenter 13 is insufficient.

公开(公告)号：US20180334657A1

公开(公告)日：2018-11-22

申请号：US15777754

申请日：2015-11-30

Applicant: SEKISUI CHEMICAL CO., LTD.

Inventor： Masahiro FURUTANI ,  Norihide NISHIYAMA ,  Kazufumi KAWABATA

IPC: C12N9/04 ,  C12P5/00 ,  C12N9/88 ,  C12N9/02 ,  C12N15/90

CPC classification number: C12N9/0006 ,  C12N9/0008 ,  C12N9/88 ,  C12N15/00 ,  C12N15/902 ,  C12P5/00 ,  C12P5/002 ,  C12P5/007 ,  C12P5/02 ,  C12Y101/01001 ,  C12Y101/01034 ,  C12Y101/01088 ,  C12Y102/0101 ,  C12Y402/03027 ,  C12Y402/03051 ,  Y02E50/343

Abstract: A recombinant cell having a function of synthesizing acetyl-CoA from methyltetrahydrofolate, carbon monoxide, and CoA, including: a gene that expresses an exogenous NAD(P)H consumption pathway, the gene being expressed in the recombinant cell, wherein expression in at least one of endogenous NAD(P)H consumption pathways of the recombinant cell is down-regulated, and the endogenous NAD(P)H consumption pathway is different from the exogenous NAD(P)H consumption pathway, and the recombinant cell produces an organic compound having 4 or more carbon atoms from at least one selected from the group consisting of carbon monoxide and carbon dioxide via the exogenous NAD(P)H consumption pathway.

公开(公告)号：US20170306286A1

公开(公告)日：2017-10-26

申请号：US15511800

申请日：2015-09-14

Applicant: SEKISUI CHEMICAL CO., LTD.

Inventor： Tetsuya ISHII ,  Kanetomo SATOU ,  Yoji FUJIMORI ,  Kokoro HAMACHI ,  Norihide NISHIYAMA

IPC: C12M1/34 ,  C12N1/20 ,  C12M1/02 ,  C12M1/00 ,  C12P7/06

CPC classification number: C12M41/36 ,  C12M1/00 ,  C12M1/06 ,  C12M23/02 ,  C12M27/00 ,  C12M29/00 ,  C12M29/04 ,  C12M33/14 ,  C12M41/14 ,  C12M41/18 ,  C12N1/00 ,  C12N1/20 ,  C12P7/065 ,  Y02E50/17

Abstract: Gas-utilizing microorganisms are stably cultured regardless of variations in a supply flow rate of a substrate gas. Gas-utilizing microorganisms 9 are cultured in a culture solution 2 in a culture tank 10. A substrate gas containing CO and H2 or the like is supplied to the culture tank 10 and is dissolved in the culture solution 2. When a supply flow rate of the substrate gas or predetermined constituents of the substrate gas to the culture tank 10 becomes a predetermined value or lower, a culture solution 2a is rapidly discharged from the culture tank 10.

公开(公告)号：US20210054418A1

公开(公告)日：2021-02-25

申请号：US17040125

申请日：2019-03-20

Applicant: SEKISUI CHEMICAL CO., LTD.

Inventor： Norihide NISHIYAMA ,  Kanetomo SATO

IPC: C12P7/06

Abstract: Provided is a method for producing an organic substance, in which an organic material (metabolite) derived from a microorganism is reduced while retaining a nutritive substance in an organic substance-containing solution discharged from a fermentation tank containing the microorganism, whereby various nutritional elements contained in the organic substance-containing solution can be reused with high efficiency. A method for producing an organic substance by the microbial fermentation of a synthetic gas containing at least carbon monoxide, the method comprising a synthetic gas supply step of supplying the synthetic gas into a fermentation tank containing a microorganism, a fermentation step of subjecting the synthetic gas to microbial fermentation in the fermentation tank, an aerobic fermentation treatment step of subjecting at least a portion of a liquid produced in the fermentation step to an aerobic fermentation treatment in a liquid waste treatment unit, and a recycling step of supplying a liquid produced in the aerobic fermentation treatment step to the fermentation tank, wherein the aerobic fermentation treatment step is carried out in the presence of a nitrifying bacterium inhibitor.

公开(公告)号：US20180023098A1

公开(公告)日：2018-01-25

申请号：US15549739

申请日：2016-02-10

Applicant: SEKISUI CHEMICAL CO., LTD.

Inventor： Masahiro FURUTANI ,  Kazufumi KAWABATA ,  Norihide NISHIYAMA

IPC: C12P5/02 ,  C12P5/00 ,  C12N9/88 ,  C12N15/62 ,  C12N9/90

CPC classification number: C12P5/026 ,  C07K14/00 ,  C07K19/00 ,  C12N9/00 ,  C12N9/88 ,  C12N9/90 ,  C12N15/09 ,  C12N15/62 ,  C12P5/00 ,  C12P5/002 ,  C12P5/02 ,  C12R1/145 ,  C12Y402/03027 ,  C12Y402/03052 ,  C12Y502/01008 ,  Y02E50/343

Abstract: Provided is a nucleic acid encoding a fusion protein, the fusion protein including a first protein selected from the group consisting of isoprene synthase and cyclic terpene synthase, and a FKBP family protein linked to the first protein. Provided is a fusion protein encoded by the nucleic acid. Provided is a recombinant cell including the nucleic acid and expressing the fusion protein. Further provided is a recombinant cell including a first nucleic acid encoding the first protein and a second nucleic acid encoding the FKBP family protein, and expressing the first protein and the FKBP family protein. As a host cell, a syngas-assimilating bacterium or a methanol assimilating bacterium can be used.