公开(公告)号：US20220375739A1

公开(公告)日：2022-11-24

申请号：US17697045

申请日：2022-03-17

Applicant: SHIMADZU CORPORATION

Inventor： Masaru NISHIGUCHI ,  Akiko IMAZU ,  Osamu FURUHASHI

IPC: H01J49/16 ,  H01J49/00 ,  H01J49/26

Abstract: In order to improve the ionization efficiency and ion collection efficiency in an ESI ion source to achieve a higher level of analysis sensitivity while improving the throughput of the analysis, one mode of the present invention provides an ion analyzer equipped with an ion source employing an electrospray ionization method, where the ion source (2) includes: a plurality of capillaries (211-218) configured to spray a supplied liquid sample in the same direction; one or more auxiliary electrodes (23, 231-328) arranged so as to be surrounded by the plurality of capillaries; and a voltage supplier (24) configured to apply, to the plurality of capillaries, a DC high voltage for which the potential of the one or more auxiliary electrodes is used as a reference.

公开(公告)号：US20200312647A1

公开(公告)日：2020-10-01

申请号：US16700032

申请日：2019-12-02

Applicant: SHIMADZU CORPORATION

Inventor： Akiko IMAZU ,  Motohide Yasuno ,  Yoshinori Arita ,  Takao Nakatomi

IPC: H01J49/06

Abstract: Provided is an ion transport device 1 including: a drift tube 10 having a plurality of ring-shaped electrodes 11 arranged in an axial direction; a housing 30 containing the drift tube 10; a drift-tube support member 21 supporting the drift tube 10 in relation to the housing 30; a detector 20 fixed to the drift tube 10 and configured to detect ions; and a vibration damper 22 provided on the drift-tube support member 21 and configured to absorb vibration which the drift-tube support member 21 receives from the housing 30. By such a configuration, an occurrence of noise in a detection signal of the detector 20 due to an influence of the vibration can be prevented.

公开(公告)号：US20180246061A1

公开(公告)日：2018-08-30

申请号：US15756137

申请日：2016-05-23

Applicant: SHIMADZU CORPORATION

Inventor： Akiko IMAZU ,  Hideaki IZUMI

IPC: G01N27/62 ,  H01J49/06 ,  H01J49/00

CPC classification number: G01N27/622 ,  G01N27/62 ,  H01J49/0031 ,  H01J49/06 ,  H01J49/061

Abstract: A gate electrode (10A) used as a shutter gate includes a pair of conductive fixture members (131, 132) made of metal and identical in size attached to the inside of a rectangular opening (12) of a ceramic base (11), along with insulating fixture members (141, 142) made of ceramic attached to the inner sides of the conductive fixture members. Two comb electrodes (151, 152) as one pair have connecting portions (151a, 152a) adhered to the conductive fixture members (131, 132) as well as thin-wire electrodes whose distal ends are adhered to the insulating fixture members (141, 142). By setting length L of the opening (12) and width D of the conductive fixture members (131, 132) to appropriate values according to the coefficient of thermal expansion of each of those members, the elongation of the electrodes which accompanies an increase in temperature can be balanced by the increase in the distance between the adhered positions of the electrodes to prevent the electrodes from being excessively taut or slack. Therefore, the drift region can be heated to a higher temperature than conventional levels to perform a high-accuracy, high-resolution analysis free from the influence of residual water vapor or similar particles.

公开(公告)号：US20180328886A1

公开(公告)日：2018-11-15

申请号：US15758609

申请日：2015-09-09

Applicant: SHIMADZU CORPORATION

Inventor： Motohide YASUNO ,  Akiko IMAZU

IPC: G01N27/68 ,  H01J49/10 ,  H01J49/40 ,  G01N27/62

CPC classification number: G01N27/68 ,  G01N27/622 ,  H01J49/10 ,  H01J49/40

Abstract: A first shutter gate is disposed at an entrance of a drift region, and a second shutter gate is disposed on the downstream side in an ion-drifting direction. In a high-resolution measurement mode, a controller (9) controls voltage generators to open the second shutter gate to collect ions into a pulsed form at the first shutter gate. In this mode, the controller controls the voltage generators to open the first shutter gate to collect ions into a pulsed form at the second shutter gate. In a zoom-in measurement mode where ions within a specified range of ion mobility are measured with high resolving power, the controller controls the voltage generators to open the first shutter gate for a short period of time, and then to open the second shutter gate for a short period of time after a lapse of a predetermined time period.

公开(公告)号：US20170148620A1

公开(公告)日：2017-05-25

申请号：US15310280

申请日：2014-05-14

Applicant: SHIMADZU CORPORATION

Inventor： Masaru NISHIGUCHI ,  Akiko IMAZU

IPC: H01J49/06 ,  H01J49/42 ,  H01J49/24 ,  H01J49/22

CPC classification number: H01J49/063 ,  H01J49/061 ,  H01J49/22 ,  H01J49/24 ,  H01J49/422

Abstract: An off-axis ion transport optical system (20) including a front-stage quadrupole ion guide (21), a rear-stage quadrupole ion guide (22), and an ion deflector (23) is disposed inside an intermediate vacuum chamber (2) in a stage next to an ionization chamber (1) maintained at an atmospheric pressure. Both of the quadrupole ion guides (21 and 22) have the same configuration as that of a conventional ion guide that transports ions while trapping the ions using a radio-frequency electric field. The ion deflector (23) includes a pair of parallel flat electrodes (231 and 232) and deflects ions using a direct-current electric field. By causing the deflected ions to reach the ion receiving range of the rear-stage quadrupole ion guide (22), it is possible to efficiency introduce ions while deflecting the ions. Meanwhile, the ions and neutral particles are separated from each other in the ion deflector (23). This provides an off-axis structure ion transport optical system that achieves a high ion transmission efficiency with a simple structure.

公开(公告)号：US20160189946A1

公开(公告)日：2016-06-30

申请号：US14898804

申请日：2013-06-17

Applicant: SHIMADZU CORPORATION

Inventor： Masaru NISHIGUCHI ,  Akiko IMAZU ,  Hiroki SAKAE

IPC: H01J49/06 ,  H01J49/40 ,  H01J49/00

CPC classification number: H01J49/063 ,  H01J49/005 ,  H01J49/062 ,  H01J49/401

Abstract: Within an intermediate vacuum chamber next to an ionization chamber maintained at atmospheric pressure, an electrode group of a radio-frequency carpet composed of a plurality of concentrically arranged ring electrodes is placed before a skimmer, with its central axis coinciding with that of an ion-passing hole. Each ring electrode has a circular radial sectional shape. Radio-frequency voltages with mutually inverted phases are applied to the ring electrodes neighboring each other in the radial direction. Additionally, a different level of direct-current voltage is applied to each ring electrode to create a potential which is sloped downward from the outer ring electrode to the inner ring electrode. The circular cross section of the electrode produces a steep pseudo-potential near the electrode and thereby increases the repulsive force which acts on the ions to repel them from the electrode.

Abstract translation: 在保持大气压的电离室旁的中间真空室内，将由多个同心布置的环形电极组成的射频毯的电极组放置在撇渣器之前，其中心轴线与离​​子 - 通孔。 每个环形电极具有圆形的径向截面形状。 具有相互反相的射频电压被施加到径向相邻的环形电极。 另外，将不同程度的直流电压施加到每个环形电极以产生从外环电极向内环电极向下倾斜的电位。 电极的圆形横截面在电极附近产生陡峭的伪电位，从而增加作用在离子上以从电极排斥它们的排斥力。