公开(公告)号：US10024789B2

公开(公告)日：2018-07-17

申请号：US15115362

申请日：2014-02-07

Applicant: SHIMADZU CORPORATION

Inventor： Kumiko Jingu ,  Masanori Fujiwara ,  Masami Tomita ,  Yutaka Kono

IPC: G01N21/41 ,  G01N30/74

Abstract: A differential refractometer including a measurement section for measuring the diffractive index difference between a sample cell and a reference cell by radiating light on a measurement cell and detecting light which has sequentially passed through the sample cell and the reference cell includes a mobile phase supply section for delivering a mobile phase in a sample introduction channel that is connected to the sample cell. The mobile phase supply section includes a mobile phase container for containing the mobile phase. The inside of the mobile phase container is continuously stirred by a stirring mechanism, and the composition of the mobile phase inside the mobile phase container is made uniform.

公开(公告)号：US11531010B2

公开(公告)日：2022-12-20

申请号：US16624436

申请日：2017-07-24

Applicant: Shimadzu Corporation

Inventor： Katsumasa Sakamoto ,  Masanori Fujiwara

IPC: B01D15/24 ,  B01D15/36 ,  B01D61/46 ,  B01D65/02 ,  G01N30/64

Abstract: An ion suppressor includes ion exchange membranes between a pair of electrodes. Regeneration liquid channels are provided in the spaces between the electrodes and the ion exchange membranes, and an eluent channel is provided between the ion exchange membranes. In the space between the electrode and the eluent channel, an element that increases the resistance in the voltage application direction is disposed. For example, ion permeable membranes are disposed in contact with the ion exchange membrane, thereby increasing the resistance in the voltage application direction.

公开(公告)号：US10041914B1

公开(公告)日：2018-08-07

申请号：US15612472

申请日：2017-06-02

Applicant: SHIMADZU CORPORATION

Inventor： Kumiko Jingu ,  Keisuke Ogawa ,  Masato Watanabe ,  Yusuke Nagai ,  Masanori Fujiwara ,  Tomoyuki Yamazaki

IPC: G01N21/00 ,  G01N30/74 ,  G01N21/59 ,  G01N30/02

Abstract: A degassing device 2 includes: a built-in absorbance measurement section 28 using an LED light source and measuring the intensity of light transmitted through a mobile phase passing through a flow cell; and a solenoid valve 26 switchable between two states with and without the mobile phase passed through a degassing tube 21. The passage-switching operation by the solenoid valve is performed so as to obtain detection signals of the transmitted light in the absorbance measurement section when the mobile phase drawn from a mobile phase container by a liquid-feeding pump 40 is passed through the degassing tube for degassing as well as when the mobile phase is not passed through the degassing tube for degassing. A signal processor 29 calculates the difference in absorbance based on those detection signals, estimates the degree of degassing based on that difference, and displays the result on a display unit 32.

公开(公告)号：US12031957B2

公开(公告)日：2024-07-09

申请号：US17442200

申请日：2019-03-27

Applicant: SHIMADZU CORPORATION

Inventor： Katsumasa Sakamoto ,  Masanori Fujiwara

IPC: G01N30/96 ,  B01D15/36 ,  G01N30/02

CPC classification number: G01N30/02 ,  B01D15/367 ,  G01N30/96

Abstract: First and second electrode liquid seal members are arranged between a first electrode and a second electrode. First and second ion exchange membranes are arranged between the first electrode liquid seal member and the second electrode liquid seal member. An eluent seal member is arranged between the first ion exchange membrane and the second ion exchange membrane. A plurality of first mesh members having different charge amounts are stacked in a first electrode liquid flow path of the first electrode liquid seal member. Each of the plurality of first mesh members is constituted by a first wire group composed of a plurality of first wires and a second wire group composed of a plurality of second wires crossing the first wire group. The plurality of first wire groups of the plurality of first mesh members respectively extend in different directions, and the plurality of second wire groups of the plurality of first mesh members respectively extend in different directions and extend in directions different from those of the plurality of first wire groups.

公开(公告)号：US11982653B2

公开(公告)日：2024-05-14

申请号：US17599768

申请日：2019-04-01

Applicant: SHIMADZU CORPORATION

Inventor： Katsumasa Sakamoto ,  Masanori Fujiwara

IPC: G01N30/38 ,  B01D15/36 ,  B01D15/42 ,  G01N30/02

CPC classification number: G01N30/38 ,  B01D15/361 ,  B01D15/426 ,  G01N2030/027

Abstract: First and second flow-path portions are opposite to each other, and communicate with each other such that a direction in which an eluent flows through the first flow-path portion and a direction in which an eluent flows through the second flow-path portion are opposite to each other. First and second electrode liquid flow paths are respectively opposite to the first and second flow-path portions. First and second electrode liquids are respectively supplied to the first and second electrode liquid flow paths, such that a direction in which the first electrode liquid flows through the first electrode liquid flow path is same as a direction in which an eluent flows through the first flow-path portion and a direction in which the second electrode liquid flows through the second electrode liquid flow path is same as a direction in which an eluent flows through the second flow-path portion.

公开(公告)号：US10101308B2

公开(公告)日：2018-10-16

申请号：US15074000

申请日：2016-03-18

Applicant: SHIMADZU CORPORATION

Inventor： Masanori Fujiwara

IPC: G01N21/05 ,  G01N21/41 ,  G01N30/74

Abstract: An embodiment of a refractive index detector includes a sample cell, a reference cell, a measurement section, a liquid inlet port, liquid outlet sections, and a switching mechanism. The inlet port leads to a sample cell inlet. A first outlet port and a second outlet port are for discharging a liquid. The switching mechanism includes a reference liquid supply mode for forming a channel for connecting a reference cell outlet to one of the first outlet port and the second outlet port while connecting a sample cell outlet to a reference cell inlet, and an analysis mode for forming a channel for connecting the sample cell outlet to one of the first outlet port and the second outlet port while sealing the reference cell outlet.

公开(公告)号：US09877368B2

公开(公告)日：2018-01-23

申请号：US15015810

申请日：2016-02-04

Applicant: SHIMADZU CORPORATION

Inventor： Yusuke Nagai ,  Keisuke Ogawa ,  Masato Watanabe ,  Kumiko Jingu ,  Masanori Fujiwara ,  Tomoyuki Yamazaki

IPC: H05B33/08 ,  G01N21/33

CPC classification number: H05B33/0851 ,  G01N21/33 ,  G01N2201/0621 ,  G01N2201/0638 ,  G01N2201/0692 ,  G01N2201/0695

Abstract: Provided is an optical analyzer for performing a feedback control on the amount of light emitted from an LED as a light source, in which the configuration of an optical system is made simple and the degree of freedom in optical system arrangement is secured. An optical member 2 for focusing most of light while discharging part of the light as unfocused light is provided on an optical path from a light casting unit 1 to a sample cell 3. The optical member 2 can be achieved with a simple configuration, for example, two ball lenses spaced apart by a predetermined distance from each other. The light focused by the optical member 2 is cast as measurement light into the sample cell 3. Meanwhile, a second photodetector 5 is arranged at a position where the unfocused light reaches. The second photodetector 5 generates a detection signal in accordance with the amount of light that has entered the second photodetector 5 as monitored light, and a drive current to be supplied to an LED is controlled through a drive current controlling unit 6 and a current source 7 such that the amount of light is maintained at a fixed level.

公开(公告)号：US20170010213A1

公开(公告)日：2017-01-12

申请号：US15115362

申请日：2014-02-07

Applicant: SHIMADZU CORPORATION

Inventor： Kumiko Jingu ,  Masanori Fujiwara ,  Masami Tomita ,  Yutaka Kono

IPC: G01N21/41 ,  G01N30/74

CPC classification number: G01N21/4133 ,  G01N30/74 ,  G01N2021/4146

Abstract: A differential refractometer including a measurement section for measuring the diffractive index difference between a sample cell and a reference cell by radiating light on a measurement cell and detecting light which has sequentially passed through the sample cell and the reference cell includes a mobile phase supply section for delivering a mobile phase in a sample introduction channel that is connected to the sample cell. The mobile phase supply section includes a mobile phase container for containing the mobile phase. The inside of the mobile phase container is continuously stirred by a stirring mechanism, and the composition of the mobile phase inside the mobile phase container is made uniform.

Abstract translation: 一种差分折射计，包括测量部分，用于通过在测量单元上照射光并检测已经顺次通过样品池和参考单元的光来测量样品池和参考单元之间的衍射指数差异，该测量部分包括用于 在连接到样品池的样品引入通道中提供流动相。 流动相供应部分包括用于容纳流动相的流动相容器。 流动相容器的内部通过搅拌机构连续搅拌，流动相容器内的流动相组成均匀。

公开(公告)号：US20160274074A1

公开(公告)日：2016-09-22

申请号：US15074000

申请日：2016-03-18

Applicant: SHIMADZU CORPORATION

Inventor： Masanori Fujiwara

IPC: G01N30/74 ,  G01N30/16 ,  G01N21/05 ,  G01N21/41

CPC classification number: G01N30/74 ,  G01N21/05 ,  G01N21/41 ,  G01N2201/061 ,  G01N2201/068 ,  G01N2030/626

Abstract: An embodiment of a refractive index detector includes a sample cell, a reference cell, a measurement section, a liquid inlet port, liquid outlet sections, and a switching mechanism. The inlet port leads to a sample cell inlet. A first outlet port and a second outlet port are for discharging a liquid. The switching mechanism includes a reference liquid supply mode for forming a channel for connecting a reference cell outlet to one of the first outlet port and the second outlet port while connecting a sample cell outlet to a reference cell inlet, and an analysis mode for forming a channel for connecting the sample cell outlet to one of the first outlet port and the second outlet port while sealing the reference cell outlet.

Abstract translation: 折射率检测器的一个实施例包括样品池，参考池，测量区，液体入口，液体出口区和切换机构。 入口通向样品池入口。 第一出口和第二出口用于排出液体。 开关机构包括用于形成用于将参考单元出口连接到第一出口和第二出口之一并将样本单元出口连接到参考单元入口的通道的参考液体供给模式，以及用于形成 通道，用于将样品池出口连接到第一出口和第二出口之一，同时密封参考池出口。