Abstract:
The present invention provides a medical analysis device and a cell analysis method, which can capture specific cells such as many types of cancer cells including cancer cells not expressing EpCAM and stem cells. Provided is a medical analysis device including a well portion, the well portion having a hydrophilic silane compound layer formed at least partly on the inner surface thereof.
Abstract:
Provided are a medical analysis device and a cell analysis method which can capture many cancer cells, including cancer cells not expressing EpCAM. A medical analysis device including a flow channel zone that includes a chamber zone, the inner surface of the flow channel zone being at least partially provided with a layer of a hydrophilic polymer having a thickness of 2 to 200 nm.
Abstract:
The present invention provides a method for surface-modifying a rubber vulcanizate or a thermoplastic elastomer, which can cost-effectively provide a variety of functions, such as remarkable sliding properties or biocompatibility, according to the application. The present invention relates to a method for surface-modifying a rubber vulcanizate or a thermoplastic elastomer as a modification target, the method including: step 1 of forming polymerization initiation points A on a surface of the modification target; step 2 of radically polymerizing a non-functional monomer starting from the polymerization initiation points A to grow non-functional polymer chains; step 3 of washing the modification target on which the non-functional polymer chains are grown; step 4 of forming polymerization initiation points B on a surface of the non-functional polymer chains; and step 5 of radically polymerizing a fluorine-containing functional monomer starting from the polymerization initiation points B to grow fluorine-containing functional polymer chains.
Abstract:
Provided are surface-modified metals such as metal medical devices e.g., guide wires, syringe needles, and metal tubes in medical devices or equipment, and methods for modifying a metal surface, wherein a lubricant layer is firmly bonded to the surface to impart lubricity to the surface and, further, improve the durability of the lubricant layer on the surface, thereby suppressing deterioration of the sliding properties. Included is a surface-modified metal having a surface at least partially treated by polymerization of a monomer in the presence of a thermal polymerization initiator.
Abstract:
The present invention provides metal medical devices which are provided with sliding properties (lubricity), low protein adsorption properties and low cell adsorption properties and further in which these properties are prevented from deteriorating. The present invention relates to a metal medical device having a surface at least partially treated with a copolymer C of a polymerizable silane compound A and a polymerizable compound B that contains a functional group.
Abstract:
The present invention aims to provide a surface modification method for a rubber vulcanizate or a thermoplastic elastomer, which can impart excellent sliding properties and durability against repeated sliding motion and can allow the surface to maintain the sealing properties, without using expensive self-lubricating plastics. The present invention relates to a surface modification method for modifying a rubber vulcanizate or a thermoplastic elastomer as an object to be modified, the method including: Step 1 of allowing a photopolymerization initiator to be adsorbed on a surface of the object to be modified; and Step 2 of radical polymerizing monomers, starting from the adsorbed photopolymerization initiator, by irradiation with UV light at a wavelength of 300 nm to 400 nm to grow polymer chains on the surface of the object to be modified.
Abstract:
Provided is a polymer-coated glass substrate having a surface with controlled irregularity and a low elastic modulus. The polymer-coated glass substrate includes a glass substrate and two or more hydrophilic polymer layers on a surface of the glass substrate.
Abstract:
Provided are hydrophilic substrates provided with a hydrophilic polymer layer having controlled surface uniformity and irregularities, and methods for preparing the hydrophilic substrates. Included are hydrophilic substrates including a substrate having a surface containing at least one group represented by —N(R1)2 or —N(R2)3+ wherein each R1 or R2 is the same or different and represents a hydrogen atom or a substituted or unsubstituted hydrocarbon group optionally containing a hetero atom; and a hydrophilic polymer layer provided on the surface of the substrate.
Abstract:
Provided is a method of producing a polymer-impregnated base resin which is excellent in providing low adsorption of proteins and blood cells such as platelets. The method of producing a polymer-impregnated base resin includes impregnating a base resin with a polymer solution that includes a solvent able to swell the base resin.
Abstract:
The present invention provides a gasket excellent in properties such as sliding properties and resistance to liquid leakage. The present invention relates to a gasket including a gasket base material whose surface is at least partially provided with immobilized polymer chains, the gasket having a sliding surface provided with multiple annular projections, the annular projections including a first projection nearest to the top surface of the gasket, the first projection having a surface roughness Ra of 1.0 or less.