METHODS AND COMPOSITIONS FOR DELIVERY OF EXOGENOUS FACTORS TO NERVIOUS SYSTEM SITES
    2.
    发明申请
    METHODS AND COMPOSITIONS FOR DELIVERY OF EXOGENOUS FACTORS TO NERVIOUS SYSTEM SITES 审中-公开
    用于将外源因子递送到神经系统网站的方法和组合

    公开(公告)号:US20110217264A1

    公开(公告)日:2011-09-08

    申请号:US13108552

    申请日:2011-05-16

    摘要: The present invention relates to treatment methods and methods for sustained delivery of one or more exogenous factors to desired nervous system sites. In certain embodiments, the invention relates to the use of biodegradable microspheres to deliver exogenous factors, such as the morphogenic factor, sonic hedgehog (Shh), to the site of spinal cord injury. In certain embodiments, the Shh-releasing microspheres are administered together with stem cells, which may be spinal cord neural stem cells. In certain embodiments, the invention relates to regrowth of neural cells in both the central and peripheral nervous systems.

    摘要翻译: 本发明涉及用于将一种或多种外源因子持续递送至所需神经系统部位的治疗方法和方法。 在某些实施方案中,本发明涉及生物可降解微球体将外源性因子(例如形态发生因子,声波刺猬(Shh))递送至脊髓损伤部位的用途。 在某些实施方案中,将释放Shh的微球与干细胞一起施用,所述干细胞可以是脊髓神经干细胞。 在某些实施方案中,本发明涉及神经细胞在中枢神经系统和外周神经系统中的再生长。

    RETINAL PIGMENT EPITHELIAL STEM CELLS
    4.
    发明申请
    RETINAL PIGMENT EPITHELIAL STEM CELLS 有权
    RETINAL PIGMENT上皮干细胞

    公开(公告)号:US20090274667A1

    公开(公告)日:2009-11-05

    申请号:US12428456

    申请日:2009-04-22

    摘要: The present invention relates to a retinal pigment epithelial stem cell isolated from a posterior region of the retinal pigment epithelium of an adult mammal. The invention also relates to a method of inducing differentiation of retinal epithelial stem and progenitor cells in vitro, wherein the cells of the invention are highly plastic, multipotential stem cells. The invention also includes methods for the treatment of retinal diseases and vision loss involving the transplantation of retinal pigment epithelial stem cells or cells differentiated from retinal pigment epithelial stem cells to the retina of a patient in need of treatment.

    摘要翻译: 本发明涉及从成年哺乳动物的视网膜色素上皮的后部区域分离的视网膜色素上皮干细胞。 本发明还涉及在体外诱导视网膜上皮干细胞和祖细胞分化的方法,其中本发明的细胞是高度塑性的,多能干细胞。 本发明还包括治疗视网膜疾病和视力丧失的方法,涉及将视网膜色素上皮干细胞或从视网膜色素上皮干细胞分化的细胞移植到需要治疗的患者的视网膜中。

    User-directed navigation of multimedia search results
    7.
    发明申请
    User-directed navigation of multimedia search results 审中-公开
    多媒体搜索结果的用户导向导航

    公开(公告)号:US20070106646A1

    公开(公告)日:2007-05-10

    申请号:US11395732

    申请日:2006-03-31

    IPC分类号: G06F17/30

    CPC分类号: G06F16/739 G06F16/7844

    摘要: According to one aspect, a computerized method and apparatus for generating and presenting search snippets that enable user-directed navigation of the underlying audio/video content. The method involves obtaining metadata associated with discrete media content that satisfies a search query. The metadata identifies a number of content segments and corresponding timing information derived from the underlying media content using one or more automated media processing techniques. Using the timing information identified in the metadata, a search result or “snippet” can be generated that enables a user to arbitrarily select and commence playback of the underlying media content at any of the individual content segments.

    摘要翻译: 根据一个方面,一种用于生成和呈现搜索片段的计算机化方法和装置,其使得能够进行底层音频/视频内容的用户导向的导航。 该方法涉及获得与满足搜索查询的离散媒体内容相关联的元数据。 元数据使用一个或多个自动化媒体处理技术来识别从底层媒体内容导出的多个内容片段和相应的定时信息。 使用在元数据中标识的定时信息,可以生成搜索结果或“片段”,其使得用户能够任意选择并开始任何单个内容片段下的底层媒体内容的播放。

    Method and apparatus for using confidence scores of enhanced metadata in search-driven media applications
    8.
    发明申请
    Method and apparatus for using confidence scores of enhanced metadata in search-driven media applications 审中-公开
    在搜索驱动媒体应用中使用增强元数据的置信度分数的方法和装置

    公开(公告)号:US20070106660A1

    公开(公告)日:2007-05-10

    申请号:US11444826

    申请日:2006-06-01

    IPC分类号: G06F17/30

    CPC分类号: G06F16/739 G06F16/7844

    摘要: According to one aspect, a computerized method and apparatus for generating and presenting search snippets that enable user-directed navigation of the underlying audio/video content. The method involves obtaining metadata associated with discrete media content that satisfies a search query. The metadata identifies a number of content segments and corresponding timing information derived from the underlying media content using one or more automated media processing techniques. Using the timing information identified in the metadata, a search result or “snippet” can be generated that enables a user to arbitrarily select and commence playback of the underlying media content at any of the individual content segments.

    摘要翻译: 根据一个方面,一种用于生成和呈现搜索片段的计算机化方法和装置,其使得能够进行底层音频/视频内容的用户导向的导航。 该方法涉及获得与满足搜索查询的离散媒体内容相关联的元数据。 元数据使用一个或多个自动化媒体处理技术来识别从底层媒体内容导出的多个内容片段和相应的定时信息。 使用在元数据中标识的定时信息,可以生成搜索结果或“片段”,其使得用户能够任意选择并开始任何单个内容片段下的底层媒体内容的播放。

    Methods and apparatus for merging media content
    10.
    发明申请
    Methods and apparatus for merging media content 审中-公开
    合并媒体内容的方法和设备

    公开(公告)号:US20070118873A1

    公开(公告)日:2007-05-24

    申请号:US11446543

    申请日:2006-06-02

    摘要: A computerized method and apparatus is disclosed for merging content segments from a number of discrete media content (e.g., audio/video podcasts) in preparation for playback. The method and apparatus obtain metadata corresponding to a plurality of discrete media content. The metadata identifies the content segments and their corresponding timing information, such that the metadata of at least one of the plurality of discrete media content is derived using one or more media processing techniques. A number of the content segments are selected to be merged for playback using the timing information from the metadata. The merged media content can be implemented as a playlist identifying the content segments to be merged for playback. The merged media content can also be generated by extracting the content segments to be merged for playback from each of the media files/streams and then merging the extracted segments into one or more merged media files/streams.

    摘要翻译: 公开了一种计算机化的方法和装置,用于从准备播放的多个离散媒体内容(例如,音频/视频播客)中合并内容片段。 所述方法和装置获得对应于多个离散媒体内容的元数据。 元数据识别内容片段及其对应的定时信息,使得使用一种或多种媒体处理技术导出多个离散媒体内容中的至少一个的元数据。 使用来自元数据的定时信息来选择多个内容段被合并以进行回放。 合并的媒体内容可以被实现为标识要合并用于回放的内容片段的播放列表。 也可以通过从每个媒体文件/流中提取要被合并以进行再现的内容片段,然后将提取的片段合并到一个或多个合并的媒体文件/流中来生成合并的媒体内容。