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公开(公告)号：US09108198B2
公开(公告)日：2015-08-18
申请号：US14052464
申请日：2013-10-11
Applicant: Samsung Electronics Co., Ltd.
Inventor： Minseok S. Kim , Hui-sung Moon , Jong-myeon Park
CPC classification number: B01L3/502753 , B01L2300/0803 , B01L2300/0858 , B01L2300/0864 , B01L2300/0874 , B01L2400/0409 , B01L2400/0677 , B01L2400/086 , G01N21/07
Abstract: Provided is a microfluidic apparatus that is mounted on a rotation driver and induces a flow of a fluid due to a centrifugal force, the microfluidic apparatus including: a separation unit that separates a target cell from a sample; a recovery chamber that is connected to the separation unit through a recovery channel and accommodates the target cell obtained by the separation; and an inclined portion that is disposed in the recovery chamber and tilted toward a bottom of the recovery chamber along a direction of the centrifugal force.
Abstract translation: 提供了一种微流体装置，其安装在旋转驱动器上并且由于离心力而引起流体流动，所述微流体装置包括：分离单元，其将目标细胞与样品分离; 回收室，其通过回收通道连接到分离单元，并容纳通过分离获得的靶单元; 以及倾斜部，其设置在所述回收室中并沿着所述离心力的方向朝向所述回收室的底部倾斜。
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2.发明授权公开(公告)号：US09557316B2
公开(公告)日：2017-01-31
申请号：US14261708
申请日：2014-04-25
Applicant: Samsung Electronics Co., Ltd.
Inventor： Minseok S. Kim , Hui-sung Moon , Jong-myeon Park
CPC classification number: G01N33/491 , B01L3/502715 , B01L3/50273 , B01L3/502738 , B01L3/502753 , B01L2200/0652 , B01L2200/10 , B01L2200/14 , B01L2300/0803 , B01L2300/0864 , B01L2300/1861 , B01L2400/0409 , B01L2400/0677 , F16K99/0001 , F16K2099/0084 , Y10T436/25375
Abstract: Disclosed are sample analysis apparatus and methods. A sample analysis apparatus includes a first unit that rotates a microfluidic apparatus including: a chamber having a space accommodating a sample, a channel that provides a path through which the sample flows; and a valve that selectively opens and closes the channel, a valve driver that supplies energy, used to operate the valve, to the valve in a state of being separated from the microfluidic apparatus, a third unit that rotates the valve driver with respect to a common rotation axis with a rotation axis of the microfluidic apparatus and the third unit, and a control unit that controls the first and third units and the valve driver to supply energy to the valve while the microfluidic apparatus and the valve driver are being rotated at the same rotation speed.
Abstract translation: 公开的是样品分析装置和方法。 样品分析装置包括旋转微流体装置的第一单元，包括：具有容纳样品的空间的腔室，提供样品流过的路径的通道; 以及选择性地打开和关闭所述通道的阀，在与所述微流体装置分离的状态下向所述阀提供用于操作所述阀的能量的阀驱动器，使所述阀驱动器相对于所述阀驱动器旋转的第三单元 具有微流体装置和第三单元的旋转轴的共同旋转轴，以及控制单元，其控制第一和第三单元和阀驱动器在微流体装置和阀驱动器正在旋转时向阀提供能量 相同的转速。
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Patent Agency Ranking
3.发明申请COMPOSITION AND KIT FOR SEPARATING CANCER CELL, AND METHOD OF SEPARATING CANCER CELL BY USING THE COMPOSITION AND KIT 审中-公开用于分离癌细胞的组合物和试剂盒，以及使用组合物和试剂盒分离癌细胞的方法公开(公告)号：US20150064721A1
公开(公告)日：2015-03-05
申请号：US14252284
申请日：2014-04-14
Inventor： Yeon-jeong KIM , Kyung-yeon Han , You-Sun Kim , Hui-sung Moon , Dong-hyun Park , Jong-myeon Park
IPC: G01N33/574 , C07K16/30 , C07K16/40
CPC classification number: G01N33/57492 , C07K16/2851 , C07K16/30 , G01N33/57415 , G01N33/57423 , G01N33/57434 , G01N2333/70596
Abstract: Provided is a composition and a kit for separating a cancer stem cell or a circulating tumor cell, a method of separating a cancer stem cell or a circulating tumor cell in a biological sample, and a method for diagnosing metastatic cancer.
Abstract translation: 提供了用于分离癌症干细胞或循环肿瘤细胞的组合物和试剂盒，分离生物样品中的癌症干细胞或循环肿瘤细胞的方法，以及诊断转移性癌症的方法。
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4.发明授权Microfluidic apparatus with increased recovery rate of target material from a sample 有权微流控装置，从样品中提取目标物质的回收率公开(公告)号：US09421541B2
公开(公告)日：2016-08-23
申请号：US14144165
申请日：2013-12-30
Applicant: Samsung Electronics Co., Ltd.
Inventor： Hui-sung Moon , Min-Seok S. Kim , Jong-myeon Park
CPC classification number: B01L3/502715 , B01L2200/027 , B01L2300/041 , B01L2300/0803 , B01L2300/0887 , B01L2400/0409 , B01L2400/0677 , B01L2400/0683 , B04B5/0407 , B04B7/02 , B04B11/00 , G01N1/4077 , G01N2035/00495
Abstract: A microfluidic apparatus that is mounted on a rotation driver and induces a flow of a fluid according to a centrifugal force includes a lower structure having a microfluidic structure including a recovery chamber for accommodating a target material separated from a sample and a channel for forming an inflow path of the target material to the recovery chamber; an upper plate forming an upper wall of the recovery chamber and the channel; and a lid formed integrally to the upper plate and removable from the upper plate to open at least a part of a top of the recovery chamber.
Abstract translation: 安装在旋转驱动器上并根据离心力引起流体流动的微流体装置包括具有微流体结构的下部结构，该微结构结构包括用于容纳从样品分离的靶材料的回收室和用于形成流入物 目标材料到回收室的路径; 形成所述回收室的上壁和所述通道的上板; 以及与所述上板一体地形成并且可从所述上板移除以打开所述回收室的顶部的至少一部分的盖。
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5.发明申请公开(公告)号：US20150104814A1
公开(公告)日：2015-04-16
申请号：US14261708
申请日：2014-04-25
Applicant: Samsung Electronics Co., Ltd.
Inventor： Minseok S. KIM , Hui-sung Moon , Jong-myeon Park
IPC: B01L3/00 , G01N33/49 , G01N33/574
CPC classification number: G01N33/491 , B01L3/502715 , B01L3/50273 , B01L3/502738 , B01L3/502753 , B01L2200/0652 , B01L2200/10 , B01L2200/14 , B01L2300/0803 , B01L2300/0864 , B01L2300/1861 , B01L2400/0409 , B01L2400/0677 , F16K99/0001 , F16K2099/0084 , Y10T436/25375
Abstract: Disclosed are sample analysis apparatus and methods. A sample analysis apparatus includes a first unit that rotates a microfluidic apparatus including: a chamber having a space accommodating a sample, a channel that provides a path through which the sample flows; and a valve that selectively opens and closes the channel, a valve driver that supplies energy, used to operate the valve, to the valve in a state of being separated from the microfluidic apparatus, a third unit that rotates the valve driver with respect to a common rotation axis with a rotation axis of the microfluidic apparatus and the third unit, and a control unit that controls the first and third units and the valve driver to supply energy to the valve while the microfluidic apparatus and the valve driver are being rotated at the same rotation speed.
Abstract translation: 公开的是样品分析装置和方法。 样品分析装置包括旋转微流体装置的第一单元，包括：具有容纳样品的空间的腔室，提供样品流过的路径的通道; 以及选择性地打开和关闭所述通道的阀，在与所述微流体装置分离的状态下向所述阀提供用于操作所述阀的能量的阀驱动器，使所述阀驱动器相对于所述阀驱动器旋转的第三单元 具有微流体装置和第三单元的旋转轴的共同旋转轴，以及控制单元，其控制第一和第三单元和阀驱动器在微流体装置和阀驱动器正在旋转时向阀提供能量 相同的转速。
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公开(公告)号：US09737889B2
公开(公告)日：2017-08-22
申请号：US14273697
申请日：2014-05-09
Applicant: Samsung Electronics Co., Ltd.
Inventor： Hui-sung Moon , Min-Seok S. Kim , Jong-myeon Park
CPC classification number: B01L3/502738 , B01L3/50273 , B01L2200/0621 , B01L2300/0803 , B01L2300/0864 , B01L2300/087 , B01L2400/0409 , B01L2400/0677
Abstract: A microfluidic apparatus mounted on a rotation driving unit for inducing a fluid to flow due to a centrifugal force includes: a target chamber that houses a first fluid; a first chamber that houses a second fluid and is disposed closer to a rotation center of the microfluidic apparatus in a radius direction than the target chamber, the first chamber being connected to the target chamber by a first channel; a first valve that prevents a flow of the second fluid through the first channel; and a second chamber disposed closer to the rotation center in the radius direction than the target chamber and connected to the target chamber by a second channel, wherein the first fluid is transported to the second chamber by supplying the second fluid to the target chamber by the centrifugal force.
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公开(公告)号：US20140341788A1
公开(公告)日：2014-11-20
申请号：US14052464
申请日：2013-10-11
Applicant: Samsung Electronics Co., Ltd.
Inventor： Minseok S. KIM , Hui-sung Moon , Jong-myeon Park
IPC: B01L3/00
CPC classification number: B01L3/502753 , B01L2300/0803 , B01L2300/0858 , B01L2300/0864 , B01L2300/0874 , B01L2400/0409 , B01L2400/0677 , B01L2400/086 , G01N21/07
Abstract: Provided is a microfluidic apparatus that is mounted on a rotation driver and induces a flow of a fluid due to a centrifugal force, the microfluidic apparatus including: a separation unit that separates a target cell from a sample; a recovery chamber that is connected to the separation unit through a recovery channel and accommodates the target cell obtained by the separation; and an inclined portion that is disposed in the recovery chamber and tilted toward a bottom of the recovery chamber along a direction of the centrifugal force.
Abstract translation: 提供了一种微流体装置，其安装在旋转驱动器上并且由于离心力而引起流体流动，所述微流体装置包括：分离单元，其将目标细胞与样品分离; 回收室，其通过回收通道连接到分离单元，并容纳通过分离获得的靶单元; 以及倾斜部，其设置在所述回收室中并沿着所述离心力的方向朝向所述回收室的底部倾斜。
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