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公开(公告)号:US20240324447A1
公开(公告)日:2024-09-26
申请号:US18609445
申请日:2024-03-19
发明人: Hwang Suk Kim , Youngmin You , Chung Thanh PHAM , Sreenivas AVULA , Joonghyuk Kim , Yongsik Jung , Hyeonho Choi
CPC分类号: H10K85/371 , C07F1/00 , C09K11/06 , C09K2211/1059 , C09K2211/188 , H10K50/121
摘要: An organometallic compound represented by Formula 1:
wherein X1 is N or C(R1), and X2 is N or C(R2); at least one of X1 and X2 is N; Y1 is a single bond, O, S, Se, N(R3), C(R3)(R4), Si(R3)(R4), Ge(R3)(R4), B(R3), P(R3), P(═O)(R3), S(═O)2, or C(═O); n1 is 0, 1, or 2; A1 and A2 are each independently a C5-C30 carbocyclic group or a C1-C30 heterocyclic group; wherein the remaining substituent groups are as defined herein.-
公开(公告)号:US11939308B2
公开(公告)日:2024-03-26
申请号:US17059754
申请日:2019-05-30
发明人: Kong Joo Lee , Hee-Yoon Lee , Je Jin Lee , Hwang Suk Kim , Ji-Wan Seo , Hongsoo Lee , Ji Soo Shin , Bo-kyung Kim
IPC分类号: C07D303/18 , A23L33/10 , A61P35/04 , C07C35/21 , C07C43/23 , C07C235/56
CPC分类号: C07D303/18 , A23L33/10 , A61P35/04 , C07C35/21 , C07C43/23 , C07C235/56
摘要: The present disclosure provides a novel biphenyl derivative compound or a pharmaceutically acceptable salt thereof. The biphenyl derivative compound or pharmaceutically acceptable salt thereof according to the present disclosure is a compound that increases Nm23-H1/NDPK activity and can inhibit cancer metastasis and growth. Thus, it exhibits excellent effects not only on the prevention, alleviation and treatment of cancer, but also on the suppression of cancer metastasis.
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公开(公告)号:US20210206706A1
公开(公告)日:2021-07-08
申请号:US17059762
申请日:2019-05-30
发明人: Kong Joo Lee , Hee-Yoon Lee , Je Jin Lee , Hongsoo Lee , Ji-wan Seo , Hwang Suk Kim , Bo-kyung Kim , Ji Soo Shin
IPC分类号: C07C43/23 , C07C49/175 , A61K31/337 , A61K31/12 , A61K31/09 , A61P35/00 , A61K9/00 , A23L33/00 , A23L33/10
摘要: The present disclosure provides a novel biphenyl derivative compound, an optical isomer thereof or a pharmaceutically acceptable salt thereof. The biphenyl derivative compound, optical isomer thereof or pharmaceutically acceptable salt thereof according to the present disclosure may induce cancer cell death by damaging mitochondria and inducing ATP depletion in cells which are in a nutrient-starved state such as a glucose-starved state, which is the normal environment of cancer cells. In addition, it is an Nm23-H1/NDPK activity-increasing substance that may suppress cancer metastasis and growth. Thus, it exhibits excellent effects not only on the prevention, alleviation and treatment of cancer, but also on the suppression of cancer metastasis.
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公开(公告)号:US12043594B2
公开(公告)日:2024-07-23
申请号:US17059762
申请日:2019-05-30
发明人: Kong Joo Lee , Hee-Yoon Lee , Je Jin Lee , Hongsoo Lee , Ji-wan Seo , Hwang Suk Kim , Bo-kyung Kim , Ji Soo Shin
IPC分类号: C07C43/23 , A23L33/00 , A23L33/10 , A61K9/00 , A61K31/09 , A61K31/12 , A61K31/337 , A61P35/00 , C07C49/175
CPC分类号: C07C43/23 , A23L33/10 , A23L33/40 , A61K9/0056 , A61K31/09 , A61K31/12 , A61K31/337 , A61P35/00 , C07C49/175 , A23V2002/00
摘要: The present disclosure provides a novel biphenyl derivative compound, an optical isomer thereof or a pharmaceutically acceptable salt thereof. The biphenyl derivative compound, optical isomer thereof or pharmaceutically acceptable salt thereof according to the present disclosure may induce cancer cell death by damaging mitochondria and inducing ATP depletion in cells which are in a nutrient-starved state such as a glucose-starved state, which is the normal environment of cancer cells. In addition, it is an Nm23-H1/NDPK activity-increasing substance that may suppress cancer metastasis and growth. Thus, it exhibits excellent effects not only on the prevention, alleviation and treatment of cancer, but also on the suppression of cancer metastasis.
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公开(公告)号:US20210214324A1
公开(公告)日:2021-07-15
申请号:US17059754
申请日:2019-05-30
发明人: Kong Joo Lee , Hee-Yoon Lee , Je Jin Lee , Hwang Suk Kim , Ji-wan Seo , Hongsoo Lee , Ji Soo Shin , Bo-kyung Kim
IPC分类号: C07D303/18 , C07C35/21 , C07C43/23 , C07C235/56 , A23L33/10 , A61P35/04
摘要: The present disclosure provides a novel biphenyl derivative compound or a pharmaceutically acceptable salt thereof. The biphenyl derivative compound or pharmaceutically acceptable salt thereof according to the present disclosure is a compound that increases Nm23-H1/NDPK activity and can inhibit cancer metastasis and growth. Thus, it exhibits excellent effects not only on the prevention, alleviation and treatment of cancer, but also on the suppression of cancer metastasis.
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公开(公告)号:US11849595B2
公开(公告)日:2023-12-19
申请号:US16944873
申请日:2020-07-31
发明人: Hwang Suk Kim , Ohkyu Kwon , Bum Woo Park , Kwang Hee Lee , Dong-Seok Leem , Hyesung Choi , Dongseon Lee
IPC分类号: C07D285/14 , C07D293/10 , H10K30/20 , H10K30/87 , H10K85/10
CPC分类号: H10K30/20 , C07D285/14 , C07D293/10 , H10K30/87 , H10K85/111
摘要: A near-infrared absorber includes a compound represented by Chemical Formula 1. A near-infrared absorbing/blocking film, a photoelectric device, an organic sensor, and an electronic device may include the near-infrared absorber.
In Chemical Formula 1, Ar1, Ar2, X1, L1, L2, R1, R2, R3, and R4 are the same as defined in the detailed description.-
公开(公告)号:US11158676B2
公开(公告)日:2021-10-26
申请号:US16788857
申请日:2020-02-12
发明人: Dong-Seok Leem , Rae Sung Kim , Hyesung Choi , Ohkyu Kwon , Changki Kim , Hwang Suk Kim , Bum Woo Park , Jae Jun Lee
IPC分类号: H01L27/30 , H01L27/146 , H01L51/42 , H01L51/50
摘要: A sensor includes an anode and a cathode, and a near-infrared photoelectric conversion layer between the anode and the cathode. The near-infrared photoelectric conversion layer is configured to absorb light of at least a portion of a near-infrared wavelength spectrum and convert the absorbed light into an electrical signal. The near-infrared photoelectric conversion layer includes a first material having a maximum absorption wavelength in the near-infrared wavelength spectrum and a second material forming a pn junction with the first material and having a wider energy bandgap than an energy bandgap of the first material. The first material is included in the near-infrared photoelectric conversion layer in a smaller amount than the second material.
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公开(公告)号:US20200296269A1
公开(公告)日:2020-09-17
申请号:US16536583
申请日:2019-08-09
发明人: Dong-Seok LEEM , Gae Hwang Lee , Ohkyu Kwon , Kwang Hee Lee , Hwang Suk Kim , Bum Woo Park , Hyesung Choi
摘要: A sensor includes a visible light sensor configured to sense light in a visible wavelength spectrum, a near infra-red light sensor on the visible light sensor and configured to sense light in a near infra-red wavelength spectrum, and an optical filter on the near infra-red light sensor and configured to selectively transmit the light in the visible wavelength spectrum and the light in the near infra-red wavelength spectrum, and an electronic device.
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公开(公告)号:US11849597B2
公开(公告)日:2023-12-19
申请号:US17485737
申请日:2021-09-27
发明人: Dong-Seok Leem , Rae Sung Kim , Hyesung Choi , Ohkyu Kwon , Changki Kim , Hwang Suk Kim , Bum Woo Park , Jae Jun Lee
IPC分类号: H01L27/146 , H10K39/32 , H10K30/20 , H10K30/30 , H10K50/11 , H10K101/40
CPC分类号: H10K39/32 , H01L27/14669 , H10K30/20 , H10K30/30 , H10K50/11 , H10K2101/40
摘要: A sensor includes an anode and a cathode, and a near-infrared photoelectric conversion layer between the anode and the cathode. The near-infrared photoelectric conversion layer is configured to absorb light of at least a portion of a near-infrared wavelength spectrum and convert the absorbed light into an electrical signal. The near-infrared photoelectric conversion layer includes a first material having a maximum absorption wavelength in the near-infrared wavelength spectrum and a second material forming a pn junction with the first material and having a wider energy bandgap than an energy bandgap of the first material. The first material is included in the near-infrared photoelectric conversion layer in a smaller amount than the second material.
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公开(公告)号:US20230357150A1
公开(公告)日:2023-11-09
申请号:US18312051
申请日:2023-05-04
发明人: Yeon Sook Chung , Eunjeong Choi , Eunhye AN , Heechoon Ahn , Giwook Kang , Eunsuk Kwon , Yeseul Lee , Dongjin Jang , Seowon Cho , Yongsik Jung , Hwang Suk Kim , Hyeonho Choi , Byoungki Choi
IPC分类号: C07D209/84 , H10K50/12 , H10K50/15 , H10K50/16 , H10K85/60
CPC分类号: C07D209/84 , H10K50/12 , H10K50/15 , H10K50/16 , H10K85/6572
摘要: Provided are a heterocyclic compound represented by Formula 1A, an organic light-emitting device including the same, and an electronic apparatus including the organic light-emitting device:
wherein a detailed description of Formula 1A is provided in the specification.
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