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公开(公告)号：US08402967B2
公开(公告)日：2013-03-26
申请号：US13216529
申请日：2011-08-24
申请人： Michael S. Smith , Greg Voss , Peter Bliss , Scott Halperin
发明人： Michael S. Smith , Greg Voss , Peter Bliss , Scott Halperin
IPC分类号： A61M15/00
CPC分类号： A61M16/12 , A61M16/08 , A61M16/107 , A61M16/204 , A61M16/209 , A61M2016/0027 , A61M2016/003 , A61M2202/0208 , A61M2205/70
摘要： A gas blender with auxiliary mixed gas outlet for mixing a primary gas, generally air, and a secondary gas, generally oxygen, to obtain a mixed gas having several controlled characteristics. The gas blender may be incorporated into a Continuous Positive Airway Pressure (CPAP) device. The gas blender controls the mixing to produce the mixed gas having a predetermined mixture setpoint, generally an oxygen percentage, and a predetermined control setpoint, generally a pressure setpoint or flow rate setpoint. The gas blender provides an auxiliary mixed gas source for use by an auxiliary piece of equipment such as a nebulizer or resuscitation bag. The gas blender includes a primary gas inlet passageway, a secondary gas inlet passageway, a gas mixing apparatus, a mixed gas distribution passageway with an auxiliary mixed gas outlet, a gas sensor, a delivery sensor, a mixed gas delivery control valve, a mixed gas controlled passageway, and a controller.
摘要翻译： 一种具有辅助混合气体出口的气体混合器，用于混合初级气体（通常为空气）和二次气体（通常为氧气），以获得具有几个受控特性的混合气体。 气体混合器可以并入连续气道正压通气（CPAP）装置中。 气体混合器控制混合以产生具有预定混合物设定点（通常为氧气百分比）和预定控制设定点（通常为压力设定点或流量设定点）的混合气体。 气体混合器提供辅助混合气体源，用于辅助设备如雾化器或复苏袋。 气体混合器包括主气体入口通道，二次气体入口通道，气体混合设备，具有辅助混合气体出口的混合气体分配通道，气体传感器，输送传感器，混合气体输送控制阀，混合 气体控制通道和控制器。
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公开(公告)号：US07614420B2
公开(公告)日：2009-11-10
申请号：US11405341
申请日：2006-04-17
申请人： Andre Rustad , Scott Halperin
发明人： Andre Rustad , Scott Halperin
IPC分类号： F16K31/18
CPC分类号： A61M16/167 , A61M16/1075 , A61M16/168 , F16K31/20 , F24F6/02 , Y10T137/0318 , Y10T137/6579 , Y10T137/7404 , Y10T137/742 , Y10T137/7426
摘要： An autofeed mechanism for controlling the flow and level of a fluid. The mechanism includes a body with an inlet chamber and a float chamber. A seat permits fluid communication between the two chambers. A float and a ball cooperate to permit, or deny, access to the seat. Fluid first enters the inlet and fills the chamber and then enters the float chamber by passing through the seat and exiting via the exit. Initially, the weight of the float keeps the ball away from the seat, but eventually the fluid level rises high enough that the action of the float on the ball decreases to a level that is overcome by the buoyant force of the ball and other fluidic forces resulting in the ball moving away from the ball support. Finally, the ball rises enough to seal against the seat thus stopping the flow of fluid.
摘要翻译： 用于控制流体的流量和水平的自动进给机构。 该机构包括具有入口室和浮子室的主体。 一个座位允许两个腔室之间的流体连通。 一个浮球和一个球合作允许或拒绝进入座位。 流体首先进入入口并填充室，然后通过穿过座并通过出口离开进入浮子室。 最初，浮子的重量使球远离座椅，但是最终液面上升到足够高的程度，使得球上的浮球的作用降低到由球的浮力和其他流体力所克服的水平 导致球离开球支撑。 最后，球上升到足以密封座位，从而阻止流体的流动。
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公开(公告)号：US20070227360A1
公开(公告)日：2007-10-04
申请号：US11731346
申请日：2007-03-30
申请人： Charles Atlas , Peter Bliss , Robert Murdoch , Scott Halperin
发明人： Charles Atlas , Peter Bliss , Robert Murdoch , Scott Halperin
IPC分类号： B01D53/02
CPC分类号： B01D53/047 , A61M16/10 , A61M16/101 , A61M16/107 , A61M2016/0021 , A61M2016/0027 , A61M2016/1025 , A61M2202/0208 , A61M2202/03 , A61M2205/505 , B01D53/0407 , B01D53/0446 , B01D53/0454 , B01D2253/108 , B01D2256/12 , B01D2257/102 , B01D2259/402 , B01D2259/406 , B01D2259/4146 , B01D2259/4533 , B01D2259/4541 , C01B13/0259 , C01B2210/0046 , C01B2210/0062 , G06F3/0488 , A61M2202/0007
摘要： A portable oxygen concentrator includes a pressure swing absorption system defined by a relatively rigid housing adapted to generate a flow of oxygen enriched gas and a battery adapted to provide power to the pressure swing absorption system. The oxygen concentrator has a total weight of less than about 10 lbs, has a maximum flow of 100% O2 equivalent gas of about 0.9 lpm, has a total volume less than about 800 in3, and gas a battery life of at least about 8 hours. The present invention also using a liquefaction or transfill system in combination with such an oxygen concentrator.
摘要翻译： 便携式氧气浓缩器包括由适于产生富氧气体流的相对刚性的壳体限定的压力摆动吸收系统和适于向变压吸收系统提供动力的电池。 氧浓缩器的总重量小于约10磅，具有约0.9lpm的100％O 2当量气体的最大流量，其总体积小于约3×10 3 ，并将电池寿命延长至少约8小时。 本发明还使用与这种氧气浓缩器组合的液化或输送系统。
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公开(公告)号：US20070125374A1
公开(公告)日：2007-06-07
申请号：US11292641
申请日：2005-12-02
申请人： Michael Smith , Greg Voss , Peter Bliss , Scott Halperin
发明人： Michael Smith , Greg Voss , Peter Bliss , Scott Halperin
CPC分类号： A61M16/12 , A61M16/08 , A61M16/107 , A61M16/204 , A61M16/209 , A61M2016/0027 , A61M2016/003 , A61M2202/0208 , A61M2205/70
摘要： A gas blender with auxiliary mixed gas outlet for mixing a primary gas, generally air, and a secondary gas, generally oxygen, to obtain a mixed gas having several controlled characteristics. The gas blender may be incorporated into a Continuous Positive Airway Pressure (CPAP) device. The gas blender controls the mixing to produce the mixed gas having a predetermined mixture setpoint, generally an oxygen percentage, and a predetermined control setpoint, generally a pressure setpoint or flow rate setpoint. The gas blender provides an auxiliary mixed gas source for use by an auxiliary piece of equipment such as a nebulizer or resuscitation bag. The gas blender includes a primary gas inlet passageway, a secondary gas inlet passageway, a gas mixing apparatus, a mixed gas distribution passageway with an auxiliary mixed gas outlet, a gas sensor, a delivery sensor, a mixed gas delivery control valve, a mixed gas controlled passageway, and a controller.
摘要翻译： 一种具有辅助混合气体出口的气体混合器，用于混合初级气体（通常为空气）和二次气体（通常为氧气），以获得具有几个受控特性的混合气体。 气体混合器可以并入连续气道正压通气（CPAP）装置中。 气体混合器控制混合以产生具有预定混合物设定点（通常为氧气百分比）和预定控制设定点（通常为压力设定点或流量设定点）的混合气体。 气体混合器提供辅助混合气体源，用于辅助设备如雾化器或复苏袋。 气体混合器包括主气体入口通道，二次气体入口通道，气体混合设备，具有辅助混合气体出口的混合气体分配通道，气体传感器，输送传感器，混合气体输送控制阀，混合 气体控制通道和控制器。
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公开(公告)号：US06976488B2
公开(公告)日：2005-12-20
申请号：US10282418
申请日：2002-10-30
申请人： Scott Halperin
发明人： Scott Halperin
CPC分类号： A61M16/1045 , A61M16/0833
摘要： The present invention provides a heat and moisture exchange (HME) unit that includes a housing having a fibrous media in the housing that is designed to absorb and retain moisture and heat from exhaled air passing through the housing. The HME unit is designed to transfer the moisture and heat to inhaled air passing through the HME unit. The HME unit has an internal bypass in the housing to enable air to pass through the heat HME unit without passing through the fibrous media. The present invention also provides a breathing circuit that includes a medication bypass HME unit, a medication treatment device and a ventilator that is connected in a closed system.
摘要翻译： 本发明提供了一种热和湿气交换（HME）单元，其包括在壳体中具有纤维介质的壳体，其被设计成吸收并保持通过壳体的呼出空气的湿气和热量。 HME设备旨在将湿气和热量转移到通过HME单元的吸入空气中。 HME单元在壳体中具有内部旁路，以使空气能够通过热HME单元而不通过纤维介质。 本发明还提供了一种呼吸回路，其包括在闭合系统中连接的药物旁路HME单元，药物治疗装置和呼吸机。
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公开(公告)号：US09061001B2
公开(公告)日：2015-06-23
申请号：US12587955
申请日：2009-10-15
申请人： Sylvia van Drunen Littel-van den Hurk , Volker Gerdts , Andrew Potter , Lorne Babiuk , Robert Hancock , Scott Halperin , Jennifer Kovacs-Nolan , George Mutwiri , Song Lee , Mi-Na Kweon , Jason Kindrachuk , Melissa Elliott
发明人： Sylvia van Drunen Littel-van den Hurk , Volker Gerdts , Andrew Potter , Lorne Babiuk , Robert Hancock , Scott Halperin , Jennifer Kovacs-Nolan , George Mutwiri , Song Lee , Mi-Na Kweon , Jason Kindrachuk , Melissa Elliott
IPC分类号： A61K49/00 , A61K47/00 , A61K38/04 , A61K39/39 , A61K39/02 , A61K39/155 , C07K7/08 , A61K45/06 , A61K47/30 , A61K39/00
CPC分类号： A61K39/39 , A61K39/099 , A61K39/12 , A61K39/155 , A61K45/06 , A61K47/30 , A61K2039/55516 , A61K2039/55561 , A61K2039/6093 , C07K7/08 , C12N2760/18534
摘要： Methods and compositions for enhancing an immune response to a selected antigen are described. The methods are useful for the treatment and prevention of microbial infections, such as infections caused by bacteria, viruses, fungi and parasites. The methods and compositions include host defense peptides, polyphosphazenes and immunostimulatory sequences to enhance the immune response to a coadministered antigen.
摘要翻译： 描述了增强对所选抗原的免疫应答的方法和组合物。 该方法可用于治疗和预防微生物感染，例如由细菌，病毒，真菌和寄生虫引起的感染。 方法和组合物包括宿主防御肽，聚磷腈和免疫刺激序列，以增强对共同施用的抗原的免疫应答。
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公开(公告)号：US20070240767A1
公开(公告)日：2007-10-18
申请号：US11405341
申请日：2006-04-17
申请人： Andre Rustad , Scott Halperin
发明人： Andre Rustad , Scott Halperin
IPC分类号： F16K31/18
CPC分类号： A61M16/167 , A61M16/1075 , A61M16/168 , F16K31/20 , F24F6/02 , Y10T137/0318 , Y10T137/6579 , Y10T137/7404 , Y10T137/742 , Y10T137/7426
摘要： An autofeed mechanism for controlling the flow and level of a fluid. The mechanism includes a body with an inlet chamber and a float chamber. A seat permits fluid communication between the two chambers. A float and a ball cooperate to permit, or deny, access to the seat. Fluid first enters the inlet and fills the chamber and then enters the float chamber by passing through the seat and exiting via the exit. Initially, the weight of the float keeps the ball away from the seat, but eventually the fluid level rises high enough that the action of the float on the ball decreases to a level that is overcome by the buoyant force of the ball and other fluidic forces resulting in the ball moving away from the ball support. Finally, the ball rises enough to seal against the seat thus stopping the flow of fluid.
摘要翻译： 用于控制流体的流量和水平的自动进给机构。 该机构包括具有入口室和浮子室的主体。 一个座位允许两个腔室之间的流体连通。 一个浮球和一个球合作允许或拒绝进入座位。 流体首先进入入口并填充室，然后通过穿过座并通过出口离开进入浮子室。 最初，浮子的重量使球远离座椅，但是最终液面上升到足够高的程度，使得球上的浮球的作用降低到由球的浮力和其他流体力所克服的水平 导致球离开球支撑。 最后，球上升到足以密封座位，从而阻止流体的流动。
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公开(公告)号：US20060230931A1
公开(公告)日：2006-10-19
申请号：US11099783
申请日：2005-04-05
申请人： Peter Bliss , Charles Atlas , Scott Halperin
发明人： Peter Bliss , Charles Atlas , Scott Halperin
IPC分类号： B01D53/02
CPC分类号： B01D53/053 , B01D53/0407 , B01D53/0446 , B01D53/0454 , B01D2253/108 , B01D2256/12 , B01D2257/102 , B01D2259/402 , B01D2259/406 , B01D2259/4146 , B01D2259/4533 , B01D2259/455 , C01B13/0259 , C01B2210/0046 , C01B2210/0062
摘要： A portable oxygen concentrator includes a pair of sieve beds having first and second ends, a compressor for delivering air to the first ends of the sieve beds, a reservoir communicating with the second ends of the sieve beds, and an air manifold attached to the first ends of the sieve beds. The air manifold includes passages therein communicating with the compressor and the first ends of the sieve beds. A set of valves is coupled to the air manifold, and a controller is coupled to the valves for selectively opening and closing the valves to alternately charge and purge the sieve beds to deliver concentrated oxygen into the reservoir. An oxygen delivery manifold communicates with the second ends of the sieve beds for delivering oxygen from the reservoir to a user. Pressure sensors may be provided in the reservoir and/or delivery line for controlling operation of the controller.
摘要翻译： 便携式氧浓缩器包括一对具有第一和第二端的筛床，用于将空气输送到筛床的第一端的压缩机，与筛床的第二端连通的储存器，以及连接到第一端的空气歧管 筛床的两端。 空气歧管包括与压缩机和筛床的第一端连通的通道。 一组阀联接到空气歧管，并且控制器联接到阀，用于选择性地打开和关闭阀，以交替地填充和吹扫筛床以将浓缩的氧输送到储存器中。 氧气输送歧管与筛床的第二端连通，用于将氧气从储存器输送到使用者。 可以在储存器和/或输送管线中设置压力传感器，以控制控制器的操作。
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公开(公告)号：US20110303219A1
公开(公告)日：2011-12-15
申请号：US13216529
申请日：2011-08-24
申请人： Michael S. Smith , Greg Voss , Peter Bliss , Scott Halperin
发明人： Michael S. Smith , Greg Voss , Peter Bliss , Scott Halperin
CPC分类号： A61M16/12 , A61M16/08 , A61M16/107 , A61M16/204 , A61M16/209 , A61M2016/0027 , A61M2016/003 , A61M2202/0208 , A61M2205/70
摘要： A gas blender with auxiliary mixed gas outlet for mixing a primary gas, generally air, and a secondary gas, generally oxygen, to obtain a mixed gas having several controlled characteristics. The gas blender may be incorporated into a Continuous Positive Airway Pressure (CPAP) device. The gas blender controls the mixing to produce the mixed gas having a predetermined mixture setpoint, generally an oxygen percentage, and a predetermined control setpoint, generally a pressure setpoint or flow rate setpoint. The gas blender provides an auxiliary mixed gas source for use by an auxiliary piece of equipment such as a nebulizer or resuscitation bag. The gas blender includes a primary gas inlet passageway, a secondary gas inlet passageway, a gas mixing apparatus, a mixed gas distribution passageway with an auxiliary mixed gas outlet, a gas sensor, a delivery sensor, a mixed gas delivery control valve, a mixed gas controlled passageway, and a controller.
摘要翻译： 一种具有辅助混合气体出口的气体混合器，用于混合初级气体（通常为空气）和二次气体（通常为氧气），以获得具有几个受控特性的混合气体。 气体混合器可以并入连续气道正压通气（CPAP）装置中。 气体混合器控制混合以产生具有预定混合物设定点（通常为氧气百分比）和预定控制设定点（通常为压力设定点或流量设定点）的混合气体。 气体混合器提供辅助混合气体源，用于辅助设备如雾化器或复苏袋。 气体混合器包括主气体入口通道，二次气体入口通道，气体混合设备，具有辅助混合气体出口的混合气体分配通道，气体传感器，输送传感器，混合气体输送控制阀，混合 气体控制通道和控制器。
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公开(公告)号：US08033292B2
公开(公告)日：2011-10-11
申请号：US12607277
申请日：2009-10-28
申请人： Andre Rustad , Scott Halperin
发明人： Andre Rustad , Scott Halperin
IPC分类号： F16K31/28
CPC分类号： A61M16/167 , A61M16/1075 , A61M16/168 , F16K31/20 , F24F6/02 , Y10T137/0318 , Y10T137/6579 , Y10T137/7404 , Y10T137/742 , Y10T137/7426
摘要： A heated humidifier including an autofeed mechanism disposed within a humidifier chamber. The autofeed mechanism includes a housing, a float, a stem, and a sealing body. The housing defines an inlet, an outlet, a first chamber connected to the inlet, and a second chamber connected to the outlet and the first chamber by a channel. The float moves within the second chamber with the stem projecting therefrom and through the channel. The sealing body is within the first chamber and cooperates with the stem. In an open state, the sealing body is displaced from the channel to permit filling of the humidifier chamber. In a closed state, the sealing body seals the channel to prevent liquid flow to the outlet. A location of the sealing body relative to the channel is controlled by the float as a function of a humidifier chamber liquid level.
摘要翻译： 一种加热加湿器，包括设置在加湿器室内的自动进给机构。 自动进给机构包括壳体，浮子，杆和密封体。 壳体限定入口，出口，连接到入口的第一室，以及通过通道连接到出口和第一室的第二室。 浮子在第二室内移动，其中杆从其突出并通过通道。 密封体在第一室内并与阀杆配合。 在打开状态下，密封体从通道移出以允许加湿器室的填充。 在关闭状态下，密封体密封通道以防止液体流入出口。 密封体相对于通道的位置由浮子作为加湿器室液面的函数来控制。
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