公开(公告)号：US20100023130A1

公开(公告)日：2010-01-28

申请号：US12356230

申请日：2009-01-20

申请人： Sebastien Henry ,  William Graham Midgette ,  Sejdefa Dozic ,  Kent Iversen ,  Guoqiang Mao ,  John Randolph Miller

发明人： Sebastien Henry ,  William Graham Midgette ,  Sejdefa Dozic ,  Kent Iversen ,  Guoqiang Mao ,  John Randolph Miller

IPC分类号： A61F2/02 ,  B31B1/62 ,  B29C39/12

CPC分类号： A61L27/48 ,  A61L27/56 ,  Y10T156/10

摘要： The present invention provides composite implants for the replacement or augmentation of non-load bearing or load bearing soft tissues, and methods of making and using these implant compositions. In one embodiment, a composite implant of the present invention comprises a soft polymeric component coupled to a porous polymeric substrate

摘要翻译： 本发明提供了用于替代或增加非承重或承载软组织的复合植入物，以及制造和使用这些植入物组合物的方法。 在一个实施方案中，本发明的复合植入物包含耦合到多孔聚合物基底的软聚合物组分

公开(公告)号：US08206450B2

公开(公告)日：2012-06-26

申请号：US12356230

申请日：2009-01-20

申请人： Sebastien Henry ,  William Graham Midgette ,  Sejdefa Dozic ,  Kent Iversen ,  Guoqiang Mao ,  John Randolph Miller

发明人： Sebastien Henry ,  William Graham Midgette ,  Sejdefa Dozic ,  Kent Iversen ,  Guoqiang Mao ,  John Randolph Miller

IPC分类号： A61F2/02

CPC分类号： A61L27/48 ,  A61L27/56 ,  Y10T156/10

摘要： The present invention provides composite implants for the replacement or augmentation of non-load bearing or load bearing soft tissues, and methods of making and using these implant compositions. In one embodiment, a composite implant of the present invention comprises a soft polymeric component coupled to a porous polymeric substrate.

摘要翻译： 本发明提供了用于替代或增加非承重或承载软组织的复合植入物，以及制造和使用这些植入物组合物的方法。 在一个实施方案中，本发明的复合植入物包含耦合到多孔聚合物基底的软聚合物组分。

公开(公告)号：US20200085548A1

公开(公告)日：2020-03-19

申请号：US16494504

申请日：2018-03-14

申请人： Delphine Reynard ,  Sabrina Capron-Richard ,  Sebastien Henry ,  Shoupu Chen ,  Aude Lagardere ,  Jean-Pascal Jacob ,  Carestream Dental Technology Topco Limited

发明人： Delphine Reynard ,  Sabrina Capron-Richard ,  Sebastien Henry ,  Shoupu Chen ,  Aude Lagardere ,  Jean-Pascal Jacob

IPC分类号： A61C13/34 ,  A61C9/00 ,  A61B6/14 ,  A61B6/03 ,  A61B6/00 ,  G06T19/20 ,  G06T17/20 ,  G06T7/00 ,  G06T7/62 ,  G06T7/149

摘要： A method for visualizing patient dentition acquires a contour image of patient dentition and segments the contour image to identify one or more segmented teeth. At least one deciduous tooth among the one or more segmented teeth is identified. A virtual model of a target dentition arrangement of the patient dentition is generated, wherein the at least one deciduous tooth is replaced by a replacement permanent tooth.

公开(公告)号：US09108882B2

公开(公告)日：2015-08-18

申请号：US12918518

申请日：2009-02-25

申请人： Eric Gouardes ,  Sebastien Henry ,  Sylvain Belliot

发明人： Eric Gouardes ,  Sebastien Henry ,  Sylvain Belliot

IPC分类号： B32B17/06 ,  C03C17/40 ,  C03C17/34 ,  C03C17/22 ,  C03C17/36

CPC分类号： C03C17/40 ,  C03C17/225 ,  C03C17/34 ,  C03C17/36 ,  C03C17/3615 ,  C03C17/3618 ,  C03C17/3626 ,  C03C17/3649 ,  C03C17/3652 ,  C03C17/366 ,  C03C17/3681 ,  Y10T428/2495 ,  Y10T428/24967 ,  Y10T428/315

摘要： The invention relates to a transparent glass substrate including at least one glass sheet provided with a thin-film multilayer coating acting on solar radiation, having a light transmission of greater than 10% and an emissivity of less than 50% after a heat treatment, such as a bending or toughening treatment, characterized in that said multilayer coating includes: a niobium Nb functional layer with a thickness of between about 5 nm and about 35 nm; and at least one layer of another material, chosen from the group formed by Ti, Mo, B, Al or an alloy comprising at least one of these elements, which is placed relative to the glass substrate above the functional layer, said layer having a thickness of between about 1 nm and about 5 nm. The invention also relates to monolithic glazing or double glazing incorporating such a substrate.

摘要翻译： 本发明涉及一种透明玻璃基板，包括至少一个设置有作用于太阳辐射的薄膜多层涂层的玻璃板，在热处理后具有大于10％的透光率和小于50％的发射率，例如 作为弯曲或增韧处理，其特征在于，所述多层涂层包括：厚度在约5nm至约35nm之间的铌Nb功能层; 以及选自由Ti，Mo，B，Al形成的组​​或包含这些元素中至少一个的合金的至少一层材料，其相对于功能层上方的玻璃基板放置，所述层具有 在约1nm和约5nm之间的厚度。 本发明还涉及结合这种基板的单片玻璃或双层玻璃。

公开(公告)号：US06743211B1

公开(公告)日：2004-06-01

申请号：US09448107

申请日：1999-11-23

申请人： Mark R. Prausnitz ,  Mark G. Allen ,  Sebastien Henry ,  Devin V. McAllister ,  Donald E. Ackley ,  Thomas Jackson

发明人： Mark R. Prausnitz ,  Mark G. Allen ,  Sebastien Henry ,  Devin V. McAllister ,  Donald E. Ackley ,  Thomas Jackson

IPC分类号： A61M500

CPC分类号： A61M37/0015 ,  A61B5/14514 ,  A61B5/14532 ,  A61B5/150022 ,  A61B5/150068 ,  A61B5/150076 ,  A61B5/150083 ,  A61B5/150099 ,  A61B5/150213 ,  A61B5/150229 ,  A61B5/150389 ,  A61B5/150412 ,  A61B5/150503 ,  A61B5/150984 ,  A61B5/151 ,  A61B17/205 ,  A61M5/422 ,  A61M5/425 ,  A61M2037/0023 ,  A61M2037/003 ,  A61M2037/0053 ,  B33Y80/00

摘要： Microneedle devices and methods of use thereof are provided for the enhanced transport of molecules, including drugs and biological molecules, across tissue by improving the interaction of microneedles and a deformable, elastic biological barrier, such as human skin. The devices and methods act to (1) limit the elasticity, (2) adapt to the elasticity, (3) utilize alternate ways of creating the holes for the microneedles to penetrate the biological barrier, other than the simply direct pressure of the microneedle substrate to the barrier surface, or (4) any combination of these methods. In preferred embodiments for limiting the elasticity of skin, the microneedle device includes features suitable for stretching, pulling, or pinching the skin to present a more rigid, less deformable, surface in the area to which the microneedles are applied (i.e. penetrate). In a preferred embodiments for adapting the device to the elasticity of skin, the device comprising one or more extensions interposed between the substrate and the base end of at least a portion of the microneedles.

摘要翻译： 提供微针装置及其使用方法用于通过改善微针和可变形的弹性生物屏障（例如人皮肤）的相互作用来增强跨组织的分子（包括药物和生物分子）的转运。 装置和方法用于（1）限制弹性，（2）适应弹性，（3）除了微针衬底的简单直接压力之外，利用替代方式产生微针穿透生物屏障的孔 或（4）这些方法的任何组合。 在用于限制皮肤弹性的优选实施例中，微针装置包括适于拉伸，拉伸或夹紧皮肤以在微针施加的区域（即，穿透）上呈现更刚性，更不易变形的表面的特征。 在用于使装置适应皮肤弹性的优选实施例中，该装置包括一个或多个延伸部，该延伸部插入到基底和至少一部分微针的基端之间。

公开(公告)号：US20110027554A1

公开(公告)日：2011-02-03

申请号：US12918518

申请日：2009-02-25

申请人： Eric Gouardes ,  Sebastien Henry ,  Sylvain Belliot

发明人： Eric Gouardes ,  Sebastien Henry ,  Sylvain Belliot

IPC分类号： B32B17/06

CPC分类号： C03C17/40 ,  C03C17/225 ,  C03C17/34 ,  C03C17/36 ,  C03C17/3615 ,  C03C17/3618 ,  C03C17/3626 ,  C03C17/3649 ,  C03C17/3652 ,  C03C17/366 ,  C03C17/3681 ,  Y10T428/2495 ,  Y10T428/24967 ,  Y10T428/315

摘要： The subject of the invention is a transparent glass substrate comprising at least one glass sheet provided with a thin-film multilayer coating acting on solar radiation, having a light transmission of greater than 10% and an emissivity of less than 50% after a heat treatment, such as a bending or toughening treatment, characterized in that said multilayer coating comprises: a niobium Nb functional layer with a thickness of between about 5 nm and about 35 nm; and at least one layer of another material, chosen from the group formed by Ti, Mo, B, Al or an alloy comprising at least one of these elements, which is placed relative to the glass substrate above the functional layer, said layer having a thickness of between about 1 nm and about 5 nm. The invention also relates to monolithic glazing or double glazing incorporating such a substrate.

摘要翻译： 本发明的主题是透明玻璃基板，其包括至少一个设置有作用于太阳辐射的薄膜多层涂层的玻璃板，在热处理后具有大于10％的透光率和小于50％的发射率 ，例如弯曲或增韧处理，其特征在于，所述多层涂层包括：厚度在约5nm至约35nm之间的铌Nb功能层; 以及选自由Ti，Mo，B，Al形成的组​​或包含这些元素中至少一个的合金的至少一层材料，其相对于功能层上方的玻璃基板放置，所述层具有 在约1nm和约5nm之间的厚度。 本发明还涉及结合这种基板的单片玻璃或双层玻璃。

公开(公告)号：US11896452B2

公开(公告)日：2024-02-13

申请号：US16494504

申请日：2018-03-14

申请人： Carestream Dental Technology Topco Limited ,  Delphine Reynard ,  Sabrina Capron-Richard ,  Sebastien Henry ,  Shoupu Chen ,  Aude Lagardere ,  Jean-Pascal Jacob

发明人： Delphine Reynard ,  Sabrina Capron-Richard ,  Sebastien Henry ,  Shoupu Chen ,  Aude Lagardere ,  Jean-Pascal Jacob

IPC分类号： G06T19/00 ,  A61C13/34 ,  G06T7/62 ,  G06T7/149 ,  A61B6/03 ,  A61B6/14 ,  A61B6/00 ,  A61C9/00 ,  G06T7/00 ,  G06T1/20 ,  G06T19/20

CPC分类号： A61C13/34 ,  A61B6/032 ,  A61B6/14 ,  A61B6/145 ,  A61B6/4085 ,  A61C9/0046 ,  G06T1/20 ,  G06T7/0012 ,  G06T7/149 ,  G06T7/62 ,  G06T19/20 ,  G06T2200/24 ,  G06T2207/10081 ,  G06T2207/30036 ,  G06T2219/2021

摘要： A method for visualizing patient dentition acquires a contour image of patient dentition and segments the contour image to identify one or more segmented teeth. At least one deciduous tooth among the one or more segmented teeth is identified. A virtual model of a target dentition arrangement of the patient dentition is generated, wherein the at least one deciduous tooth is replaced by a replacement permanent tooth.

公开(公告)号：US06606768B2

公开(公告)日：2003-08-19

申请号：US10072740

申请日：2002-02-08

申请人： Sebastien Henry ,  Renee Buisson Pultar

发明人： Sebastien Henry ,  Renee Buisson Pultar

IPC分类号： A45F500

CPC分类号： A61J9/06 ,  A45F5/00 ,  A45F2005/006 ,  A47G21/00 ,  B62B3/1456 ,  Y10T24/1397 ,  Y10T24/2708 ,  Y10T24/31

摘要： A strap device is provided for holding objects held by infants, for preventing the object from falling to the ground if released by the infant. The strap device includes a flexible strap having a first end with a first securing means, a second end with a second securing means, a first attachment means mounted on the flexible strap near the first end, and a second attachment means mounted on the flexible strap near the second end. The attachment means each can be releasably secured to a position on the flexible strap, forming a primary loop for securing the flexible strap to the object or to a support structure. The first securing means preferably is an elastic loop, which can attach the object to the strap device regardless of the object's shape and dimensions, while the second securing means attaches to a support near the infant for his use.

公开(公告)号：US06503231B1

公开(公告)日：2003-01-07

申请号：US09095221

申请日：1998-06-10

申请人： Mark R. Prausnitz ,  Mark G. Allen ,  Devin V. McAllister ,  Sebastien Henry

发明人： Mark R. Prausnitz ,  Mark G. Allen ,  Devin V. McAllister ,  Sebastien Henry

IPC分类号： A61M532

CPC分类号： B81C1/00111 ,  A61B5/14514 ,  A61B5/14532 ,  A61B5/150022 ,  A61B5/150282 ,  A61B5/150984 ,  A61B17/205 ,  A61B2010/008 ,  A61K9/0021 ,  A61M37/0015 ,  A61M2037/003 ,  A61M2037/0053 ,  A61N1/303 ,  B33Y80/00 ,  B81B2201/055

摘要： Microneedle devices for transport of therapeutic and diagnostic materials and/or energy across tissue barriers, and methods for manufacturing the devices, are provided. The microneedles are hollow and/or porous and have diameters between about 10 nm and 1 mm. The microneedle devices permit drug delivery (or removal or sensing of body fluids) at clinically relevant rates across skin or other tissue barriers, without damage, pain, or irritation to the tissue. Microfabrication techniques are used to cost-effectively produce arrays of microneedles from metals, silicon, silicon dioxide, ceramic, and polymeric materials. Methods are provided for making porous or hollow microneedles.

摘要翻译： 提供了用于在组织屏障上传送治疗和诊断材料和/或能量的微针装置，以及用于制造装置的方法。 微针是中空的和/或多孔的并且具有在约10nm和1mm之间的直径。 微针装置允许在皮肤或其他组织屏障上的临床相关速率的药物递送（或去除或感测体液），而不会对组织造成伤害，疼痛或刺激。 微加工技术用于经济高效地从金属，硅，二氧化硅，陶瓷和聚合物材料制造微针阵列。 提供用于制造多孔或中空微针的方法。