-
公开(公告)号：US12099049B2
公开(公告)日：2024-09-24
申请号：US17686250
申请日：2022-03-03
发明人： Wenbo Zheng , Bo Ye , Wentao Wei
CPC分类号： G01N33/49 , G01N1/4044
摘要： Provided are a method and device for recognizing hook effect in immune turbidimetry, and a computer readable medium. This method generates a reaction curve using light signals measured in a predetermined time period by immune reaction of analyte in a sample, and uses distribution information of the reaction curve in the predetermined time period to determine whether the sample has hook effect. This method only uses measurement information of a small predetermined time period in entire reaction time to determine whether a sample has hook effect, and terminates the test in time, thus accelerating the speed of immune turbidimetry detection of samples with hook effect.
-
公开(公告)号：US11781983B2
公开(公告)日：2023-10-10
申请号：US17078705
申请日：2020-10-23
发明人： Huan Qi , Wenbo Zheng , Bo Ye , Zhaoyang Li , Yi Ye
IPC分类号： G01N33/80 , G01N15/14 , G01N15/00 , G01N21/64 , G01N15/06 , G01N21/47 , G01N27/02 , G01N33/487 , G08B21/18
CPC分类号： G01N21/6428 , G01N15/06 , G01N15/1429 , G01N15/1436 , G01N21/47 , G01N27/02 , G01N33/48707 , G01N33/80 , G08B21/185 , G01N15/1404 , G01N2015/008 , G01N2015/0069 , G01N2015/0084 , G01N2015/0693 , G01N2015/1402 , G01N2021/6439
摘要： A method, system and storage medium for providing an alarm for indicating that an abnormality is present in a sample analyzer are provided. The method includes: mixing a first aliquot of a blood sample with a diluent agent to prepare a first test sample; mixing a second aliquot of the blood sample with a lytic reagent to prepare a second test sample; detecting electrical impedance signals of the first test sample; detecting at least two types of optical signals of the second test sample; acquiring first platelet detection data based on the electrical impedance signals; acquiring second platelet detection data based on the at least two types of optical signals; acquiring an evaluation result based on a difference between the first platelet detection data and the second platelet detection data; determining whether the evaluation result meets a preset condition to provide an alarm.
-
公开(公告)号：US12046333B2
公开(公告)日：2024-07-23
申请号：US17986726
申请日：2022-11-14
发明人： Bo Ye , Changsong Hu , Huan Qi , Wenbo Zheng
CPC分类号： G16B45/00 , G01N1/14 , G01N1/31 , G01N15/1459 , G01N33/5094 , G01N2001/1418 , G01N2015/016 , G01N2015/018 , G01N2015/1486
摘要： A blood cell analysis method and a blood cell analyzer are provided. In the method and analyzer, characteristic information of white blood cell fragments is obtained based on side scattered light information and fluorescence information, characteristic information of platelets is obtained based on forward scattered light information and fluorescence information and then a count value for the platelets is acquired based on the characteristic information of the platelets and the characteristic information of the white blood cell fragments. The present invention can avoid the influence of the white blood cell fragments on the platelet counting, thereby ensuring the accuracy of the platelet counting without increasing costs.
-
公开(公告)号：US11874212B2
公开(公告)日：2024-01-16
申请号：US17078740
申请日：2020-10-23
发明人： Bo Ye , Wenbo Zheng , Huan Qi , Zhaoyang Li
CPC分类号： G01N15/1429 , G01N15/1031 , G01N33/49
摘要： A blood analysis method, a blood analysis system, and a storage medium are provided. The blood analysis method includes: providing a blood sample; mixing a first aliquot of the blood sample with a diluent to prepare a first test sample; mixing a second aliquot of the blood sample with a lytic reagent to prepare a second test sample; detecting electrical impedance signals of the first test sample to obtain first volume distribution data; detecting at least two types of optical signals of the second test sample to obtain second volume distribution data; acquiring red blood cell test data of the blood sample; determining, based on the first volume distribution data, the second volume distribution data, and the red blood cell test data, whether the blood sample contains schistocytes; and if the determination result is yes, providing a warning that the blood sample may contain schistocytes.
-
公开(公告)号：US11841358B2
公开(公告)日：2023-12-12
申请号：US17075603
申请日：2020-10-20
发明人： Huan Qi , Bo Ye , Wenbo Zheng , Changsong Hu , Qi Yu
IPC分类号： C12Q1/00 , G01N33/49 , G16H40/67 , G16H10/40 , G16H15/00 , G01N15/06 , G01N33/487 , G01N15/00
CPC分类号： G01N33/49 , G01N15/0656 , G01N33/48707 , G16H10/40 , G16H15/00 , G16H40/67 , G01N2015/0084 , G01N2015/0693
摘要： Disclosed are a method for determining a platelet concentration of a blood sample, a hematology system (100) and a storage medium. The method for determining a platelet concentration in a blood sample includes: forming a first suspension by mixing a first aliquot of the blood sample with a diluent; forming a second suspension by mixing a second aliquot of the blood sample with a lytic agent and a fluorescent dye to lyse red blood cells and stain white blood cells; measuring DC impedance signals of the first suspension passing through an aperture; measuring light scatter signals and fluorescent signals of the second suspension passing through an optical flow cell (20); analyzing DC impedance signals of the first suspension to obtain a first platelet distribution; analyzing light scatter signals and fluorescent signals of the second suspension to differentiate platelets from white blood cells and to obtain a second platelet distribution; and determining platelet data, such as the platelet concentration of the blood sample using the first and second platelet distributions.
-
公开(公告)号：US11501852B2
公开(公告)日：2022-11-15
申请号：US16542267
申请日：2019-08-15
发明人： Bo Ye , Changsong Hu , Huan Qi , Wenbo Zheng
摘要： A blood cell analysis method and a blood cell analyzer are provided. In the method and analyzer, characteristic information of white blood cell fragments is obtained based on side scattered light information and fluorescence information, characteristic information of platelets is obtained based on forward scattered light information and fluorescence information and then a count value for the platelets is acquired based on the characteristic information of the platelets and the characteristic information of the white blood cell fragments. The present invention can avoid the influence of the white blood cell fragments on the platelet counting, thereby ensuring the accuracy of the platelet counting without increasing costs.
-
公开(公告)号：US11125687B2
公开(公告)日：2021-09-21
申请号：US16537674
申请日：2019-08-12
发明人： Wenbo Zheng , Bo Ye , Huan Qi , Shan Yu , Xiujuan Li , Zhaoyang Li
摘要： A method for identifying fragmented red blood cells comprising: acquiring side scatter light signals and fluorescence signals of cell particles in a sample liquid; and distinguishing and identifying a fragmented red blood cell population from the cell particles according to the side scatter light signals and the fluorescence signals of the cell particles. The fragmented red blood cell population can be identified from the cell particles by processing and analyzing the side scatter light signals and fluorescence signals of the sample liquid. The present application further provides a device for identifying fragmented red blood cells, a blood cell analyzer and an analysis method. Fragmented red blood cells can be identified according to the fluorescence that characterizes a nucleic acid content in a cell particle and the side scatter light, thus reducing errors in identification and counting.
-
-
-
-
-
-
搜索结果
7 条记录 (耗时 0.02 秒)
