-
公开(公告)号：US12046333B2
公开(公告)日：2024-07-23
申请号：US17986726
申请日：2022-11-14
发明人： Bo Ye , Changsong Hu , Huan Qi , Wenbo Zheng
CPC分类号： G16B45/00 , G01N1/14 , G01N1/31 , G01N15/1459 , G01N33/5094 , G01N2001/1418 , G01N2015/016 , G01N2015/018 , G01N2015/1486
摘要： A blood cell analysis method and a blood cell analyzer are provided. In the method and analyzer, characteristic information of white blood cell fragments is obtained based on side scattered light information and fluorescence information, characteristic information of platelets is obtained based on forward scattered light information and fluorescence information and then a count value for the platelets is acquired based on the characteristic information of the platelets and the characteristic information of the white blood cell fragments. The present invention can avoid the influence of the white blood cell fragments on the platelet counting, thereby ensuring the accuracy of the platelet counting without increasing costs.
-
公开(公告)号：US11709123B2
公开(公告)日：2023-07-25
申请号：US17353406
申请日：2021-06-21
发明人： Guanzhen Wang , Bo Ye , Huan Qi
CPC分类号： G01N15/14 , G01N21/64 , G01N2015/0069 , G01N2015/0073 , G01N2015/1481
摘要： A method for analyzing nucleated red blood cells in a blood sample includes obtaining fluorescence signals and scattered light signals of cells in a blood sample; classifying and counting ghost particles, white blood cells, and nucleated red blood cells in the blood sample according to the fluorescence signals and the scattered light signals; obtaining a characteristic value of a characteristic particle population related to the nucleated red blood cells; and ascertaining a final nucleated red blood cell detection result according to the classifying and counting result of the nucleated red blood cells and the characteristic value of the characteristic particle group.
-
公开(公告)号：US12042277B2
公开(公告)日：2024-07-23
申请号：US16729161
申请日：2019-12-27
发明人： Xuerong Li , Huilin Shi , Jianchao Liu , Bo Ye
IPC分类号： A61B5/145 , G01N15/01 , G01N15/14 , G01N15/1404 , G01N21/64
CPC分类号： A61B5/14535 , G01N15/1404 , G01N21/64 , G01N2015/012 , G01N2015/018 , G01N2015/1486
摘要： A blood detection method and a blood detection device are disclosed. When a count number of platelet in a blood sample is less than a predetermined value, a detection solution of the blood sample is prepared. A cell statistical amount of the detection solution of the blood sample is increased to obtain the platelet detection result. The cell statistics amount of the detection solution of the blood sample may be increased in an impedance detection area to perform PLT-I detection, or in an RET detection area; or performing both of RET detection and PLT-O detection simultaneously. Thus, the accuracy of platelet detection can be improved when the number of platelets in the blood sample is low.
-
公开(公告)号：US11781983B2
公开(公告)日：2023-10-10
申请号：US17078705
申请日：2020-10-23
发明人： Huan Qi , Wenbo Zheng , Bo Ye , Zhaoyang Li , Yi Ye
IPC分类号： G01N33/80 , G01N15/14 , G01N15/00 , G01N21/64 , G01N15/06 , G01N21/47 , G01N27/02 , G01N33/487 , G08B21/18
CPC分类号： G01N21/6428 , G01N15/06 , G01N15/1429 , G01N15/1436 , G01N21/47 , G01N27/02 , G01N33/48707 , G01N33/80 , G08B21/185 , G01N15/1404 , G01N2015/008 , G01N2015/0069 , G01N2015/0084 , G01N2015/0693 , G01N2015/1402 , G01N2021/6439
摘要： A method, system and storage medium for providing an alarm for indicating that an abnormality is present in a sample analyzer are provided. The method includes: mixing a first aliquot of a blood sample with a diluent agent to prepare a first test sample; mixing a second aliquot of the blood sample with a lytic reagent to prepare a second test sample; detecting electrical impedance signals of the first test sample; detecting at least two types of optical signals of the second test sample; acquiring first platelet detection data based on the electrical impedance signals; acquiring second platelet detection data based on the at least two types of optical signals; acquiring an evaluation result based on a difference between the first platelet detection data and the second platelet detection data; determining whether the evaluation result meets a preset condition to provide an alarm.
-
公开(公告)号：US10983042B2
公开(公告)日：2021-04-20
申请号：US16801544
申请日：2020-02-26
发明人： Bo Ye , Guanzhen Wang , Jiantao Di , Ying Zhang , Huan Qi
摘要： A cell analyzer and a sorting method for the cell analyzer are disclosed. Multiple optical signals generated by each of particles irradiated with light in a blood sample in a detection region are collected. The particles includes a first category of particles and a second category of particles. For each of the particles, Intensities of a first group of optical signals, which includes at least two optical signals selected from the multiple optical signals, and a pulse width of a second group of optical signals, which includes at least one optical signal selected from the multiple optical signals are acquired. For each of the particles, one or more reinforcement signals related to the particle are calculated based on an intensity of a first optical signal selected from the first group of optical signals and a pulse width of a second optical signal selected from the second group of optical signals, where the first optical signal is as same as or different from the second optical signal. The first category of particles and the second category of particles are distinguished from each other based at least partially on the one or more reinforcement signals related to each of the particles.
-
公开(公告)号：US20200209224A1
公开(公告)日：2020-07-02
申请号：US16814846
申请日：2020-03-10
发明人： Bo Ye , Cheng Qian , Huan Qi
摘要： The present disclosure relates to the field of medical technology, which provides methods and apparatuses for identifying red blood cells infected by plasmodium. The methods may include: obtaining a forward-scattered light signal, a side-scattered light signal and an optional fluorescence signal from cells in a blood sample; obtaining a first two-dimensional scattergram according to the forward-scattered light signal and the side-scattered light signal, or obtaining a three-dimensional scattergram according to the forward-scattered light signal, the side-scattered light signal and the fluorescence signal; and identifying cells located in a predetermined area of the first two-dimensional scattergram or the three-dimensional scattergram as the red blood cells infected by plasmodium. The apparatuses perform the methods. The methods and apparatuses can have better identification accuracy.
-
公开(公告)号：US10656143B2
公开(公告)日：2020-05-19
申请号：US14355544
申请日：2012-10-31
发明人： Bo Ye , Cheng Qian , Huan Qi
摘要： The present disclosure relates to the field of medical technology, which provides methods and apparatuses for identifying red blood cells infected by plasmodium. The methods may include: obtaining a forward-scattered light signal, a side-scattered light signal and an optional fluorescence signal from cells in a blood sample; obtaining a first two-dimensional scattergram according to the forward-scattered light signal and the side-scattered light signal, or obtaining a three-dimensional scattergram according to the forward-scattered light signal, the side-scattered light signal and the fluorescence signal; and identifying cells located in a predetermined area of the first two-dimensional scattergram or the three-dimensional scattergram as the red blood cells infected by plasmodium. The apparatuses perform the methods. The methods and apparatuses can have better identification accuracy.
-
公开(公告)号：US12099049B2
公开(公告)日：2024-09-24
申请号：US17686250
申请日：2022-03-03
发明人： Wenbo Zheng , Bo Ye , Wentao Wei
CPC分类号： G01N33/49 , G01N1/4044
摘要： Provided are a method and device for recognizing hook effect in immune turbidimetry, and a computer readable medium. This method generates a reaction curve using light signals measured in a predetermined time period by immune reaction of analyte in a sample, and uses distribution information of the reaction curve in the predetermined time period to determine whether the sample has hook effect. This method only uses measurement information of a small predetermined time period in entire reaction time to determine whether a sample has hook effect, and terminates the test in time, thus accelerating the speed of immune turbidimetry detection of samples with hook effect.
-
公开(公告)号：US12055472B2
公开(公告)日：2024-08-06
申请号：US17356332
申请日：2021-06-23
发明人： Bo Ye , Guanzhen Wang , Jin Li
CPC分类号： G01N15/10 , G01N15/01 , G01N2015/03 , G01N2015/1486 , G01N2015/1493
摘要： A blood cell parameter correction method includes: obtaining the optical signal information of the particles in the blood sample; according to the pulse width information in the optical signal information, dividing the particles in the blood sample to obtain particle distribution information; according to the preset correction rule, correcting the particle distribution information to obtain the corrected particle distribution information; wherein, the correction rule is related to the pulse width information in the optical signal information, and provided is also a blood sample analyzer executing the method, and storage medium storing the program executing the method.
-
公开(公告)号：US11105742B2
公开(公告)日：2021-08-31
申请号：US15638902
申请日：2017-06-30
发明人： Bo Ye , Huan Qi , Cheng Qian
摘要： Disclosed are nucleated red blood cell warning devices and methods, and flow cytometers using the same. The devices, methods and flow cytometers can warn whether nucleated red blood cells exist in a blood sample. The warning device may obtain forward-scattered light information, side-scattered light information and fluorescence information when cells in the blood sample pass through a detection region of the flow cytometer. The warning device may generate a side-scattered light-fluorescence dot plot, so as to classify leucocytes into four groups, and may generate a forward-scattered light-fluorescence dot plot, where the forward-scattered light-fluorescence dot plot can include a leucocyte group region. The warning device may obtain a predetermined feature region located at the left side of the leucocyte group region, perform statistics on the amount of characterization cells in the predetermined feature region, and provide a warning when the number of the characterization cells exceeds a threshold value.
-
-
-
-
-
-
-
-
-
搜索结果
19 条记录 (耗时 0.035 秒)
