Substrate for forming a three-dimensional tissue construct and method of use
    3.
    发明授权
    Substrate for forming a three-dimensional tissue construct and method of use 有权
    用于形成三维组织结构的基材和使用方法

    公开(公告)号:US08815595B2

    公开(公告)日:2014-08-26

    申请号:US12033324

    申请日:2008-02-19

    IPC分类号: C12M3/00

    摘要: The present invention provides a tissue construct-forming substrate for forming a three-dimensional tissue construct containing proliferating cells, the substrate including a porous film having through-holes, and the porous film having, on the surface of the film, a cell adhesive region capable of retaining cells and a cell non-adhesive region located at a peripheral region of the cell adhesive region, a tissue construct-forming kit comprising the above-mentioned tissue construct-forming substrate and a frame, and a method for forming the above-mentioned tissue construct.

    摘要翻译: 本发明提供了一种用于形成含有增殖细胞的三维组织构建体的组织构建体形成基底,所述基底包括具有通孔的多孔膜,并且所述多孔膜在所述膜的表面上具有细胞粘附区域 能够保持细胞和位于细胞粘附区域的周边区域的细胞非粘合剂区域,包含上述组织构建体形成基材和框架的组织构建体形成试剂盒,以及形成上述组织构建体形成基板的方法, 上述组织构建体。

    PRODUCTION METHOD OF POROUS FILM, AND POROUS FILM, COMPOSITE MATERIAL
    8.
    发明申请
    PRODUCTION METHOD OF POROUS FILM, AND POROUS FILM, COMPOSITE MATERIAL 审中-公开
    多孔膜的制备方法和多孔膜,复合材料

    公开(公告)号:US20100196694A1

    公开(公告)日:2010-08-05

    申请号:US12679500

    申请日:2008-09-19

    IPC分类号: B32B3/10 B01D67/00 B32B3/26

    摘要: A solution (11) containing an organic solvent, a polymer and a plasticizer (TPP, BDP or the like) which is not less than 0.01 wt. % and not more than 50 wt. % of the polymer is cast onto an endless belt (51) to be a casting film (22). Water vapor is condensed from ambient gas on a surface of the casting film (22) passing through a first area (46) to form water drops. The water drops on the casting film (22) passing through a second area (47) are grown and the organic solvent thereof is evaporated. The water drops on the casting film (22) passing through a third area (48) are evaporated. The casting film (22) after passing through the third area (48) is peeled from the endless belt (51) as a flexible porous film (17) by a peel roller (57).

    摘要翻译: 含有不少于0.01重量%的有机溶剂,聚合物和增塑剂(TPP,BDP等)的溶液(11) %且不超过50wt。 将聚合物的%浇铸到环形带(51)上以成为流延薄膜(22)。 水蒸汽通过第一区域(46)在流延膜(22)的表面上从环境气体中冷凝,形成水滴。 生长通过第二区域(47)的流延膜(22)上的水滴,并且其有机溶剂蒸发。 通过第三区域(48)的流延膜(22)上的水滴蒸发。 通过第三区域(48)之后的流延膜(22)通过剥离辊(57)作为柔性多孔膜(17)从环形带(51)剥离。