公开(公告)号：US06885972B2

公开(公告)日：2005-04-26

申请号：US10229005

申请日：2002-08-28

申请人： Shuichi Samata ,  Yukihiro Ushiku ,  Takeo Furuhata ,  Takashi Nakao ,  Ken Ishii

发明人： Shuichi Samata ,  Yukihiro Ushiku ,  Takeo Furuhata ,  Takashi Nakao ,  Ken Ishii

IPC分类号： F04B51/00 ,  G05B19/4065 ,  H01L21/02 ,  G06F19/00

CPC分类号： G05B19/4065 ,  G05B2219/37252 ,  Y02P90/86

摘要： A method for predicting life span of a rotary machine used in a manufacturing apparatus, includes: measuring rotary machine acceleration evaluation time series data with a sampling interval being less than a half the cycle of an analysis target frequency, a number of samplings being at least four times the analysis target frequency; generating evaluation diagnosis data based on variations in characteristics corresponding to the analysis target frequency by subjecting the evaluation time series data to frequency analysis; and determining the life span of the rotary machine using the evaluation diagnosis data.

摘要翻译： 一种用于预测制造装置中使用的旋转机械的使用寿命的方法，包括：以取样间隔小于分析对象频率的周期的一半来测量旋转机械加速度评价时间序列数据，取样次数至少为 四倍分析目标频率; 通过对评价时间序列数据进行频率分析，生成基于与分析对象频率对应的特性的变化的评价诊断数据; 以及使用评估诊断数据确定所述旋转机器的使用寿命。

公开(公告)号：US06937963B2

公开(公告)日：2005-08-30

申请号：US10228110

申请日：2002-08-27

申请人： Ken Ishii ,  Takashi Nakao ,  Yukihiro Ushiku ,  Shuichi Samata

发明人： Ken Ishii ,  Takashi Nakao ,  Yukihiro Ushiku ,  Shuichi Samata

IPC分类号： F04B49/10 ,  C23C16/52 ,  F04B51/00 ,  G05B9/02 ,  G05B23/02 ,  H01L21/02 ,  H01L21/31 ,  G06F11/30 ,  G06F15/00 ,  G21C17/00

CPC分类号： G05B9/02 ,  G05B23/024 ,  G05B23/0291

摘要： A method for avoiding irregular shutoff of production equipment, includes: measuring regularly time-series data of characteristics of a rotary machine used in the production equipment running for the production; obtaining first failure diagnosis data subjecting the time-series data to a first real-time analysis; obtaining second failure diagnosis data subjecting the first failure diagnosis data to a second real-time analysis; predicting a status of the production equipment several minutes later using the second failure diagnosis data; and shutting off during a production process if the result of the prediction determines that the production equipment will shut off irregularly, and switching to a purge sequence for conducting a gas purge of the production equipment.

摘要翻译： 一种避免生产设备不规则关闭的方法，包括：定期测量生产设备运行中使用的旋转机械特性的时间序列数据; 获得对时间序列数据进行第一次实时分析的第一故障诊断数据; 获得第一故障诊断数据进行第二实时分析的第二故障诊断数据; 几分钟后使用第二次故障诊断数据预测生产设备的状态; 如果预测结果确定生产设备将不规则地关闭，并切换到用于进行生产设备的气体吹扫的吹扫序列，则在生产过程中关闭。

公开(公告)号：US06909993B2

公开(公告)日：2005-06-21

申请号：US10228960

申请日：2002-08-28

申请人： Takashi Nakao ,  Yukihiro Ushiku ,  Shuichi Samata ,  Hiroshi Akahori ,  Ken Ishii

发明人： Takashi Nakao ,  Yukihiro Ushiku ,  Shuichi Samata ,  Hiroshi Akahori ,  Ken Ishii

IPC分类号： G05B19/418 ,  G05B23/02 ,  G06F11/30 ,  G06F17/00 ,  G21C17/00 ,  H01L21/00 ,  H01L21/02 ,  H01L21/31

CPC分类号： G05B23/024 ,  Y02P90/86

摘要： A method for diagnosing failure of a manufacturing apparatus, includes: measuring time series data of characteristics of a reference apparatus which conducts same processes as the manufacturing apparatus, and recording the time series data of the characteristics in a system information storage unit as a system information database; reading out a recipe listed in a process control information database recorded in a process control information storage unit; driving and controlling the manufacturing apparatus, measuring time series data of the characteristics as test data, and outputting the test data in real time, in accordance with the recipe; performing calculations on the test data, and creating failure diagnosis data; and diagnosing the failure of the manufacturing apparatus using the failure diagnosis data and the system information database.

摘要翻译： 一种用于诊断制造装置的故障的方法，包括：测量与制造装置进行相同处理的参考装置的特性的时间序列数据，并将该特性的时间序列数据记录在系统信息存储单元中作为系统信息 数据库; 读出记录在过程控制信息存储单元中的过程控制信息数据库中列出的配方; 驱动和控制制造装置，测量特性的时间序列数据作为测试数据，并根据配方实时输出测试数据; 对测试数据执行计算，并创建故障诊断数据; 以及使用故障诊断数据和系统信息数据库诊断制造装置的故障。

公开(公告)号：US06766275B2

公开(公告)日：2004-07-20

申请号：US10228111

申请日：2002-08-27

申请人： Shuichi Samata ,  Yukihiro Ushiku ,  Ken Ishii ,  Takashi Nakao

发明人： Shuichi Samata ,  Yukihiro Ushiku ,  Ken Ishii ,  Takashi Nakao

IPC分类号： G06F1900

CPC分类号： G05B23/0283

摘要： A method for diagnosing life of manufacturing equipment having a rotary machine, includes: measuring reference time series data for characteristics before deterioration of the manufacturing equipment occurs; finding a reference auto covariance function based on the reference time series data; extracting a reference variation caused by variations of the process condition and power supply from the reference auto covariance function, and calculating a cycle of the reference variation; measuring diagnostic time series data for the characteristics in a sequence to be measured of the manufacturing equipment; finding a diagnostic auto covariance function based on the diagnostic time series data; and determining the life of the manufacturing equipment from the diagnostic auto covariance function using a component with a cycle shorter than a cycle of the reference variation.

摘要翻译： 一种用于诊断具有旋转机器的制造设备的寿命的方法，包括：测量制造设备劣化之前的特性的基准时间序列数据; 基于参考时间序列数据找到参考自动协方差函数; 从参考自动协方差函数中提取由过程条件和电源的变化引起的参考变化，并计算参考变化的周期; 测量制造设备要测量的序列中的特性的诊断时间序列数据; 基于诊断时间序列数据找到诊断自动协方差函数; 以及使用周期短于参考变化的周期的分量从诊断自动协方差函数确定制造设备的寿命。

公开(公告)号：US20120186604A1

公开(公告)日：2012-07-26

申请号：US13233190

申请日：2011-09-15

申请人： Kensuke Takano ,  Shinji Miyazaki ,  Ken Ishii ,  Takashi Nakao

发明人： Kensuke Takano ,  Shinji Miyazaki ,  Ken Ishii ,  Takashi Nakao

IPC分类号： B08B5/00 ,  H01L21/3065

CPC分类号： C23C16/52 ,  C23C16/4405

摘要： According to one embodiment, a cleaning gas is sealed in a chamber of a semiconductor manufacturing apparatus, and the cleaning gas and deposits adhered in the chamber are reacted with each other to generate a reactive gas. After a predetermined time, the gas is exhausted from the chamber. Then, the chamber is evacuated while the cleaning gas is introduced into the chamber, and the reactive gas concentration contained in an exhausted gas is measured. The reactive gas concentration is compared with a determination value obtained when the deposits are removed from the chamber to determine whether the cleaning is terminated.

摘要翻译： 根据一个实施例，将清洁气体密封在半导体制造装置的室中，并且附着在室中的清洁气体和沉积物彼此反应以产生反应性气体。 在预定时间之后，气体从腔室排出。 然后，在将清洁气体引入室内的同时将室抽真空，并测量排出气体中所含的反应气体浓度。 将反应气体浓度与从室中移出沉积物时获得的确定值进行比较，以确定清洁是否终止。

公开(公告)号：US10130398B2

公开(公告)日：2018-11-20

申请号：US15329740

申请日：2015-06-29

申请人： KYOCERA Medical Corporation ,  Ken Ishii ,  Morio Matsumoto ,  Yoshiaki Toyama

发明人： Ken Ishii ,  Morio Matsumoto ,  Yoshiaki Toyama ,  Masaki Atarashi ,  Junji Ito

IPC分类号： A61B17/70 ,  A61B17/86 ,  A61B17/88

摘要： A vertebral surgery instrument includes: an engagement part for engaging with a pair of opposing parts provided on or attached to a vertebral implant in a state in which the vertebral implant is fixed to a vertebra, the pair of opposing parts forming a slit into which a fixation rod for fixing a plurality of vertebrae to each other is to be inserted; and a pair of guide parts that are provided integrally with or attached to the engagement part. The pair of guide parts are formed extending so as to separate from each other toward a side on which the fixation rod is to be inserted, in a state in which the engagement part is engaged with the pair of opposing parts, and the slit and a guide passage that is formed between the pair of guide parts are in communication with each other.

公开(公告)号：US20130008222A1

公开(公告)日：2013-01-10

申请号：US13635476

申请日：2011-03-18

申请人： Takahiro Ota ,  Daisuke Ogura ,  Atsushi Sugai ,  Ken Ishii

发明人： Takahiro Ota ,  Daisuke Ogura ,  Atsushi Sugai ,  Ken Ishii

IPC分类号： B21D11/20 ,  B32B1/00

CPC分类号： B21D11/08 ,  B21D11/02 ,  B21D11/206 ,  Y10T428/1241

摘要： Provided is a molding method for a plate-shaped workpiece including forming a concave portion (11) at one surface (1a) of a plate-shaped workpiece (1), and bending the plate-shaped workpiece (1) having the concave portion (11) such that the one surface (1a) becomes a concave surface and a rear surface (1b) thereof becomes a convex surface.

摘要翻译： 本发明提供一种板状工件的成型方法，其包括在板状工件（1）的一个表面（1a）处形成凹部（11），并弯曲具有凹部的板状工件（1） 11），使得一个表面（1a）变成凹面，并且其后表面（1b）变为凸面。

公开(公告)号：US20120128725A1

公开(公告)日：2012-05-24

申请号：US13312260

申请日：2011-12-06

申请人： Shizuo Akira ,  Ken Ishii ,  Cevayir Coban

发明人： Shizuo Akira ,  Ken Ishii ,  Cevayir Coban

IPC分类号： A61K31/555 ,  C12N5/071 ,  A61K38/02

CPC分类号： A61K39/015 ,  A01K2267/0387 ,  A61K2039/572 ,  G01N33/56905 ,  G01N2333/445 ,  G01N2333/70596 ,  G01N2500/10 ,  Y02A50/58

摘要： The instant invention is to provide a method for detecting and measuring malaria infection utilizing the induction by hemozoin (HZ); a method for screening a vaccine for malaria infection and a preventative or therapeutic agent for malaria infection using the method for detecting and measuring; and a means for regulating the induction of innate immunity using the HZ, synthetic HZ, or derivatives thereof as an adjuvant or immunostimulant. Malaria infection is detected and measured of by detecting and measuring HZ-induced, TLR9-mediated, and MyD88-dependent innate immune activity. The detection and measurement of malaria infection can be used to diagnose malaria infection. The method for detecting and measuring is also used for screening a vaccine for malaria infection and a preventative or therapeutic agent for malaria infection. Further, HZ, synthetic HZ, or derivatives thereof are used as an adjuvant or immunostimulant to regulate HZ-induced innate immune induction.

摘要翻译： 本发明是提供一种利用血红素（HZ）的诱导检测和测量疟疾感染的方法; 使用检测和测量方法筛选疟疾感染疫苗的方法和用于疟疾感染的预防或治疗剂; 以及使用HZ，合成HZ或其衍生物作为佐剂或免疫刺激剂来调节诱导天然免疫的方法。 通过检测和测量HZ诱导的TLR9介导的和MyD88依赖性先天免疫活性来检测和测量疟疾感染。 疟疾感染的检测和测量可用于诊断疟疾感染。 用于检测和测量的方法也用于筛选疟疾感染的疫苗和用于疟疾感染的预防或治疗剂。 此外，HZ，合成HZ或其衍生物用作佐剂或免疫刺激剂以调节HZ诱导的先天免疫诱导。

公开(公告)号：US20120064132A1

公开(公告)日：2012-03-15

申请号：US13321215

申请日：2010-05-19

申请人： Mamoru Aizawa ,  Tomoyuki Hoshikawa ,  Ken Ishii ,  Haruki Funao

发明人： Mamoru Aizawa ,  Tomoyuki Hoshikawa ,  Ken Ishii ,  Haruki Funao

IPC分类号： A61K9/00 ,  A61P31/04 ,  C07F1/10 ,  A61K31/6615 ,  C07F9/117

CPC分类号： A61L27/12 ,  A61L27/54 ,  A61L29/02 ,  A61L29/16 ,  A61L31/026 ,  A61L31/16 ,  A61L2300/104 ,  A61L2300/112 ,  A61L2300/404 ,  A61L2300/606

摘要： An object of the present invention is to provide an antibacterial medical equipment which has sufficient antibacterial activity in vivo and is excellent in compatibility with living tissues, and also can maintain antibacterial activity over a long period and has high safety.An antibacterial medical equipment characterized in that inositol phosphate is bonded to a Ca compound of a medical equipment whose surface is at least coated with a layer of the Ca compound, or a medical equipment comprising the Ca compound. The antibacterial medical equipment as described above, wherein silver ions are bonded to the inositol phosphate. A method for producing an antibacterial medical equipment, which comprises bringing a medical equipment whose surface is at least coated with a layer of a Ca compound, or a medical equipment comprising a Ca compound into contact with an aqueous solution of inositol phosphate to obtain an antibacterial medical equipment in which inositol phosphate is bonded to the Ca compound. The method for producing an antibacterial medical equipment, wherein inositol phosphate is bonded to the Ca compound and then the Ca compound is brought into contact with an aqueous solution containing silver ions to obtain an antibacterial medical equipment in which silver ions are bonded to the inositol phosphate.

摘要翻译： 本发明的目的在于提供一种在体内具有足够的抗菌活性并且与活组织相容性优异的抗菌医疗设备，并且能够长时间保持抗菌活性且安全性高。 一种抗菌医疗设备，其特征在于磷酸肌醇与其表面至少涂覆有Ca化合物层的医疗设备的Ca化合物或包含Ca化合物的医疗设备结合。 如上所述的抗菌医疗设备，其中银离子与磷酸肌醇结合。 一种抗菌医疗设备的制造方法，其特征在于，将表面至少涂覆有Ca化合物的医疗器械，或包含Ca化合物的医疗器械与磷酸肌醇水溶液接触，得到抗菌剂 磷酸肌醇与Ca化合物结合的医疗设备。 生产抗菌医疗设备的方法，其中将磷酸肌醇与Ca化合物接合，然后使Ca化合物与含有银离子的水溶液接触，得到银离子与磷酸肌醇结合的抗菌医疗设备 。

公开(公告)号：US07960356B2

公开(公告)日：2011-06-14

申请号：US11131672

申请日：2005-05-17

申请人： Dennis Klinman ,  Daniela Verthelyi ,  Ken Ishii ,  James J. Mond ,  Mayda Gursel

发明人： Dennis Klinman ,  Daniela Verthelyi ,  Ken Ishii ,  James J. Mond ,  Mayda Gursel

IPC分类号： A61K39/00 ,  A61K39/38 ,  A61K45/00 ,  A61K47/00 ,  A61K31/70 ,  A61K9/127 ,  A01N43/04

CPC分类号： A61K39/008 ,  A61K31/7088 ,  A61K39/39 ,  A61K2039/55561 ,  C07H21/04 ,  Y02A50/41 ,  A61K2300/00

摘要： D type CpG oligodeoxynucleotides are provided herein that include a sequence represented by the following formula: 5′ X1X2X3Pu1 Py2 CpG Pu3 Py4 X4X5X6(W)M (G)N-3′ wherein the central CpG motif is unmethylated, Pu is a purine nucleotide, Py is a pyrimidine nucleotide, X and W are any nucleotide, M is any integer from 0 to 10, and N is any integer from 4 to 10. Methods of using these oligodeoxynucleotides to induce an immune response are provided.

摘要翻译： D型CpG寡脱氧核苷酸，其包含由下式表示的序列：5'X1X2X3Pu1 Py2 CpG Pu3 Py4 X4X5X6（W）M（G）N-3'其中中心CpG基序未甲基化，Pu是嘌呤核苷酸， Py是嘧啶核苷酸，X和W是任何核苷酸，M是0至10的任何整数，N是4至10的任何整数。提供使用这些寡脱氧核苷酸诱导免疫应答的方法。