公开(公告)号：US5287940A

公开(公告)日：1994-02-22

申请号：US083386

申请日：1993-06-28

申请人： Soichiro Ogawa ,  Osamu Nozaki ,  Hideaki Sakata

发明人： Soichiro Ogawa ,  Osamu Nozaki ,  Hideaki Sakata

IPC分类号： B60K11/04 ,  F16F7/108

CPC分类号： B60K11/04 ,  F16F7/108 ,  B60G2202/25

摘要： As the most important characteristic feature of the invention, in a radiator support apparatus for a vehicle, a radiator is allowed to effectively serve as a dynamic damper with respect to both a vertical flexural vibration in the back-and-forth direction of a vehicle, and a torsional vibration caused by a vibration in the widthwise direction of the vehicle. The invention relates to a radiator support apparatus for a vehicle, for mounting and supporting the lower end of a radiator on a vehicle body via mount members formed of elastic members at a plurality of support positions including two side positions in the widthwise direction of the vehicle body so as to cause the radiator to serve as a dynamic damper at the front end portion of the vehicle in a low-engine speed state, and is characterized in that the mount members located at the two side positions, in the widthwise direction of the vehicle body, of the lower end of the radiator have different spring constants.

摘要翻译： 作为本发明的最重要的特征，在车辆的散热器支撑装置中，能够使散热器相对于车辆的前后方向的垂直弯曲振动有效地用作动态阻尼器， 以及由车辆的宽度方向的振动引起的扭转振动。 本发明涉及一种用于车辆的散热器支撑装置，其用于通过在弹性构件形成的安装构件在车体上安装和支撑散热器的下端，该多个支撑位置包括在车辆的宽度方向上的两个侧面位置 使得散热器在低发动机转速状态下作为车辆前端部分的动力阻尼器，并且其特征在于，所述安装构件位于所述车辆的宽度方向的两个侧位置 车体，散热器的下端有不同的弹簧常数。

公开(公告)号：US5111774A

公开(公告)日：1992-05-12

申请号：US587842

申请日：1990-09-25

申请人： Nobuo Hiramoto ,  Seiji Nanba ,  Soichiro Ogawa ,  Osamu Nozaki

发明人： Nobuo Hiramoto ,  Seiji Nanba ,  Soichiro Ogawa ,  Osamu Nozaki

IPC分类号： F01P3/18 ,  F01P7/16 ,  F01P11/00 ,  F01P11/02 ,  F02B75/18 ,  F02B75/22

CPC分类号： F01P11/00 ,  F01P11/02 ,  F01P7/16 ,  F02B75/22 ,  F01P2060/08 ,  F01P2070/00 ,  F01P3/18 ,  F02B2075/1824

摘要： An engine cooling system includes an engine body or block having a plurality of cylinder banks, a plurality of water jackets communicated with each other for individually cooling the cylinder banks, a cooling water passage including a plurality of branch portions respectively connected to the water jackets and a joining portion convergently continued from the branch portions, and a cooling water filler provided on the joining portion at a position near one of the cylinder banks. Accordingly, the height of an engine hood of a vehicle can be effectively reduced, and in the case of filling cooling water into the filler, air in the water jackets can be smoothly expelled, thus improving water filling ability by a simple and low-cost construction.

摘要翻译： 一种发动机冷却系统，包括具有多个气缸组的发动机主体或气缸，相互连通的多个水套，用于单独冷却气缸组;冷却水通道，包括分别连接到水套的多个分支部分， 接合部分从分支部分收敛地连续，并且在靠近一个气缸组的位置处设置在接合部分上的冷却水填料。 因此，能够有效地降低车辆的发动机罩的高度，在将冷却水填充到填充物的情况下，能够平滑地排出水套中的空气，通过简单且低成本地提高灌水能力 施工。

公开(公告)号：US20080160598A1

公开(公告)日：2008-07-03

申请号：US11881428

申请日：2007-07-27

申请人： Osamu Nozaki ,  Hiroko Kawamoto ,  Motonori Munesue

发明人： Osamu Nozaki ,  Hiroko Kawamoto ,  Motonori Munesue

IPC分类号： C12M1/00

CPC分类号： G01N21/76

摘要： The present invention provides an organic monolith reactor and the preparation method thereof, wherein the reactor is possible to manufacture even into a small size and even at room temperature, and the manufacturing process is simple and relatively short period of time is required.In an organic monolith reactor according to the present invention, a horseradish peroxidase is embedded onto a microscopic area with a photopolymerized polymer. The method of preparing an organic monolith reactor according to the present invention comprises (a) dispersing a horseradish peroxidase in a mixed solution of a photopolymerizable monomer and a photopolymerizing agent, (b) introducing the dispersed solution into a microscopic area, and (c) performing a photo-irradiation onto the microscopic area at room temperature.

摘要翻译： 本发明提供一种有机整料反应器及其制备方法，其中反应器甚至可以制造成小尺寸甚至室温，制造工艺简单，需要较短的时间。 在根据本发明的有机整料反应器中，将辣根过氧化物酶用光聚合物包埋在微观区域上。 根据本发明的制备有机整料反应器的方法包括（a）将辣根过氧化物酶分散在可光聚合单体和光聚合剂的混合溶液中，（b）将分散溶液引入微观区域，和（c） 在室温下在微观区域进行光照射。

公开(公告)号：US20050250172A1

公开(公告)日：2005-11-10

申请号：US10649471

申请日：2003-08-27

申请人： Osamu Nozaki ,  Hiroko Kawamoto

发明人： Osamu Nozaki ,  Hiroko Kawamoto

IPC分类号： C12M1/40 ,  C12Q1/28 ,  G01N21/59 ,  G01N21/76

CPC分类号： G01N21/76 ,  C12Q1/28

摘要： A method for determining hydrogen peroxide and a device for use in the method excellent at determining hydrogen peroxide in body fluid in the field of a clinical examination are provided. In the method for determining hydrogen peroxide, the intensity of light emitted by reaction of immobilized horseradish peroxidase, hydrogen peroxide and imidazoles in alkaline pH is measured. The device for determining hydrogen peroxide in body fluid includes a pump for chromatography, an autosampler, a mobile phase passage, having the pump and the autosampler for body fluid, a pump for chromatography, a mobile phase passage, having the pump for a solution of imidazoles and an alkaline buffer, a flow passage, a flow cell, packed with a horseradish peroxide immobilized stationary phase, a chemiluminometer, having the flow cell, a photomultiplier, provided on the chemiluminometer in contiguity with the surface of the flow cell for the chemiluminomter. In the device, the mobile phase passages and join into the flow passage, and the flow passage is connecting to the chemiluminometer.

摘要翻译： 提供了一种用于确定过氧化氢的方法和用于在临床检查领域中测定体液中的过氧化氢的优异方法中使用的装置。 在测定过氧化氢的方法中，测定碱性pH下由固定化辣根过氧化物酶，过氧化氢和咪唑反应发出的光强度。 用于测定体液中过氧化氢的装置包括用于色谱的泵，自动进样器，流动相通道，其具有用于体液的泵和自动进样器，用于色谱的泵，流动相通道，具有用于溶液的溶液的泵 咪唑和碱性缓冲液，流通道，流通池，填充有固定有辣根过氧化物的固定相，具有流动池的化学发光计，与化学发光器的流动池的表面相邻设置在化学发光计上的光电倍增管 。 在该装置中，流动相通道并连接到流动通道中，并且流动通道连接到化学发光计。

公开(公告)号：US07288412B2

公开(公告)日：2007-10-30

申请号：US10903077

申请日：2004-07-30

申请人： Osamu Nozaki ,  Hiroko Kawamoto ,  Motonori Munesue

发明人： Osamu Nozaki ,  Hiroko Kawamoto ,  Motonori Munesue

IPC分类号： G01N33/48

CPC分类号： G01N33/80 ,  G01N27/44786

摘要： A method for determining the distribution of glycation of erythrocytic membranes includes steps of bonding magnetic beads having a boric acid group with sugars on the surfaces of erythrocytic membranes, and moving the erythrocytes bonded with the boric acid-magnetic beads under an influence of an electromagnetic force. A device for determining the distribution of glycation of erythrocytic membranes includes a container as a cell for electromagnetic-phoresis, a cathode ray and an anode ray which are connected to a direct current power supply, and a magnetic sheet which is placed outside the bottom of the container. The container has an upper surface containing a cathode hole, an anode hole, a filling hole midway between the cathode hole and the anode hole for a specimen, and an excretory hole for releasing air bubbles. After physiological saline is poured into the container, the cathode ray and the anode ray are respectively inserted into the holes to be soaked in the saline. Subsequently, a specimen of erythrocytes, which are bonded with the boric acid-magnetic beads, is infused into the container through the filling hole.

摘要翻译： 确定红细胞膜糖基化分布的方法包括将具有硼酸基团的磁珠与红细胞膜表面的糖结合的步骤，以及在电磁力的影响下移动与硼酸 - 磁珠结合的红细胞 。 用于测定红细胞膜糖化分布的装置包括：作为电磁泳用细胞的容器，与直流电源连接的阴极射线和阳极射线，以及位于 容器 容器具有包含阴极孔，阳极孔，阴极孔和用于试样的阳极孔之间的填充孔的上表面和用于释放气泡的排泄孔。 将生理盐水倒入容器后，将阴极射线和阳极射线分别插入孔中以浸泡在盐水中。 随后，与硼酸 - 磁珠结合的红细胞样品通过填充孔注入容器。

公开(公告)号：US20050026241A1

公开(公告)日：2005-02-03

申请号：US10903077

申请日：2004-07-30

申请人： Osamu Nozaki ,  Hiroko Kawamoto ,  Motonori Munesue

发明人： Osamu Nozaki ,  Hiroko Kawamoto ,  Motonori Munesue

IPC分类号： G01N33/483 ,  G01N27/00 ,  G01N27/447 ,  G01N33/53 ,  G01N33/80 ,  G01N1/30 ,  G01N33/48

CPC分类号： G01N33/80 ,  G01N27/44786

摘要： A method for determining the distribution of glycation of erythrocytic membranes includes steps of bonding magnetic beads having a boric acid group with sugars on the surfaces of erythrocytic membranes, and moving the erythrocytes bonded with the boric acid-magnetic beads under an influence of an electromagnetic force. A device for determining the distribution of glycation of erythrocytic membranes includes a container as a cell for electromagnetic-phoresis, a cathode ray and an anode ray which are connected to a direct current power supply, and a magnetic sheet which is placed outside the bottom of the container. The container has an upper surface containing a cathode hole, an anode hole, a filling hole midway between the cathode hole and the anode hole for a specimen, and an excretory hole for releasing air bubbles. After physiological saline is poured into the container, the cathode ray and the anode ray are respectively inserted into the holes to be soaked in the saline. Subsequently, a specimen of erythrocytes, which are bonded with the boric acid-magnetic beads, is infused into the container through the filling hole.

摘要翻译： 确定红细胞膜糖基化分布的方法包括将具有硼酸基团的磁珠与红细胞膜表面的糖结合的步骤，以及在电磁力的影响下移动与硼酸 - 磁性珠粒结合的红细胞 。 用于测定红细胞膜糖化分布的装置包括：作为电磁泳用细胞的容器，与直流电源连接的阴极射线和阳极射线，以及位于 容器 容器具有包含阴极孔，阳极孔，阴极孔和用于试样的阳极孔之间的填充孔的上表面和用于释放气泡的排泄孔。 将生理盐水倒入容器后，将阴极射线和阳极射线分别插入孔中以浸泡在盐水中。 随后，与硼酸 - 磁珠结合的红细胞样品通过填充孔注入容器。

公开(公告)号：US07977493B2

公开(公告)日：2011-07-12

申请号：US11494991

申请日：2006-07-28

申请人： Osamu Nozaki ,  Motonori Munesue ,  Hiroko Kawamoto

发明人： Osamu Nozaki ,  Motonori Munesue ,  Hiroko Kawamoto

IPC分类号： C07D233/70

CPC分类号： G01N33/582 ,  C07D207/444 ,  C07D473/34

摘要： Chemiluminescent substances are prepared by freezing or lyophilizing a solution of a peroxidized nitrogen-containing five-membered cyclic compound.The chemiluminescent substances have a sensitivity comparable to that of luminol chemiluminescence, are highly water-soluble, have no incorporation of impurities, are not degraded during storage, have high reproducibility in measurement results, and are very suitable for use in the detection and quantification of various substances in many applications, e.g., clinical applications.

摘要翻译： 通过将过氧化的含氮五元环化合物的溶液冷冻或冻干来制备化学发光物质。 化学发光物质具有与鲁米诺化学发光相当的灵敏度，高度水溶性，不含杂质，储存期间不降解，测量结果重现性高，非常适合用于检测和定量 许多应用中的各种物质，如临床应用。

公开(公告)号：US20080026452A1

公开(公告)日：2008-01-31

申请号：US11862232

申请日：2007-09-27

申请人： Osamu Nozaki ,  Hiroko Kawamoto ,  Motonori Munesue

发明人： Osamu Nozaki ,  Hiroko Kawamoto ,  Motonori Munesue

IPC分类号： C12M1/34

CPC分类号： G01N33/80 ,  G01N27/44786

摘要： A device for determining the distribution of glycation of erythrocytic membranes includes a container as a cell for electromagnetic-phoresis, a cathode ray and an anode ray which are connected to a direct current power supply, and a magnetic sheet which is placed outside the bottom of the container. The container has an upper surface containing a cathode hole, an anode hole, a filling hole midway between the cathode hole and the anode hole for a specimen, and an excretory hole for releasing air bubbles. After physiological saline is poured into the container, the cathode ray and the anode ray are respectively inserted into the holes to be soaked in the saline. Subsequently, a specimen of erythrocytes, which are bonded with the boric acid-magnetic beads, is infused into the container through the filling hole.

摘要翻译： 用于测定红细胞膜糖化分布的装置包括：作为电磁泳用细胞的容器，与直流电源连接的阴极射线和阳极射线，以及位于 容器 容器具有包含阴极孔，阳极孔，阴极孔和用于试样的阳极孔之间的填充孔的上表面和用于释放气泡的排泄孔。 将生理盐水倒入容器后，将阴极射线和阳极射线分别插入孔中以浸泡在盐水中。 随后，与硼酸 - 磁珠结合的红细胞样品通过填充孔注入容器。

公开(公告)号：US20070292890A1

公开(公告)日：2007-12-20

申请号：US11455474

申请日：2006-06-19

申请人： Osamu Nozaki ,  Motonori Munesue ,  Hiroko Kawamoto

发明人： Osamu Nozaki ,  Motonori Munesue ,  Hiroko Kawamoto

IPC分类号： G01N33/53 ,  C12M3/00

CPC分类号： G01N21/76 ,  G01N21/05 ,  G01N21/6428 ,  G01N2021/0346

摘要： Disclosed herein are a chemiluminescence chip, which is used to detect and quantify various kinds of materials in the case of performing the enzyme labeling of a material to be measured and performing the chemiluminescence measurement of the activity of the labeled enzyme, and a chemiluminescence detecting apparatus using the same. The chemiluminescence chip is constructed such that a filling unit, in which an immobilized enzyme is filled, is mounted in a space having an inlet port, through which a material to be measured is introduced, and an outlet port, through which the material to be measured is discharged, on a supporting structure. The chemiluminescence detecting apparatus is constructed such that the above-described chemiluminescence chip is mounted in a dark box, a cooled CCD camera is mounted above the chemiluminescence chip, an inlet pipe, which is disposed outside the dark box, is connected to the inlet port of the filling unit of the chemiluminescence chip, and an outlet pipe, which is also disposed outside the dark box, is connected to the outlet port of the filling unit.

摘要翻译： 本发明公开了一种化学发光芯片，其用于在进行待测材料的酶标记和进行化学发光测量标记酶的活性的情况下检测和定量各种材料，以及化学发光检测装置 使用相同 化学发光芯片被构造成使得其中填充有固定化酶的填充单元安装在具有入口端口的空间中，待测量材料通过该入口和出口，通过该出口 测量放电，在支撑结构上。 化学发光检测装置的结构是将上述化学发光芯片安装在暗盒中，将冷却的CCD照相机安装在化学发光芯片的上方，设置在暗箱外部的入口管连接到入口 的化学发光芯片的填充单元，并且还设置在暗箱外部的出口管连接到填充单元的出口。

公开(公告)号：US20090317511A1

公开(公告)日：2009-12-24

申请号：US12374067

申请日：2007-08-09

申请人： Shinji Kawamata ,  Eiji Emoto ,  Osamu Nozaki

发明人： Shinji Kawamata ,  Eiji Emoto ,  Osamu Nozaki

IPC分类号： A23L2/56 ,  A23L1/105 ,  A23L1/22 ,  A23L2/00 ,  C12G3/06 ,  C12C5/02

CPC分类号： C12C5/026 ,  A23L7/107 ,  A23L27/00 ,  C12G3/06

摘要： The present invention relates to a process for producing a flavor enhancer for beer and beer-like beverage and beverage of a roast material, which includes (1) heating a grinded matter of a cereal, (2) treating the grinded matter with protease, and (3) recovering an extract; and a flavor enhancer for beer and beer-like beverage and beverage of a roast material obtainable by the process. The flavor enhancer of the invention can be used for enhancing the full body and enhancement of beer and beer-like beverage and beverage of a roast material.

摘要翻译： 本发明涉及一种用于生产啤酒和饮料的饮料的啤酒和饮料的风味增强剂的制造方法，其包括（1）加热谷物的研磨物，（2）用蛋白酶处理研磨物，以及 （3）回收提取物; 以及可通过该方法获得的用于啤酒和类啤酒的饮料和饮料的风味增强剂。 本发明的风味增强剂可用于增强烘焙材料的啤酒和啤酒状饮料和饮料的全身和增强。