摘要:
The present invention relates to a color cathode ray tub e and electron gun, and more particularly, to a color cathode ray tube and electron gun to improve deflection aberration efficiently using magnetic material formed at the electron gun and to improve a resolution of a display screen.
摘要:
A biguanide derivative compound with N1-N5 substitution, which is represented by Formula 1, or a pharmaceutically acceptable salt thereof, a method of preparing the same, and a pharmaceutical composition containing the same as an active ingredient are provided. The biguanide derivative may exhibit excellent effect on activation of AMPKα and inhibition of cancer cell proliferation in a low dose, compared to conventional drugs, and thus, may be useful to treat diabetes mellitus, obesity, hyperlipidemia, hypercholesterolemia, fatty liver, coronary artery disease, osteoporosis, polycystic ovarian syndrome, metabolic syndrome, cancer, etc.
摘要:
A biguanide derivative compound with N4-N5 substitution, which is represented by Formula 1, or a pharmaceutically acceptable salt thereof, a method of preparing the same, and a pharmaceutical composition containing the same as an active ingredient are provided. The biguanide derivative may exhibit excellent effect on activation of AMPK and inhibition of cancer cell proliferation in a low dose, compared with conventional drugs, and thus, may be useful to treat diabetes mellitus, obesity, hyperlipidemia, hypercholesterolemia, fatty liver, coronary artery disease, osteoporosis, polycystic ovarian syndrome, metabolic syndrome, cancer, etc.
摘要:
Disclosed herein are a novel dicarboxylic acid salt of N,N-dimethylimidodicarbonimidic diamide, a preparation method thereof and a pharmaceutical composition comprising the same. More specifically, disclosed herein are a novel dicarboxylic acid salt of N,N-dimethylimidodicarbonimidic diamide, a crystalline acid addition salt prepared by allowing N,N-dimethylimidodicarbonimidic diamide to react with a specific dicarboxylic acid, which has improved physical and chemical properties including solubility, stability, non-hygroscopicity and anti-adhesive properties, and low toxicity, and thus is very effective in the prevention and treatment of not only diabetes and its complications in patients with so-called metabolic syndromes, in which diabetes, obesity, hyperlipidemia, fatty liver, coronary artery disease, osteoporosis, polycystic ovary syndromes, etc. appear in combination, but also p53 gene-deficient cancers, muscular pain, muscle cytotoxicity and rhabdomyolysis, as well as a preparation method thereof and a pharmaceutical composition comprising the same.
摘要:
The present invention relates to pentaerythritol derivatives represented by the following formula 1, which improve moisture retaining ability of the stratum corneum when show high moisturizing ability even in dry conditions, to a preparation method thereof, and to a liquid crystal base containing the same. (Wherein R is the same or different, saturated or unsaturated, linear or branched alkyl groups of 1 to 24 carbon atoms having hydrogen or hydroxy group or not; m and n are the same or different integers of which m is 0 to 10 and n is 1 to 10).
摘要:
An N1-cyclic amine-N5-substituted phenyl biguanide derivative of Formula 1 or a pharmaceutically acceptable salt thereof, a method of manufacturing the same, and a pharmaceutical composition including the biguanide derivative or the pharmaceutically acceptable salt thereof as an active ingredient are provided. The biguanide derivatives have an effect of inhibiting cancer cell proliferation and also exhibit anticancer activity including inhibition of cancer metastasis and cancer recurrence, because they are effective in activating AMPK, which is associated with the control of energy metabolism, even when administered in a small dose compared with conventional drugs. Also, the biguanide derivatives are highly effective at lowering blood glucose and lipid concentration by AMPK activation, thus they may be effectively used to treat diabetes mellitus, obesity, hyperlipemia, hypercholesterolemia, fatty liver, coronary artery disease, osteoporosis, polycystic ovary syndrome and metabolic syndrome.
摘要:
A page buffer circuit of a flash memory device includes a plurality of page buffers connected to a predetermined number of bit lines, respectively, and also connected to a Y-gate circuit, the page buffers perform a read operation or a program operation at the same time in response to bit line control signals, bit line select signals and control signals. Each of page buffers included in a page buffer circuit selectively gains access to one of memory cells connected to a predetermined number of bit lines, respectively. As a result, coupling capacitance component between sensing nodes can be reduced and the overall chip size can be reduced.
摘要:
Disclosed herein is RF modulator with a narrow bandpass filter. The RF modulator for modulating video and audio signals into RF signals corresponding to a frequency band of a predetermined channel includes an oscillation unit for generating a predetermined RF signal suitable for the frequency band of the predetermined channel; a mixer for modulating the video and audio signals using the RF signal generated from the oscillation unit; and a narrow bandpass filter for receiving an RF-modulated signal from the mixer, and passing only a signal of the frequency band of the predetermined channel from among the RF-modulated signal. Therefore, the RF modulator can remove or block unnecessary components such as lower side band and harmonic-frequency signals generated after video and audio signals have been RF-modulated, such that it can prevent interference between channels from being generated, resulting in the creation of more excellent video and audio signals.
摘要:
A biguanide derivative compound with N4-N5 substitution, which is represented by Formula 1, or a pharmaceutically acceptable salt thereof, a method of preparing the same, and a pharmaceutical composition containing the same as an active ingredient are provided. The biguanide derivative may exhibit excellent effect on activation of AMPK and inhibition of cancer cell proliferation in a low dose, compared with conventional drugs, and thus, may be useful to treat diabetes mellitus, obesity, hyperlipidemia, hypercholesterolemia, fatty liver, coronary artery disease, osteoporosis, polycystic ovarian syndrome, metabolic syndrome, cancer, etc.
摘要:
An N1-cyclic amine-N5-substituted phenyl biguanide derivative of Formula 1 or a pharmaceutically acceptable salt thereof, a method of manufacturing the same, and a pharmaceutical composition including the biguanide derivative or the pharmaceutically acceptable salt thereof as an active ingredient are provided. The biguanide derivatives have an effect of inhibiting cancer cell proliferation and also exhibit anticancer activity including inhibition of cancer metastasis and cancer recurrence, because they are effective in activating AMPK, which is associated with the control of energy metabolism, even when administered in a small dose compared with conventional drugs. Also, the biguanide derivatives are highly effective at lowering blood glucose and lipid concentration by AMPK activation, thus they may be effectively used to treat diabetes mellitus, obesity, hyperlipemia, hypercholesterolemia, fatty liver, coronary artery disease, osteoporosis, polycystic ovary syndrome and metabolic syndrome.