Process for preparing cycloheptene
    4.
    发明授权
    Process for preparing cycloheptene 有权
    环庚烯的制备方法

    公开(公告)号:US08993819B2

    公开(公告)日:2015-03-31

    申请号:US13545446

    申请日:2012-07-10

    Abstract: The present invention provides a process for preparing cycloheptene and derivatives thereof by ring-closing metathesis of unsymmetric 1,8-dienes whose C—C double bond at the 8 position is nonterminal. Cycloheptene and the cycloheptanone, cycloheptylamine, cycloheptanecarbaldehyde, cycloheptanecarboxylic acid and cycloheptanecarbonyl chloride conversion products thereof, and the derivatives thereof, are important synthesis units for active ingredient compounds. The ring-closing metathesis is preferably performed as a reactive distillation. The unsymmetric 1,8-dienes for the ring-closing metathesis can be obtained by catalytic decarbonylation or oxidative decarboxylation from the corresponding unsaturated carboxylic acids or carboxylic acid derivatives.

    Abstract translation: 本发明提供了一种通过非对称1,8-二烯的闭环复分解来制备环庚烯及其衍生物的方法,其中8位的C-C双键是非末端的。 环庚烯和环庚酮,环庚胺,环庚烷甲醛,环庚烷羧酸和环庚烷碳酰氯的转化产物及其衍生物是活性成分化合物的重要合成单元。 闭环复分解优选作为反应蒸馏进行。 用于闭环复分解的不对称1,8-二烯可以通过相应的不饱和羧酸或羧酸衍生物的催化脱羰或氧化脱羧获得。

    PROCESS FOR PREPARING CYCLOHEPTENE
    7.
    发明申请
    PROCESS FOR PREPARING CYCLOHEPTENE 有权
    制备环孢菌素的方法

    公开(公告)号:US20130018205A1

    公开(公告)日:2013-01-17

    申请号:US13545446

    申请日:2012-07-10

    Abstract: The present invention provides a process for preparing cycloheptene and derivatives thereof by ring-closing metathesis of unsymmetric 1,8-dienes whose C—C double bond at the 8 position is nonterminal. Cycloheptene and the cycloheptanone, cycloheptylamine, cycloheptanecarbaldehyde, cycloheptanecarboxylic acid and cycloheptanecarbonyl chloride conversion products thereof, and the derivatives thereof, are important synthesis units for active ingredient compounds. The ring-closing metathesis is preferably performed as a reactive distillation. The unsymmetric 1,8-dienes for the ring-closing metathesis can be obtained by catalytic decarbonylation or oxidative decarboxylation from the corresponding unsaturated carboxylic acids or carboxylic acid derivatives.

    Abstract translation: 本发明提供了一种通过非对称1,8-二烯的闭环复分解来制备环庚烯及其衍生物的方法,其中8位的C-C双键是非末端的。 环庚烯和环庚酮,环庚胺,环庚烷甲醛,环庚烷羧酸和环庚烷碳酰氯的转化产物及其衍生物是活性成分化合物的重要合成单元。 闭环复分解优选作为反应蒸馏进行。 用于闭环复分解的不对称1,8-二烯可以通过相应的不饱和羧酸或羧酸衍生物的催化脱羰或氧化脱羧获得。

    APPARATUS FOR CONTINUOUS SEPARATION OF MAGNETIC CONSTITUENTS AND CLEANING OF MAGNETIC FRACTION
    10.
    发明申请
    APPARATUS FOR CONTINUOUS SEPARATION OF MAGNETIC CONSTITUENTS AND CLEANING OF MAGNETIC FRACTION 有权
    用于连续分离磁性部件和磁体清洁的装置

    公开(公告)号:US20140027383A1

    公开(公告)日:2014-01-30

    申请号:US13983089

    申请日:2012-01-31

    CPC classification number: B03C1/30 B03C1/288

    Abstract: The present invention relates to an apparatus for the separation of magnetic constituents from a dispersion comprising these magnetic constituents and nonmagnetic constituents, comprising at least one loop-like canal (5) through which a dispersion flows having at least two inlets (1, 2) and at least two outlets (3, 4), further comprising at least one magnet (6) that is moveable alongside the canal (5), wherein the canal (5) is arranged relative to gravity in a way that nonmagnetic constituents are assisted to go into at least the one first outlet (3) (stream I) by sedimentation and by the current of the dispersion and magnetic constituents are forced into at least one second outlet (4) (stream II) by magnetic force against a current of flushing water. Furthermore, the present invention relates to a process for the separation of magnetic constituents from a dispersion comprising these magnetic constituents and nonmagnetic constituents.

    Abstract translation: 本发明涉及一种用于从包含这些磁性成分和非磁性成分的分散体中分离磁性成分的装置,包括至少一个环状管(5),分散体通过该管(5)至少具有两个入口(1,2) 以及至少两个出口(3,4),还包括至少一个能够沿着所述管道(5)移动的磁体(6),其中所述管道(5)以相对于重力的方式被布置成非磁性成分被辅助 通过沉降进入至少一个第一出口(3)(流I),并且通过分散的电流,通过磁力将磁性成分强制进入至少一个第二出口(4)(流II),以抵抗潮流 水。 此外,本发明涉及从包含这些磁性成分和非磁性成分的分散体中分离磁性成分的方法。

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