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公开(公告)号：US06198394B1
公开(公告)日：2001-03-06
申请号：US08760855
申请日：1996-12-05
IPC分类号： G08B2510
CPC分类号： A61B5/6831 , A61B5/0022 , A61B5/0024 , A61B5/1112 , A61B5/411 , A61B5/6805 , A61B5/681 , A61B2503/08 , A61B2503/20 , A61B2560/0242 , A61B2560/0462 , A61B2562/063 , G06F19/00
摘要： A system for remotely monitoring personnel status includes a plurality of sensors disposable on a soldier or other person for developing signals which may be used to determine the physiologicalal status. The sensors communicate with a soldier unit which can process the information to ensure that the sensor data falls within acceptable ranges and communicate with remote monitors. The soldier unit also includes a global positioning system. By using the sensor data and the global positioning system, leaders and medics can quickly and accurately track and treat casualties in battle. The system enables more rapid location of the casualty, as well as remote triage/initial diagnosis, thereby assuring that those who are most in need of treatment are attended to first. Typically, the system monitors both body surface and ambient temperature, heart rate, shivering, motion status and body condition. Additional sensors can be provided to supply information on other physiologicalal parameter which may be desired for more thorough diagnosis. The physiologicalal information may be stored and kept with the soldier to enable improved care as the soldier is moved to higher levels of care.
摘要翻译： 用于远程监控人员状态的系统包括可以用于士兵或其他人的多个传感器，用于开发可用于确定生理状态的信号。 传感器与可以处理信息的士兵单元通信，以确保传感器数据落在可接受的范围内并与远程监视器通信。 士兵部队还包括全球定位系统。 通过使用传感器数据和全球定位系统，领导和医疗人员可以快速，准确地跟踪和处理伤员的死亡。 该系统能够更快速地定位伤员，以及进行远程分诊/初步诊断，从而确保首先需要最需要治疗的人。 通常，系统监测身体表面和环境温度，心率，发抖，运动状态和身体状况。 可以提供额外的传感器来提供关于可能需要进行更彻底诊断的其它生理参数的信息。 生理信息可以与士兵一起存储和保存，以便在士兵移动到更高水平的护理时改善护理。
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公开(公告)号：US5860957A
公开(公告)日：1999-01-19
申请号：US797295
申请日：1997-02-07
IPC分类号： A61M5/142 , A61M5/20 , A61M5/24 , A61M5/28 , A61M5/30 , A61M5/31 , A61M5/315 , A61M5/32 , A61M5/34 , A61N1/30
CPC分类号： A61N1/30 , A61M5/2046 , A61M5/282 , A61M5/30 , A61M5/3232 , A61M2005/14252 , A61M2005/3022 , A61M2005/3123 , A61M2005/3128 , A61M2005/341 , A61M2205/50 , A61M2205/581 , A61M2205/583 , A61M5/14248 , A61M5/19 , A61M5/2066 , A61M5/2425 , A61M5/286 , A61M5/31568
摘要： A low-profile multipathway automatic drug delivery system utilizing a battery powered control pad coupled to a disposable drug storage and delivery system and strapped to a patient's limb or torso. A preprogrammed or on-demand drug administration sequence is input to the control pad. When a drug is to be administered, the control pad ignites a high energy density propellant charge in the drug delivery system. Expanding propellant gas exerts pressure on a drug in a second chamber and forces it from the storage reservoir. Depending upon the type of drug delivery system required for the drug being administered, the propellant will either: (i) force a hypodermic needle into a patient's muscle tissue, propel the drug in the storage container into the needle embedded in the patient, and withdraw the needle; (ii) force the drug from the storage container through a jet nozzle where the drug is injected into subcutaneous tissue; (iii) force the drug from the storage container into a patch for passive transdermal delivery; (iv) force the drug into a patch for iontophoretic transdermal diffusion; or (v) force together two drugs stored separately that are unstable when mixed, and then administer them through one of the methods described in steps (i) to (iv).
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公开(公告)号：US6165155A
公开(公告)日：2000-12-26
申请号：US232579
申请日：1999-01-16
IPC分类号： A61M5/142 , A61M5/20 , A61M5/24 , A61M5/28 , A61M5/30 , A61M5/31 , A61M5/315 , A61M5/32 , A61M5/34 , A61N1/30
CPC分类号： A61N1/30 , A61M5/14248 , A61M5/19 , A61M5/2046 , A61M5/2066 , A61M5/2425 , A61M5/282 , A61M5/286 , A61M5/30 , A61M5/31568 , A61M5/3232 , A61M2005/14252 , A61M2005/3022 , A61M2005/3123 , A61M2005/3128 , A61M2005/341 , A61M2205/50 , A61M2205/581 , A61M2205/583 , G06F19/00
摘要： A low-profile multipathway automatic drug delivery system utilizing a battery powered control pad coupled to a disposable drug storage and delivery system and strapped to a patient's limb or torso. A preprogrammed or on-demand drug administration sequence is input to the control pad. When a drug is to be administered, the control pad ignites a high energy density propellant charge in the drug delivery system. Expanding propellant gas exerts pressure on a drug in a second chamber and forces it from the storage reservoir. Depending upon the type of drug delivery system required for the drug being administered, the propellant will either: (i) force a hypodermic needle into a patient's muscle tissue, propel the drug in the storage container into the needle embedded in the patient, and withdraw the needle; (ii) force the drug from the storage container through a jet nozzle where the drug is injected into subcutaneous tissue; (iii) force the drug from the storage container into a patch for passive transdermal delivery; (iv) force the drug into a patch for iontophoretic transdermal diffusion; or (v) force together two drugs stored separately that are unstable when mixed, and then administer them through one of the methods described in steps (i) to (iv).
摘要翻译： 一种低调的多路径自动药物递送系统，其利用电池供电的控制垫，其耦合到一次性药物储存和递送系统并且绑扎到患者的肢体或躯干上。 将预编程或按需药物管理序列输入到控制垫。 当要施用药物时，控制垫点燃药物递送系统中的高能量密度推进剂装药。 扩展的推进剂气体对第二室中的药物施加压力并将其从储存容器中迫使。 取决于给药药物所需的药物递送系统的类型，推进剂将：（i）将皮下注射针刺入患者的肌肉组织，推动储存容器中的药物进入嵌入患者体内的针头，然后取出 针 （ii）将药物从储存容器中通过喷嘴喷射，药物注射到皮下组织中; （iii）将药物从储存容器中压入补片以进行被动透皮递送; （iv）强迫药物进入离子电渗透皮扩散贴片; 或（v）将混合时不稳定的两种药物分开一起，然后通过步骤（i）至（iv）中描述的方法之一进行管理。
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公开(公告)号：US20100022900A1
公开(公告)日：2010-01-28
申请号：US12348842
申请日：2009-01-05
IPC分类号： A61B5/02
CPC分类号： A61B5/05 , A61B5/02028 , A61B5/029 , A61B5/0507
摘要： A system comprising a housing containing a signal generator coupled to an antenna and a dielectric material disposed about the antenna. The device is adapted to generate and direct a plurality of signals towards the heart of the person and measure a magnitude of a signal returned from the heart. The device further comprises a processor to compare differences between a magnitude of a signal propagated and the magnitude of the signal returned off the heart and determine a signal frequency having a maximum return loss value based on those differences. The processor also estimates a change in the amplitude of motion of a portion of a wall of the heart based on the differences between the magnitude of the signal propagated by the device and the magnitude of the signal returned off of the portion of the heart.
摘要翻译： 一种系统，包括壳体，其容纳耦合到天线的信号发生器和围绕天线设置的电介质材料。 该装置适于产生并引导人的心脏的多个信号并且测量从心脏返回的信号的幅度。 该装置还包括处理器，用于比较传播的信号的幅度与从心脏返回的信号的大小之间的差异，并基于这些差异确定具有最大回波损耗值的信号频率。 处理器还基于由器件传播的信号的幅度与从心脏部分返回的信号的大小之间的差异来估计心脏壁的一部分的运动幅度的变化。
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公开(公告)号：US08721559B2
公开(公告)日：2014-05-13
申请号：US12348842
申请日：2009-01-05
CPC分类号： A61B5/05 , A61B5/02028 , A61B5/029 , A61B5/0507
摘要： A system comprising a housing containing a signal generator coupled to an antenna and a dielectric material disposed about the antenna. The device is adapted to generate and direct a plurality of signals towards the heart of the person and measure a magnitude of a signal returned from the heart. The device further comprises a processor to compare differences between a magnitude of a signal propagated and the magnitude of the signal returned off the heart and determine a signal frequency having a maximum return loss value based on those differences. The processor also estimates a change in the amplitude of motion of a portion of a wall of the heart based on the differences between the magnitude of the signal propagated by the device and the magnitude of the signal returned off of the portion of the heart.
摘要翻译： 一种系统，包括壳体，其容纳耦合到天线的信号发生器和围绕天线设置的电介质材料。 该装置适于产生并引导人的心脏的多个信号并且测量从心脏返回的信号的幅度。 该装置还包括处理器，用于比较传播的信号的幅度与从心脏返回的信号的大小之间的差异，并基于这些差异确定具有最大回波损耗值的信号频率。 处理器还基于由器件传播的信号的幅度与从心脏部分返回的信号的大小之间的差异来估计心脏壁的一部分的运动幅度的变化。
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公开(公告)号：US06160478A
公开(公告)日：2000-12-12
申请号：US179668
申请日：1998-10-27
CPC分类号： G08B25/006 , A61B5/002 , A61B5/0022 , A61B5/021 , A61B5/024 , A61B5/1117 , A61B5/6826 , A61B5/6831 , A61B5/6838 , A61B5/7465 , G06F19/00 , G06F19/3418 , G08B5/223 , G08B21/0446 , G08B21/0453 , G16H50/20 , Y10S128/903
摘要： A system for remotely monitoring a person's physical activity includes at least one accelerometer capable of measuring both the magnitude and direction of an acceleration. The acceleration data is processed to determine motion/position status and to decide whether there is a likelihood that the person has fallen, and if so, the likely direction that the person has fallen. Based on this data, the likely severity of the fall is calculated. If the severity of the fall is outside an acceptable limit, an alert state is reached upon which a signal is communicated to a remote monitoring unit. Likewise, various physiological conditions may be measured to determine the existence of any anomalous vital signs that would trigger an alarm state. If so, the remote monitoring unit will sound or otherwise communicate an alarm to a person associated with the remote monitoring unit.
摘要翻译： 用于远程监测人的身体活动的系统包括能够测量加速度的大小和方向的至少一个加速度计。 处理加速度数据以确定运动/位置状态，并确定人是否有可能下降，如果是，则该人可能的方向下降。 根据这些数据，计算出可能的跌倒严重程度。 如果跌倒的严重程度超出了可接受的极限，则达到警报状态，在该状态下将信号传达给远程监控单元。 同样地，可以测量各种生理条件以确定任何可能触发报警状态的异常生命体征的存在。 如果是这样，则远程监控单元将向与远程监视单元相关联的人发声或以其他方式传达报警。
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公开(公告)号：US20110162451A1
公开(公告)日：2011-07-07
申请号：US12116605
申请日：2008-05-07
IPC分类号： G01L5/14 , G01P15/093
CPC分类号： G01P1/127 , A42B3/046 , F41H1/02 , F41H1/04 , F41J5/056 , G01L5/0052 , G01P15/04 , G01P15/0891 , G01P15/0922
摘要： Methods and devices for a miniature, ultra-low power impact recorder for detecting, quantifying and recording the energy of an explosive blast or ballistic projectile impact. In one embodiment, the impact recorder can included a sensor comprised of an array of electromechanical resonators that is sensitive to the vibrations produced in selected, discrete frequency ranges that approximate the spectral signature characteristics of the shockwave resulting from the ballistic impact event, even after traveling through impacted material or body tissues.
摘要翻译： 用于检测，量化和记录爆炸性爆炸或弹道射弹冲击能量的微型超低功率冲击记录仪的方法和装置。 在一个实施例中，冲击记录器可以包括传感器，其包括机电谐振器的阵列，其对于在选定的离散频率范围内产生的振动敏感，所述离散频率范围近似于由弹道撞击事件引起的冲击波的频谱特征特征，即使在旅行 通过冲击材料或身体组织。
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公开(公告)号：US5236412A
公开(公告)日：1993-08-17
申请号：US627714
申请日：1990-12-14
CPC分类号： A61N1/0436 , A61N1/0448 , A61N1/044 , A61N1/0444 , A61N1/0468
摘要： A hydratable iontophoretic bioelectrode includes a plurality of layers of material capable of absorbing and holding an ionized fluid when placed in contact with the fluid. Adjacent layers are maintained at least partially out of contact from one another by disposition between the layers of spacing elements such as sugar or other dissolvable particles or cellulose. The edges of the layers may be crimped to maintain the layers in a stack for assembly with an electrode sheet; such a sheet would be provided for receiving an electrical current to thereby produce an electric field and cause a migration of ions of the ionized fluid away from the electrode sheet and into the skin or tissue of a person or animal against which the bioelectrode is placed.
摘要翻译： 可水合的离子电渗生物电极包括多个能够在与流体接触放置时吸收和保持电离流体的材料层。 相邻的层通过在诸如糖或其它可溶性颗粒或纤维素之间的间隔元件层之间的配置而至少部分地彼此不接触。 层的边缘可以被压接以将层保持在堆叠中以与电极片组装; 这样的片材将被提供用于接收电流从而产生电场并使离子化流体的离子迁移离开电极片并进入放置生物电极的人或动物的皮肤或组织。
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公开(公告)号：US6045534A
公开(公告)日：2000-04-04
申请号：US957520
申请日：1997-10-27
IPC分类号： A61M5/142 , A61M5/20 , A61M5/24 , A61M5/28 , A61M5/30 , A61M5/31 , A61M5/315 , A61M5/32 , A61M5/34 , A61N1/30 , A61M65/02
CPC分类号： A61M5/282 , A61M5/14248 , A61M5/2046 , A61M5/30 , A61M5/31591 , A61M5/3232 , A61N1/30 , A61M2005/14252 , A61M2005/206 , A61M2005/3022 , A61M2005/3123 , A61M2005/3128 , A61M2005/341 , A61M2205/50 , A61M2205/581 , A61M2205/583 , A61M5/2066 , A61M5/2425 , A61M5/2429 , A61M5/283 , A61M5/286 , A61M5/31553 , A61M5/31561 , A61M5/31568 , A61M5/31578
摘要： An automated injection module is comprised of a housing, a piston drug capsule disposed within the housing, a piston core including a puncture seal membrane defining a reservoir for holding a drug between the puncture seal membrane and the piston drug capsule, an injection device having at least one sharp end for puncturing the puncture seal upon activation of the device, an end cap on a distal end of the housing, and a pressure source on a proximal end of the housing. The pressure source is preferably a propellant that ignites and forces the piston toward the distal end. Substantially simultaneously, the injection device pierces the puncture seal membrane, the piston core is forced into the piston drug capsule, and the drug is evacuated from the reservoir through the injection device and into a patient.
摘要翻译： 一种自动注射模块包括壳体，设置在壳体内的活塞药物胶囊，活塞芯，包括限定用于在穿刺密封膜和活塞药物胶囊之间保持药物的储存器的穿刺密封膜， 至少一个尖端，用于在启动装置时刺穿穿刺密封件，在壳体的远端上的端盖以及在壳体的近端上的压力源。 压力源优选是点燃并迫使活塞朝向远端的推进剂。 基本同时，注射装置刺穿穿刺密封膜，活塞芯被迫进入活塞药物胶囊，并且药物通过注射装置从储存器排出并进入患者体内。
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10.发明授权Flow-through methods and apparatus for iontophoresis application of medicaments at a controlled pH 失效用于离子电渗疗法的流通方法和装置在受控pH下应用药物
公开(公告)号：US4886489A
公开(公告)日：1989-12-12
申请号：US64813
申请日：1987-06-19
CPC分类号： A61N1/0432 , A61N1/0448
摘要： Methods and apparatus for administering known quantities of medicaments by iontophoresis, while avoiding burns caused by extremes in the pH of the medicament medium during passage of an electric current, are disclosed. It is known that as iontophoresis progresses in conventional iontophoresis systems, the electrolysis of water occurs to produce hydrogen or hydroxyl ions at the interface of the electrode and medicament medium. Since these ions are highly mobile, they are transported directly into the skin of a patient in preference to the larger medicament ions. Thus, extreme changes in pH are experienced which result in burns due to the acidification or alkalinization of the medicament medium and passage of electric current through the skin. In addition, the efficiency of iontophoresis decreases over time. The present invention avoids extremes in pH by removing the hydrogen or hydroxyl ions which are created during iontophoresis and creates conditions for constant delivery over prolonged periods of time.In the present invention, the medicament medium adjacent the patient is periodically or constantly replaced by adding fresh medicament medium which is at the original pH. The present invention also discloses a flow-through electrode which allows new solution to constantly flow into the iontophoresis area.
摘要翻译： 公开了通过离子电渗法施用已知量的药物的方法和装置，同时避免了在电流通过过程中由药物介质的pH极端引起的烧伤。 众所周知，在常规离子电渗系统中离子电渗进行时，发生电解水以在电极和药物介质的界面产生氢或羟基离子。 由于这些离子是高度移动的，所以它们优先于较大的药物离子直接转运到患者的皮肤中。 因此，经历了pH的极端变化，其由于药物介质的酸化或碱化以及电流通过皮肤而导致燃烧。 此外，离子电渗疗法的效率随时间而降低。 本发明通过除去在离子电渗疗法期间产生的氢或羟基离子来避免pH值的极端，并且产生在长时间内恒定输送的条件。 在本发明中，通过添加处于原始pH值的新鲜药物培养基来定期或不断地替换邻近患者的药物介质。 本发明还公开了一种允许新溶液不断流入离子电渗区的流通电极。
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