-
1.发明授权Coatings for medical articles including natural biodegradable polysaccharides 失效包括天然可生物降解多糖在内的医疗用品涂料公开(公告)号：US08241655B2
公开(公告)日：2012-08-14
申请号：US11127351
申请日：2005-05-12
IPC分类号： A61K39/395 , A61F2/02
CPC分类号： A61L31/16 , A61F2210/0004 , A61F2310/00389 , A61L27/34 , A61L27/54 , A61L31/10 , A61L2300/232 , A61L2300/252 , A61L2300/258 , A61L2300/406 , A61L2300/416 , A61L2300/418 , A61L2300/622 , C08L5/00
摘要： Biodegradable coatings that include natural biodegradable polysaccharides are described. The coating is formed from a plurality of natural biodegradable polysaccharides having pendent coupling groups.
摘要翻译： 描述了包括天然可生物降解多糖的可生物降解涂层。 涂层由具有侧联偶合基团的多种天然可生物降解多糖形成。
-
2.发明授权公开(公告)号：US08512736B2
公开(公告)日：2013-08-20
申请号：US11271213
申请日：2005-11-11
CPC分类号： A61L27/20 , A61K9/0024 , A61K9/0051 , A61K9/2027 , A61K9/205 , A61K47/34 , A61L27/34 , A61L27/54 , A61L27/58 , A61L29/085 , A61L29/16 , A61L31/042 , A61L31/10 , A61L31/16 , A61L2300/232 , A61L2300/252 , A61L2300/258 , A61L2300/604 , A61L2300/606 , A61L2420/02 , B05D1/36 , B05D7/52 , C08B31/006 , C08B31/04 , C08B33/02 , C08B33/04 , C08L3/02 , C08L3/12 , C09D103/02 , C09D103/18
摘要： Biodegradable coatings and articles that include natural biodegradable polysaccharides are described. The coatings and articles are formed from a plurality of natural biodegradable polysaccharides having pendent coupling groups.
摘要翻译： 描述了包括天然可生物降解多糖的可生物降解的涂层和制品。 涂层和制品由具有悬挂偶联基团的多种天然可生物降解多糖形成。
-
公开(公告)号：US20100226960A1
公开(公告)日：2010-09-09
申请号：US11524926
申请日：2006-09-21
IPC分类号： A61F2/00 , A61K38/02 , A61K31/7088 , A61K31/715 , A61K35/12 , A61P43/00
CPC分类号： A61L27/20 , A61K9/0024 , A61K9/0051 , A61K9/2027 , A61K9/205 , A61K47/34 , A61L27/34 , A61L27/54 , A61L27/58 , A61L29/085 , A61L29/16 , A61L31/042 , A61L31/10 , A61L31/16 , A61L2300/232 , A61L2300/252 , A61L2300/258 , A61L2300/604 , A61L2300/606 , A61L2420/02 , B05D1/36 , B05D7/52 , C08B31/006 , C08B31/04 , C08B33/02 , C08B33/04 , C08L3/02 , C08L3/12 , C09D103/02 , C09D103/18
摘要： Matrices formed from a natural biodegradable material and that exhibit surface degradation in the presence of an enzyme are described. Matrices including a bioactive agent can be implanted or formed in a subject for release of the bioactive agent upon degradation of the matrix. The matrix can be provided in various forms, including coatings for implantable devices, implants, and in-situ formed matrices. The matrix can also be in the form of a medical device having a structure that is used to treat a medical condition.
摘要翻译： 描述了由天然可生物降解材料形成的并且在酶存在下显示表面降解的基质。 包括生物活性剂的基质可以在受试者中植入或形成，以在基质降解时释放生物活性剂。 基质可以以各种形式提供，包括用于可植入装置的涂层，植入物和原位形成的基质。 该基质还可以是具有用于治疗医疗状况的结构的医疗装置的形式。
-
4.发明授权公开(公告)号：US08241656B2
公开(公告)日：2012-08-14
申请号：US11271237
申请日：2005-11-11
IPC分类号： A61K39/395 , A61F2/02
CPC分类号： A61L27/20 , A61K9/0024 , A61K9/0051 , A61K9/2027 , A61K9/205 , A61K47/34 , A61L27/34 , A61L27/54 , A61L27/58 , A61L29/085 , A61L29/16 , A61L31/042 , A61L31/10 , A61L31/16 , A61L2300/232 , A61L2300/252 , A61L2300/258 , A61L2300/604 , A61L2300/606 , A61L2420/02 , B05D1/36 , B05D7/52 , C08B31/006 , C08B31/04 , C08B33/02 , C08B33/04 , C08L3/02 , C08L3/12 , C09D103/02 , C09D103/18
摘要： Medical articles having a body member including natural biodegradable polysaccharides are described. The body member is formed from a plurality of natural biodegradable polysaccharides having pendent coupling groups. The body member can also include a bioactive agent which can be released to provide a therapeutic effect to a patient.
摘要翻译： 描述具有包括天然可生物降解多糖的主体成分的医疗制品。 身体构件由多个具有侧联偶联基团的天然可生物降解多糖形成。 身体构件还可以包括可以释放以向患者提供治疗效果的生物活性剂。
-
5.发明申请Latent stabilization of bioactive agents releasable from implantable medical articles 审中-公开从植入式医疗制品中释放的生物活性剂的潜在稳定性公开(公告)号：US20080154241A1
公开(公告)日：2008-06-26
申请号：US12001009
申请日：2007-12-07
IPC分类号： A61K9/22
CPC分类号： A61L27/54 , A61L27/34 , A61L27/505 , A61L27/58 , A61L2300/256 , A61L2300/414 , A61L2300/426 , A61L2300/604
摘要： Implantable medical articles comprising natural biodegradable polysaccharides are described. The polysaccharides can provide desirable release properties, and can also be degraded into products that can act as an excipient in the presence of the bioactive agent. In some aspects, the articles are ocular implants formed of a matrix of natural biodegradable polysaccharides. These ocular implants include a bioactive agent that can be released within the eye to treat an ocular condition or indication.
摘要翻译： 描述了包含天然可生物降解多糖的可植入医疗制品。 多糖可以提供期望的释放性质，并且还可以降解成可在生物活性剂存在下作为赋形剂的产物。 在一些方面，所述制品是由天然可生物降解的多糖基质形成的眼部植入物。 这些眼部植入物包括可以在眼睛内释放以治疗眼睛状况或指征的生物活性剂。
-
公开(公告)号：US07968614B2
公开(公告)日：2011-06-28
申请号：US11453494
申请日：2006-06-15
CPC分类号： A61K6/0017 , A61K6/0023 , A61K6/0052 , A61K6/0091 , A61K6/097 , C08L39/06 , C08L1/00 , C08L23/00 , C08L29/04 , C08L33/26 , C08L3/00
摘要： The invention provides compositions that include macromers and visible light-activated polymerization initiators, and methods for forming a matrix using these compositions in conjunction with a light source that emits light primarily in the visible light spectrum.
摘要翻译： 本发明提供包括大分子单体和可见光活化聚合引发剂的组合物，以及使用这些组合物与主要在可见光谱发射光的光源一起形成基质的方法。
-
7.发明申请Polypeptide microparticles having sustained release characteristics, methods and uses 审中-公开具有持续释放特性，方法和用途的多肽微粒公开(公告)号：US20090022805A1
公开(公告)日：2009-01-22
申请号：US12215508
申请日：2008-06-27
申请人： Joram Slager , Michael D. New , John V. Wall , Michael J. Burkstrand , Stephen J. Chudzik , Pamela J. Reed
发明人： Joram Slager , Michael D. New , John V. Wall , Michael J. Burkstrand , Stephen J. Chudzik , Pamela J. Reed
CPC分类号： A61K9/5036 , C07K16/42 , C07K2317/55
摘要： The invention provides polypeptide microparticles having control release features, particular methods for the preparation of such microparticles, and drug delivery systems that include polypeptide microparticles.
摘要翻译： 本发明提供了具有控制释放特征的多肽微粒，用于制备这种微粒的具体方法以及包括多肽微粒的药物递送系统。
-
8.发明申请公开(公告)号：US20120100187A1
公开(公告)日：2012-04-26
申请号：US13281802
申请日：2011-10-26
IPC分类号： A61K9/00 , A61K31/7052 , B05D5/00 , A61K38/02
摘要： Embodiments of the invention include multi-layer coatings and methods for controlling the elution of hydrophilic active agents. In an embodiment, the invention includes a medical device including a substrate, a primer polymer layer disposed on the substrate, an expandable layer disposed on the primer polymer layer, and a hydrophilic active agent dispersed within the expandable layer. In an embodiment, the invention includes a method of forming a medical device including depositing a primer layer onto a substrate, the primer layer comprising a primer polymer. The method can further include depositing an expandable layer onto the primer layer, the expandable layer including an expandable polymer, and a hydrophilic active agent. The expandable layer can be deposited with a solvent that is effective to solvate both the expandable polymer and the primer polymer. Other embodiments are also included herein.
摘要翻译： 本发明的实施方案包括多层涂层和控制亲水性活性剂洗脱的方法。 在一个实施方案中，本发明包括医疗装置，其包括基材，设置在基材上的底漆聚合物层，设置在底漆聚合物层上的可膨胀层，以及分散在可膨胀层内的亲水性活性剂。 在一个实施方案中，本发明包括形成医疗装置的方法，包括将底漆层沉积在基底上，底层包含底漆聚合物。 该方法还可以包括将可膨胀层沉积到底漆层上，该可膨胀层包括可膨胀聚合物和亲水性活性剂。 可膨胀层可以用有效溶剂化可发性聚合物和底漆聚合物的溶剂沉积。 本文还包括其它实施例。
-
-
-
-
-
-
-
搜索结果
8 条记录 (耗时 0.041 秒)
