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20 条记录 (耗时 0.021 秒)

    Expandable guide sheath and apparatus and methods for making them
    1.
    发明申请
    Expandable guide sheath and apparatus and methods for making them 有权
    可扩展导套及其制造方法

    公开(公告)号：US20050149104A1

    公开(公告)日：2005-07-07

    申请号：US10958034

    申请日：2004-10-04

    申请人： Stephen Leeflang ,  Christine Ventura ,  Christian Eversull ,  Nicholas Mourlas ,  Christopher Loew

    发明人： Stephen Leeflang ,  Christine Ventura ,  Christian Eversull ,  Nicholas Mourlas ,  Christopher Loew

    IPC分类号： A61F2/958 ,  A61B17/22 ,  A61B17/34 ,  A61M25/00 ,  A61M25/06 ,  A61M29/00 ,  A61N1/05

    CPC分类号： A61M25/0662 ,  A61B17/3439 ,  A61M25/003 ,  A61M2025/0024 ,  A61M2025/0035 ,  A61N1/056

    摘要： Apparatus and methods are provided for providing access to a body lumen. The apparatus includes a tubular member including a proximal end, a distal end sized for insertion into a body lumen, and a lumen extending between the proximal and distal ends. A pushable stiffening member extends from the distal end of the tubular member, the elongate member terminating in a distal tip. An expandable sheath extends along at least a portion of the stiffening member, the sheath being expandable from a contracted condition to minimize a profile of the sheath to allow insertion along with the stiffening member into a body lumen, and an enlarged condition wherein the sheath at least partially defines a lumen communicating with the tubular member lumen. In one embodiment, the sheath includes an outer lumen and an inner lumen floating within the outer lumen, and the stiffening member is carried in the inner lumen.

    摘要翻译： 提供了用于提供对体腔的接近的装置和方法。 该装置包括管状构件，其包括近端，尺寸适于插入体腔的远端以及在近端和远端之间延伸的内腔。 可推动加强构件从管状构件的远端延伸，细长构件终止于远端。 可扩张护套沿着加强构件的至少一部分延伸，护套可以从收缩状态扩展，以最小化护套的轮廓，以允许将加强构件插入体腔内，并且扩大状态，其中护套 至少部分地限定与所述管状构件内腔连通的管腔。 在一个实施例中，护套包括外腔和漂浮在外腔内的内腔，并且加强构件承载在内腔中。

    SLITTABLE OR REMOVABLE VALVES AND APPARATUS AND METHODS FOR MAKING AND USING THEM
    3.
    发明申请
    SLITTABLE OR REMOVABLE VALVES AND APPARATUS AND METHODS FOR MAKING AND USING THEM 有权
    可变的或可拆卸的阀门，以及用于制造和使用它们的装置和方法

    公开(公告)号：US20070293845A1

    公开(公告)日：2007-12-20

    申请号：US11687653

    申请日：2007-03-18

    申请人： Stephen Leeflang ,  Christine Ventura ,  Christian Eversull ,  Nicholas Mourlas

    发明人： Stephen Leeflang ,  Christine Ventura ,  Christian Eversull ,  Nicholas Mourlas

    IPC分类号： A61M25/00

    CPC分类号： A61M39/22 ,  A61M25/0668 ,  A61M39/06 ,  A61M39/0606

    摘要： Valves for medical devices and methods for making them are provided. In one embodiment, a valve is injection molded as a single piece that includes a tubular body and a flap. The tubular body includes an open first end, a closed second end, and a passage extending between the first and second ends defining a central longitudinal axis. The second end includes an end wall including a hole therein communicating with the passage. The flap is formed in the end wall over the hole and is movable away from the second end when an elongate device is introduced through the passage and the hole. Apparatus are also provided for delivering a medical device into a patient's body that includes an elongate tubular member including proximal and distal ends, a lumen extending between the proximal and distal ends; and a valve attached to the proximal end.

    摘要翻译： 提供用于医疗设备的阀门及其制造方法。 在一个实施例中，阀被注塑成单件，其包括管状主体和折翼。 管状体包括敞开的第一端，闭合的第二端和在第一和第二端之间延伸的通道，限定中心纵向轴线。 第二端包括端壁，其包括与通道连通的孔。 翼片形成在洞上方的端壁中，并且当细长装置通过通道和孔引入时，翼片可移动离开第二端。 还提供了用于将医疗装置输送到患者体内的装置，其包括细长管状构件，其包括近端和远端，在近端和远端之间延伸的内腔; 以及附接到近端的阀。

    Slittable and Peelable Sheaths and Methods for Making and Using Them
    4.
    发明申请
    Slittable and Peelable Sheaths and Methods for Making and Using Them 有权
    可剥离和剥皮的护套及其制造和使用方法

    公开(公告)号：US20070167930A1

    公开(公告)日：2007-07-19

    申请号：US11563142

    申请日：2006-11-24

    申请人： Christian Eversull ,  Stephen Leeflang ,  Nicholas Mourlas

    发明人： Christian Eversull ,  Stephen Leeflang ,  Nicholas Mourlas

    IPC分类号： A61M25/00

    CPC分类号： A61M25/0668 ,  A61M25/0045 ,  A61M25/005

    摘要： Splittable tubular devices and methods for making them are provided. In one embodiment, a tubular device includes a proximal end, a distal end sized for introduction into a body lumen, and a lumen extending between the proximal and distal ends. The tubular device includes an outer tubular layer defining a circumference; and a reinforcing layer bonded to the outer tubular layer, the reinforcing layer including a circumferential interruption. To make a tubular device, an elongate tubular reinforcing structure may be folded into itself to define first and second longitudinal edges, and rolled until the longitudinal edges are disposed adjacent one another. The reinforcing structure may be attached to a tubular structure such that the longitudinal edges define a circumferential interruption extending along a length of the tubular structure.

    摘要翻译： 提供可分离的管状装置及其制造方法。 在一个实施例中，管状装置包括近端，尺寸适于引入体腔的远端和在近端和远端之间延伸的内腔。 管状装置包括限定圆周的外管层; 以及加强层，其与所述外管层接合，所述加强层包括周向中断。 为了制造管状装置，细长管状加强结构可以折叠成自身以限定第一和第二纵向边缘，并且滚动直到纵向边缘彼此相邻地设置。 加强结构可以附接到管状结构，使得纵向边缘限定沿着管状结构的长度延伸的圆周中断。

    APPARATUS AND METHODS FOR DELIVERING STEM CELLS AND OTHER AGENTS INTO CARDIAC TISSUE
    5.
    发明申请
    APPARATUS AND METHODS FOR DELIVERING STEM CELLS AND OTHER AGENTS INTO CARDIAC TISSUE 有权
    将干细胞和其他药物递送到心脏组织的装置和方法

    公开(公告)号：US20070083187A1

    公开(公告)日：2007-04-12

    申请号：US11465109

    申请日：2006-08-16

    申请人： Christian Eversull ,  Stephen Leeflang ,  Christine Ventura ,  Nicholas Mourlas

    发明人： Christian Eversull ,  Stephen Leeflang ,  Christine Ventura ,  Nicholas Mourlas

    IPC分类号： A61M31/00 ,  A61M25/00 ,  A61M5/00

    CPC分类号： A61M25/10 ,  A61M2025/105 ,  A61M2025/1052

    摘要： Apparatus, systems, and methods are provided for delivering stem cells or other agents to cardiac tissue surrounding a cardiac vessel or to tissue adjacent other body lumens. The apparatus includes an expandable member and a source of one or more agents communicating with a lumen extending between proximal and distal ends of the apparatus. The distal end of the apparatus is advanced through one or more body lumens until the distal end is disposed within or adjacent the target body lumen. The target body lumen is sealed, e.g., by expanding the expandable member, thereby isolating the target body lumen. One or more agents are delivered into the target body lumen with sufficient pressure to extravasate the one or more agents into tissue surrounding the target body lumen.

    摘要翻译： 提供了装置，系统和方法，用于将干细胞或其它药剂递送到围绕心脏血管的心脏组织或邻近其他体腔的组织。 该装置包括可扩张构件和一个或多个试剂的源，其与在装置的近端和远端之间延伸的内腔连通。 装置的远端通过一个或多个体腔前进直到远端设置在目标体腔内或邻近靶体腔。 目标体腔被密封，例如通过膨胀可扩张构件，从而隔离目标体腔。 一个或多个药剂以足够的压力被递送到目标体腔内，以将一种或多种药剂外渗到靶体周围的组织中。

    Variable steerable catheters and methods for using them
    8.
    发明申请
    Variable steerable catheters and methods for using them 审中-公开
    可变导向导管及其使用方法

    公开(公告)号：US20050197623A1

    公开(公告)日：2005-09-08

    申请号：US11062074

    申请日：2005-02-17

    申请人： Stephen Leeflang ,  Trevor Lofthouse ,  George Morrison ,  Nicholas Mourlas ,  Christian Eversull

    发明人： Stephen Leeflang ,  Trevor Lofthouse ,  George Morrison ,  Nicholas Mourlas ,  Christian Eversull

    IPC分类号： A61M29/00 ,  A61M31/00 ,  A61M37/00

    CPC分类号： A61B1/00078 ,  A61B1/00082 ,  A61B1/0055 ,  A61B1/018 ,  A61M25/0136 ,  A61M25/0144 ,  A61M25/104 ,  A61M2025/0024 ,  A61M2025/0681

    摘要： An apparatus for accessing a body lumen includes a tubular member including a proximal end, a distal end sized for introduction into a body lumen, and a passage extending along a steerable distal portion of the tubular member. The passage includes a first region extending substantially parallel to a center of modulus of the distal portion and a second region offset from the center of modulus. A steering element is disposed through the passage extending along the distal portion that includes a proximal end disposed adjacent the tubular member proximal end, and a distal end fixed to the tubular member distal end beyond the distal portion. A steering adjustment member is slidable within the passage for selectively directing a portion of the steering element between the first and second regions to vary the steerability of the distal portion.

    摘要翻译： 用于进入体腔的装置包括管状构件，其包括近端，尺寸适于引入体腔的远端以及沿管状构件的可操纵的远端部分延伸的通道。 通道包括基本上平行于远侧部分的模量中心延伸的第一区域和从模数中心偏移的第二区域。 转向元件设置成穿过沿着远侧部分延伸的通道，该通道包括邻近管状构件近端设置的近端，以及固定到管状构件远端超过远端部分的远端。 转向调节构件可在通道内滑动，用于选择性地将转向元件的一部分引导到第一和第二区域之间，以改变远端部分的可操纵性。

    Complex Shaped Steerable Catheters and Methods for Making and Using Them
    10.
    发明申请
    Complex Shaped Steerable Catheters and Methods for Making and Using Them 审中-公开
    复杂的导向导管及其制造和使用方法

    公开(公告)号：US20070016130A1

    公开(公告)日：2007-01-18

    申请号：US11382026

    申请日：2006-05-06

    申请人： Stephen Leeflang ,  George Morrison ,  Nicholas Mourlas ,  Christian Eversull

    发明人： Stephen Leeflang ,  George Morrison ,  Nicholas Mourlas ,  Christian Eversull

    IPC分类号： A61M31/00 ,  A61B1/06

    CPC分类号： A61M25/0105 ,  A61B1/00165 ,  A61M25/0023 ,  A61M25/0032 ,  A61M25/005 ,  A61M25/0147 ,  A61M25/10 ,  A61M2025/0036 ,  A61M2025/0161

    摘要： Apparatus and methods are provided for accessing a body lumen within a patient's body. Generally, the apparatus includes a tubular member including proximal and distal ends, a steering element extending between the proximal and distal ends, and an actuator for directing the distal end between a relaxed configuration and a complex curved configuration. In the relaxed configuration, the distal end may assume a straight or curved shape. In the complex curved configuration, the distal end may assume a curvilinear shape. In one embodiment, the complex curved configuration may include a first curved portion defining an arc within a plane, and a second portion that extends out of the plane. An embodiment with a left hand rule configuration may be introduced into the right atrium of a heart from a superior approach, and the complex curved configuration may facilitate accessing the coronary sinus.

    摘要翻译： 提供了用于访问患者身体内的体腔的装置和方法。 通常，该装置包括管状构件，其包括近端和远端，在近端和远端之间延伸的操纵元件和用于将远端引导在松弛构型和复合弯曲构型之间的致动器。 在松弛构造中，远端可呈直线或弯曲形状。 在复杂的弯曲构型中，远端可呈现曲线形状。 在一个实施例中，复合弯曲构造可以包括在平面内限定弧的第一弯曲部分和延伸出平面的第二部分。 具有左手规则配置的实施例可以从优越的方法引入心脏的右心房，并且复曲线配置可以有助于进入冠状窦。