公开(公告)号：US20050184815A1

公开(公告)日：2005-08-25

申请号：US11030009

申请日：2005-01-05

申请人： Steven Lipp ,  Joseph Abeles ,  Alan Braun ,  Sterling McBride ,  John Riganati ,  Ralph Whaley ,  Peter Zanzucchi

发明人： Steven Lipp ,  Joseph Abeles ,  Alan Braun ,  Sterling McBride ,  John Riganati ,  Ralph Whaley ,  Peter Zanzucchi

IPC分类号： H01J25/50

CPC分类号： G04F5/14

摘要： A cell suitable for use with an atomic clock and a method for making the same, the cell including: a silicon wafer having a recess formed therein; at least one amorphous silicate member having an ion mobility and temperature expansion coefficient approximately that of silicon sealing the recess; and, an alkali metal containing component and buffer gas contained in the recess. The method includes: providing a silicon wafer; forming a cavity through the silicon wafer; introducing an alkali metal containing component and buffer gas into the cavity; and, anodically bonding at least one amorphous silicate member having an ion mobility and temperature expansion coefficient approximately that of silicon to the wafer to close the cavity.

摘要翻译： 适用于原子钟的电池及其制造方法，所述电池包括：形成有凹部的硅晶片; 至少一种无定形硅酸盐部件，其离子迁移率和温度膨胀系数近似于密封凹部的硅的非晶硅酸盐部件; 以及包含在所述凹部中的含碱金属成分和缓冲气体。 该方法包括：提供硅晶片; 通过硅晶片形成空腔; 将含碱金属的组分和缓冲气体引入所述空腔中; 并且将具有大约硅的离子迁移率和温度膨胀系数的至少一种无定形硅酸盐构件阳极结合到晶片上以封闭空腔。

公开(公告)号：US20050070819A1

公开(公告)日：2005-03-31

申请号：US10401683

申请日：2003-03-31

申请人： Christopher Poux ,  Gary Fletcher ,  Sterling McBride ,  John Margicin ,  Peter Zanzucchi ,  John Aceti ,  Syrous Parsay ,  Derek Mahoney

发明人： Christopher Poux ,  Gary Fletcher ,  Sterling McBride ,  John Margicin ,  Peter Zanzucchi ,  John Aceti ,  Syrous Parsay ,  Derek Mahoney

IPC分类号： A61B5/00 ,  A61B5/15 ,  A61M20060101 ,  B65D81/00

CPC分类号： A61B5/15016 ,  A61B5/150022 ,  A61B5/150099 ,  A61B5/150114 ,  A61B5/150122 ,  A61B5/150145 ,  A61B5/150167 ,  A61B5/15019 ,  A61B5/150221 ,  A61B5/150396 ,  A61B5/150511 ,  A61B5/150954 ,  A61B5/1519

摘要： A device operable to extract a sample of body fluid, the device including at least one skin-penetration member, an actuator, a controller, and a housing mounting the at least one skin-penetration member for extension from the device. Another device for extracting body fluid includes at least one skin-penetration member having an inner bore and an outer diameter, and at least one axially moveable hollow tubular member disposed in the inner bore. Yet another device includes at least one skin-penetration member, an actuator, a controller, a housing mounting the at least one skin-penetration member, and a skin sensor measuring electrical parameters transmitted through the at least one skin-penetration member. Associated methods are also disclosed.

摘要翻译： 一种可操作以提取体液样品的装置，所述装置包括至少一个皮肤穿透构件，致动器，控制器和壳体，其安装所述至少一个皮肤穿透构件用于从装置延伸。 用于提取体液的另一装置包括至少一个具有内孔和外径的皮肤穿透构件，以及设置在内孔中的至少一个可轴向移动的中空管状构件。 另一装置包括至少一个皮肤穿透构件，致动器，控制器，安装至少一个皮肤穿透构件的壳体，以及测量通过至少一个皮肤穿透构件传输的电参数的皮肤传感器。 还公开了相关方法。

公开(公告)号：US20060094985A1

公开(公告)日：2006-05-04

申请号：US11311667

申请日：2005-12-20

申请人： John Aceti ,  Sterling McBride ,  Richard Moroney ,  Christopher Gregory ,  Peter Zanzucchi

发明人： John Aceti ,  Sterling McBride ,  Richard Moroney ,  Christopher Gregory ,  Peter Zanzucchi

IPC分类号： A61F7/12 ,  A61M5/20 ,  A61M5/32 ,  A61B5/00 ,  B65D81/00

CPC分类号： A61B5/150984 ,  A61B5/1411 ,  A61B5/14514 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/150022 ,  A61B5/150076 ,  A61B5/150213 ,  A61B5/150389 ,  A61B5/150503 ,  A61B5/150526 ,  A61B5/150755 ,  A61B5/15087 ,  A61B5/150969 ,  A61B5/15109 ,  A61B5/15119 ,  A61B5/15123 ,  A61B5/15146 ,  A61B5/15153 ,  A61B5/15163 ,  A61B5/155 ,  A61B5/157 ,  A61B5/681 ,  A61B5/6833 ,  A61B2560/0412 ,  A61B2560/0443 ,  A61M37/0015 ,  A61M2037/0023 ,  A61M2037/0038 ,  A61M2209/088 ,  A61M2230/201 ,  G01N33/491

摘要： The invention relates to analyte monitoring/drug (pharmaceutical agent) delivery device. The invention is suited for monitoring various blood constituents such as glucose. The device has a housing that at least partially encloses a plurality of microneedles disposed on a carrier and an electronics portion. Each microneedle is in fluid communication with a corresponding microchannel. Each microneedle is individually addressable. That is, each microneedle can be extended and retracted individually via an actuator. The electronics portion includes a processor and associated circuitry (e.g., memory, supporting electronics and the like), a motor or the like, a sensor, a power supply (e.g., battery) and optionally an interface. In general, the processor controls the operation of the device and is data communication with the actuator, motor, sensor and interface. The invention provides for autonomous operation, that is, without intervention of the user. The invention can optionally provide for calibration without intervention of the user. The invention can also provide for semi-continuous monitoring for day and night time. The invention can provide for up to four, or more, weeks of operation. The invention can provide for a device that is relative small in size, and therefore unobtrusive. The invention can also provide for device with remote control and interactive electronics. The invention may be also used for the delivery of various pharmaceutical agents including high potency drugs to minimize patient intervention and minimize discomfort.

公开(公告)号：US20050202567A1

公开(公告)日：2005-09-15

申请号：US11125107

申请日：2005-05-10

申请人： Peter Zanzucchi ,  Sterling McBride ,  Alexei Tsekoun

发明人： Peter Zanzucchi ,  Sterling McBride ,  Alexei Tsekoun

IPC分类号： A61B5/00 ,  G01N21/03 ,  G01N21/35 ,  G01N21/77 ,  G01N21/78 ,  G01N21/86 ,  G01N33/543 ,  G01N33/00

CPC分类号： A61B5/1459 ,  A61B5/1411 ,  A61B5/14514 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/150022 ,  A61B5/150213 ,  A61B5/150358 ,  A61B5/150389 ,  A61B5/150503 ,  A61B5/150755 ,  A61B5/151 ,  A61B5/157 ,  G01N21/03 ,  G01N21/359 ,  G01N21/7703 ,  G01N21/78 ,  G01N21/8483 ,  G01N33/54373 ,  G01N2021/0325 ,  G01N2021/0346 ,  Y10T436/144444

摘要： Arrangements for the detection of the presence and/or concentration of an analyte in a sample of bodily fluid include diffuse transmission, diffuse reflection and edge or waveguide illumination arrangements. A vertical flow assay arrangement and/or technique is also disclosed, and includes a detection component that can be in the form of an array of optical detection elements. A number of assay pad constructions are described which may include at least one or more of the following components: a prefilter component, a reflective component, a membrane component, a reagent component, a mesh component, and a component to prevent lateral spreading.

摘要翻译： 用于检测体液样品中分析物的存在和/或浓度的布置包括漫射透射，漫反射和边缘或波导照明装置。 还公开了垂直流动测定装置和/或技术，并且包括可以是光学检测元件阵列形式的检测部件。 描述了可以包括以下组件中的至少一个或多个的多个测定垫构造：预滤器组件，反射组件，膜组分，试剂组分，网孔组分和防止侧向扩展的组分。

公开(公告)号：US20100026394A1

公开(公告)日：2010-02-04

申请号：US12487400

申请日：2009-06-18

申请人： Timothy Davis ,  Sterling McBride ,  Alan Braun ,  William Happer

发明人： Timothy Davis ,  Sterling McBride ,  Alan Braun ,  William Happer

IPC分类号： H03L7/26

CPC分类号： H03L7/26 ,  G04F5/14

摘要： The present invention provides a system and method for achieving a calibration-free primary atomic clock standard operating at the 0-0 transition free-atom frequency, thus creating a primary frequency standard, with attributes that include scalable to chip-scale dimensions and power consumption.

摘要翻译： 本发明提供一种用于实现在0-0跃迁自由原子频率下操作的无校准原子钟表标准的系统和方法，从而产生主频率标准，其属性包括可扩展到芯片尺寸尺寸和功耗 。

公开(公告)号：US07902927B2

公开(公告)日：2011-03-08

申请号：US12487400

申请日：2009-06-18

申请人： Timothy Davis ,  Sterling McBride ,  Alan Braun ,  William Happer

发明人： Timothy Davis ,  Sterling McBride ,  Alan Braun ,  William Happer

IPC分类号： H03L7/26 ,  H03L1/02 ,  H03B17/00

CPC分类号： H03L7/26 ,  G04F5/14

摘要： The present invention provides a system and method for achieving a calibration-free primary atomic clock standard operating at the 0-0 transition free-atom frequency, thus creating a primary frequency standard, with attributes that include scalable to chip-scale dimensions and power consumption.

摘要翻译： 本发明提供一种用于实现在0-0跃迁自由原子频率下操作的无校准原子钟表标准的系统和方法，从而产生主频率标准，其属性包括可扩展到芯片尺寸尺寸和功耗 。

公开(公告)号：US20060267023A1

公开(公告)日：2006-11-30

申请号：US11433930

申请日：2006-05-15

申请人： Sterling McBride

发明人： Sterling McBride

IPC分类号： H01L31/0312

CPC分类号： B81C3/001 ,  B81C2203/031 ,  C03C27/00

摘要： The present invention discloses an anodically bonded vacuum cell structure with a glass substrate including a cavity, and a substrate deposited on the glass substrate, thereby enclosing the cavity to form a bonding interface. The bonding interface having silicon such that the substrate includes a layer of silicon or a secondary substrate with silicon layer bonded onto the secondary substrate.

摘要翻译： 本发明公开了一种阳极结合的真空电池结构，其具有包括空腔的玻璃基板和沉积在玻璃基板上的基板，由此封闭空腔以形成接合界面。 所述接合界面具有硅，使得所述衬底包括硅层或具有硅层结合到所述次级衬底上的次级衬底。