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公开(公告)号：US5685839A
公开(公告)日：1997-11-11
申请号：US439191
申请日：1995-05-11
IPC分类号： A61B10/00 , A61B10/02 , A61B10/06 , A61B17/00 , A61B17/22 , A61B17/24 , A61B17/28 , A61B17/34 , A61B18/00 , A61B18/08 , A61B18/14 , A61B18/18 , A61B18/22 , A61B18/24 , A61B19/00 , A61F7/00 , A61M1/00 , A61M3/02 , A61M25/00 , A61N1/06 , A61N1/40 , A61N5/02 , A61N5/04
CPC分类号： A61B10/0233 , A61B10/0275 , A61B10/06 , A61B18/00 , A61B18/1477 , A61B18/1482 , A61B18/1485 , A61B18/18 , A61B18/1815 , A61B18/24 , A61N1/06 , A61N1/40 , A61N1/403 , A61N5/02 , A61N5/045 , A61B10/0241 , A61B18/082 , A61B18/1206 , A61B18/14 , A61B18/1402 , A61B18/1442 , A61B18/148 , A61B2017/00084 , A61B2017/00092 , A61B2017/00101 , A61B2017/00106 , A61B2017/00123 , A61B2017/00181 , A61B2017/00194 , A61B2017/00274 , A61B2017/00292 , A61B2017/003 , A61B2017/00867 , A61B2017/22038 , A61B2017/22072 , A61B2017/22077 , A61B2017/22082 , A61B2017/248 , A61B2017/2939 , A61B2017/3488 , A61B2018/00005 , A61B2018/00011 , A61B2018/00041 , A61B2018/00083 , A61B2018/00095 , A61B2018/00101 , A61B2018/00196 , A61B2018/0022 , A61B2018/00547 , A61B2018/00577 , A61B2018/00678 , A61B2018/00702 , A61B2018/00726 , A61B2018/00744 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00886 , A61B2018/0091 , A61B2018/00916 , A61B2018/00946 , A61B2018/0097 , A61B2018/00982 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/128 , A61B2018/1425 , A61B2018/1861 , A61B2018/2238 , A61B2090/0814 , A61B2090/3614 , A61B2090/378 , A61B2090/3782 , A61B2090/3786 , A61B2090/3925 , A61B2217/005 , A61B2217/007 , A61F2007/0054 , A61M2025/0086 , A61M2025/0087 , A61M2025/0089 , A61M2025/0096 , A61M2025/018 , A61M25/0068 , A61M3/0279 , A61N5/04
摘要： A medical probe apparatus comprising a catheter having a stylet guide housing with one or more stylet ports therein and stylet guides for directing one or more flexible stylets outward through respective stylet ports and through intervening tissue to target tissue. The active stylets emit radio frequency RF energy which establishes an RF current in the patient. The current, being densest at the stylet tips, causes heating of the surrounding tissue to initiate ablation of the target tissue. One aspect of the invention includes temperature sensing stylets at the location of the RF emitting stylets to monitor the temperature of the tissue being ablated. This allows the surgeon to have increased knowledge about the abating action under way in order to control the intensity of the applied RF current, or to adjust the amount of time the current is applied, or both. Further included herein is a plurality of temperature sensors mounted on an ultrasound probe to be used to monitor tissue temperature at the ultrasound probe while allowing the ultrasound device to monitor the position and orientation of the medical probe apparatus of the present invention.
摘要翻译： 一种医疗探针装置，包括具有其中具有一个或多个管心针孔的探针引导壳体的导管，以及用于通过相应的针尖端口向外引导一个或多个柔性护套的探针引导件，以及通过介入组织到靶组织。 主动式发射射频RF能量，其在患者体内建立RF电流。 在探针尖端处最密集的电流导致周围组织的加热以引发靶组织的消融。 本发明的一个方面包括在RF发射样式的位置处的温度感测样式，以监测被消融的组织的温度。 这允许外科医生增加关于正在进行的减轻动作的知识，以便控制施加的RF电流的强度，或者调整施加电流的时间量，或者两者。 此外还包括安装在超声波探头上的多个温度传感器，用于监测超声波探头的组织温度，同时允许超声波装置监测本发明的医疗探针装置的位置和取向。
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公开(公告)号：US5582589A
公开(公告)日：1996-12-10
申请号：US465718
申请日：1995-06-06
申请人： Stuart D. Edwards , Hugh R. Sharkey , Ingemar H. Lundquist , Ronald G. Lax , James A. Baker, Jr.
发明人： Stuart D. Edwards , Hugh R. Sharkey , Ingemar H. Lundquist , Ronald G. Lax , James A. Baker, Jr.
IPC分类号： A61B18/12 , A61B1/00 , A61B5/01 , A61B10/00 , A61B10/02 , A61B10/06 , A61B17/00 , A61B17/22 , A61B17/24 , A61B17/28 , A61B17/34 , A61B18/00 , A61B18/08 , A61B18/14 , A61B18/18 , A61B18/22 , A61B18/24 , A61B19/00 , A61F7/00 , A61K31/465 , A61M1/00 , A61M3/02 , A61M25/00 , A61M25/14 , A61N1/06 , A61N1/40 , A61N5/02 , A61N5/04 , A61N5/06 , A61B17/39
CPC分类号： A61B10/0233 , A61B10/0275 , A61B10/06 , A61B18/00 , A61B18/1477 , A61B18/1485 , A61B18/18 , A61B18/1815 , A61K31/465 , A61N1/06 , A61N1/40 , A61N1/403 , A61N5/02 , A61N5/045 , A61B1/00188 , A61B10/02 , A61B10/0241 , A61B18/14 , A61B18/1442 , A61B18/148 , A61B18/24 , A61B2017/00084 , A61B2017/00092 , A61B2017/00106 , A61B2017/00274 , A61B2017/00292 , A61B2017/003 , A61B2017/00867 , A61B2017/22072 , A61B2017/22077 , A61B2017/22082 , A61B2017/248 , A61B2017/2939 , A61B2017/3488 , A61B2018/00005 , A61B2018/00011 , A61B2018/00083 , A61B2018/00095 , A61B2018/00196 , A61B2018/0022 , A61B2018/00547 , A61B2018/00577 , A61B2018/00678 , A61B2018/00702 , A61B2018/00726 , A61B2018/00744 , A61B2018/0075 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00869 , A61B2018/00886 , A61B2018/0091 , A61B2018/00916 , A61B2018/00946 , A61B2018/00982 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/128 , A61B2018/1425 , A61B2018/2238 , A61B2090/0814 , A61B2090/3614 , A61B2090/3782 , A61B2090/3925 , A61B2217/005 , A61B2217/007 , A61M2025/0086 , A61M2025/0087 , A61M2025/0089 , A61M2025/009 , A61M2025/0096 , A61M2025/018 , A61M25/0032 , A61M25/0045 , A61M25/008 , A61M3/0279 , A61N5/04
摘要： A medical probe device of this invention comprising a catheter having a control end and a probe end. The probe end includes a stylet guide housing having at least one stylet port and stylet guide means for directing a flexible stylet outward through at least one stylet port and through intervening tissue to targeted tissues. A stylet is positioned in at least one of said stylet guide means, the stylet comprising a non-conductive sleeve having a RF electrode lumen and an optional a fluid supply lumen and a temperature sensor lumen therein. At least one portion of an opposed surface of the electrode lumen and the electrode can be spaced apart to define a liquid supply passageway for delivery of medicament liquid. The RF electrode enclosed within the non-conductive sleeve has a distal length optionally having at least one current focusing groove means thereon and a distal tip shaped to focus current crowding on its terminal end, whereby Rf current passing therefrom into surrounding tissue forms a lesion extending outward from the groove and tip. The focusing groove means can be a plurality of annular focusing grooves or a spiral focusing groove thereon.
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公开(公告)号：US5554110A
公开(公告)日：1996-09-10
申请号：US180578
申请日：1994-01-12
IPC分类号： A61B18/12 , A61B1/00 , A61B5/01 , A61B10/00 , A61B10/02 , A61B10/06 , A61B17/00 , A61B17/22 , A61B17/24 , A61B17/28 , A61B17/34 , A61B18/00 , A61B18/08 , A61B18/14 , A61B18/18 , A61B18/22 , A61B18/24 , A61B19/00 , A61F7/00 , A61K31/465 , A61M1/00 , A61M3/02 , A61M25/00 , A61M25/14 , A61N1/06 , A61N1/40 , A61N5/02 , A61N5/04 , A61N5/06 , A61B17/39
CPC分类号： A61B10/0233 , A61B10/0275 , A61B10/06 , A61B18/00 , A61B18/1477 , A61B18/1485 , A61B18/18 , A61B18/1815 , A61K31/465 , A61N1/06 , A61N1/40 , A61N1/403 , A61N5/02 , A61N5/045 , A61B1/00188 , A61B10/02 , A61B10/0241 , A61B18/14 , A61B18/1442 , A61B18/148 , A61B18/24 , A61B2017/00084 , A61B2017/00092 , A61B2017/00106 , A61B2017/00274 , A61B2017/00292 , A61B2017/003 , A61B2017/00867 , A61B2017/22072 , A61B2017/22077 , A61B2017/22082 , A61B2017/248 , A61B2017/2939 , A61B2017/3488 , A61B2018/00005 , A61B2018/00011 , A61B2018/00083 , A61B2018/00095 , A61B2018/00196 , A61B2018/0022 , A61B2018/00547 , A61B2018/00577 , A61B2018/00678 , A61B2018/00702 , A61B2018/00726 , A61B2018/00744 , A61B2018/0075 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00869 , A61B2018/00886 , A61B2018/0091 , A61B2018/00916 , A61B2018/00946 , A61B2018/00982 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/128 , A61B2018/1425 , A61B2018/2238 , A61B2090/0814 , A61B2090/3614 , A61B2090/3782 , A61B2090/3925 , A61B2217/005 , A61B2217/007 , A61M2025/0086 , A61M2025/0087 , A61M2025/0089 , A61M2025/009 , A61M2025/0096 , A61M2025/018 , A61M25/0032 , A61M25/0045 , A61M25/008 , A61M3/0279 , A61N5/04
摘要： A medical probe device including a catheter having a stylet guide housing with one or more stylet ports in a side wall thereof and a for directing a flexible stylet outward through the stylet port and through intervening tissue at a preselected, adjustable angle to a target tissue. The total catheter assembly includes a stylet guide lumen communicating with the stylet port and a stylet positioned in said stylet guide lumen for longitudinal movement from the port through intervening tissue to a target tissue. The stylet can be an electrical conductor enclosed within a non-conductive layer, the electrical conductor being a radio frequency electrode. During the ablation operation, the tissue immediately adjacent the stylet can become desiccated, thereby necessitating an increase of current flow and a loss of ablation efficiency. A forward and reverse movement of the non-conductive sleeve on the stylet during an operation frees the stylet from sticking tissue and creates a space around the electrode to allow the tissue to rehydrate.
摘要翻译： 一种医疗探针装置，其包括导管，该导管具有在其侧壁中具有一个或多个管心针端口的探针引导壳体，以及用于将柔性探针向外引导通过探针端口，并通过介入组织以与靶组织预选的可调节角度。 总导管组件包括与通管孔端口连通的探针引导腔和位于所述探针引导腔中的探针，用于从端口到介入组织到目标组织的纵向移动。 探针可以是封装在非导电层内的电导体，电导体是射频电极。 在消融操作期间，紧邻探针针的组织可能变干，从而需要电流增加和消融效率的降低。 在操作期间非导电套管在探针上的向前和反向运动使探针从粘附组织释放，并在电极周围产生空间以允许组织再水合。
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公开(公告)号：US5542915A
公开(公告)日：1996-08-06
申请号：US180511
申请日：1994-01-12
IPC分类号： A61B10/00 , A61B10/02 , A61B10/06 , A61B17/00 , A61B17/22 , A61B17/24 , A61B17/28 , A61B17/34 , A61B18/00 , A61B18/08 , A61B18/14 , A61B18/18 , A61B18/22 , A61B18/24 , A61B19/00 , A61F7/00 , A61M1/00 , A61M3/02 , A61M25/00 , A61N1/06 , A61N1/40 , A61N5/02 , A61N5/04 , A61B17/39
CPC分类号： A61B10/0233 , A61B10/0275 , A61B10/06 , A61B18/00 , A61B18/1477 , A61B18/1482 , A61B18/1485 , A61B18/18 , A61B18/1815 , A61B18/24 , A61N1/06 , A61N1/40 , A61N1/403 , A61N5/02 , A61N5/045 , A61B10/0241 , A61B18/082 , A61B18/1206 , A61B18/14 , A61B18/1402 , A61B18/1442 , A61B18/148 , A61B2017/00084 , A61B2017/00092 , A61B2017/00101 , A61B2017/00106 , A61B2017/00123 , A61B2017/00181 , A61B2017/00194 , A61B2017/00274 , A61B2017/00292 , A61B2017/003 , A61B2017/00867 , A61B2017/22038 , A61B2017/22072 , A61B2017/22077 , A61B2017/22082 , A61B2017/248 , A61B2017/2939 , A61B2017/3488 , A61B2018/00005 , A61B2018/00011 , A61B2018/00041 , A61B2018/00083 , A61B2018/00095 , A61B2018/00101 , A61B2018/00196 , A61B2018/0022 , A61B2018/00547 , A61B2018/00577 , A61B2018/00678 , A61B2018/00702 , A61B2018/00726 , A61B2018/00744 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00886 , A61B2018/0091 , A61B2018/00916 , A61B2018/00946 , A61B2018/0097 , A61B2018/00982 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/128 , A61B2018/1425 , A61B2018/1861 , A61B2018/2238 , A61B2090/0814 , A61B2090/3614 , A61B2090/378 , A61B2090/3782 , A61B2090/3786 , A61B2090/3925 , A61B2217/005 , A61B2217/007 , A61F2007/0054 , A61M2025/0086 , A61M2025/0087 , A61M2025/0089 , A61M2025/0096 , A61M2025/018 , A61M25/0068 , A61M3/0279 , A61N5/04
摘要： A medical probe apparatus comprising a catheter having a stylet guide housing with one or more stylet ports therein and stylet guides for directing one or more flexible stylets outward through respective stylet ports and through intervening tissue to target tissue. The active stylets emit radio frequency RF energy which establishes an RF current in the patient. The current, being densest at the stylet tips, causes heating of the surrounding tissue to initiate ablation of the target tissue. One aspect of the invention includes temperature sensing stylets at the location of the RF emitting stylets to monitor the temperature of the tissue being ablated. This allows the surgeon to have increased knowledge about the abating action under way in order to control the intensity of the applied RF current, or to adjust the amount of time the current is applied, or both. Further included herein is a plurality of temperature sensors mounted on an ultrasound probe to be used to monitor tissue temperature at the ultrasound probe while allowing the ultrasound device to monitor the position and orientation of the medical probe apparatus of the present invention.
摘要翻译： 一种医疗探针装置，包括具有其中具有一个或多个管心针孔的探针引导壳体的导管，以及用于通过相应的针尖端口向外引导一个或多个柔性护套的探针引导件，以及通过介入组织到靶组织。 主动式发射射频RF能量，其在患者体内建立RF电流。 在探针尖端处最密集的电流导致周围组织的加热以引发靶组织的消融。 本发明的一个方面包括在RF发射样式的位置处的温度感测样式，以监测被消融的组织的温度。 这允许外科医生增加关于正在进行的减轻动作的知识，以便控制施加的RF电流的强度，或者调整施加电流的时间量，或者两者。 此外还包括安装在超声波探头上的多个温度传感器，用于监测超声波探头的组织温度，同时允许超声波装置监测本发明的医疗探针装置的位置和取向。
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5.发明授权
公开(公告)号：US5762626A
公开(公告)日：1998-06-09
申请号：US701887
申请日：1996-08-23
申请人： Ingemar H. Lundquist , Stuart D. Edwards , Hugh R. Sharkey , Ronald G. Lax , James A. Baker, Jr. , Phillip R. Sommer
发明人： Ingemar H. Lundquist , Stuart D. Edwards , Hugh R. Sharkey , Ronald G. Lax , James A. Baker, Jr. , Phillip R. Sommer
IPC分类号： A61N5/02 , A61B10/00 , A61B10/02 , A61B10/06 , A61B17/00 , A61B17/22 , A61B17/24 , A61B17/28 , A61B17/34 , A61B18/00 , A61B18/08 , A61B18/14 , A61B18/18 , A61B18/22 , A61B18/24 , A61B19/00 , A61F7/00 , A61M20060101 , A61M1/00 , A61M3/02 , A61M25/00 , A61M25/01 , A61N1/06 , A61N1/40 , A61N5/04 , A61B17/39
CPC分类号： A61B18/00 , A61B10/0233 , A61B10/0275 , A61B10/06 , A61B18/1477 , A61B18/1482 , A61B18/1485 , A61B18/18 , A61B18/1815 , A61M25/0136 , A61N1/06 , A61N1/40 , A61N1/403 , A61N5/02 , A61N5/045 , A61B10/02 , A61B10/0241 , A61B18/14 , A61B18/1442 , A61B18/148 , A61B18/24 , A61B2017/00084 , A61B2017/00092 , A61B2017/00101 , A61B2017/00106 , A61B2017/00274 , A61B2017/00292 , A61B2017/003 , A61B2017/00867 , A61B2017/22072 , A61B2017/22077 , A61B2017/22082 , A61B2017/248 , A61B2017/2939 , A61B2017/3488 , A61B2018/00005 , A61B2018/00011 , A61B2018/00041 , A61B2018/00083 , A61B2018/00095 , A61B2018/00196 , A61B2018/0022 , A61B2018/00547 , A61B2018/00577 , A61B2018/00678 , A61B2018/00702 , A61B2018/00726 , A61B2018/00744 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00886 , A61B2018/0091 , A61B2018/00916 , A61B2018/00946 , A61B2018/00982 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/128 , A61B2018/1425 , A61B2018/1861 , A61B2018/2238 , A61B2090/0814 , A61B2090/3614 , A61B2090/3782 , A61B2090/3925 , A61B2217/005 , A61F2007/0054 , A61M2025/0089 , A61M2025/0091 , A61M2025/0096 , A61M2025/018 , A61M3/0279 , A61N5/04
摘要： A transurethral needle ablation device for the treatment of the prostate of a human male using radio frequency energy wall comprising a sheath having a lumen extending therethrough. A guide tube assembly is slidably mounted in the lumen in the sheath and having a lumen extending therethrough. A needle electrode is slidably mounted in the lumen in the guide tube assembly. An insulating sheath is disposed about the needle electrode so that the distal extremity of the needle electrode is exposed. A handle adapted to be gripped by the human hand is mounted on the proximal extremity of the sheath. Levers are carried by the handle for causing bending of the distal extremity of the guide tube assembly at an angle with respect to its longitudinal axis whereby the lumen in the guide tube assembly can be directed so that it faces the urethral wall. A control is carried by the handle and coupled to the needle electrode and the insulating sleeve for advancing and retracting the needle electrode with respect to the guide tube assembly whereby when the sheath is positioned in the urethra with its distal extremity in the vicinity of the prostate, the needle electrode can be advanced through the urethral wall and into the tissue of the prostate to permit the application of radio frequency energy to the tissue of the prostate surrounding the needle electrode to form a lesion in the prostate.
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公开(公告)号：US5591125A
公开(公告)日：1997-01-07
申请号：US470621
申请日：1995-06-06
申请人： Stuart D. Edwards , Hugh R. Sharkey , Ingemar H. Lundquist , Ronald G. Lax , James A. Baker, Jr.
发明人： Stuart D. Edwards , Hugh R. Sharkey , Ingemar H. Lundquist , Ronald G. Lax , James A. Baker, Jr.
IPC分类号： A61B18/12 , A61B1/00 , A61B5/01 , A61B10/00 , A61B10/02 , A61B10/06 , A61B17/00 , A61B17/22 , A61B17/24 , A61B17/28 , A61B17/34 , A61B18/00 , A61B18/08 , A61B18/14 , A61B18/18 , A61B18/22 , A61B18/24 , A61B19/00 , A61F7/00 , A61K31/465 , A61M1/00 , A61M3/02 , A61M25/00 , A61M25/14 , A61N1/06 , A61N1/40 , A61N5/02 , A61N5/04 , A61N5/06 , A61B17/39
CPC分类号： A61B10/0233 , A61B10/0275 , A61B10/06 , A61B18/00 , A61B18/1477 , A61B18/1485 , A61B18/18 , A61B18/1815 , A61K31/465 , A61N1/06 , A61N1/40 , A61N1/403 , A61N5/02 , A61N5/045 , A61B1/00188 , A61B10/02 , A61B10/0241 , A61B18/14 , A61B18/1442 , A61B18/148 , A61B18/24 , A61B2017/00084 , A61B2017/00092 , A61B2017/00106 , A61B2017/00274 , A61B2017/00292 , A61B2017/003 , A61B2017/00867 , A61B2017/22072 , A61B2017/22077 , A61B2017/22082 , A61B2017/248 , A61B2017/2939 , A61B2017/3488 , A61B2018/00005 , A61B2018/00011 , A61B2018/00083 , A61B2018/00095 , A61B2018/00196 , A61B2018/0022 , A61B2018/00547 , A61B2018/00577 , A61B2018/00678 , A61B2018/00702 , A61B2018/00726 , A61B2018/00744 , A61B2018/0075 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00869 , A61B2018/00886 , A61B2018/0091 , A61B2018/00916 , A61B2018/00946 , A61B2018/00982 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/128 , A61B2018/1425 , A61B2018/2238 , A61B2090/0814 , A61B2090/3614 , A61B2090/3782 , A61B2090/3925 , A61B2217/005 , A61B2217/007 , A61M2025/0086 , A61M2025/0087 , A61M2025/0089 , A61M2025/009 , A61M2025/0096 , A61M2025/018 , A61M25/0032 , A61M25/0045 , A61M25/008 , A61M3/0279 , A61N5/04
摘要： A medical probe device of this invention comprising a catheter having a control end and a probe end. The probe end includes a stylet guide housing having at least one stylet port and stylet guide means for directing a flexible stylet outward through at least one stylet port and through intervening tissue to targeted tissues. A stylet is positioned in at least one of said stylet guide means, the stylet comprising a non-conductive sleeve having a RF electrode lumen and an optional a fluid supply lumen and a temperature sensor lumen therein. At least one portion of an opposed surface of the electrode lumen and the electrode can be spaced apart to define a liquid supply passageway for delivery of medicament liquid. The RF electrode enclosed within the non-conductive sleeve has a distal length optionally having at least one current focusing groove means thereon and a distal tip shaped to focus current crowding on its terminal end, whereby Rf current passing therefrom into surrounding tissue forms a lesion extending outward from the groove and tip. The focusing groove means can be a plurality of annular focusing grooves or a spiral focusing groove thereon.
摘要翻译： 本发明的医疗探针装置包括具有控制端和探针端的导管。 探针端部包括具有至少一个探针端口和探针引导装置的探针引导壳体，用于将柔性探针向外引导通过至少一个通管孔，并通过介入组织引导到靶组织。 探针定位在所述探针引导装置中的至少一个上，所述探针包括具有RF电极腔和可选的流体供应管腔和其中的温度传感器腔的非导电套管。 电极腔和电极的相对表面的至少一部分可以间隔开以限定用于输送药液的液体供应通道。 封闭在非导电套筒内的RF电极具有任选地在其上具有至少一个电流聚焦槽装置的远端长度，以及形成为将电流拥挤聚焦在其末端上的远端，其中从其进入周围组织的Rf电流形成延伸的病变 从凹槽和尖端向外。 聚焦槽装置可以是多个环形聚焦槽或其上的螺旋形聚焦槽。
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公开(公告)号：US06241702B1
公开(公告)日：2001-06-05
申请号：US09094255
申请日：1998-06-09
申请人： Ingemar H. Lundquist , Stuart D. Edwards , Hugh R. Sharkey , Ronald G. Lax , James A. Baker, Jr. , Phillip R. Sommer
发明人： Ingemar H. Lundquist , Stuart D. Edwards , Hugh R. Sharkey , Ronald G. Lax , James A. Baker, Jr. , Phillip R. Sommer
IPC分类号： A61B1720
CPC分类号： A61B18/00 , A61B10/02 , A61B10/0233 , A61B10/0241 , A61B10/0275 , A61B10/06 , A61B18/14 , A61B18/1477 , A61B18/148 , A61B18/1482 , A61B18/1485 , A61B18/18 , A61B18/1815 , A61B18/24 , A61B2017/00084 , A61B2017/00092 , A61B2017/00101 , A61B2017/00106 , A61B2017/00274 , A61B2017/00292 , A61B2017/003 , A61B2017/00867 , A61B2017/22072 , A61B2017/22077 , A61B2017/22082 , A61B2017/248 , A61B2017/2939 , A61B2017/3488 , A61B2018/00005 , A61B2018/00011 , A61B2018/00041 , A61B2018/00083 , A61B2018/00095 , A61B2018/00196 , A61B2018/0022 , A61B2018/00547 , A61B2018/00577 , A61B2018/00678 , A61B2018/00702 , A61B2018/00726 , A61B2018/00744 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00886 , A61B2018/0091 , A61B2018/00916 , A61B2018/00946 , A61B2018/00982 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/128 , A61B2018/1425 , A61B2018/1861 , A61B2018/2238 , A61B2090/0814 , A61B2090/3614 , A61B2090/3782 , A61B2090/3925 , A61B2217/005 , A61F2007/0054 , A61M3/0279 , A61M25/0136 , A61M2025/0089 , A61M2025/0091 , A61M2025/0096 , A61M2025/018 , A61N1/06 , A61N1/40 , A61N1/403 , A61N5/02 , A61N5/04 , A61N5/045
摘要： A medical device for the treatment by radio frequency ablation of a target volume in tissue of a prostate comprising an elongate probe member having proximal and distal extremities and having a passage therein extending from the proximal extremity to the distal extremity. The elongate probe member is sized so that it can be introduced into the urethra. At least one guide tube having proximal and distal extremities is mounted in the passage of the elongate probe member for nonlongitudinal movement therein. The at least one guide tube has a lumen extending therethrough from the proximal extremity to the distal extremity. A radio frequency conductive electrode is disposed in the lumen. A handle is coupled to the proximal extremity of the elongate probe member and includes a finger actuatable mechanism secured to the radio frequency electrode for advancing and retracting the radio frequency electrode with respect to the at least one guide tube. The distal extremity of the at least one guide tube has a curved surface for directing the radio frequency electrode sidewise of the longitudinal axis into the tissue of the prostate.
摘要翻译： 一种医疗装置，用于通过射线消融前列腺组织中的目标体积进行治疗，其包括具有近端和远端的细长探针部件，并且具有从近端至远端延伸的通道。 细长的探针构件的尺寸使得其可以被引入到尿道中。 具有近端和远端的至少一个导管安装在细长探针构件的通道中，用于在其中非纵向移动。 所述至少一个引导管具有从近端至远端延伸通过的内腔。 射频导电电极设置在内腔中。 手柄耦合到细长探针构件的近端，并且包括固定到射频电极的手指可致动机构，用于相对于至少一个导管推进和缩回射频电极。 所述至少一个引导管的远端具有弯曲表面，用于将射频电极侧向纵向轴线引导到前列腺的组织中。
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公开(公告)号：US5421819A
公开(公告)日：1995-06-06
申请号：US61647
申请日：1993-05-13
申请人： Stuart D. Edwards , Hugh R. Sharkey , Ingemar H. Lundquist , Ronald G. Lax , James A. Baker, Jr.
发明人： Stuart D. Edwards , Hugh R. Sharkey , Ingemar H. Lundquist , Ronald G. Lax , James A. Baker, Jr.
IPC分类号： A61B18/12 , A61B1/00 , A61B5/01 , A61B10/00 , A61B10/02 , A61B10/06 , A61B17/00 , A61B17/22 , A61B17/24 , A61B17/28 , A61B17/34 , A61B18/00 , A61B18/08 , A61B18/14 , A61B18/18 , A61B18/22 , A61B18/24 , A61B19/00 , A61F7/00 , A61K31/465 , A61M1/00 , A61M3/02 , A61M25/00 , A61M25/14 , A61N1/06 , A61N1/40 , A61N5/02 , A61N5/04 , A61N5/06 , A61B17/39
CPC分类号： A61B10/0233 , A61B10/0275 , A61B10/06 , A61B18/00 , A61B18/1477 , A61B18/1485 , A61B18/18 , A61B18/1815 , A61K31/465 , A61N1/06 , A61N1/40 , A61N1/403 , A61N5/02 , A61N5/045 , A61B1/00188 , A61B10/02 , A61B10/0241 , A61B18/14 , A61B18/1442 , A61B18/148 , A61B18/24 , A61B2017/00084 , A61B2017/00092 , A61B2017/00106 , A61B2017/00274 , A61B2017/00292 , A61B2017/003 , A61B2017/00867 , A61B2017/22072 , A61B2017/22077 , A61B2017/22082 , A61B2017/248 , A61B2017/2939 , A61B2017/3488 , A61B2018/00005 , A61B2018/00011 , A61B2018/00083 , A61B2018/00095 , A61B2018/00196 , A61B2018/0022 , A61B2018/00547 , A61B2018/00577 , A61B2018/00678 , A61B2018/00702 , A61B2018/00726 , A61B2018/00744 , A61B2018/0075 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00869 , A61B2018/00886 , A61B2018/0091 , A61B2018/00916 , A61B2018/00946 , A61B2018/00982 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/128 , A61B2018/1425 , A61B2018/2238 , A61B2090/0814 , A61B2090/3614 , A61B2090/3782 , A61B2090/3925 , A61B2217/005 , A61B2217/007 , A61M2025/0086 , A61M2025/0087 , A61M2025/0089 , A61M2025/009 , A61M2025/0096 , A61M2025/018 , A61M25/0032 , A61M25/0045 , A61M25/008 , A61M3/0279 , A61N5/04
摘要： A medical probe device of this invention comprising a catheter having a control end and a probe end. The probe end includes a stylet guide housing having at least one stylet port and stylet guide means for directing a flexible stylet outward through at least one stylet port and through intervening tissue to targeted tissues. A stylet is positioned in at least one of said stylet guide means, the stylet comprising a non-conductive sleeve having a RF electrode lumen and an optional a fluid supply lumen and a temperature sensor lumen therein. At least one portion of an opposed surface of the electrode lumen and the electrode can be spaced apart to define a liquid supply passageway for delivery of medicament liquid. The RF electrode enclosed within the non-conductive sleeve has a distal length optionally having at least one current focusing groove means thereon and a distal tip shaped to focus current crowding on its terminal end, whereby Rf current passing therefrom into surrounding tissue forms a lesion extending outward from the groove and tip. The focusing groove means can be a plurality of annular focusing grooves or a spiral focusing groove thereon.
摘要翻译： 本发明的医疗探针装置包括具有控制端和探针端的导管。 探针端部包括具有至少一个探针端口和探针引导装置的探针引导壳体，用于通过至少一个管心针孔将柔性探针向外引导并通过介入组织引导到靶组织。 探针定位在所述探针引导装置中的至少一个上，所述探针包括具有RF电极腔和可选的流体供应管腔和其中的温度传感器腔的非导电套管。 电极腔和电极的相对表面的至少一部分可以间隔开以限定用于输送药液的液体供应通道。 封闭在非导电套筒内的RF电极具有任选地在其上具有至少一个电流聚焦槽装置的远端长度，以及形成为将电流拥挤聚焦在其末端上的远端，其中从其进入周围组织的Rf电流形成延伸的病变 从凹槽和尖端向外。 聚焦槽装置可以是多个环形聚焦槽或其上的螺旋形聚焦槽。
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9.发明授权Transurethral needle ablation device with cystoscope and method for treatment of the prostate 失效具有膀胱镜的经尿道针消融装置及前列腺治疗方法
公开(公告)号：US5549644A
公开(公告)日：1996-08-27
申请号：US191258
申请日：1994-02-02
申请人： Ingemar H. Lundquist , Stuart D. Edwards , Hugh R. Sharkey , Ronald G. Lax , James A. Baker, Jr. , Phillip R. Sommer
发明人： Ingemar H. Lundquist , Stuart D. Edwards , Hugh R. Sharkey , Ronald G. Lax , James A. Baker, Jr. , Phillip R. Sommer
IPC分类号： A61N5/02 , A61B10/00 , A61B10/02 , A61B10/06 , A61B17/00 , A61B17/22 , A61B17/24 , A61B17/28 , A61B17/34 , A61B18/00 , A61B18/08 , A61B18/14 , A61B18/18 , A61B18/22 , A61B18/24 , A61B19/00 , A61F7/00 , A61M20060101 , A61M1/00 , A61M3/02 , A61M25/00 , A61M25/01 , A61N1/06 , A61N1/40 , A61N5/04 , A61B17/39
CPC分类号： A61B18/00 , A61B10/0233 , A61B10/0275 , A61B10/06 , A61B18/1477 , A61B18/1482 , A61B18/1485 , A61B18/18 , A61B18/1815 , A61M25/0136 , A61N1/06 , A61N1/40 , A61N1/403 , A61N5/02 , A61N5/045 , A61B10/02 , A61B10/0241 , A61B18/14 , A61B18/1442 , A61B18/148 , A61B18/24 , A61B2017/00084 , A61B2017/00092 , A61B2017/00101 , A61B2017/00106 , A61B2017/00274 , A61B2017/00292 , A61B2017/003 , A61B2017/00867 , A61B2017/22072 , A61B2017/22077 , A61B2017/22082 , A61B2017/248 , A61B2017/2939 , A61B2017/3488 , A61B2018/00005 , A61B2018/00011 , A61B2018/00041 , A61B2018/00083 , A61B2018/00095 , A61B2018/00196 , A61B2018/0022 , A61B2018/00547 , A61B2018/00577 , A61B2018/00678 , A61B2018/00702 , A61B2018/00726 , A61B2018/00744 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00886 , A61B2018/0091 , A61B2018/00916 , A61B2018/00946 , A61B2018/00982 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/128 , A61B2018/1425 , A61B2018/1861 , A61B2018/2238 , A61B2090/0814 , A61B2090/3614 , A61B2090/3782 , A61B2090/3925 , A61B2217/005 , A61F2007/0054 , A61M2025/0089 , A61M2025/0091 , A61M2025/0096 , A61M2025/018 , A61M3/0279 , A61N5/04
摘要： A transurethral needle ablation device for the treatment of the prostate of a human male using radio frequency energy wall comprising a sheath having a lumen extending therethrough. A guide tube assembly is slidably mounted in the lumen in the sheath and having a lumen extending therethrough. A needle electrode is slidably mounted in the lumen in the guide tube assembly. An insulating sheath is disposed about the needle electrode so that the distal extremity of the needle electrode is exposed. A handle adapted to be gripped by the human hand is mounted on the proximal extremity of the sheath. Levers are carried by the handle for causing bending of the distal extremity of the guide tube assembly at an angle with respect to its longitudinal axis whereby the lumen in the guide tube assembly can be directed so that it faces the urethral wall. A control is carried by the handle and coupled to the needle electrode and the insulating sleeve for advancing and retracting the needle electrode with respect to the guide tube assembly whereby when the sheath is positioned in the urethra with its distal extremity in the vicinity of the prostate, the needle electrode can be advanced through the urethral wall and into the tissue of the prostate to permit the application of radio frequency energy to the tissue of the prostate surrounding the needle electrode to form a lesion in the prostate.
摘要翻译： 一种用于治疗男性前列腺的经尿道针消融装置，其使用射频能量壁，其包括具有延伸穿过其中的内腔的护套。 引导管组件可滑动地安装在护套中的内腔中并且具有延伸穿过其中的内腔。 针电极可滑动地安装在导管组件的内腔中。 绝缘护套设置在针电极周围，使得针电极的远端露出。 适于被人的手抓住的手柄安装在护套的近端上。 杠杆由手柄承载，以引导导管组件的远端末端相对于其纵向轴线成一定角度，由此引导管组件中的内腔可被定向以使其面向尿道壁。 控制手柄由手柄承载并且联接到针电极和绝缘套筒上，用于相对于导管组件推进和缩回针电极，由此当护套定位在尿道中时，其远端在前列腺附近 针状电极可以通过尿道壁前进并进入前列腺的组织，以允许将射频能量施加到针电极周围的前列腺组织，以在前列腺中形成病变。
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公开(公告)号：US5435805A
公开(公告)日：1995-07-25
申请号：US62364
申请日：1993-05-13
申请人： Stuart D. Edwards , Hugh R. Sharkey , Ingemar H. Lundquist , Ronald G. Lax , James A. Baker, Jr.
发明人： Stuart D. Edwards , Hugh R. Sharkey , Ingemar H. Lundquist , Ronald G. Lax , James A. Baker, Jr.
IPC分类号： A61B1/018 , A61B5/01 , A61B10/00 , A61B10/02 , A61B10/06 , A61B17/00 , A61B17/22 , A61B17/24 , A61B17/28 , A61B17/34 , A61B18/00 , A61B18/08 , A61B18/12 , A61B18/14 , A61B18/18 , A61B18/22 , A61B18/24 , A61B19/00 , A61F7/00 , A61M1/00 , A61M3/02 , A61M25/00 , A61N1/06 , A61N1/40 , A61N5/04 , A61B17/39
CPC分类号： A61B10/0233 , A61B10/0275 , A61B10/06 , A61B18/00 , A61B18/1442 , A61B18/1477 , A61B18/1485 , A61B18/18 , A61B18/1815 , A61N1/06 , A61N1/40 , A61N1/403 , A61N5/045 , A61B10/02 , A61B10/0241 , A61B18/14 , A61B18/148 , A61B18/24 , A61B2017/00084 , A61B2017/00092 , A61B2017/00101 , A61B2017/00106 , A61B2017/00123 , A61B2017/00181 , A61B2017/00194 , A61B2017/00274 , A61B2017/00292 , A61B2017/00296 , A61B2017/003 , A61B2017/00867 , A61B2017/22072 , A61B2017/22077 , A61B2017/22082 , A61B2017/248 , A61B2017/2939 , A61B2017/3488 , A61B2018/00005 , A61B2018/00011 , A61B2018/00023 , A61B2018/00083 , A61B2018/00095 , A61B2018/00101 , A61B2018/00196 , A61B2018/0022 , A61B2018/00291 , A61B2018/00327 , A61B2018/00547 , A61B2018/00577 , A61B2018/00678 , A61B2018/00702 , A61B2018/00726 , A61B2018/00744 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00875 , A61B2018/00886 , A61B2018/0091 , A61B2018/00916 , A61B2018/00946 , A61B2018/00982 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/128 , A61B2018/1412 , A61B2018/1425 , A61B2018/2238 , A61B2090/0814 , A61B2090/3614 , A61B2090/378 , A61B2090/3782 , A61B2090/3786 , A61B2090/3925 , A61B2217/005 , A61B2217/007 , A61B2218/003 , A61F2007/0054 , A61M2025/0086 , A61M2025/0087 , A61M2025/0089 , A61M2025/009 , A61M2025/0096 , A61M2025/018 , A61M25/0068 , A61M25/0069 , A61M25/0082 , A61M3/0279 , A61N5/04
摘要： A medical probe device comprising a catheter having a stylet guide housing with at least one stylet port in a side thereof and stylet guide means for directing a flexible stylet outward through at least one stylet port and through intervening tissue to targeted tissues. The stylet guide housing has an optical viewing means positioned for viewing the stylet and adjacent structure which includes a fiber optic channel means for receiving a fiber optic viewing device. The fiber optic channel means can include a guide port means for directing longitudinal movement of a fiber optic device with respect to the stylet guide means in a viewing zone and a flushing liquid channel in the stylet guide housing having an exit port positioned to direct flushing liquid issuing therefrom across the end of a fiber optic device when positioned in the viewing zone. The optical viewing means can comprise a viewing window positioned in the stylet guide housing for viewing the stylet when it is directed outward from its respective stylet port. The optical viewing means can include a fiber optic channel in the stylet guide housing for receiving the a fiber optic viewing device and aligning the viewing end thereof with the viewing window. Windowed devices can include a flushing liquid channel in the stylet guide housing having an exit port positioned to direct flushing liquid issuing therefrom across a surface of the viewing window.
摘要翻译： 一种医疗探针装置，其包括导管，该导管具有在其侧面具有至少一个管心针端口的探针引导壳体和用于通过至少一个通管孔向外引导柔性探针管的探针引导装置，并通过介入组织向目标组织引导。 探针引导壳体具有光学观察装置，用于观察探针和相邻结构，其包括用于接收光纤观察装置的光纤通道装置。 光纤通道装置可以包括引导端口装置，用于在观察区域引导光纤装置相对于探针引导装置的纵向移动，并且在通道引导壳体中的冲洗液体通道具有出口端口，定位成引导冲洗液体 当定位在观察区域时，从光纤设备的端部发出。 光学观察装置可以包括定位在探针引导壳体中的观察窗，用于当其从其各自的管心针端口向外指示时，用于观察探针。 光学观察装置可以包括在探针引导壳体中的光纤通道，用于接收光纤观察装置并将其观察端与观察窗对准。 开窗装置可以包括探针引导壳体中的冲洗液体通道，其具有出口端口，该出口端口定位成直接从其观察窗口的表面引导从其中排出的冲洗液体。
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