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公开(公告)号：US08994940B2
公开(公告)日：2015-03-31
申请号：US13204206
申请日：2011-08-05
CPC分类号： G01N21/4785 , G01N21/53 , G01N2021/4707
摘要： Disclosed is a fine particle measurement apparatus including a light condensing unit that condenses irradiated light irradiated to a sample flow where fine particles pass through and directly propagates the light without scattering, and scattered light scattered by the fine particles to an optical receiver divided into a plurality of regions; a position controller that controls the relative positions of members of an optical path; and a control unit that detects positions of condensing spots of the irradiated light and the scattered light based on signal intensities of each region of the optical receiver, and controls the position controller such that the positions of the condensing spots of the irradiated light and the scattered light match with each other.
摘要翻译： 公开了一种微粒测量装置，其包括聚光单元，该聚光单元将照射到微粒通过的样品流的照射光与不散射直接传播的光以及由微粒散射的散射光聚光到被分成多个的光接收体 的地区; 位置控制器，其控制光路的构件的相对位置; 以及控制单元，其基于所述光接收器的各区域的信号强度来检测所述照射光和所述散射光的聚光点的位置，并且控制所述位置控制器，使得所述照射光的聚光点和所述散射光的位置 光线相互匹配。
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公开(公告)号：US20120050737A1
公开(公告)日：2012-03-01
申请号：US13204206
申请日：2011-08-05
IPC分类号： G01N21/47
CPC分类号： G01N21/4785 , G01N21/53 , G01N2021/4707
摘要： Disclosed is a fine particle measurement apparatus including a light condensing unit that condenses irradiated light irradiated to a sample flow where fine particles pass through and directly propagates the light without scattering, and scattered light scattered by the fine particles to an optical receiver divided into a plurality of regions; a position controller that controls the relative positions of members of an optical path; and a control unit that detects positions of condensing spots of the irradiated light and the scattered light based on signal intensities of each region of the optical receiver, and controls the position controller such that the positions of the condensing spots of the irradiated light and the scattered light match with each other.
摘要翻译： 公开了一种微粒测量装置，其包括聚光单元，该聚光单元将照射到微粒通过的样品流的照射光与不散射直接传播的光以及由微粒散射的散射光聚光到被分成多个的光接收体 的地区; 位置控制器，其控制光路的构件的相对位置; 以及控制单元，其基于所述光接收器的各区域的信号强度来检测所述照射光和所述散射光的聚光点的位置，并且控制所述位置控制器，使得所述照射光的聚光点和所述散射光的位置 光线相互匹配。
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公开(公告)号：US20110222050A1
公开(公告)日：2011-09-15
申请号：US13042930
申请日：2011-03-08
CPC分类号： G01N15/1434 , G01N15/1459 , G01N21/64 , G01N21/645 , G01N2015/1493 , G01N2021/4716
摘要： Disclosed herein is an optical measuring device including: a light applying section configured to apply exciting light to a sample flowing in a channel; and a scattered light detecting section configured to detect scattered light generated from the sample irradiated with the exciting light on the downstream side of the sample in the traveling direction of the exciting light; the scattered light detecting section including a scattered light separating mask for separating the scattered light into a low numerical aperture component having a numerical aperture not greater than a specific value and a high numerical aperture component having a numerical aperture greater than the specific value; a first detector for detecting the low numerical aperture component; and a second detector for detecting the high numerical aperture component.
摘要翻译： 本发明公开了一种光学测量装置，包括：光施加部，被配置为向在通道中流动的样品施加激发光; 以及散射光检测部，被配置为检测在激发光的行进方向上在样品的下游侧照射的激光的样品产生的散射光; 散射光检测部分包括用于将散射光分离成具有不大于特定值的数值孔径的低数值孔径分量的散射光分离掩模和具有大于该特定值的数值孔径的高数值孔径分量; 用于检测低数值孔径分量的第一检测器; 以及用于检测高数值孔径分量的第二检测器。
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公开(公告)号：US08780338B2
公开(公告)日：2014-07-15
申请号：US13042930
申请日：2011-03-08
IPC分类号： G01N21/00
CPC分类号： G01N15/1434 , G01N15/1459 , G01N21/64 , G01N21/645 , G01N2015/1493 , G01N2021/4716
摘要： Disclosed herein is an optical measuring device including: a light applying section configured to apply exciting light to a sample flowing in a channel; and a scattered light detecting section configured to detect scattered light generated from the sample irradiated with the exciting light on the downstream side of the sample in the traveling direction of the exciting light; the scattered light detecting section including a scattered light separating mask for separating the scattered light into a low numerical aperture component having a numerical aperture not greater than a specific value and a high numerical aperture component having a numerical aperture greater than the specific value; a first detector for detecting the low numerical aperture component; and a second detector for detecting the high numerical aperture component.
摘要翻译： 本发明公开了一种光学测量装置，包括：光施加部，被配置为向在通道中流动的样品施加激发光; 以及散射光检测部，被配置为检测在激发光的行进方向上在样品的下游侧照射的激光的样品产生的散射光; 散射光检测部分包括用于将散射光分离成具有不大于特定值的数值孔径的低数值孔径分量的散射光分离掩模和具有大于该特定值的数值孔径的高数值孔径分量; 用于检测低数值孔径分量的第一检测器; 以及用于检测高数值孔径分量的第二检测器。
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公开(公告)号：US08736824B2
公开(公告)日：2014-05-27
申请号：US13561820
申请日：2012-07-30
申请人： Eriko Matsui , Suguru Dowaki , Hirokazu Tatsuta , Takeshi Kunihiro , Akira Niwa , Megumu Saito , Tatsutoshi Nakahata
发明人： Eriko Matsui , Suguru Dowaki , Hirokazu Tatsuta , Takeshi Kunihiro , Akira Niwa , Megumu Saito , Tatsutoshi Nakahata
CPC分类号： G01N15/05 , G01N21/31 , G01N21/33 , G01N33/49 , G01N2021/3144 , G01N2021/3155
摘要： A blood analysis apparatus includes an analysis section. The analysis section is configured to compare a measurement spectrum obtained regarding red blood cells with a standard spectrum of heme, biliverdin, and bilirubin, and cause the measurement spectrum to belong to any one of the standard spectra.
摘要翻译： 血液分析装置包括分析部。 分析部将比较红细胞的测定光谱与血红素，胆红素，胆红素的标准光谱进行比较，使测定光谱属于任一标准光谱。
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公开(公告)号：US08687190B2
公开(公告)日：2014-04-01
申请号：US13180736
申请日：2011-07-12
申请人： Suguru Dowaki
发明人： Suguru Dowaki
IPC分类号： G01N21/00
CPC分类号： G01N15/1459 , G01N15/1434
摘要： A fine particle detector includes a light emitting system letting light from a light source pass through a phase difference element and focusing the light on a sample flow through which fine particles flow. When the direction of the sample flow is an X-axis direction, the light is emitted to the sample flow in a Z-direction, and a ZX-plane is orthogonal to a Y-direction, then the phase difference element has a plurality of regions divided in the Y-axis direction and causes a phase difference between wavefronts of the light passing through the plurality of regions.
摘要翻译： 细粒子检测器包括使来自光源的光通过相位差元件的发光系统，并将光聚焦在微粒流过的样品流中。 当样品流动的方向为X轴方向时，光沿Z方向发射到样品流，ZX平面与Y方向正交，则相位差元件具有多个 在Y轴方向分割的区域，通过多个区域的光的波前引起相位差。
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公开(公告)号：US20120019824A1
公开(公告)日：2012-01-26
申请号：US13180736
申请日：2011-07-12
申请人： Suguru Dowaki
发明人： Suguru Dowaki
CPC分类号： G01N15/1459 , G01N15/1434
摘要： A fine particle detector includes a light emitting system letting light from a light source pass through a phase difference element and focusing the light on a sample flow through which fine particles flow. When the direction of the sample flow is an X-axis direction, the light is emitted to the sample flow in a Z-direction, and a ZX-plane is orthogonal to a Y-direction, then the phase difference element has a plurality of regions divided in the Y-axis direction and causes a phase difference between wavefronts of the light passing through the plurality of regions.
摘要翻译： 细粒子检测器包括使来自光源的光通过相位差元件的发光系统，并将光聚焦在微粒流过的样品流中。 当样品流动的方向为X轴方向时，光沿Z方向发射到样品流，ZX平面与Y方向正交，则相位差元件具有多个 在Y轴方向分割的区域，通过多个区域的光的波前引起相位差。
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公开(公告)号：US10175164B2
公开(公告)日：2019-01-08
申请号：US13565032
申请日：2012-08-02
摘要： As a result of acquiring visible absorption spectra of red blood cells and analyses of the spectra, inventors of the present disclosure have discovered the fact that echinocytes show a characteristic spectrum pattern having an absorption peak in a wavelength region of 450 to 490 nm between Soret and Q bands. Then, the present disclosure provides a blood analysis apparatus having an analysis section for detecting the absorption peak of a visible absorption spectrum acquired for blood. In accordance with this blood analysis apparatus, on the basis of the absorption peak, it is possible to detect echinocytes contained in blood.
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公开(公告)号：US20130040337A1
公开(公告)日：2013-02-14
申请号：US13565032
申请日：2012-08-02
CPC分类号： G01N21/31 , G01N21/33 , G01N2021/3144 , G01N2021/3155
摘要： As a result of acquiring visible absorption spectra of red blood cells and analyses of the spectra, inventors of the present disclosure have discovered the fact that echinocytes show a characteristic spectrum pattern having an absorption peak in a wavelength region of 450 to 490 nm between Soret and Q bands. Then, the present disclosure provides a blood analysis apparatus having an analysis section for detecting the absorption peak of a visible absorption spectrum acquired for blood. In accordance with this blood analysis apparatus, on the basis of the absorption peak, it is possible to detect echinocytes contained in blood.
摘要翻译： 作为获得红细胞的可见吸收光谱和光谱分析的结果，本公开的发明人已经发现这样的事实，即棘皮细胞显示出在Soret和Soret之间在450nm至490nm的波长区域中具有吸收峰的特征光谱图 Q波段。 然后，本公开提供一种血液分析装置，具有用于检测对血液获取的可见吸收光谱的吸收峰的分析部。 根据该血液分析装置，基于吸收峰，可以检测血液中包含的棘皮细胞。
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公开(公告)号：US20130038860A1
公开(公告)日：2013-02-14
申请号：US13561820
申请日：2012-07-30
申请人： Eriko Matsui , Suguru Dowaki , Hirokazu Tatsuta , Takeshi Kunihiro , Akira Niwa , Megumu Saito , Tatsutoshi Nakahata
发明人： Eriko Matsui , Suguru Dowaki , Hirokazu Tatsuta , Takeshi Kunihiro , Akira Niwa , Megumu Saito , Tatsutoshi Nakahata
IPC分类号： G01N33/49
CPC分类号： G01N15/05 , G01N21/31 , G01N21/33 , G01N33/49 , G01N2021/3144 , G01N2021/3155
摘要： A blood analysis apparatus includes an analysis section. The analysis section is configured to compare a measurement spectrum obtained regarding red blood cells with a standard spectrum of heme, biliverdin, and bilirubin, and cause the measurement spectrum to belong to any one of the standard spectra.
摘要翻译： 血液分析装置包括分析部。 分析部将比较红细胞的测定光谱与血红素，胆红素，胆红素的标准光谱进行比较，使测定光谱属于任一标准光谱。
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