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公开(公告)号:US11306339B2
公开(公告)日:2022-04-19
申请号:US16310152
申请日:2017-06-16
IPC分类号: C12P19/44 , C07H1/08 , C07H15/04 , A61K8/60 , C12P7/6409 , A61K8/04 , A61K9/00 , A61K9/12 , A61Q19/00
摘要: A method for the production of a rhamnolipid. The method includes culturing in a fermentation medium an organism capable of producing a rhamnolipid to form a fermentation broth comprising at least one rhamnolipid and having a pH>5; extracting at least one lipophilic impurity from said fermentation broth; acidulating said fermentation broth to form an aqueous medium of pH
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公开(公告)号:US11466294B2
公开(公告)日:2022-10-11
申请号:US16306186
申请日:2017-05-31
摘要: Supplemented mixotrophic method. A mixotrophic fermentation method is disclosed including providing a naturally acetogenic organism; providing a fermentation medium comprising a carbon source and a supplemented non-sugar reductant; and culturing the organism in the fermentation medium, where both the carbon source and the non-sugar reductant are metabolized and a fermentation broth is formed, which contains at least one carbon-containing bioproduct.
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公开(公告)号:US11918019B2
公开(公告)日:2024-03-05
申请号:US18022282
申请日:2021-08-22
发明人: Bryan P. Tracy , Aharon M. Eyal , Sasson Somekh , Shawn Jones , Daniel Knox Mitchell , Alon Karpol , Kartheek Ankella-Anderson
IPC分类号: C12N1/20 , A23C11/10 , A23C20/02 , A23J1/00 , A23J3/20 , A23J3/22 , A23L33/135 , A23L33/195
CPC分类号: A23L33/195 , A23C11/10 , A23C11/103 , A23C20/02 , A23J1/008 , A23J3/20 , A23J3/227 , A23L33/135 , C12N1/20
摘要: Provided is food component comprising cells of at least one bacterium, said cells comprising a crude protein concentration of at least 60 wt % of a total dry weight of said cells and nucleic acid at a concentration of less than about 5 wt % of a total dry weight of said cells, wherein at least 50% of a total number of said cells are dead cells. Further provided are food and beverages comprising such food components and methods of manufacture thereof.
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公开(公告)号:US11629365B2
公开(公告)日:2023-04-18
申请号:US17272319
申请日:2019-08-27
摘要: Provided are aqueous fermentation feedstocks comprising glucose monomers at a concentration of less than 50 gram/Liter (g/L) of the total feedstock, water-soluble dextrose oligomers at a concentration in a range between 50 g/L and 300 g/L of the total feedstock; and water. Further provided are methods of production thereof and uses thereof in the production of single cell protein and/or ethanol.
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公开(公告)号:US20240300876A1
公开(公告)日:2024-09-12
申请号:US18270843
申请日:2022-01-07
发明人: Bryan P. TRACY , Dale A. MONCEAUX , Aharon M. Eyal
摘要: Provided is a method for the production of refined, low-acetal ethanol, comprising providing a fermentation product produced by fermentation of a carbon source with an ethanol-producing organism, which fermentation product comprises between 30% wt and 99% wt ethanol, between 70% wt and 1% wt water and between 20 and 2000 parts per million acetal; contacting said fermentation product with an acid catalyst, whereby at least 20% of the acetal hydrolyses to form a hydrolysis product comprising ethanol, water, acetaldehyde and optionally residual acetal; and distilling said hydrolysis product, whereby distilled, low-acetal ethanol is formed.
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公开(公告)号:US20240124383A1
公开(公告)日:2024-04-18
申请号:US18277092
申请日:2022-02-13
发明人: Asher Vitner , Aharon M. Eyal , Bryan P. Tracy
IPC分类号: C07C67/08 , A23K20/105 , A23L29/00 , C07C67/54
CPC分类号: C07C67/08 , A23K20/105 , A23L29/035 , C07C67/54
摘要: Provided is a method for producing an ester of butyric acid from an acid mixture, comprising contacting an aqueous carboxylic acid mixture comprising butyric acid and at least one additional carboxylic acid selected from the group consisting of formic acid, acetic acid, propionic acid, lactic acid, hydroxybutyric acid and combinations thereof, wherein at least 30% of the total amount of acids in the aqueous carboxylic acid mixture are in free acid form, with a liquid extractant having a Hildebrand solubility parameter of less than 25 MPa(1/2); separating a resultant butyric acid-comprising extract from a residual aqueous phase; contacting a resultant separated butyric acid-comprising extract with an alkanol in the presence of an acid catalyst, to form a product comprising an ester of butyric acid and alkanol and optionally water; wherein when water is formed, separating water to provide a separated product comprising an ester of butyric acid.
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公开(公告)号:US20240277020A1
公开(公告)日:2024-08-22
申请号:US18422021
申请日:2024-01-25
发明人: Bryan P. TRACY , Aharon M. Eyal , Sasson Somekh , Shawn Jones , Daniel Knox Mitchell , Alon Karpol , Kartheek Ankella-Anderson
IPC分类号: A23L33/195 , A23C11/10 , A23C20/02 , A23J1/00 , A23J3/20 , A23J3/22 , A23L33/135 , C12N1/20
CPC分类号: A23L33/195 , A23C11/10 , A23C11/103 , A23C20/02 , A23J1/008 , A23J3/20 , A23J3/227 , A23L33/135 , C12N1/20
摘要: Provided is food component comprising cells of at least one bacterium, said cells comprising a crude protein concentration of at least 60 wt % of a total dry weight of said cells and nucleic acid at a concentration of less than about 5 wt % of a total dry weight of said cells, wherein at least 50% of a total number of said cells are dead cells. Further provided are food and beverages comprising such food components and methods of manufacture thereof.
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公开(公告)号:US20240141391A1
公开(公告)日:2024-05-02
申请号:US18384898
申请日:2023-10-30
CPC分类号: C12P1/04 , C12N1/20 , C12R2001/01
摘要: Producing a composition comprising cells of at least one bacterium, where at least 90% of the composition is in the form of a free flowing powder, by providing a drum dryer comprising two spaced-apart rotatable cylinders, with a gap of width G inches and a length of L inches therebetween; providing a fermentation broth comprising cells of at least one bacterium in a liquid suspension at a total solid content C percent weight of no greater than about 15% wt of the total weight of the fermentation broth; and introducing the fermentation broth into said drum dryer at a rate of W Kg per hour of no greater than 14×[(G×L)/C] to provide the composition.
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公开(公告)号:US20230320399A1
公开(公告)日:2023-10-12
申请号:US18022282
申请日:2021-08-22
发明人: Bryan P. TRACY , Aharon M. Eyal , Sasson Somekh , Shawn Jones , Daniel Knox Mitchell , Alon Karpol , Kartheek Ankella-Anderson
IPC分类号: A23L33/195 , C12N1/20 , A23C20/02 , A23C11/10 , A23J1/00 , A23J3/20 , A23J3/22 , A23L33/135
CPC分类号: A23L33/195 , C12N1/20 , A23C20/02 , A23C11/10 , A23C11/103 , A23J1/008 , A23J3/20 , A23J3/227 , A23L33/135
摘要: Provided is food component comprising cells of at least one bacterium, said cells comprising a crude protein concentration of at least 60 wt % of a total dry weight of said cells and nucleic acid at a concentration of less than about 5 wt % of a total dry weight of said cells, wherein at least 50% of a total number of said cells are dead cells. Further provided are food and beverages comprising such food components and methods of manufacture thereof.
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公开(公告)号:US08304588B2
公开(公告)日:2012-11-06
申请号:US13344464
申请日:2012-01-05
申请人: William A. Evanko , Aharon M. Eyal , David A. Glassner , Fudu Miao , Aristos A. Aristidou , Kent Evans , Patrick R. Gruber , Andrew C. Hawkins
发明人: William A. Evanko , Aharon M. Eyal , David A. Glassner , Fudu Miao , Aristos A. Aristidou , Kent Evans , Patrick R. Gruber , Andrew C. Hawkins
IPC分类号: C07C29/76
CPC分类号: C12M43/00 , C07C29/80 , C07C29/86 , C12C11/11 , C12M45/20 , C12P7/04 , C12P7/16 , Y02E50/10 , Y02E50/17 , Y10T29/49826 , C07C31/12
摘要: This invention is directed to methods for recovery of C3-C6 alcohols from dilute aqueous solutions, such as fermentation broths. Such methods provide improved volumetric productivity for the fermentation and allows recovery of the alcohol. Such methods also allow for reduced energy use in the production and drying of spent fermentation broth due to increased effective concentration of the alcohol product by the simultaneous fermentation and recovery process which increases the quantity of alcohol produced and recovered per quantity of fermentation broth dried. Thus, the invention allows for production and recovery of C3-C6 alcohols at low capital and reduced operating costs.
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