-
公开(公告)号：US20050244363A1
公开(公告)日：2005-11-03
申请号：US10835912
申请日：2004-04-30
申请人： Syed Hossainy , Eugene Michal , Thierry Glauser , Connie Kwok , Stephen Pacetti
发明人： Syed Hossainy , Eugene Michal , Thierry Glauser , Connie Kwok , Stephen Pacetti
IPC分类号： A61K31/727 , A61K31/728 , A61K31/785 , A61L27/00 , A61L31/10 , C08G63/48
CPC分类号： A61L31/10 , A61K31/727 , A61K31/728 , A61K31/785 , A61L31/16 , A61K2300/00 , C08L5/08 , C08L5/10
摘要： Hyaluronic acid (HA) conjugates or crosslinked HAs compositions for coating an implantable device are provided. The implantable device can be used for treating a disorder such as atherosclerosis, thrombosis, restenosis, high cholesterol, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, ureter obstruction, tumor obstruction, and combinations thereof.
摘要翻译： 提供了用于涂覆可植入装置的透明质酸（HA）缀合物或交联的HA组合物。 可植入装置可用于治疗动脉粥样硬化，血栓形成，再狭窄，高胆固醇，出血，血管解剖或穿孔，血管动脉瘤，易损斑块，慢性完全闭塞，跛行，静脉和人造移植物的吻合增殖等障碍，胆管 梗阻，输尿管阻塞，肿瘤阻塞及其组合。
-
2.发明申请Coatings for implantable devices comprising polymers of lactic acid and methods for fabricating the same 审中-公开用于包含乳酸聚合物的可植入装置的涂层及其制造方法公开(公告)号：US20050112170A1
公开(公告)日：2005-05-26
申请号：US10718976
申请日：2003-11-20
申请人： Syed Hossainy , Yiwen Tang , Eugene Michal , Thierry Glauser , Stephen Pacetti , Jessica DesNoyer
发明人： Syed Hossainy , Yiwen Tang , Eugene Michal , Thierry Glauser , Stephen Pacetti , Jessica DesNoyer
IPC分类号： A61F2/00 , A61F2/86 , A61L29/08 , A61L29/16 , A61L31/10 , A61L31/14 , A61L31/16 , A61L33/06 , A61M29/02
CPC分类号： A61L31/10 , A61F2/86 , A61F2250/0067 , A61L31/148 , A61L31/16 , A61L2300/416 , A61L2300/606 , C08L67/04
摘要： Coatings for an implantable medical device and a method of fabricating thereof are disclosed, the coatings comprising polymers of lactic acid.
摘要翻译： 公开了用于可植入医疗装置的涂层及其制造方法，所述涂层包含乳酸聚合物。
-
3.发明申请公开(公告)号：US20050147647A1
公开(公告)日：2005-07-07
申请号：US10746483
申请日：2003-12-24
申请人： Thierry Glauser , Connie Kwok , Charles Claude , Eugene Michal , Yiwen Tang , Irina Astafieva , Stephen Pacetti , John Whatley , Ashok Shah
发明人： Thierry Glauser , Connie Kwok , Charles Claude , Eugene Michal , Yiwen Tang , Irina Astafieva , Stephen Pacetti , John Whatley , Ashok Shah
CPC分类号： A61L31/16 , A61F2250/0067 , A61L31/10 , A61L2300/252 , A61L2300/606 , C08L75/04
摘要： A segmented polyurethane and an amphiphilic random or block copolymer are disclosed. The segmented polyurethane and the amphiphilic random or block copolymer can be used for fabricating a coating for an implantable medical device such as a stent.
摘要翻译： 公开了一种分段聚氨酯和两亲无规或嵌段共聚物。 分段聚氨酯和两亲无规或嵌段共聚物可用于制造可植入医疗装置例如支架的涂层。
-
公开(公告)号：US20080113207A1
公开(公告)日：2008-05-15
申请号：US12016811
申请日：2008-01-18
申请人： Stephen Pacetti , Syed Hossainy , Yiwen Tang , Andrew Tung , Thierry Glauser
发明人： Stephen Pacetti , Syed Hossainy , Yiwen Tang , Andrew Tung , Thierry Glauser
CPC分类号： A61L31/10 , A61F2250/0067 , A61L2420/08 , Y10T428/24942 , Y10T428/3154 , Y10T428/31544 , Y10T428/31551 , Y10T428/31565 , Y10T428/31573 , Y10T428/31576 , Y10T428/31786 , Y10T428/31797 , Y10T428/31855 , Y10T428/31909 , Y10T428/31928 , Y10T428/31935
摘要： A coating for an implantable medical device is provided comprising a first layer including a first polymer and a second layer including a second polymer. The second layer is disposed over at least a portion of the first layer. The second polymer has a lower degree of hydration than the first polymer.
摘要翻译： 提供了一种用于可植入医疗装置的涂层，包括包含第一聚合物的第一层和包含第二聚合物的第二层。 第二层设置在第一层的至少一部分上。 第二聚合物的水合度比第一聚合物低。
-
公开(公告)号：US20070202323A1
公开(公告)日：2007-08-30
申请号：US11365392
申请日：2006-02-28
CPC分类号： A61L31/16 , A61L31/10 , A61L2300/416 , A61L2300/422 , A61L2300/606 , Y10T428/265 , Y10T428/31855 , Y10T428/31935 , Y10T428/31938 , C08L29/04
摘要： A method of forming a surface layer that includes a hydroxyl polymer on a substrate coating on a medical device is provided.
摘要翻译： 提供了一种在医疗装置上的基底涂层上形成包含羟基聚合物的表面层的方法。
-
公开(公告)号：US09242005B1
公开(公告)日：2016-01-26
申请号：US11507860
申请日：2006-08-21
申请人： Syed Hossainy , Florian Niklas Ludwig , Stephen Pacetti , Paul Consigny , Fozan El-Nounou , Thierry Glauser , Jessica DesNoyer
发明人： Syed Hossainy , Florian Niklas Ludwig , Stephen Pacetti , Paul Consigny , Fozan El-Nounou , Thierry Glauser , Jessica DesNoyer
CPC分类号： A61K47/42 , A61K9/0019 , A61K9/1075 , A61K9/127 , A61K9/1273 , A61M5/178 , A61M25/104 , A61M31/00 , A61M2025/0087 , A61M2025/105 , A61M2025/1052
摘要： Pro-healing agent formulation compositions, methods and treatments for enhancing vascular healing are disclosed herein. In some embodiments, a pro-healing agent is encapsulated, suspended, disposed within or loaded into a biodegradable carrier for sustained-release delivery to a denuded or damaged endothelium treatment area in a blood vessel. In some applications, the pro-healing agent can accelerate re-endothelialization of a denuded vascular region. In some applications, the pro-healing agent can assist in the regaining of endothelium functionality. The formulation can be delivered by a delivery assembly such as an infusion catheter, a porous balloon catheter, a needle injection catheter, a double balloon catheter or the like.
摘要翻译： 本文公开了用于增强血管愈合的预愈合剂制剂组合物，方法和治疗。 在一些实施方案中，将前修复剂包封，悬浮，置于生物降解载体内或装载到可生物降解的载体中，以缓释递送至血管内的裸露或损伤的内皮治疗区域。 在一些应用中，预愈合剂可以加速裸露的血管区域的再内皮化。 在一些应用中，前修复剂可以帮助恢复内皮功能。 制剂可以通过输送组件例如输注导管，多孔气囊导管，针注射导管，双气囊导管等来递送。
-
7.发明申请Methods, Compositions and Devices for Treating Lesioned Sites Using Bioabsorbable Carriers 审中-公开用生物可吸收载体处理病变部位的方法，组成和装置公开(公告)号：US20100222872A1
公开(公告)日：2010-09-02
申请号：US12782656
申请日：2010-05-18
申请人： Lothar W. Kleiner , Syed Hossainy , Irina Astafieva , Stephen Pacetti , Thierry Glauser , Jessica Desnoyer , Florian N. Ludwig
发明人： Lothar W. Kleiner , Syed Hossainy , Irina Astafieva , Stephen Pacetti , Thierry Glauser , Jessica Desnoyer , Florian N. Ludwig
CPC分类号： A61K9/143 , A61K9/0019 , A61K9/1611 , A61L31/10 , A61L31/148 , A61L31/16 , A61L2300/00 , C08L67/04
摘要： Methods and compositions for the sustained release of treatment agents to treat an occluded blood vessel and affected tissue and/or organs are disclosed. Porous or non-porous bioabsorbable glass, metal or ceramic bead, rod or fiber particles can be loaded with a treatment agent, and optionally an image-enhancing agent, and coated with a sustained-release coating for delivery to an occluded blood vessel and affected tissue and/or organs by a delivery device. Implantable medical devices manufactured with coatings including the particles or embedded within the medical device are additionally disclosed.
摘要翻译： 公开了用于持续释放治疗剂以治疗闭塞的血管和受影响的组织和/或器官的方法和组合物。 多孔或无孔生物可吸收玻璃，金属或陶瓷珠，棒或纤维颗粒可以加载处理剂和任选的图像增强剂，并涂覆有持续释放的涂层以递送至闭塞的血管并受影响 组织和/或器官。 另外公开了用包括颗粒的涂层制造的植入式医疗装置或嵌入在医疗装置内的植入式医疗装置。
-
8.发明申请METHODS, COMPOSITIONS AND DEVICES FOR TREATING LESIONED SITES USING BIOABSORBABLE CARRIERS 审中-公开方法，组合物和使用生物可降解载体处理裂解位点的装置公开(公告)号：US20080051335A1
公开(公告)日：2008-02-28
申请号：US11614047
申请日：2006-12-20
申请人： Lothar Kleiner , Syed Hossainy , Irina Astafieva , Stephen Pacetti , Thierry Glauser , Jessica DesNoyer , Florian Ludwig
发明人： Lothar Kleiner , Syed Hossainy , Irina Astafieva , Stephen Pacetti , Thierry Glauser , Jessica DesNoyer , Florian Ludwig
CPC分类号： A61K9/143 , A61K9/0019 , A61K9/1611 , A61L31/10 , A61L31/148 , A61L31/16 , A61L2300/00 , C08L67/04
摘要： Methods and compositions for the sustained release of treatment agents to treat an occluded blood vessel and affected tissue and/or organs are disclosed. Porous or non-porous bioabsorbable glass, metal or ceramic bead, rod or fiber particles can be loaded with a treatment agent, and optionally an image-enhancing agent, and coated with a sustained-release coating for delivery to an occluded blood vessel and affected tissue and/or organs by a delivery device. Implantable medical devices manufactured with coatings including the particles or embedded within the medical device are additionally disclosed.
摘要翻译： 公开了用于持续释放治疗剂以治疗闭塞的血管和受影响的组织和/或器官的方法和组合物。 多孔或无孔生物可吸收玻璃，金属或陶瓷珠，棒或纤维颗粒可以加载处理剂和任选的图像增强剂，并涂覆有持续释放的涂层以递送至闭塞的血管并受影响 组织和/或器官。 另外公开了用包括颗粒的涂层制造的植入式医疗装置或嵌入在医疗装置内的植入式医疗装置。
-
9.发明申请Methods, Compositions and Devices for Treating Lesioned Sites Using Bioabsorbable Carriers 审中-公开用生物可吸收载体处理病变部位的方法，组成和装置公开(公告)号：US20110027188A1
公开(公告)日：2011-02-03
申请号：US12901402
申请日：2010-10-08
申请人： Lothar W. Kleiner , Syed Hossainy , Irina Astafieva , Stephen Pacetti , Thierry Glauser , Jessica DesNoyer , Florian N. Ludwig
发明人： Lothar W. Kleiner , Syed Hossainy , Irina Astafieva , Stephen Pacetti , Thierry Glauser , Jessica DesNoyer , Florian N. Ludwig
CPC分类号： A61K9/143 , A61K9/0019 , A61K9/1611 , A61L31/10 , A61L31/148 , A61L31/16 , A61L2300/00 , C08L67/04
摘要： An implantable medical device is disclosed having a plurality of smaller particles contained in a plurality of larger particles and configured to be released from the larger particles when the device is implanted in a patient. The smaller particles and the larger particles are made of bioabsorbable metal, glass or ceramic. A substance can be associated with the smaller particles. The larger particles can be embedded within at least a portion of the device.
摘要翻译： 公开了一种植入式医疗装置，其具有包含在多个较大颗粒中的多个较小颗粒，并且构造成当将该装置植入患者时从较大颗粒释放。 较小的颗粒和较大的颗粒由生物可吸收的金属，玻璃或陶瓷制成。 物质可以与较小的颗粒相关联。 较大的颗粒可以嵌入装置的至少一部分内。
-
10.发明申请Methods, compositions and devices for treating lesioned sites using bioabsorbable carriers 审中-公开用生物可吸收载体处理损伤部位的方法，组合物和装置公开(公告)号：US20070258903A1
公开(公告)日：2007-11-08
申请号：US11416860
申请日：2006-05-02
申请人： Lothar Kleiner , Syed Hossainy , Irina Astafieva , Stephen Pacetti , Thierry Glauser , Jessica DesNoyer , Florian Ludwig
发明人： Lothar Kleiner , Syed Hossainy , Irina Astafieva , Stephen Pacetti , Thierry Glauser , Jessica DesNoyer , Florian Ludwig
CPC分类号： A61K9/0019 , A61K9/143 , A61K9/1611 , A61L31/148 , A61L31/16 , A61L2300/602
摘要： Methods and compositions for the sustained release of treatment agents to treat an occluded blood vessel and affected tissue and/or organs are disclosed. Porous or non-porous bioabsorbable glass, metal or ceramic bead, rod or fiber particles can be loaded with a treatment agent, and optionally an image-enhancing agent, and coated with a sustained-release coating for delivery to an occluded blood vessel and affected tissue and/or organs by a delivery device.
摘要翻译： 公开了用于持续释放治疗剂以治疗闭塞的血管和受影响的组织和/或器官的方法和组合物。 多孔或无孔生物可吸收玻璃，金属或陶瓷珠，棒或纤维颗粒可以加载处理剂和任选的图像增强剂，并涂覆有持续释放的涂层以递送至闭塞的血管并受影响 组织和/或器官。
-
-
-
-
-
-
-
-
-
搜索结果
92 条记录 (耗时 0.025 秒)
